EP3801920A4 - Centrifuge system for separating cells in suspension - Google Patents

Centrifuge system for separating cells in suspension Download PDF

Info

Publication number
EP3801920A4
EP3801920A4 EP19815510.3A EP19815510A EP3801920A4 EP 3801920 A4 EP3801920 A4 EP 3801920A4 EP 19815510 A EP19815510 A EP 19815510A EP 3801920 A4 EP3801920 A4 EP 3801920A4
Authority
EP
European Patent Office
Prior art keywords
suspension
separating cells
centrifuge system
centrifuge
separating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19815510.3A
Other languages
German (de)
French (fr)
Other versions
EP3801920A1 (en
Inventor
S Kessler
T Marro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pneumatic Scale Corp
Original Assignee
Pneumatic Scale Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pneumatic Scale Corp filed Critical Pneumatic Scale Corp
Publication of EP3801920A1 publication Critical patent/EP3801920A1/en
Publication of EP3801920A4 publication Critical patent/EP3801920A4/en
Pending legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/04—Periodical feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
    • B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/30—Control equipment
    • B01D21/32—Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/02—Continuous feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/08—Skimmers or scrapers for discharging ; Regulating thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/08—Skimmers or scrapers for discharging ; Regulating thereof
    • B04B11/082—Skimmers for discharging liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B13/00—Control arrangements specially designed for centrifuges; Programme control of centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B04B7/08—Rotary bowls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2221/00—Applications of separation devices
    • B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0464—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl
EP19815510.3A 2018-06-08 2019-06-06 Centrifuge system for separating cells in suspension Pending EP3801920A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862682376P 2018-06-08 2018-06-08
PCT/US2019/035855 WO2019236895A1 (en) 2018-06-08 2019-06-06 Centrifuge system for separating cells in suspension

Publications (2)

Publication Number Publication Date
EP3801920A1 EP3801920A1 (en) 2021-04-14
EP3801920A4 true EP3801920A4 (en) 2022-07-13

Family

ID=68770662

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19815510.3A Pending EP3801920A4 (en) 2018-06-08 2019-06-06 Centrifuge system for separating cells in suspension

Country Status (9)

Country Link
EP (1) EP3801920A4 (en)
JP (1) JP7336467B2 (en)
KR (2) KR102568313B1 (en)
CN (2) CN115254458A (en)
AU (2) AU2019280856B2 (en)
BR (1) BR112020025083A2 (en)
CA (1) CA3102600A1 (en)
MX (2) MX2020011898A (en)
WO (1) WO2019236895A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11878311B2 (en) * 2011-11-21 2024-01-23 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11065629B2 (en) * 2011-11-21 2021-07-20 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11957998B2 (en) * 2019-06-06 2024-04-16 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
KR20230058077A (en) * 2020-08-22 2023-05-02 수닐 메타 Automatic Centrifugal Separation Apparatus and Method for Continuous Separation of Components from Diverse Mixtures
CN114682397B (en) * 2022-03-28 2024-03-15 浙江大学 Conical liquid-liquid axial centrifugal separator and separation monitoring device
WO2023196391A1 (en) * 2022-04-07 2023-10-12 Mirror Biologics, Inc. Artificial lymph node bioreator

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB675648A (en) * 1950-01-19 1952-07-16 Separator Ab Improved centrifugal separator for the continuous separation and discharge of solid matter from a liquid mixture
US5387174A (en) * 1993-01-29 1995-02-07 Elp Rochat Centrifugal separator with disposable bowl assembly
US5637217A (en) * 1995-01-25 1997-06-10 Fleetguard, Inc. Self-driven, cone-stack type centrifuge
JPH09192215A (en) * 1996-01-17 1997-07-29 Takaharu Nakane Centrifugal bowl
EP0992256A2 (en) * 1998-10-05 2000-04-12 Terumo Kabushiki Kaisha Blood component collection apparatus
EP1011868A1 (en) * 1997-04-16 2000-06-28 FILTERWERK MANN + HUMMEL GmbH Rotor, especially for incorporation into the enclosure of a free jet centrifuge
US20130089917A1 (en) * 2008-04-22 2013-04-11 Pneumatic Scale Corporation Single Use Centrifuge System for Highly Concentrated and/or Turbid Feeds
US20140045672A1 (en) * 2011-04-08 2014-02-13 Sorin Group Italia S.R.L. Disposable device for centrifugal blood separation
US20170333915A1 (en) * 2014-12-10 2017-11-23 Gea Mechanical Equipment Gmbh Separator

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA894304A (en) * 1972-02-29 Fujisawa Mitsumaro Embossing film with compressed air on recessed drum and applying second film
CA1057254A (en) * 1976-05-14 1979-06-26 Baxter Travenol Laboratories Disposable centrifugal blood processing system
DE3231070A1 (en) * 1982-08-19 1984-08-23 Herwig 1000 Berlin Michel-Kim Apparatus for delivery of materials stored in hoppers
DE3771148D1 (en) * 1986-07-22 1991-08-08 Haemonetics Corp CENTRIFUGAL HOUSING OR ROTOR FOR PLASMAPHERESE.
US5318500A (en) * 1992-10-15 1994-06-07 Eli Lilly And Company Method for controlling intermittently discharged centrifuges
EP0868215B1 (en) * 1995-12-01 2002-01-30 Baker Hughes Incorporated Method and apparatus for controlling and monitoring continuous feed centrifuge
JP3313572B2 (en) * 1996-04-03 2002-08-12 ヘモネティクス・コーポレーション Blood processing centrifuge bowl
US6629919B2 (en) * 1999-06-03 2003-10-07 Haemonetics Corporation Core for blood processing apparatus
EP1688183A1 (en) * 2005-02-03 2006-08-09 Jean-Denis Rochat Method and disposable device for centrifugal separation of a physiologic liquid
US7628749B2 (en) * 2005-09-01 2009-12-08 Wagner Development Inc. Solids recovery using cross-flow microfilter and automatic piston discharge centrifuge
CN201094937Y (en) * 2007-09-18 2008-08-06 江苏牡丹离心机制造有限公司 Bag squeezing device of punching bag type centrifuge
SI3199511T1 (en) * 2009-06-04 2020-07-31 Genomatica, Inc. Process of separating components of a fermentation broth
US10906049B2 (en) * 2014-06-04 2021-02-02 Biosafe S.A. System for multi-processing and separation of biological fluids
US9833557B2 (en) * 2014-12-19 2017-12-05 Fenwal, Inc. Systems and methods for determining free plasma hemoglobin
DE102015105988B3 (en) * 2015-04-20 2016-05-25 Hiller Gmbh Device for continuously separating flowable substances of different densities in a centrifuge
JP6912391B2 (en) * 2015-07-13 2021-08-04 ヘモネティクス・コーポレーションＨａｅｍｏｎｅｔｉｃｓ Ｃｏｒｐｏｒａｔｉｏｎ Systems and methods for removing fat from collected blood
EP3347134A4 (en) * 2015-09-07 2019-04-17 Mann+Hummel GmbH Liner with seal for rotor of centrifugal separator
CN106238229B (en) * 2016-08-31 2018-07-24 苏州盛天力离心机制造有限公司 Filter bowl component

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB675648A (en) * 1950-01-19 1952-07-16 Separator Ab Improved centrifugal separator for the continuous separation and discharge of solid matter from a liquid mixture
US5387174A (en) * 1993-01-29 1995-02-07 Elp Rochat Centrifugal separator with disposable bowl assembly
US5637217A (en) * 1995-01-25 1997-06-10 Fleetguard, Inc. Self-driven, cone-stack type centrifuge
JPH09192215A (en) * 1996-01-17 1997-07-29 Takaharu Nakane Centrifugal bowl
EP1011868A1 (en) * 1997-04-16 2000-06-28 FILTERWERK MANN + HUMMEL GmbH Rotor, especially for incorporation into the enclosure of a free jet centrifuge
EP0992256A2 (en) * 1998-10-05 2000-04-12 Terumo Kabushiki Kaisha Blood component collection apparatus
US20130089917A1 (en) * 2008-04-22 2013-04-11 Pneumatic Scale Corporation Single Use Centrifuge System for Highly Concentrated and/or Turbid Feeds
US20140045672A1 (en) * 2011-04-08 2014-02-13 Sorin Group Italia S.R.L. Disposable device for centrifugal blood separation
US20170333915A1 (en) * 2014-12-10 2017-11-23 Gea Mechanical Equipment Gmbh Separator

Also Published As

Publication number Publication date
JP7336467B2 (en) 2023-08-31
KR20220039841A (en) 2022-03-29
CN112236236A (en) 2021-01-15
MX2022003223A (en) 2022-04-12
JP2021526957A (en) 2021-10-11
AU2019280856A1 (en) 2020-12-17
CA3102600A1 (en) 2019-12-12
CN115254458A (en) 2022-11-01
KR102568313B1 (en) 2023-08-18
AU2022204733A1 (en) 2022-07-21
AU2019280856B2 (en) 2022-06-30
WO2019236895A1 (en) 2019-12-12
MX2020011898A (en) 2021-01-15
KR20210018796A (en) 2021-02-18
BR112020025083A2 (en) 2021-03-23
EP3801920A1 (en) 2021-04-14
KR102568314B1 (en) 2023-08-18

Similar Documents

Publication Publication Date Title
EP3801920A4 (en) Centrifuge system for separating cells in suspension
EP3427806A4 (en) Solid-liquid separator and solid-liquid separation system
EP3529611A4 (en) Methods for screening b cell lymphocytes
EP3555267A4 (en) Buoyancy enabled separation method and system
EP3410120A4 (en) Cell separation chip and system
EP3571753A4 (en) System for balancing a series of cells
EP3481627A4 (en) Separation system
EP3808856A4 (en) Undifferentiated cell detection method
EP3534431A4 (en) Separator for nonaqueous-electrolyte cell, and nonaqueous-electrolyte cell
EP3243902A4 (en) Luterion and separating and culturing methods for same
EP3662057A4 (en) Methods for identifying and separating pro-allergic specific t cells
EP3397066A4 (en) Process for separating proteins from biomass materials
EP3305887A4 (en) Concentrating device and method for concentrating cell suspension
EP3282005A4 (en) Cell separation chip and method for separating cells by using same
EP3894035A4 (en) Separation system and method thereof
EP3845500A4 (en) Ion removal system
EP4121187A4 (en) Centrifuge system for separating cells in suspension
EP3744430A4 (en) Centrifugal separator
EP3621143A4 (en) Method for regenerating eol cell
EP3482830A4 (en) Centrifugal separator and centrifugal separation method
EP3432396A4 (en) Porous separator for fuel cells
EP3314252A4 (en) Process for separating nucleated cells from non-nucleated red blood cells
EP3307863B8 (en) Device for separating regenerative and adult stem cells
EP4056290A4 (en) Separation method for layered structure
GB201909210D0 (en) Separating system

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20210104

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: B01D 21/32 20060101ALI20220220BHEP

Ipc: B04B 11/02 20060101ALI20220220BHEP

Ipc: B04B 5/00 20060101ALI20220220BHEP

Ipc: B01D 21/26 20060101ALI20220220BHEP

Ipc: B04B 5/04 20060101AFI20220220BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20220610

RIC1 Information provided on ipc code assigned before grant

Ipc: C12M 1/00 20060101ALI20220603BHEP

Ipc: B04B 7/08 20060101ALI20220603BHEP

Ipc: B01D 21/32 20060101ALI20220603BHEP

Ipc: B04B 11/02 20060101ALI20220603BHEP

Ipc: B04B 5/00 20060101ALI20220603BHEP

Ipc: B01D 21/26 20060101ALI20220603BHEP

Ipc: B04B 5/04 20060101AFI20220603BHEP

P01 Opt-out of the competence of the unified patent court (upc) registered

Effective date: 20230417

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20240313