MX2020011898A - Centrifuge system for separating cells in suspension. - Google Patents

Centrifuge system for separating cells in suspension.

Info

Publication number
MX2020011898A
MX2020011898A MX2020011898A MX2020011898A MX2020011898A MX 2020011898 A MX2020011898 A MX 2020011898A MX 2020011898 A MX2020011898 A MX 2020011898A MX 2020011898 A MX2020011898 A MX 2020011898A MX 2020011898 A MX2020011898 A MX 2020011898A
Authority
MX
Mexico
Prior art keywords
centrate
concentrate
discharge tube
pump
single use
Prior art date
Application number
MX2020011898A
Other languages
Spanish (es)
Inventor
kessler S
Marro T
Original Assignee
Pneumatic Scale Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pneumatic Scale Corp filed Critical Pneumatic Scale Corp
Publication of MX2020011898A publication Critical patent/MX2020011898A/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/04—Periodical feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
    • B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/30—Control equipment
    • B01D21/32—Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/02—Continuous feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/08—Skimmers or scrapers for discharging ; Regulating thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/08—Skimmers or scrapers for discharging ; Regulating thereof
    • B04B11/082—Skimmers for discharging liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B13/00—Control arrangements specially designed for centrifuges; Programme control of centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B04B7/08—Rotary bowls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2221/00—Applications of separation devices
    • B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0464—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Centrifugal Separators (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

An apparatus for separating cell suspension material into centrate and concentrate, includes a single use structure (178, 240, 250) releasably positioned in a cavity in a solid wall rotatable centrifuge bowl (172). The bowl and portions of single use structure rotate about an axis (174). A stationary inlet feed tube (184), a centrate discharge tube (212) and a concentrate discharge tube (230) extend along the axis of the rotating single use structure. A centrate centripetal pump (208) is in fluid connection with the centrate discharge tube. A concentrate centripetal pump (216) is in fluid connection with the concentrate discharge tube. A controller (274) operates responsive to sensors (264, 270) in respective centrate and concentrate discharge lines (262, 268), to control flow rates of a concentrate pump (272) and a centrate pump (266) to produce output flows of cell concentrate and generally cell free centrate.
MX2020011898A 2018-06-08 2019-06-06 Centrifuge system for separating cells in suspension. MX2020011898A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862682376P 2018-06-08 2018-06-08
PCT/US2019/035855 WO2019236895A1 (en) 2018-06-08 2019-06-06 Centrifuge system for separating cells in suspension

Publications (1)

Publication Number Publication Date
MX2020011898A true MX2020011898A (en) 2021-01-15

Family

ID=68770662

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020011898A MX2020011898A (en) 2018-06-08 2019-06-06 Centrifuge system for separating cells in suspension.
MX2022003223A MX2022003223A (en) 2018-06-08 2020-11-06 Centrifuge system for separating cells in suspension.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2022003223A MX2022003223A (en) 2018-06-08 2020-11-06 Centrifuge system for separating cells in suspension.

Country Status (8)

Country Link
EP (1) EP3801920A4 (en)
JP (1) JP7336467B2 (en)
KR (2) KR102568313B1 (en)
CN (2) CN115254458A (en)
AU (1) AU2019280856B2 (en)
CA (1) CA3102600C (en)
MX (2) MX2020011898A (en)
WO (1) WO2019236895A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11065629B2 (en) * 2011-11-21 2021-07-20 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US20220212207A9 (en) * 2011-11-21 2022-07-07 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11878311B2 (en) * 2011-11-21 2024-01-23 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11957998B2 (en) * 2019-06-06 2024-04-16 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
CA3190177A1 (en) * 2020-08-22 2022-03-03 Sunil Mehta An automated centrifugation device and methods to continuously separate components from different mixtures
CN114682397B (en) * 2022-03-28 2024-03-15 浙江大学 Conical liquid-liquid axial centrifugal separator and separation monitoring device
US20230323264A1 (en) * 2022-04-07 2023-10-12 Mirror Biologics, Inc. Artificial lymph node bioreactor

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CA894304A (en) * 1972-02-29 Fujisawa Mitsumaro Embossing film with compressed air on recessed drum and applying second film
GB675648A (en) * 1950-01-19 1952-07-16 Separator Ab Improved centrifugal separator for the continuous separation and discharge of solid matter from a liquid mixture
CA1057254A (en) * 1976-05-14 1979-06-26 Baxter Travenol Laboratories Disposable centrifugal blood processing system
DE3231070A1 (en) * 1982-08-19 1984-08-23 Herwig 1000 Berlin Michel-Kim Apparatus for delivery of materials stored in hoppers
ATE64863T1 (en) * 1986-07-22 1991-07-15 Haemonetics Corp CENTRIFUGE HOUSING OR ROTOR FOR PLASMAPHERESIS.
US5318500A (en) * 1992-10-15 1994-06-07 Eli Lilly And Company Method for controlling intermittently discharged centrifuges
CH687505A5 (en) * 1993-01-29 1996-12-31 Elp Rochat Centrifugal separator for fluids.
US5637217A (en) * 1995-01-25 1997-06-10 Fleetguard, Inc. Self-driven, cone-stack type centrifuge
EP0868215B1 (en) * 1995-12-01 2002-01-30 Baker Hughes Incorporated Method and apparatus for controlling and monitoring continuous feed centrifuge
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JP3313572B2 (en) * 1996-04-03 2002-08-12 ヘモネティクス・コーポレーション Blood processing centrifuge bowl
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Also Published As

Publication number Publication date
JP7336467B2 (en) 2023-08-31
MX2022003223A (en) 2022-04-12
EP3801920A1 (en) 2021-04-14
KR102568313B1 (en) 2023-08-18
WO2019236895A1 (en) 2019-12-12
CA3102600C (en) 2024-06-11
AU2019280856A1 (en) 2020-12-17
AU2022204733A1 (en) 2022-07-21
AU2019280856B2 (en) 2022-06-30
JP2021526957A (en) 2021-10-11
KR20220039841A (en) 2022-03-29
EP3801920A4 (en) 2022-07-13
BR112020025083A2 (en) 2021-03-23
KR20210018796A (en) 2021-02-18
CN115254458A (en) 2022-11-01
CN112236236A (en) 2021-01-15
KR102568314B1 (en) 2023-08-18
CA3102600A1 (en) 2019-12-12

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