MX2022010540A - Centrifuge system for separating cells in suspension. - Google Patents

Centrifuge system for separating cells in suspension.

Info

Publication number
MX2022010540A
MX2022010540A MX2022010540A MX2022010540A MX2022010540A MX 2022010540 A MX2022010540 A MX 2022010540A MX 2022010540 A MX2022010540 A MX 2022010540A MX 2022010540 A MX2022010540 A MX 2022010540A MX 2022010540 A MX2022010540 A MX 2022010540A
Authority
MX
Mexico
Prior art keywords
concentrate
centrate
discharge tube
single use
centripetal pump
Prior art date
Application number
MX2022010540A
Other languages
Spanish (es)
Inventor
S Kessler
T Marro
Original Assignee
Pneumatic Scale Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pneumatic Scale Corp filed Critical Pneumatic Scale Corp
Publication of MX2022010540A publication Critical patent/MX2022010540A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/10—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by centrifugation ; Cyclones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/02—Continuous feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B04B7/08—Rotary bowls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0464—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Centrifugal Separators (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

An apparatus for separating cell suspension material into centrate and concentrate, includes a single use structure (178, 240, 250, 370, 414) releasably positioned in a cavity in a solid wall rotatable centrifuge bowl (172). The bowl and portions of single use structure rotate about an axis (174, 428). A stationary inlet feed tube (184, 430), a centrate discharge tube (212, 436) and a concentrate discharge tube (230,448) extend along the axis of the rotating single use structure. A centrate centripetal pump (208, 438) is in fluid connection with the centrate discharge tube. A concentrate centripetal pump (216, 450) is in fluid connection with the concentrate discharge tube. At least one concentrate channel (380, 454) and a concentrate centripetal pump chamber (376,452) have configurations in the structure that facilitate the flow of cell concentrate.
MX2022010540A 2020-03-19 2021-03-17 Centrifuge system for separating cells in suspension. MX2022010540A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062991820P 2020-03-19 2020-03-19
PCT/US2021/022739 WO2021188655A1 (en) 2020-03-19 2021-03-17 Centrifuge system for separating cells in suspension

Publications (1)

Publication Number Publication Date
MX2022010540A true MX2022010540A (en) 2022-09-12

Family

ID=77768387

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022010540A MX2022010540A (en) 2020-03-19 2021-03-17 Centrifuge system for separating cells in suspension.

Country Status (8)

Country Link
EP (1) EP4121187A4 (en)
JP (1) JP7813713B2 (en)
KR (1) KR20230005826A (en)
CN (1) CN115297939A (en)
AU (1) AU2021239948B2 (en)
BR (1) BR112022018790A2 (en)
MX (1) MX2022010540A (en)
WO (1) WO2021188655A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11878311B2 (en) * 2011-11-21 2024-01-23 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US12350686B2 (en) * 2011-11-21 2025-07-08 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11957998B2 (en) * 2019-06-06 2024-04-16 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8504880D0 (en) * 1985-02-26 1985-03-27 Ae Plc Disposable cartridges
CH687505A5 (en) * 1993-01-29 1996-12-31 Elp Rochat Centrifugal separator for fluids.
US6602413B2 (en) * 2000-04-11 2003-08-05 Medicept, Inc. Sealed centrifugal clarifier
AU2001264717A1 (en) 2000-05-19 2001-12-03 Kendro Laboratory Products, L.P. Low-shear feeding system for use with centrifuges
DE10334370A1 (en) * 2003-07-25 2005-02-24 Westfalia Separator Ag Solid bowl screw centrifuge with direct drive
US10040077B1 (en) 2015-05-19 2018-08-07 Pneumatic Scale Corporation Centrifuge system including a control circuit that controls positive back pressure within the centrifuge core
EP2285464A4 (en) 2008-04-22 2014-01-01 Pneumatic Scale Corp Single use centrifuge system
US9222067B2 (en) 2008-04-22 2015-12-29 Pneumatic Scale Corporation Single use centrifuge system for highly concentrated and/or turbid feeds
BR112012024628A2 (en) 2010-04-02 2016-06-07 Pneumatic Scale Corp centrifuge method and system
WO2012137086A1 (en) * 2011-04-08 2012-10-11 Sorin Group Italia S.R.L. Disposable device for centrifugal blood separation
US11065629B2 (en) * 2011-11-21 2021-07-20 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
CA2863666A1 (en) * 2012-02-02 2013-08-08 Pall Technology Uk Limited Centrifugation system and related method
DE102012106648A1 (en) * 2012-07-23 2014-01-23 Gea Mechanical Equipment Gmbh separator arrangement

Also Published As

Publication number Publication date
WO2021188655A1 (en) 2021-09-23
CN115297939A (en) 2022-11-04
CA3169659A1 (en) 2021-09-23
KR20230005826A (en) 2023-01-10
AU2021239948B2 (en) 2024-06-20
EP4121187A4 (en) 2024-04-17
EP4121187A1 (en) 2023-01-25
BR112022018790A2 (en) 2023-01-31
JP7813713B2 (en) 2026-02-13
JP2023518693A (en) 2023-05-08
AU2021239948A1 (en) 2022-08-25

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