MX2022003223A - Sistema de centrifugacion para separar celulas en suspension. - Google Patents

Sistema de centrifugacion para separar celulas en suspension.

Info

Publication number
MX2022003223A
MX2022003223A MX2022003223A MX2022003223A MX2022003223A MX 2022003223 A MX2022003223 A MX 2022003223A MX 2022003223 A MX2022003223 A MX 2022003223A MX 2022003223 A MX2022003223 A MX 2022003223A MX 2022003223 A MX2022003223 A MX 2022003223A
Authority
MX
Mexico
Prior art keywords
centrate
concentrate
discharge tube
pump
single use
Prior art date
Application number
MX2022003223A
Other languages
English (en)
Inventor
S Kessler
T Marro
Original Assignee
Pneumatic Scale Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pneumatic Scale Corp filed Critical Pneumatic Scale Corp
Publication of MX2022003223A publication Critical patent/MX2022003223A/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/04—Periodical feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
    • B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/30—Control equipment
    • B01D21/32—Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/02—Continuous feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/08—Skimmers or scrapers for discharging ; Regulating thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/08—Skimmers or scrapers for discharging ; Regulating thereof
    • B04B11/082—Skimmers for discharging liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B13/00—Control arrangements specially designed for centrifuges; Programme control of centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B04B7/08—Rotary bowls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2221/00—Applications of separation devices
    • B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0464—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Centrifugal Separators (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Un aparato para separar material de suspensión celular en concentrado y centrifugado que incluye una estructura de un solo uso (178, 240, 250) colocada de manera liberable en una cavidad en un recipiente de centrífuga giratorio de pared sólida (172). El recipiente y las partes de estructura de un solo uso giran alrededor de un eje (174). Un tubo de alimentación de entrada estacionario (184), un tubo de descarga de centrifugado (212) y un tubo de descarga de concentrado (230) se extienden a lo largo del eje de la estructura giratoria de un solo uso. Una bomba centrípeta de centrifugado (208) está en conexión fluida con el tubo de descarga de centrifugado. Una bomba centrípeta de concentrado (216) está en conexión de fluido con el tubo de descarga de concentrado. Un controlador (274) funciona en respuesta a los sensores (264, 270) en las respectivas líneas de descarga de centrifugado y concentrado (262, 268), para controlar las tasas de flujo de una bomba de concentrado (272) una bomba de centrifugado (266) para producir flujos de salida de concentrado celular y centrifugado celular generalmente libre de células.
MX2022003223A 2018-06-08 2020-11-06 Sistema de centrifugacion para separar celulas en suspension. MX2022003223A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862682376P 2018-06-08 2018-06-08

Publications (1)

Publication Number Publication Date
MX2022003223A true MX2022003223A (es) 2022-04-12

Family

ID=68770662

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020011898A MX2020011898A (es) 2018-06-08 2019-06-06 Sistema de centrifugacion para separar celulas en suspension.
MX2022003223A MX2022003223A (es) 2018-06-08 2020-11-06 Sistema de centrifugacion para separar celulas en suspension.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2020011898A MX2020011898A (es) 2018-06-08 2019-06-06 Sistema de centrifugacion para separar celulas en suspension.

Country Status (8)

Country Link
EP (1) EP3801920A4 (es)
JP (1) JP7336467B2 (es)
KR (2) KR102568313B1 (es)
CN (2) CN115254458A (es)
AU (1) AU2019280856B2 (es)
CA (1) CA3102600C (es)
MX (2) MX2020011898A (es)
WO (1) WO2019236895A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11065629B2 (en) * 2011-11-21 2021-07-20 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US20220212207A9 (en) * 2011-11-21 2022-07-07 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11878312B2 (en) * 2011-11-21 2024-01-23 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11957998B2 (en) * 2019-06-06 2024-04-16 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
KR20230058077A (ko) * 2020-08-22 2023-05-02 수닐 메타 다양한 혼합물로부터 성분을 연속적으로 분리하기 위한 자동 원심분리 장치 및 방법
CN114682397B (zh) * 2022-03-28 2024-03-15 浙江大学 锥形液液轴向离心分离器及分离监控装置
WO2023196391A1 (en) * 2022-04-07 2023-10-12 Mirror Biologics, Inc. Artificial lymph node bioreator

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Also Published As

Publication number Publication date
CA3102600C (en) 2024-06-11
JP2021526957A (ja) 2021-10-11
CN112236236A (zh) 2021-01-15
KR20220039841A (ko) 2022-03-29
KR20210018796A (ko) 2021-02-18
EP3801920A4 (en) 2022-07-13
AU2019280856B2 (en) 2022-06-30
EP3801920A1 (en) 2021-04-14
BR112020025083A2 (pt) 2021-03-23
AU2022204733A1 (en) 2022-07-21
KR102568314B1 (ko) 2023-08-18
AU2019280856A1 (en) 2020-12-17
KR102568313B1 (ko) 2023-08-18
WO2019236895A1 (en) 2019-12-12
CA3102600A1 (en) 2019-12-12
CN115254458A (zh) 2022-11-01
JP7336467B2 (ja) 2023-08-31
MX2020011898A (es) 2021-01-15

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