KR102564405B1 - 제조 도중 제약 캡슐을 레이저 마킹하기 위한 방법 및 시스템 - Google Patents
제조 도중 제약 캡슐을 레이저 마킹하기 위한 방법 및 시스템 Download PDFInfo
- Publication number
- KR102564405B1 KR102564405B1 KR1020200034190A KR20200034190A KR102564405B1 KR 102564405 B1 KR102564405 B1 KR 102564405B1 KR 1020200034190 A KR1020200034190 A KR 1020200034190A KR 20200034190 A KR20200034190 A KR 20200034190A KR 102564405 B1 KR102564405 B1 KR 102564405B1
- Authority
- KR
- South Korea
- Prior art keywords
- capsule
- pair
- filler
- sheets
- forming
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000002775 capsule Substances 0.000 title claims abstract description 403
- 238000010330 laser marking Methods 0.000 title claims abstract description 192
- 238000000034 method Methods 0.000 title claims abstract description 53
- 238000004519 manufacturing process Methods 0.000 title description 26
- 239000000463 material Substances 0.000 claims abstract description 261
- 230000015572 biosynthetic process Effects 0.000 claims abstract description 29
- 239000000945 filler Substances 0.000 claims description 205
- 238000005538 encapsulation Methods 0.000 claims description 11
- 239000007788 liquid Substances 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 5
- 108010010803 Gelatin Proteins 0.000 description 15
- 229920000159 gelatin Polymers 0.000 description 15
- 235000019322 gelatine Nutrition 0.000 description 15
- 235000011852 gelatine desserts Nutrition 0.000 description 15
- 239000008273 gelatin Substances 0.000 description 14
- 239000011257 shell material Substances 0.000 description 11
- 239000000047 product Substances 0.000 description 10
- 229920002472 Starch Polymers 0.000 description 9
- 239000008107 starch Substances 0.000 description 9
- 235000019698 starch Nutrition 0.000 description 9
- 239000000825 pharmaceutical preparation Substances 0.000 description 7
- 229940127557 pharmaceutical product Drugs 0.000 description 7
- 240000003183 Manihot esculenta Species 0.000 description 5
- 235000016735 Manihot esculenta subsp esculenta Nutrition 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 5
- 239000003605 opacifier Substances 0.000 description 5
- 239000004014 plasticizer Substances 0.000 description 5
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 4
- 239000000679 carrageenan Substances 0.000 description 4
- 235000010418 carrageenan Nutrition 0.000 description 4
- 229920001525 carrageenan Polymers 0.000 description 4
- 229940113118 carrageenan Drugs 0.000 description 4
- 239000000499 gel Substances 0.000 description 4
- 238000007648 laser printing Methods 0.000 description 4
- 229920000642 polymer Polymers 0.000 description 4
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 4
- 235000010582 Pisum sativum Nutrition 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000013589 supplement Substances 0.000 description 3
- 239000011782 vitamin Substances 0.000 description 3
- 229940088594 vitamin Drugs 0.000 description 3
- 229930003231 vitamin Natural products 0.000 description 3
- 235000013343 vitamin Nutrition 0.000 description 3
- 241000283690 Bos taurus Species 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 description 2
- 239000001569 carbon dioxide Substances 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000012552 review Methods 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 230000001360 synchronised effect Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- -1 but not limited to Substances 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000011194 food seasoning agent Nutrition 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000006186 oral dosage form Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 238000000275 quality assurance Methods 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000007901 soft capsule Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/007—Marking tablets or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C67/00—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00
- B29C67/0003—Moulding articles between moving mould surfaces, e.g. turning surfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41M—PRINTING, DUPLICATING, MARKING, OR COPYING PROCESSES; COLOUR PRINTING
- B41M5/00—Duplicating or marking methods; Sheet materials for use therein
- B41M5/26—Thermography ; Marking by high energetic means, e.g. laser otherwise than by burning, and characterised by the material used
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S53/00—Package making
- Y10S53/90—Capsules
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Mechanical Engineering (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Laser Beam Processing (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962841393P | 2019-05-01 | 2019-05-01 | |
| US62/841,393 | 2019-05-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20200127857A KR20200127857A (ko) | 2020-11-11 |
| KR102564405B1 true KR102564405B1 (ko) | 2023-08-04 |
Family
ID=69467371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020200034190A Active KR102564405B1 (ko) | 2019-05-01 | 2020-03-20 | 제조 도중 제약 캡슐을 레이저 마킹하기 위한 방법 및 시스템 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12214608B2 (enExample) |
| EP (1) | EP3733148B1 (enExample) |
| JP (1) | JP7241712B2 (enExample) |
| KR (1) | KR102564405B1 (enExample) |
| CA (1) | CA3069207C (enExample) |
| ES (1) | ES2982687T3 (enExample) |
| PL (1) | PL3733148T3 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3069207C (en) * | 2019-05-01 | 2022-10-18 | Paul Lukas | Methods and systems for laser marking pharmaceutical capsules during manufacturing |
| KR20230130617A (ko) * | 2021-01-15 | 2023-09-12 | 쿠오리카프스 가부시키가이샤 | 캡슐마킹 장치 및 방법 |
| USD1055120S1 (en) * | 2022-07-02 | 2024-12-24 | Samuel Palmeter | Laser marking device |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014534903A (ja) | 2011-09-16 | 2014-12-25 | トライスター テクノロジーズTristar Technologies | レーザカプセルマーキングシステムおよび方法 |
| JP2018001753A (ja) | 2016-06-28 | 2018-01-11 | 芝浦メカトロニクス株式会社 | 錠剤印刷装置及び錠剤印刷方法 |
| JP2019055177A (ja) | 2017-09-19 | 2019-04-11 | 芝浦メカトロニクス株式会社 | 錠剤印刷装置及び錠剤印刷方法 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2152101A (en) * | 1935-10-28 | 1939-03-28 | Robert P Scherer | Method and apparatus for making capsules by submerged filling action |
| US2334600A (en) * | 1941-03-20 | 1943-11-16 | Boysen Bigelow | Capsule |
| US2497212A (en) * | 1945-10-31 | 1950-02-14 | Alfonso M Donofrio | Method of manufacturing capsules |
| US4567714A (en) * | 1980-11-24 | 1986-02-04 | Chasman Sydney A | Method and apparatus for forming capsules |
| US5246635A (en) * | 1989-01-26 | 1993-09-21 | R. P. Scherer Corporation | Method and apparatus for the manufacture of textured softgels |
| GB9325965D0 (en) * | 1993-12-20 | 1994-02-23 | Scherer Ltd R P | Soft gelatin capsules containing particulate material |
| US5761886A (en) * | 1996-02-09 | 1998-06-09 | Parkhideh; Shahrooz | Apparatus and method for manufacturing encapsulated products |
| GB9606371D0 (en) * | 1996-03-26 | 1996-06-05 | Brown Malcolm D | An encapsulation process |
| GB9705770D0 (en) * | 1997-03-20 | 1997-05-07 | Scherer Corp R P | Gelatin encapsulation techniques |
| AU2024900A (en) * | 1998-11-16 | 2000-06-05 | A.B.Technologies, L.L.C. | Multi chamber soft capsules and method of making the same |
| US6429889B1 (en) * | 1999-07-23 | 2002-08-06 | Tri-Star Technologies | Laser marking discrete consumable articles |
| US6776340B2 (en) * | 1999-07-23 | 2004-08-17 | Tri Star Technologies, A General Partnership | Duplicate laser marking discrete consumable articles |
| ATE320237T1 (de) * | 2000-12-20 | 2006-04-15 | Swiss Caps Rechte & Lizenzen | Rotary-die-verfahren und füllkeil zum herstellen von kapseln, insbesondere weichkapseln |
| US6574945B2 (en) * | 2001-03-21 | 2003-06-10 | Lumitek Llc | Method for manufacturing a projectile containing chemiluminescent compounds |
| US20030014946A1 (en) * | 2001-07-20 | 2003-01-23 | Steele Donald R. | Injection wedge for rotary die system |
| US6884060B2 (en) * | 2001-11-02 | 2005-04-26 | R.P. Scherer Technologies, Inc. | Apparatus for manufacturing encapsulated products |
| GB0208587D0 (en) * | 2002-04-13 | 2002-05-22 | Stanelco Fibre Optics Ltd | Capsules |
| CA2697782C (en) * | 2007-07-30 | 2015-12-22 | Procaps S.A. | Method and apparatus for printing on soft gelatin capsules during forming |
| US20100018170A1 (en) * | 2008-07-23 | 2010-01-28 | Technophar Equipment And Service (2007) Ltd. | Fill supply mechanism for soft capsule machine |
| BRPI0921072A2 (pt) * | 2008-11-20 | 2018-10-16 | Pfizer | aparelho para manipular cápsulas e equipamento de processamento de cápsula incluindo tal aparelho |
| US20100140830A1 (en) * | 2008-12-04 | 2010-06-10 | Aldo Perrone | Rotary die support and insert die member devices and methods for encapsulation technologies |
| JP2011120619A (ja) * | 2009-12-08 | 2011-06-23 | Sankyo:Kk | シート段階で印字を行うソフトカプセル製造方法並びにその製造装置 |
| PT2595597T (pt) * | 2010-07-19 | 2017-12-20 | Procaps S A | Aparelho e processo para encapsular cápsulas ou outras formas de dosagem sólida dentro de cápsulas |
| US8974820B2 (en) * | 2010-07-19 | 2015-03-10 | Procaps SAS | Apparatus and process for encapsulating microparticles with liquid in soft gel capsules |
| KR20120033921A (ko) * | 2010-09-30 | 2012-04-09 | 이정록 | 인쇄기능을 갖는 연질캡슐 제조장치 |
| US11793724B2 (en) * | 2018-08-16 | 2023-10-24 | Soo-Yeong Jung | Gelatin supply device for softgel encapsulation machine |
| WO2020066502A1 (ja) * | 2018-09-27 | 2020-04-02 | 芝浦メカトロニクス株式会社 | 錠剤印刷装置及び錠剤印刷方法 |
| WO2020185639A1 (en) * | 2019-03-08 | 2020-09-17 | Tri-Star Technologies | System and method for applying patterns on articles and inspection thereof |
| CA3069207C (en) * | 2019-05-01 | 2022-10-18 | Paul Lukas | Methods and systems for laser marking pharmaceutical capsules during manufacturing |
-
2020
- 2020-01-21 CA CA3069207A patent/CA3069207C/en active Active
- 2020-02-03 EP EP20155075.3A patent/EP3733148B1/en active Active
- 2020-02-03 ES ES20155075T patent/ES2982687T3/es active Active
- 2020-02-03 PL PL20155075.3T patent/PL3733148T3/pl unknown
- 2020-02-06 US US16/783,506 patent/US12214608B2/en active Active
- 2020-03-19 JP JP2020049555A patent/JP7241712B2/ja active Active
- 2020-03-20 KR KR1020200034190A patent/KR102564405B1/ko active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014534903A (ja) | 2011-09-16 | 2014-12-25 | トライスター テクノロジーズTristar Technologies | レーザカプセルマーキングシステムおよび方法 |
| US20170081069A1 (en) | 2011-09-16 | 2017-03-23 | Tri-Star Technologies | Laser Capsule Marking System and Method |
| JP2018001753A (ja) | 2016-06-28 | 2018-01-11 | 芝浦メカトロニクス株式会社 | 錠剤印刷装置及び錠剤印刷方法 |
| JP2019055177A (ja) | 2017-09-19 | 2019-04-11 | 芝浦メカトロニクス株式会社 | 錠剤印刷装置及び錠剤印刷方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP7241712B2 (ja) | 2023-03-17 |
| JP2020182828A (ja) | 2020-11-12 |
| CA3069207C (en) | 2022-10-18 |
| US20200346477A1 (en) | 2020-11-05 |
| KR20200127857A (ko) | 2020-11-11 |
| US12214608B2 (en) | 2025-02-04 |
| EP3733148A1 (en) | 2020-11-04 |
| CA3069207A1 (en) | 2020-11-01 |
| EP3733148B1 (en) | 2024-04-03 |
| PL3733148T3 (pl) | 2024-08-05 |
| ES2982687T3 (es) | 2024-10-17 |
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