KR102560207B1 - 아실 설폰아미드의 다형체 - Google Patents

아실 설폰아미드의 다형체 Download PDF

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Publication number
KR102560207B1
KR102560207B1 KR1020227029185A KR20227029185A KR102560207B1 KR 102560207 B1 KR102560207 B1 KR 102560207B1 KR 1020227029185 A KR1020227029185 A KR 1020227029185A KR 20227029185 A KR20227029185 A KR 20227029185A KR 102560207 B1 KR102560207 B1 KR 102560207B1
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South Korea
Prior art keywords
compound
formula
acid
delete delete
hiv
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KR1020227029185A
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English (en)
Korean (ko)
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KR20220120723A (ko
Inventor
제임스 프렌티스 데비드슨
마이클 마틴
페이 팡
마가렛 웡
Original Assignee
에프. 호프만-라 로슈 아게
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Priority to KR1020237025164A priority Critical patent/KR20230113420A/ko
Publication of KR20220120723A publication Critical patent/KR20220120723A/ko
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/51—Y being a hydrogen or a carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/42—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR1020227029185A 2008-09-09 2009-08-31 아실 설폰아미드의 다형체 Active KR102560207B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020237025164A KR20230113420A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9536408P 2008-09-09 2008-09-09
US61/095,364 2008-09-09
KR1020217027200A KR102437499B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
PCT/EP2009/061185 WO2010028968A2 (en) 2008-09-09 2009-08-31 Polymorphs of acyl sulfonamides

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020217027200A Division KR102437499B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020237025164A Division KR20230113420A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체

Publications (2)

Publication Number Publication Date
KR20220120723A KR20220120723A (ko) 2022-08-30
KR102560207B1 true KR102560207B1 (ko) 2023-07-27

Family

ID=41664548

Family Applications (7)

Application Number Title Priority Date Filing Date
KR1020177036902A Ceased KR20180001582A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020217027200A Active KR102437499B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020167020205A Active KR101822319B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020237025164A Ceased KR20230113420A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020187028288A Ceased KR20180110237A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020227029185A Active KR102560207B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020117005435A Active KR101678700B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체

Family Applications Before (5)

Application Number Title Priority Date Filing Date
KR1020177036902A Ceased KR20180001582A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020217027200A Active KR102437499B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020167020205A Active KR101822319B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020237025164A Ceased KR20230113420A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020187028288A Ceased KR20180110237A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020117005435A Active KR101678700B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체

Country Status (16)

Country Link
US (1) US8063103B2 (enExample)
EP (1) EP2334638B1 (enExample)
JP (6) JP5989339B2 (enExample)
KR (7) KR20180001582A (enExample)
CN (1) CN102143943B (enExample)
AU (1) AU2009290988B2 (enExample)
BR (3) BR122021020474B1 (enExample)
CA (5) CA3086566C (enExample)
EA (1) EA019340B1 (enExample)
ES (1) ES2706875T3 (enExample)
IL (4) IL299322B2 (enExample)
MX (1) MX2011002319A (enExample)
PL (1) PL2334638T3 (enExample)
TR (1) TR201818979T4 (enExample)
UA (1) UA107561C2 (enExample)
WO (1) WO2010028968A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2644156C1 (ru) 2017-02-28 2018-02-08 Александр Васильевич Иващенко Пролекарство ингибитора NS5B HCV полимеразы, способ его получения и применения
RU2665383C9 (ru) * 2017-06-22 2019-07-23 Общество с ограниченной ответственностью "Вириом" Фармацевтическая наносуспензия для терапии ВИЧ-инфекции
RU2662160C9 (ru) 2017-07-03 2018-10-22 Александрович Иващенко Андрей Комбинированный лекарственный препарат для терапии вирусных инфекций
RU2716257C1 (ru) * 2019-04-30 2020-03-11 Андрей Александрович Иващенко Активный компонент, фармацевтическая композиция и лекарственный препарат для терапии ВИЧ и СПИДа
RU2717101C1 (ru) 2019-06-03 2020-03-18 Андрей Александрович Иващенко Анелированные 9-гидрокси-1,8-диоксо-1,3,4,8-тетрагидро-2Н-пиридо[1,2-a]пиразин-7-карбоксамиды - ингибиторы интегразы ВИЧ, способы их получения и применения

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2272285C (en) * 1997-01-23 2006-11-21 Yamanouchi Pharmaceutical Co., Ltd. Amide derivatives and medicinal compositions thereof
US7625949B2 (en) * 2004-04-23 2009-12-01 Roche Palo Alto Llc Methods for treating retroviral infections
US7166738B2 (en) * 2004-04-23 2007-01-23 Roche Palo Alto Llc Non-nucleoside reverse transcriptase inhibitors
WO2005102989A1 (en) * 2004-04-23 2005-11-03 F. Hoffmann-La Roche Ag Non-nucleoside reverse transcriptase inhibitors
US7618981B2 (en) * 2004-05-06 2009-11-17 Cytokinetics, Inc. Imidazopyridinyl-benzamide anti-cancer agents
CN101166524B (zh) * 2005-04-28 2010-12-22 辉瑞有限公司 氨基酸衍生物
KR20080056220A (ko) * 2005-10-19 2008-06-20 에프. 호프만-라 로슈 아게 페닐-아세트아마이드 ｎｎｒｔ 저해제
KR20100092424A (ko) * 2007-07-30 2010-08-20 아디아 바이오사이언스즈 인크. 다형체를 포함하는, ｍｅｋ의 억제제로서의 ｎ-(아릴아미노) 술폰아미드의 유도체 및 조성물, 사용 방법 및 이의 제조 방법
JP2011514897A (ja) * 2008-03-04 2011-05-12 エフ．ホフマン−ラ ロシュ アーゲー 高濃度のミセル水溶液を調製する方法

Also Published As

Publication number Publication date
JP2021176894A (ja) 2021-11-11
BR122021020475B1 (pt) 2022-06-07
IL299322B1 (en) 2024-06-01
BR122021020474B1 (pt) 2022-06-07
US20100063154A1 (en) 2010-03-11
KR20110053234A (ko) 2011-05-19
KR20220120723A (ko) 2022-08-30
KR20180110237A (ko) 2018-10-08
CA3086566A1 (en) 2010-03-18
IL211353A0 (en) 2011-05-31
JP2019194229A (ja) 2019-11-07
IL299322B2 (en) 2024-10-01
EP2334638B1 (en) 2018-11-21
IL299322A (en) 2023-02-01
JP2012502075A (ja) 2012-01-26
JP2016172741A (ja) 2016-09-29
CA2949912C (en) 2019-12-03
CA3059552A1 (en) 2010-03-18
MX2011002319A (es) 2011-04-05
KR20230113420A (ko) 2023-07-28
KR101822319B1 (ko) 2018-01-25
KR102437499B1 (ko) 2022-08-29
JP2018058862A (ja) 2018-04-12
KR20210108499A (ko) 2021-09-02
KR20160092049A (ko) 2016-08-03
AU2009290988B2 (en) 2016-01-28
IL211353A (en) 2016-04-21
JP5989339B2 (ja) 2016-09-07
UA107561C2 (xx) 2015-01-26
CA3059552C (en) 2021-03-16
KR101678700B1 (ko) 2016-11-22
EA019340B1 (ru) 2014-02-28
AU2009290988A1 (en) 2010-03-18
WO2010028968A3 (en) 2010-06-10
KR20180001582A (ko) 2018-01-04
EA201100451A1 (ru) 2011-10-31
BRPI0918526B1 (pt) 2022-02-15
CA3003213A1 (en) 2010-03-18
US8063103B2 (en) 2011-11-22
BRPI0918526A2 (pt) 2015-12-01
WO2010028968A2 (en) 2010-03-18
ES2706875T3 (es) 2019-04-01
CA3003213C (en) 2021-07-20
EP2334638A2 (en) 2011-06-22
JP2023082131A (ja) 2023-06-13
CA2735192A1 (en) 2010-03-18
TR201818979T4 (tr) 2019-01-21
JP6450340B2 (ja) 2019-01-09
IL264118A (en) 2019-02-28
CA2735192C (en) 2017-02-28
IL244350A0 (en) 2016-05-01
CN102143943B (zh) 2014-03-12
PL2334638T3 (pl) 2019-04-30
CA2949912A1 (en) 2010-03-18
CN102143943A (zh) 2011-08-03
CA3086566C (en) 2025-09-02

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