IL299322B2 - Pharmaceutical composition of amorphous acyl sulfonamide - Google Patents

Pharmaceutical composition of amorphous acyl sulfonamide

Info

Publication number
IL299322B2
IL299322B2 IL299322A IL29932222A IL299322B2 IL 299322 B2 IL299322 B2 IL 299322B2 IL 299322 A IL299322 A IL 299322A IL 29932222 A IL29932222 A IL 29932222A IL 299322 B2 IL299322 B2 IL 299322B2
Authority
IL
Israel
Prior art keywords
compound
acid
hiv
space
administration
Prior art date
Application number
IL299322A
Other languages
English (en)
Hebrew (he)
Other versions
IL299322A (en
IL299322B1 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL299322A publication Critical patent/IL299322A/en
Publication of IL299322B1 publication Critical patent/IL299322B1/en
Publication of IL299322B2 publication Critical patent/IL299322B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/51—Y being a hydrogen or a carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/42—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
IL299322A 2008-09-09 2009-08-31 Pharmaceutical composition of amorphous acyl sulfonamide IL299322B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9536408P 2008-09-09 2008-09-09
PCT/EP2009/061185 WO2010028968A2 (en) 2008-09-09 2009-08-31 Polymorphs of acyl sulfonamides

Publications (3)

Publication Number Publication Date
IL299322A IL299322A (en) 2023-02-01
IL299322B1 IL299322B1 (en) 2024-06-01
IL299322B2 true IL299322B2 (en) 2024-10-01

Family

ID=41664548

Family Applications (4)

Application Number Title Priority Date Filing Date
IL299322A IL299322B2 (en) 2008-09-09 2009-08-31 Pharmaceutical composition of amorphous acyl sulfonamide
IL211353A IL211353A (en) 2008-09-09 2011-02-22 Polymorphs of sodium salt of acyl sulfonamides, processes for their preparation and pharmaceutical compositions comprising them
IL244350A IL244350A0 (en) 2008-09-09 2016-02-29 Pharmaceutical preparation of amorphous acyl sulfonamide
IL264118A IL264118A (en) 2008-09-09 2019-01-07 Pharmaceutical composition of amorphous acyl sulfonamide

Family Applications After (3)

Application Number Title Priority Date Filing Date
IL211353A IL211353A (en) 2008-09-09 2011-02-22 Polymorphs of sodium salt of acyl sulfonamides, processes for their preparation and pharmaceutical compositions comprising them
IL244350A IL244350A0 (en) 2008-09-09 2016-02-29 Pharmaceutical preparation of amorphous acyl sulfonamide
IL264118A IL264118A (en) 2008-09-09 2019-01-07 Pharmaceutical composition of amorphous acyl sulfonamide

Country Status (16)

Country Link
US (1) US8063103B2 (enExample)
EP (1) EP2334638B1 (enExample)
JP (6) JP5989339B2 (enExample)
KR (7) KR20230113420A (enExample)
CN (1) CN102143943B (enExample)
AU (1) AU2009290988B2 (enExample)
BR (3) BR122021020475B1 (enExample)
CA (5) CA2735192C (enExample)
EA (1) EA019340B1 (enExample)
ES (1) ES2706875T3 (enExample)
IL (4) IL299322B2 (enExample)
MX (1) MX2011002319A (enExample)
PL (1) PL2334638T3 (enExample)
TR (1) TR201818979T4 (enExample)
UA (1) UA107561C2 (enExample)
WO (1) WO2010028968A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2644156C1 (ru) 2017-02-28 2018-02-08 Александр Васильевич Иващенко Пролекарство ингибитора NS5B HCV полимеразы, способ его получения и применения
RU2665383C9 (ru) * 2017-06-22 2019-07-23 Общество с ограниченной ответственностью "Вириом" Фармацевтическая наносуспензия для терапии ВИЧ-инфекции
RU2662160C9 (ru) * 2017-07-03 2018-10-22 Александрович Иващенко Андрей Комбинированный лекарственный препарат для терапии вирусных инфекций
RU2716257C1 (ru) * 2019-04-30 2020-03-11 Андрей Александрович Иващенко Активный компонент, фармацевтическая композиция и лекарственный препарат для терапии ВИЧ и СПИДа
RU2717101C1 (ru) 2019-06-03 2020-03-18 Андрей Александрович Иващенко Анелированные 9-гидрокси-1,8-диоксо-1,3,4,8-тетрагидро-2Н-пиридо[1,2-a]пиразин-7-карбоксамиды - ингибиторы интегразы ВИЧ, способы их получения и применения

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050239881A1 (en) * 2004-04-23 2005-10-27 Roche Palo Alto Llc Non-nucleoside reverse transcriptase inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100519870B1 (ko) * 1997-01-23 2005-10-12 아스텔라스세이야쿠 가부시키가이샤 신규한 아미드 유도체 및 이를 함유하는 약제학적 조성물
US7625949B2 (en) 2004-04-23 2009-12-01 Roche Palo Alto Llc Methods for treating retroviral infections
AU2005235692B2 (en) * 2004-04-23 2011-11-10 F. Hoffmann-La Roche Ag Non-nucleoside reverse transcriptase inhibitors
US7618981B2 (en) * 2004-05-06 2009-11-17 Cytokinetics, Inc. Imidazopyridinyl-benzamide anti-cancer agents
EP1879567A1 (en) * 2005-04-28 2008-01-23 Pfizer Limited Amino acid derivatives
EP1940781A1 (en) * 2005-10-19 2008-07-09 F.Hoffmann-La Roche Ag Phenyl-acetamide nnrt inhibitors
CN103479604B (zh) * 2007-07-30 2016-08-10 阿迪生物科学公司 作为mek抑制剂的包括多晶型物的n-(芳氨基)磺酰胺衍生物和组合物、其使用方法和制备方法
CA2716082A1 (en) * 2008-03-04 2009-02-23 F. Hoffmann-La Roche Ag Process for preparing concentrated aqueous micellar solutions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050239881A1 (en) * 2004-04-23 2005-10-27 Roche Palo Alto Llc Non-nucleoside reverse transcriptase inhibitors

Also Published As

Publication number Publication date
JP6450340B2 (ja) 2019-01-09
BRPI0918526B1 (pt) 2022-02-15
EP2334638A2 (en) 2011-06-22
CN102143943A (zh) 2011-08-03
KR102560207B1 (ko) 2023-07-27
KR101678700B1 (ko) 2016-11-22
JP2021176894A (ja) 2021-11-11
IL244350A0 (en) 2016-05-01
CA3059552C (en) 2021-03-16
JP2019194229A (ja) 2019-11-07
CA3003213C (en) 2021-07-20
EP2334638B1 (en) 2018-11-21
KR20210108499A (ko) 2021-09-02
AU2009290988B2 (en) 2016-01-28
JP2023082131A (ja) 2023-06-13
IL211353A0 (en) 2011-05-31
KR20220120723A (ko) 2022-08-30
JP2018058862A (ja) 2018-04-12
IL264118A (en) 2019-02-28
WO2010028968A2 (en) 2010-03-18
CA2949912C (en) 2019-12-03
KR102437499B1 (ko) 2022-08-29
IL299322A (en) 2023-02-01
BR122021020475B1 (pt) 2022-06-07
JP2016172741A (ja) 2016-09-29
JP2012502075A (ja) 2012-01-26
WO2010028968A3 (en) 2010-06-10
CN102143943B (zh) 2014-03-12
JP5989339B2 (ja) 2016-09-07
AU2009290988A1 (en) 2010-03-18
IL211353A (en) 2016-04-21
CA2735192A1 (en) 2010-03-18
TR201818979T4 (tr) 2019-01-21
KR20160092049A (ko) 2016-08-03
PL2334638T3 (pl) 2019-04-30
CA3059552A1 (en) 2010-03-18
CA2735192C (en) 2017-02-28
KR101822319B1 (ko) 2018-01-25
US8063103B2 (en) 2011-11-22
BR122021020474B1 (pt) 2022-06-07
CA2949912A1 (en) 2010-03-18
ES2706875T3 (es) 2019-04-01
MX2011002319A (es) 2011-04-05
UA107561C2 (xx) 2015-01-26
US20100063154A1 (en) 2010-03-11
KR20180110237A (ko) 2018-10-08
KR20180001582A (ko) 2018-01-04
EA201100451A1 (ru) 2011-10-31
KR20110053234A (ko) 2011-05-19
CA3086566A1 (en) 2010-03-18
IL299322B1 (en) 2024-06-01
BRPI0918526A2 (pt) 2015-12-01
KR20230113420A (ko) 2023-07-28
CA3086566C (en) 2025-09-02
EA019340B1 (ru) 2014-02-28
CA3003213A1 (en) 2010-03-18

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