KR20180001582A - 아실 설폰아미드의 다형체 - Google Patents

아실 설폰아미드의 다형체 Download PDF

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Publication number
KR20180001582A
KR20180001582A KR1020177036902A KR20177036902A KR20180001582A KR 20180001582 A KR20180001582 A KR 20180001582A KR 1020177036902 A KR1020177036902 A KR 1020177036902A KR 20177036902 A KR20177036902 A KR 20177036902A KR 20180001582 A KR20180001582 A KR 20180001582A
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KR
South Korea
Prior art keywords
compound
formula
acid
hiv
polymorphic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020177036902A
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English (en)
Korean (ko)
Inventor
제임스 프렌티스 데비드슨
마이클 마틴
페이 팡
마가렛 웡
Original Assignee
에프. 호프만-라 로슈 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 에프. 호프만-라 로슈 아게 filed Critical 에프. 호프만-라 로슈 아게
Publication of KR20180001582A publication Critical patent/KR20180001582A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/51—Y being a hydrogen or a carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/42—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR1020177036902A 2008-09-09 2009-08-31 아실 설폰아미드의 다형체 Ceased KR20180001582A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9536408P 2008-09-09 2008-09-09
US61/095,364 2008-09-09
PCT/EP2009/061185 WO2010028968A2 (en) 2008-09-09 2009-08-31 Polymorphs of acyl sulfonamides

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020167020205A Division KR101822319B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020187028288A Division KR20180110237A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체

Publications (1)

Publication Number Publication Date
KR20180001582A true KR20180001582A (ko) 2018-01-04

Family

ID=41664548

Family Applications (7)

Application Number Title Priority Date Filing Date
KR1020227029185A Active KR102560207B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020177036902A Ceased KR20180001582A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020167020205A Active KR101822319B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020237025164A Ceased KR20230113420A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020117005435A Active KR101678700B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020217027200A Active KR102437499B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020187028288A Ceased KR20180110237A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1020227029185A Active KR102560207B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체

Family Applications After (5)

Application Number Title Priority Date Filing Date
KR1020167020205A Active KR101822319B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020237025164A Ceased KR20230113420A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020117005435A Active KR101678700B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020217027200A Active KR102437499B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020187028288A Ceased KR20180110237A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체

Country Status (16)

Country Link
US (1) US8063103B2 (enExample)
EP (1) EP2334638B1 (enExample)
JP (6) JP5989339B2 (enExample)
KR (7) KR102560207B1 (enExample)
CN (1) CN102143943B (enExample)
AU (1) AU2009290988B2 (enExample)
BR (3) BR122021020475B1 (enExample)
CA (5) CA3003213C (enExample)
EA (1) EA019340B1 (enExample)
ES (1) ES2706875T3 (enExample)
IL (4) IL299322B2 (enExample)
MX (1) MX2011002319A (enExample)
PL (1) PL2334638T3 (enExample)
TR (1) TR201818979T4 (enExample)
UA (1) UA107561C2 (enExample)
WO (1) WO2010028968A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2644156C1 (ru) 2017-02-28 2018-02-08 Александр Васильевич Иващенко Пролекарство ингибитора NS5B HCV полимеразы, способ его получения и применения
RU2665383C9 (ru) * 2017-06-22 2019-07-23 Общество с ограниченной ответственностью "Вириом" Фармацевтическая наносуспензия для терапии ВИЧ-инфекции
RU2662160C9 (ru) * 2017-07-03 2018-10-22 Александрович Иващенко Андрей Комбинированный лекарственный препарат для терапии вирусных инфекций
RU2716257C1 (ru) * 2019-04-30 2020-03-11 Андрей Александрович Иващенко Активный компонент, фармацевтическая композиция и лекарственный препарат для терапии ВИЧ и СПИДа
RU2717101C1 (ru) 2019-06-03 2020-03-18 Андрей Александрович Иващенко Анелированные 9-гидрокси-1,8-диоксо-1,3,4,8-тетрагидро-2Н-пиридо[1,2-a]пиразин-7-карбоксамиды - ингибиторы интегразы ВИЧ, способы их получения и применения

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2191177C2 (ru) * 1997-01-23 2002-10-20 Яманоути Фармасьютикал Ко., Лтд. Новые амидные производные и фармацевтическая композиция, промотирующая секрецию инсулина и усиливающая восприимчивость к инсулину
US7166738B2 (en) * 2004-04-23 2007-01-23 Roche Palo Alto Llc Non-nucleoside reverse transcriptase inhibitors
US7625949B2 (en) * 2004-04-23 2009-12-01 Roche Palo Alto Llc Methods for treating retroviral infections
JP4810529B2 (ja) * 2004-04-23 2011-11-09 エフ．ホフマン−ラ ロシュ アーゲー 非ヌクレオシド逆転写酵素インヒビター
US7618981B2 (en) * 2004-05-06 2009-11-17 Cytokinetics, Inc. Imidazopyridinyl-benzamide anti-cancer agents
BRPI0609879A2 (pt) * 2005-04-28 2010-05-11 Pfizer Ltd derivados de aminoácidos
KR20080056220A (ko) * 2005-10-19 2008-06-20 에프. 호프만-라 로슈 아게 페닐-아세트아마이드 ｎｎｒｔ 저해제
AU2008282338B2 (en) * 2007-07-30 2015-02-12 Ardea Biosciences, Inc. Derivatives of N-(arylamino) sulfonamides including polymorphs as inhibitors of MEK as well as compositions, methods of use and methods for preparing the same
CN101959502A (zh) * 2008-03-04 2011-01-26 弗·哈夫曼-拉罗切有限公司 制备浓缩胶束水溶液的方法

Also Published As

Publication number Publication date
IL299322A (en) 2023-02-01
JP6450340B2 (ja) 2019-01-09
BR122021020475B1 (pt) 2022-06-07
KR102560207B1 (ko) 2023-07-27
IL211353A (en) 2016-04-21
BR122021020474B1 (pt) 2022-06-07
JP2016172741A (ja) 2016-09-29
EP2334638A2 (en) 2011-06-22
UA107561C2 (xx) 2015-01-26
EA201100451A1 (ru) 2011-10-31
MX2011002319A (es) 2011-04-05
KR20210108499A (ko) 2021-09-02
CA3059552C (en) 2021-03-16
IL299322B2 (en) 2024-10-01
JP2023082131A (ja) 2023-06-13
CA3003213C (en) 2021-07-20
CA3086566C (en) 2025-09-02
WO2010028968A2 (en) 2010-03-18
PL2334638T3 (pl) 2019-04-30
JP2012502075A (ja) 2012-01-26
JP5989339B2 (ja) 2016-09-07
BRPI0918526A2 (pt) 2015-12-01
TR201818979T4 (tr) 2019-01-21
KR101822319B1 (ko) 2018-01-25
KR20180110237A (ko) 2018-10-08
CN102143943B (zh) 2014-03-12
CA2735192C (en) 2017-02-28
BRPI0918526B1 (pt) 2022-02-15
EP2334638B1 (en) 2018-11-21
CA3003213A1 (en) 2010-03-18
IL299322B1 (en) 2024-06-01
CA2735192A1 (en) 2010-03-18
CA2949912C (en) 2019-12-03
JP2021176894A (ja) 2021-11-11
AU2009290988B2 (en) 2016-01-28
ES2706875T3 (es) 2019-04-01
AU2009290988A1 (en) 2010-03-18
US20100063154A1 (en) 2010-03-11
KR102437499B1 (ko) 2022-08-29
JP2018058862A (ja) 2018-04-12
CA3059552A1 (en) 2010-03-18
WO2010028968A3 (en) 2010-06-10
CA3086566A1 (en) 2010-03-18
KR20160092049A (ko) 2016-08-03
KR20110053234A (ko) 2011-05-19
CA2949912A1 (en) 2010-03-18
JP2019194229A (ja) 2019-11-07
CN102143943A (zh) 2011-08-03
KR20220120723A (ko) 2022-08-30
IL264118A (en) 2019-02-28
KR20230113420A (ko) 2023-07-28
EA019340B1 (ru) 2014-02-28
KR101678700B1 (ko) 2016-11-22
IL244350A0 (en) 2016-05-01
US8063103B2 (en) 2011-11-22
IL211353A0 (en) 2011-05-31

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