CA3086566C - ACYLATE SULFONAMIDE POLYMORPHS - Google Patents

ACYLATE SULFONAMIDE POLYMORPHS

Info

Publication number
CA3086566C
CA3086566C CA3086566A CA3086566A CA3086566C CA 3086566 C CA3086566 C CA 3086566C CA 3086566 A CA3086566 A CA 3086566A CA 3086566 A CA3086566 A CA 3086566A CA 3086566 C CA3086566 C CA 3086566C
Authority
CA
Canada
Prior art keywords
compound
acid
hiv
date
polymorphic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3086566A
Other languages
English (en)
French (fr)
Other versions
CA3086566A1 (en
Inventor
James Prentice Davidson
Michael Martin
Fei Pang
Margaret Wong
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Priority to CA3086566A priority Critical patent/CA3086566C/en
Publication of CA3086566A1 publication Critical patent/CA3086566A1/en
Application granted granted Critical
Publication of CA3086566C publication Critical patent/CA3086566C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/51—Y being a hydrogen or a carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/42—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CA3086566A 2008-09-09 2009-08-31 ACYLATE SULFONAMIDE POLYMORPHS Active CA3086566C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA3086566A CA3086566C (en) 2008-09-09 2009-08-31 ACYLATE SULFONAMIDE POLYMORPHS

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9536408P 2008-09-09 2008-09-09
US61/095,364 2008-09-09
CA3059552A CA3059552C (en) 2008-09-09 2009-08-31 Polymorphs of acyl sulfonamides
CA3086566A CA3086566C (en) 2008-09-09 2009-08-31 ACYLATE SULFONAMIDE POLYMORPHS

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA3059552A Division CA3059552C (en) 2008-09-09 2009-08-31 Polymorphs of acyl sulfonamides

Publications (2)

Publication Number Publication Date
CA3086566A1 CA3086566A1 (en) 2010-03-18
CA3086566C true CA3086566C (en) 2025-09-02

Family

ID=41664548

Family Applications (5)

Application Number Title Priority Date Filing Date
CA3003213A Active CA3003213C (en) 2008-09-09 2009-08-31 Polymorphs of acyl sulfonamides
CA2949912A Active CA2949912C (en) 2008-09-09 2009-08-31 Polymorphs of acyl sulfonamides
CA3059552A Active CA3059552C (en) 2008-09-09 2009-08-31 Polymorphs of acyl sulfonamides
CA3086566A Active CA3086566C (en) 2008-09-09 2009-08-31 ACYLATE SULFONAMIDE POLYMORPHS
CA2735192A Active CA2735192C (en) 2008-09-09 2009-08-31 Polymorphs of acyl sulfonamides

Family Applications Before (3)

Application Number Title Priority Date Filing Date
CA3003213A Active CA3003213C (en) 2008-09-09 2009-08-31 Polymorphs of acyl sulfonamides
CA2949912A Active CA2949912C (en) 2008-09-09 2009-08-31 Polymorphs of acyl sulfonamides
CA3059552A Active CA3059552C (en) 2008-09-09 2009-08-31 Polymorphs of acyl sulfonamides

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2735192A Active CA2735192C (en) 2008-09-09 2009-08-31 Polymorphs of acyl sulfonamides

Country Status (16)

Country Link
US (1) US8063103B2 (enExample)
EP (1) EP2334638B1 (enExample)
JP (6) JP5989339B2 (enExample)
KR (7) KR102560207B1 (enExample)
CN (1) CN102143943B (enExample)
AU (1) AU2009290988B2 (enExample)
BR (3) BR122021020475B1 (enExample)
CA (5) CA3003213C (enExample)
EA (1) EA019340B1 (enExample)
ES (1) ES2706875T3 (enExample)
IL (4) IL299322B2 (enExample)
MX (1) MX2011002319A (enExample)
PL (1) PL2334638T3 (enExample)
TR (1) TR201818979T4 (enExample)
UA (1) UA107561C2 (enExample)
WO (1) WO2010028968A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2644156C1 (ru) 2017-02-28 2018-02-08 Александр Васильевич Иващенко Пролекарство ингибитора NS5B HCV полимеразы, способ его получения и применения
RU2665383C9 (ru) * 2017-06-22 2019-07-23 Общество с ограниченной ответственностью "Вириом" Фармацевтическая наносуспензия для терапии ВИЧ-инфекции
RU2662160C9 (ru) * 2017-07-03 2018-10-22 Александрович Иващенко Андрей Комбинированный лекарственный препарат для терапии вирусных инфекций
RU2716257C1 (ru) * 2019-04-30 2020-03-11 Андрей Александрович Иващенко Активный компонент, фармацевтическая композиция и лекарственный препарат для терапии ВИЧ и СПИДа
RU2717101C1 (ru) 2019-06-03 2020-03-18 Андрей Александрович Иващенко Анелированные 9-гидрокси-1,8-диоксо-1,3,4,8-тетрагидро-2Н-пиридо[1,2-a]пиразин-7-карбоксамиды - ингибиторы интегразы ВИЧ, способы их получения и применения

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2191177C2 (ru) * 1997-01-23 2002-10-20 Яманоути Фармасьютикал Ко., Лтд. Новые амидные производные и фармацевтическая композиция, промотирующая секрецию инсулина и усиливающая восприимчивость к инсулину
US7166738B2 (en) * 2004-04-23 2007-01-23 Roche Palo Alto Llc Non-nucleoside reverse transcriptase inhibitors
US7625949B2 (en) * 2004-04-23 2009-12-01 Roche Palo Alto Llc Methods for treating retroviral infections
JP4810529B2 (ja) * 2004-04-23 2011-11-09 エフ．ホフマン−ラ ロシュ アーゲー 非ヌクレオシド逆転写酵素インヒビター
US7618981B2 (en) * 2004-05-06 2009-11-17 Cytokinetics, Inc. Imidazopyridinyl-benzamide anti-cancer agents
BRPI0609879A2 (pt) * 2005-04-28 2010-05-11 Pfizer Ltd derivados de aminoácidos
KR20080056220A (ko) * 2005-10-19 2008-06-20 에프. 호프만-라 로슈 아게 페닐-아세트아마이드 ｎｎｒｔ 저해제
AU2008282338B2 (en) * 2007-07-30 2015-02-12 Ardea Biosciences, Inc. Derivatives of N-(arylamino) sulfonamides including polymorphs as inhibitors of MEK as well as compositions, methods of use and methods for preparing the same
CN101959502A (zh) * 2008-03-04 2011-01-26 弗·哈夫曼-拉罗切有限公司 制备浓缩胶束水溶液的方法

Also Published As

Publication number Publication date
IL299322A (en) 2023-02-01
JP6450340B2 (ja) 2019-01-09
BR122021020475B1 (pt) 2022-06-07
KR102560207B1 (ko) 2023-07-27
IL211353A (en) 2016-04-21
BR122021020474B1 (pt) 2022-06-07
JP2016172741A (ja) 2016-09-29
EP2334638A2 (en) 2011-06-22
UA107561C2 (xx) 2015-01-26
EA201100451A1 (ru) 2011-10-31
MX2011002319A (es) 2011-04-05
KR20210108499A (ko) 2021-09-02
CA3059552C (en) 2021-03-16
IL299322B2 (en) 2024-10-01
JP2023082131A (ja) 2023-06-13
CA3003213C (en) 2021-07-20
WO2010028968A2 (en) 2010-03-18
PL2334638T3 (pl) 2019-04-30
JP2012502075A (ja) 2012-01-26
JP5989339B2 (ja) 2016-09-07
BRPI0918526A2 (pt) 2015-12-01
TR201818979T4 (tr) 2019-01-21
KR101822319B1 (ko) 2018-01-25
KR20180110237A (ko) 2018-10-08
CN102143943B (zh) 2014-03-12
CA2735192C (en) 2017-02-28
BRPI0918526B1 (pt) 2022-02-15
EP2334638B1 (en) 2018-11-21
CA3003213A1 (en) 2010-03-18
IL299322B1 (en) 2024-06-01
CA2735192A1 (en) 2010-03-18
KR20180001582A (ko) 2018-01-04
CA2949912C (en) 2019-12-03
JP2021176894A (ja) 2021-11-11
AU2009290988B2 (en) 2016-01-28
ES2706875T3 (es) 2019-04-01
AU2009290988A1 (en) 2010-03-18
US20100063154A1 (en) 2010-03-11
KR102437499B1 (ko) 2022-08-29
JP2018058862A (ja) 2018-04-12
CA3059552A1 (en) 2010-03-18
WO2010028968A3 (en) 2010-06-10
CA3086566A1 (en) 2010-03-18
KR20160092049A (ko) 2016-08-03
KR20110053234A (ko) 2011-05-19
CA2949912A1 (en) 2010-03-18
JP2019194229A (ja) 2019-11-07
CN102143943A (zh) 2011-08-03
KR20220120723A (ko) 2022-08-30
IL264118A (en) 2019-02-28
KR20230113420A (ko) 2023-07-28
EA019340B1 (ru) 2014-02-28
KR101678700B1 (ko) 2016-11-22
IL244350A0 (en) 2016-05-01
US8063103B2 (en) 2011-11-22
IL211353A0 (en) 2011-05-31

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