KR102556188B1 - Moxa cautery concentrate cake pas and process for preparing the same - Google Patents

Abstract

The present invention relates to a patch containing mugwort extract as an active ingredient and a method for manufacturing the same, and more particularly, to mugwort that has a high active ingredient content and does not generate smoke during extraction, which can provide an eco-friendly solution. It relates to essence gopas and its preparation method. According to the present invention, 100% of the active ingredients of mugwort condensed from the smoke generated during the production of mugwort concentrate into solids are condensed to form a paste, which can be preferably used.

Description

Moxa cautery concentrate cake pas and process for preparing the same}

The present invention relates to a patch containing mugwort extract as an active ingredient and a method for manufacturing the same, and more particularly, to mugwort that has a high active ingredient content and does not generate smoke during extraction, which can provide an eco-friendly solution. It relates to essence gopas and its preparation method.

In general, treatment through moxibustion is an oriental medicine treatment that corrects abnormalities in the body by burning herbs such as mugwort on a specific part of the skin. contributing to prevention and treatment.

This moxibustion treatment has been mainly performed by placing moxibustion directly on the skin and burning it to cause small burns, but this method may cause side effects such as burns after the procedure.

There are direct and indirect types of moxibustion, and direct moxibustion is a method of burning mugwort directly on the skin and moxibustion. The indirect method is to put a mugwort model on a mugwort moxibustion device, burn mugwort, and some of the mugwort smoke comes down to the skin and is applied to the skin. As the heat of burning mugwort is transferred to the skin, it is moxibusted. It is difficult to moxibustion in a crowded space because it emits a lot of smoke and smells bad. The moxibustion time is short and the efficiency is low.

These conventional techniques are less reliable in their efficacy, and in particular, it has been shown to have a great effect on the prevention and treatment of diseases according to the formulation of the moxibustion composition.

Therefore, there is a demand for mugwort extract products or treatment methods using them that do not reduce skin wounds or generate smoke around them.

Korean Registration No. 10-0353613 (September 9, 2002) Korean Registration No. 10-1353478 (January 14, 2014) Korea Registration No. 10-1834794 (February 27, 2018)

As a result of intensive research in order to improve the problems of the prior art as described above and to develop a method for doubling the therapeutic effect of mugwort extract, the present inventors found mugwort extract obtained using an extractor as an active ingredient as described below. It was found that the containing paste can be used safely and efficiently and came to complete the present invention.

Accordingly, an object of the present invention is to provide a mugwort extract gopa containing mugwort extract as an active ingredient and a method for preparing the same.

The purpose of the present invention as above is

an upper impermeable support layer (10);

a drug delivery layer (20) containing mugwort extract located below the support layer (10) as an active ingredient;

A controlled-release adhesive layer 30 located below the drug delivery layer 20 and in contact with the skin, and

A release layer 40 attached to the back surface of the adhesive layer 30 and peeled off during use;

The drug delivery layer (20) contains 20 to 40 parts by weight of mugwort extract, 50 to 60 parts by weight of a water-soluble polymer solvent for matrix formation, and 2 to 10 parts by weight of a skin penetration enhancer. can be achieved by

According to the present invention, 100% of the active ingredients of mugwort condensed from the smoke generated during the production of mugwort concentrate into solids are condensed to form a paste, which can be preferably used.

1 is a diagram illustrating the layer structure of mugwort extract gopas according to the present invention. Figure 2 is a process chart for manufacturing mugwort concentrate gopas according to the present invention. Figure 3 is an explanatory diagram of a condensation device according to the present invention Figure 4 is a photographic explanatory view of a condensing device according to the present invention Figure 5 is a left and right photo explanatory view of the condensing device according to the present invention Figure 6 is a picture of the inside of the condensing chamber of the condensing device according to the present invention 7 is a view for explaining the structure of a condensing chamber of the condensing device according to the present invention. FIG. 8 is a view explaining the arrangement structure of the condensing device according to the present invention. FIG. 10 is a view explaining the structure of a humidifier of a condensing device according to the present invention. FIG. 11 is an explanatory view of a dustproof member of the condensing device according to the present invention.

The present invention, in one aspect,

an upper impermeable support layer (10);

a drug delivery layer (20) containing mugwort extract located below the support layer (10) as an active ingredient;

A controlled-release adhesive layer 30 located below the drug delivery layer 20 and in contact with the skin, and

A release layer 140 attached to the back surface of the adhesive layer 30 and peeled off during use;

The drug delivery layer 120 is a mugwort essence gopas, characterized in that it contains 20 to 40 parts by weight of mugwort extract, 50 to 60 parts by weight of a water-soluble polymer solvent for matrix formation, and 2 to 10 parts by weight of a skin penetration enhancer to provide.

The present invention, in a further aspect,

The above mugwort essence extract

(a) pre-treating mugwort to remove foreign substances;

(b) drying the pretreated mugwort;

(c) crushing the dried mugwort;

(d) putting the extracted mugwort into a combustion chamber and burning it;

(e) condensing the smoke produced by the combustion process;

(f) recovering condensed solids;

(g) blending additives into the recovered condensate; and

(h) packaging the blended condensate; provides a mugwort essence gopas, characterized in that it is produced by a method for producing mugwort paste, including.

According to the present invention, the smoke from burning mugwort is condensed and made into a ball, applied to the affected area, diseased, or painful area, heated with a constant heat in a near-infrared bioceramic heater, and irradiated with mugwort components and near-infrared heat to the application site, pushing into the bone marrow and improving muscle blood vessels Moxa can be moxa for a lot of time freely by expanding the cells in the affected area to supply nutrients, immunity, lymph fluid, etc. It can be used to prepare various formulations.

In another aspect of the present invention,

The mugwort concentrate first mixes the active ingredient containing the mugwort extract with a water-soluble polymer solvent and a skin permeation enhancer for matrix formation to form a drug delivery layer 20, and then applies it on the support 10, 40 It provides mugwort essence gopas, which is characterized in that it is prepared by drying at ~80 ° C. to form an active ingredient supporting layer, and then laminating the adhesive layer 30 and the release layer 40.

In another aspect of the present invention,

The support layer 10 is made of a polyurethane or polyethylene film, and the release-controlled adhesive layer 30 includes 80 to 95 parts by weight of a polyacrylate block copolymer, 1 to 10 parts by weight of a water-soluble polymer, and a skin penetration enhancer. It is composed of 2 to 10 parts by weight, and the release layer 40 provides a mugwort essence high paste, characterized in that it is made of a polyester film.

In order to solve the problems associated with direct and indirect injection, the present inventor condenses the smoke by burning mugwort to make a go, and applies it to the moxibustion area of the sore and painful area, and irradiates at a distance of 35 to 50 cm at a temperature suitable for the patient's condition with a ceramic heater It was confirmed that the beneficial components of mugwort and the near-infrared rays of the ceramic heater penetrated through the skin to the bone marrow, and the disease that entered the shooting range was cured as it was. As a result, it was found that it can be applied safely and efficiently.

Hereinafter, the method for manufacturing mugwort extract gopas according to the present invention will be described in more detail with reference to the accompanying drawings and specific examples.

The terms or words used in this specification and claims are not limited to the usual or dictionary meanings, and the inventor can properly define the concept of the term in order to explain his or her invention in the best way. Based on this, it should be interpreted as a meaning and concept consistent with the technical spirit of the present invention. Therefore, since the embodiments described in this specification and the configurations shown in the drawings are only the most preferred embodiments of the present invention, it is understood that there may be various equivalents and modifications that can replace them at the time of this application. shall.

In addition, in order to more easily explain the present invention, normal valves and pipes are arbitrarily omitted, but these valves and pipes constitute the present invention even if not explicitly described as self-evident when viewed from the level of experts in the technical field of the present invention. As part of a conventional device that can be included in the components of the present invention.

As shown in FIG. 1, the mugwort extract Gopa according to the present invention includes an upper impermeable support layer 10; a drug delivery layer (20) containing mugwort extract located below the support layer (10) as an active ingredient; A controlled-release adhesive layer 30 located below the drug delivery layer 20 and in contact with the skin, and a release layer 40 attached to the back surface of the adhesive layer 30 and peeled off during use; may be made including .

Mugwort essence and paste according to the present invention first mixes active ingredients including mugwort essence with a water-soluble polymer solvent and skin permeation promoter for matrix formation to form a drug delivery layer (20), and then apply it on the support (10) And, it can be prepared by drying at 40 ~ 80 ℃ to form an active ingredient supporting layer, and then laminating the adhesive layer 30 and the release layer (40).

The support layer 10 is made of a material that is impermeable to drugs and has good moisture permeability and elasticity. For example, a polyurethane or polyethylene film may be used.

The drug delivery layer 20 and the controlled-release adhesive layer 30 may be combined into one layer.

The drug delivery layer 20 may preferably include 20 to 40 parts by weight of mugwort extract, 50 to 60 parts by weight of a water-soluble polymer solvent for matrix formation, and 2 to 10 parts by weight of a skin penetration enhancer.

The active ingredient, mugwort extract, can be preferably prepared as described below.

The polymer solvent for forming the matrix is used to form the matrix of the active ingredient supporting layer, preferably a group consisting of polydimethyloxane, acrylate, methacrylate, polyisobutylene, and styrene-isoprene-styrene One or more of these are used.

In addition, the polymer solvent for forming the matrix is preferably included in an amount of 50 to 60 parts by weight based on the total weight of the active ingredient carrying layer solution. If it exceeds this value, active ingredients may not penetrate well, and if it is less than this value, it is difficult to exert sufficient supporting function.

The skin permeation enhancer is used to control the permeation rate of the active ingredient, preferably N-cyclohexyl-2-pyrrolidone, 1-butyl-3-dodecyl- 2-pyrrolidone (1-butyl-3-dodecyl-2-pyrrolidone), 1,5-dimethyl-2-pyrrolidone (1,5-dimethyl-2-pyrrolidone), 1-ethyl-2-pyrrolidone Money (1-ethyl-2-pyrrolidone), 1-hexyl-4-methyloxycarbonyl-2-pyrrolidone (1-hexyl4-methyloxycarbonyl-2-pyrrolidone), 1-hexyl-2-pyrrolidone (1 -hexyl-2-pyrrolidone), 1-(2-hydroxyethyl)pyrrolidone (1-(2-hydroxyethyl)pyrrolidone), 3-hydroxy-N-methyl-2-pyrrolidone (3-hydroxy- N-methyl-2-pyrrolidone), N-methyl-2-pyrrolidone, N-caprylyl-2-pyrrolidone, glycerol Glycerol lauryl alcohol, oleylalcohol, isopropyl myristrate, sorbitan mono-oleate, propylene monolaurate, propylene mono-oleate (propylene mono-oleate), oleyl macrogolglyceride, oleic acid, lauroyl macrogoglyceride, linoleoyl macrogoglyceride, propylene glycol Propylene glycol caprylate/caprate, Sorbitan monostearate mono-oleate, glycerol monolaurate, propylene glycol monolaurate , propylene glycol monocaprylate, sorbitan monolaurate, lauryl lactate, caprylic/capric triglyceride, corn oil PEG- 8 ester, corn oil PEG-6 ester, triacetin, fatty alcohol, sorbitan monooleate, n,n-diethyl-m-toluamide, myristic acid, N-methyl-2-pyrrolidone and cine It can be added by selecting from all.

In addition, it may be desirable to contain a solvent that can also be used as a permeation enhancer. A solvent suitable for this is diethylol, which has excellent drug solubility and high boiling point, which is not easily volatilized during drying after coating. It is preferable to use ruamide, dimethylformamide, dimethyl sulfoxide or the like.

In addition, the skin permeation enhancer is preferably 2 to 10 parts by weight based on the total weight of the active ingredient carrying layer solution in order to minimize skin side effects.

The controlled-release adhesive layer 30 may preferably be made of 80 to 95 parts by weight of a polyacrylate block copolymer, 1 to 10 parts by weight of a water-soluble polymer, and 2 to 10 parts by weight of a skin penetration enhancer.

In addition, the release-controlling adhesive layer 30 is made of an adhesive component, preferably one or two or more selected from the group consisting of a functional group consisting of -COOH, -OH or -NH ₂ functional groups are used as an acrylic pressure-sensitive adhesive, Preferably, as the polyacrylate block copolymer, acrylic acid, 2-ethylhexyl acrylate, butyl acrylate, 2-hydroxyethyl acrylate, methyl methacrylate, methyl acrylate, glycidyl methacrylate, vinyl acetate, One or two or more pressure-sensitive adhesives from the group consisting of N-vinyl-2pyrrolidone, diacetone acrylamide, t-octyl acrylamide, and 2-(dimethylaminoethyl) methacrylate may be used in combination.

The content of the pressure-sensitive adhesive is preferably 80 to 95 parts by weight based on the total weight of the controlled-release adhesive layer.

The release-controlling adhesive layer 30 is characterized in that it contains a water-soluble polymer in order to prevent the release of the formulation from the skin due to the release of excessive sweat and to control the absorption of the active ingredient into the skin while keeping the active ingredient-bearing layer in close contact with the skin. to be

The water-soluble polymer is preferably hydroxyethylcellulose, ethylcellulose polymers, polyvinylpyridolidone (PVP), polyethylene oxide (PEO), polyethylene glycol (PEG), polyacrylic acid (PAA), At least one selected from the group consisting of hydroxylpropylcellulose (HPC), pullulan, gelatin, pectin, alginic acid, sodium alginate, carrageenan, gum arabic, guar gum, locust bean gum, xanthan gum, gellan gum and agar is used desirable.

The water-soluble polymer is preferably within 1 to 10 parts by weight based on the total weight of the release-modifying adhesive layer.

On the other hand, the release-controlling adhesive layer 30 may further include mineral-coated microparticles to increase the surface area of the adhesive layer in contact with the skin and to deliver active ingredients to the skin through void formation. A suitable microparticle size is preferably in the range of 1 μm to 10 μm in diameter, and the content of the microparticles is preferably 1 to 10 parts by weight based on the total weight of the release-modifying adhesive layer.

The release layer 40 may use a polyester film.

The thicknesses of the support layer 10 and the release layer 40 are suitably 40 to 300 μm and 10 to 40 μm, respectively. If the thickness of each layer is out of the above range, it is not preferable because appropriate flexibility is lost and adhesive strength is reduced when applied to the skin of a curved part.

The above mugwort essence extract

(a) pre-treating mugwort to remove foreign substances;

(b) drying the pretreated mugwort;

(c) crushing the dried mugwort;

(d) putting the extracted mugwort into a combustion chamber and burning it;

(e) condensing the smoke produced by the combustion process;

(f) recovering condensed solids;

(g) blending additives into the recovered condensate; and

(h) packaging the blended condensate; can be produced by a method for producing mugwort containing.

The present invention provides a method of obtaining condensation while absorbing smoke burned in a combustion chamber, and the vapor obtained by condensing smoke burned in a combustion chamber contains 100% of mugwort components as they are. However, in the usual way, for example, by boiling mugwort to obtain goo, the potency of mugwort evaporates during boiling, and the leftover residue has little medicinal effect.

Figure 2 is a process diagram for the production of mugwort concentrate according to the present invention, Figure 3 is an explanatory view of the condensing apparatus according to the present invention, Figure 4 is a photographic perspective explanatory view of the condensing apparatus according to the present invention, Figure 5 is Left and right photo explanatory diagrams of the condensing device according to the present invention, Figure 6 is a photo explanatory view of the inside of the condensing chamber of the condensing device according to the present invention, Figure 7 explains the structure of the condensing chamber of the condensing device according to the present invention Figure 8 is a view for explaining the arrangement structure of the condensing device according to the present invention, Figure 9 is a view explaining the arrangement structure of the outside air inlet, Figure 10 is a view explaining the structure of the humidifier of the condensing device according to the present invention 11 is an explanatory view of the anti-vibration member of the condensing device according to the present invention.

As shown in FIG. 2, the method for manufacturing mugwort extract according to an embodiment of the present invention includes a pretreatment step, a drying step, a powder (crushing) step, a combustion step, a condensation step, a recovery step, an additive blending step, and a packaging step. It is done. Each step is described in detail below.

(a) pretreatment step

In the pretreatment step, it is a step of selecting mugwort to remove foreign substances, and it may be more preferable that the obtained mugwort material is grown with eco-friendly pesticides.

Washing the mugwort may cause the effective ingredients of the mugwort to escape, so washing needs to be omitted as much as possible.

(b) drying step

Then, in the drying step, the mugwort is naturally dried or dried using a dryer.

In the case of natural drying, for example, spread mugwort widely to a thickness of 1 to 2 cm in a well-ventilated room, place it on a shelf or net, and turn it over intermittently for 12 to 30 hours at room temperature to dry it so that moisture evaporates evenly. It is better to leave it in an appropriately oxidized state.

On the other hand, the drying time when drying under direct sunlight is 0.2 to 1 hour or longer, preferably 0.5 to 1 hour or longer depending on the amount of sunlight.

In the drying step, it may be preferable to dry the material so that the water content is 50 to 65% (w/w).

(c) follow-up stage

The dried mugwort is crushed (crushed) to a certain size (eg, 10 to 50 mesh).

(d) combustion phase

It may be desirable to put the dried mugwort tightly into the mugwort combustion chamber 110 of the combustion device 100 as shown in FIG. 3 and burn it.

The combustion device 100 includes an upper combustion chamber 110, a mugwort box filter 120 located below the combustion chamber 110, a mugwort smoke purification chamber 130 located below the mugwort box filter 120, the The mugwort smoke purification chamber box 140 located below the mugwort smoke purification chamber 130 may be arranged vertically.

The combustion chamber 110 is provided with a separate ignition device (not shown) to ignite the dried mugwort, a damper 111-1 is installed in the air passage so that air can be supplied to the top, and an oxygen supply unit ( 111) is provided to control the combustion state of mugwort. When the ignition is turned on, the surface of the mugwort burns and smoke is generated.

Since a lot of mugwort is put in the combustion chamber 110, it may not burn and the fire may go out, so that a high-purity condenser can be obtained by completely burning it with the circuit configuration of the damper 111-1 and the oxygen supply unit 111.

In addition, the combustion chamber 110 has a handle on the side, an opening and closing door (not shown) and a double support (wormwood box filter 120 and mugwort purification filter 121) for recovering ash after burning mugwort at the bottom. By doing so, it is possible to clean the inside of the combustion chamber 110 and the like.

The mugwort box filter 120 is located in the lower part of the combustion chamber 110 so that smoke can pass through, so that solids after burning mugwort do not pass through.

A guide pipe 150 is installed in communication with the upper side of the mugwort smoke purification chamber 130, and a canvas 151 is provided inside the guide pipe 150. In addition, a smoke guide plate 131, which is a fine mesh, is inclined on the upper inclined plate of the air purification chamber 130 to allow only smoke to pass through, and impurities including fine ash fall freely while precipitating in water and being drained.

The smoke passing through the mugwort box filter 120 is moved to the condensation chamber 200 through the canvas 151 installed inside the guide tube 150 disposed on the upper side of the mugwort smoke purification chamber 130.

On the other hand, a mugwort smoke purification chamber box 140 is installed at the lower part of the mugwort smoke purification chamber 130, and an external water supply pipe 141 is connected to the upper part of the mugwort smoke purification chamber box 140 to periodically or intermittently water It can be supplied to the drain box 140.

Therefore, impurities including ash that have passed through the filter box 120 fall freely and are precipitated in the water supplied by the water supply pipe 141 and discharged to the outside through the drain hole 142 of the mugwort smoke purification chamber box 140. .

(e)(f) condensation and recovery steps

The smoke of the burnt mugwort flows into the condensing device 200 through the guide pipe 150 by the operation of the canvas 151.

The condensing step (e) is characterized in that the generated smoke is condensed into a solid state by a condensing unit equipped with condensing plates 211 and 212 provided inside the condensing device 200.

Referring to the drawings, the condensing device 200 of the present invention includes a housing 210 formed in a hexahedral shape, a viewing window 220 provided on one side of the housing 210, and a A thermometer 230 and an automatic temperature sensor 231, a humidity sensor 241 provided at the bottom of the discharge of non-condensable gas, condensation plates 211 and 212 repeatedly and regularly arranged inside the housing 210, the housing ( 210), a vibrator 250 attached to both sides of the outer lower part, one or more condensation storage recovery ports 260 provided on the lower part of the housing 210, a plurality of anti-vibration springs 295 attached to the bottom of the housing 210, It includes a non-condensing gas pipe 270 installed in communication with the rear end of the housing 210, a damper 280 and a blower 290 sequentially installed inside the outlet side of the non-condensing gas pipe 270, the housing (210) is characterized in that it is disposed inclined at a certain angle.

One side of the housing 210 is installed in communication with the guide pipe 150 installed on the upper side of the mugwort smoke purification chamber 130.

Since the housing 210 is inclined at a certain angle (eg, 25° is most preferable), condensate recovery efficiency can be increased.

The housing 210 has a hexahedral shape and its interior is partitioned by two or more partition walls.

The viewing window 220 is provided on one side of the housing 210 to observe the circulation state and condensation state of the smoke.

A support frame (SF) is provided on the lower side and bottom of the condensation chamber 200 to support the condensation chamber 200 .

The thermometer 230 is provided at the top center of the condensation chamber 200, the automatic temperature sensor 231 is located at the top center of the condensation chamber 200, and sensors for controlling temperature and humidity (231, 241) ) can increase the condensation efficiency by raising and lowering the temperature and humidity according to the control signal of the control panel 300 according to the condensation state of the smoke. The mugwort smoke enters the condensation chamber and undergoes a condensation process by mixing the humidified water vapor and the mugwort smoke.

As shown in FIG. 9, the vapor type humidifier 160 is provided on the lower side of one side of the condensing device, two or more heaters H are built in an independent housing, and a hygrometer M and a thermometer T are located at the top A general structure in which a water inlet (WI) is provided on the upper left side, a drain hole (D) is provided on the lower side, and a temperature sensor (TS) is provided on the lower left side, by the control panel 300 or by a separate operation It can be operated by means, and the generated moisture can be supplied to the humidity sensor 241 in the form of steam to adjust the humidity.

Mugwort smoke and humidified steam are mixed according to the internal temperature conditions, and the amount of outdoor air inflow can be controlled through the automatic temperature sensor 231, humidity sensor 241, and outdoor air inlet 245 that can control the condensation temperature, and the outdoor air inlet (245 ) is composed of a heater 247, a blower 248, and a damper 249, and when the temperature of the device becomes too cold, heat is applied to the heater to adjust the constant temperature and humidity circuit configuration. .

An outdoor air inlet 245 is provided on the bottom surface of the housing 210 on the smoke inlet side to allow air to flow into the condensing device 200 and condensate the smoke well.

The condensation plates 211 and 212 are repeatedly and regularly arranged inside the housing 210, the plate 211 based on the central partition wall is attached to the side, and the other plate 212 is repeatedly attached to the central partition wall. Attached, the end is formed with a space through which smoke passes, so that the smoke passing through the guide tube 150 of the mugwort smoke purification chamber 130 passes through the space formed at the ends of the condensation plates 211 and 212 The condensation process proceeds in

The material of the condensation plates 211 and 212 may be preferably SUS stainless 304.

One or more (four) vibrators 250 are attached to both sides of the housing 210 so that the condensed condensate more easily flows to the condensed condensate collection port 260.

One or more condensation storage outlets 260 are provided on both side surfaces of the housing 210 and are transported so that the condensation storage flows smoothly by vibration caused by the operation of the vibrator 250 . Reference numeral 246 denotes a recovery passage of the condensation chamber. To this end, the bottom surface of the condensation chamber has a structure in which a certain shape of the condensation chamber is through-holes between the partition walls in order to recover the condensation pool.

A plurality of (six or more) anti-vibration springs 295 are attached to the bottom of the housing 210 to absorb the vibration of the vibrator 250 from the ground.

On the other hand, the non-condensing gas pipe 270 is installed at the rear end of the housing 210 to communicate with the inside, and the installation height is preferably slightly higher than the bottom.

A damper 280 and a blower 290 are sequentially included inside the outlet side of the non-condensing gas pipe 270, and some of the non-condensing non-condensing gas is mixed with external air to be re-supplied or discharged to the outside do.

The control panel 300 includes a control board and controls the overall operation and functions of the device. Of course, the automatic temperature sensor 231 and humidity sensor 241 are controlled, the air supply and intake amount are controlled, the canvas 151 blocks the vibration generated from the condensing device from being transmitted to the combustion chamber, and the ignition device and oxygen supply unit 111, the air damper 111-1, the vibrator 250, the air amount of the outside air inlet 245, and the operation of the damper 280 and the blower 290 are controlled.

The control panel 300 of the present invention for performing the above operation is provided with an input unit and a display unit, and a storage unit for storing set information previously input by the user through the input unit, that is, temperature and operating time, air supply amount, and the like. Extraction conditions can be controlled based on set information.

To explain the manufacturing process of mugwort smoke using the above-mentioned device, first, after inputting the necessary extraction information through the control panel 300, open the air damper 111-1 and inject the dried mugwort into the air damper 111-1. 1) is closed, then the combustion process is started, and air necessary for combustion is supplied through the oxygen supply means 111. As the humidification starts, the mugwort smoke and the humidified water vapor are mixed and circulated through the condensation plates 211 and 212 and collided with a narrow wall to be condensed. If the condensed mugwort smoke and moisture are too thin, the vibration of the vibrator (250) helps the mugwort smoke to condense well by strong impact and collision on the plate as it flows down through the condensation plate by adjusting the humidification, and the recovery port (260 ), the condensate is collected by flowing down the slope so that the condensate can be well recovered.

In addition, additional necessary medicines can be added at the rate of Gunsinjwasa and burned with mugwort. At this time, mugwort belongs to group (君), and according to the prescription of the disease, it can produce goo in the prescription at the weight ratio of gunshin jwasa (10: 7: 5: 3). Among the necessary medicines, frankincense, myrrh, cinnamon tree, balsam seed, and lacquer belong to the gods, cheonohchoo and rich people belong to the left, and spices, mint, etc. belong to the four.

After completion of the recovery operation, the interior is washed with water using a high-pressure washer.

(g) additive blending step

The collected mugwort extract solidifies after a certain period of time. Therefore, in order to keep the mugwort extract in a state that can be used at all times, it is necessary to store it in combination with additives.

At this time, the blending ratio of mugwort as a group is preferably used in a weight ratio of 10: 7: 5: 3.

As such additives, sesame oil is sour, glycerin is left, and vaseline, petroleum jelly, propolis, royal jelly, etc. are cider. It may be desirable to store mugwort by combining one or more components selected from among them in a certain ratio.

According to the prescription of the disease, it can be formulated in the weight ratio of Gunsinjwasa (10:7:5:3).

In addition, the additive may be made of liquor including soju, and the mixing ratio of mugwort and liquor may be selected and mixed within a weight ratio of 1:50 and then consumed by drinking.

(h) packaging step

The mugwort concentrate obtained in this way is packaged in a certain unit by a conventional method. In addition, it may be desirable to put a certain amount of the product into an aluminum pack, nylon laminate, PEG pack, or PET resin container, and seal it with silica gel.

The present invention, which found conditions for obtaining high-quality mugwort extract with high purity, applied the high-quality mugwort extract to the affected area and irradiated bio-ceramic source infrared rays to infiltrate the high-purity mugwort extract through the skin to the bone marrow, resulting in countless capillaries The effect can be further increased by providing necessary nutrition and lymph immunity to the cells while piercing the blockage.

The toxicity of the mugwort extract prepared by the present invention is evaporated as a non-condensable gas, and only mild medicinal properties remain without side effects, and it can be used most ideally by irradiating bioceramic near-infrared rays.

Although the present invention has shown various processes for preparing mugwort concentrate, it goes without saying that a form prepared by mixing mugwort and other ingredients may be included in the present invention.

Such other ingredients are not limited to herbal medicines and may comprehensively include all available plants.

According to the manufacturing method of such a moxibustion lozenge for mugwort, it is environmentally friendly because it properly contains active ingredients and at the same time there is no concern about the generation of smoke.

The mugwort extract obtained in the above way can be applied in the form of a patch to the skin of the painful area. In addition, the treatment effect can be doubled by applying far-infrared rays or heat to the place where the plaster is attached.

<Example>

Hereinafter, the present invention will be described in more detail through examples. These examples are only for explaining the present invention in more detail, and it will be apparent to those skilled in the art that the scope of the present invention is not limited by these examples according to the gist of the present invention. .

Example 1: Preparation of mugwort extract

After drying the pretreated mugwort, it was dried to a size of 20 mesh, and then mugwort extract was mass-produced using the combustion and condensation device shown in FIG. 4.

Test Example 1: Sensory evaluation

In the sensory test for the mugwort extract according to Example 1, 30 sensory testers with sensory identification were selected and the moxa moxibustion was applied twice (face pack, crown of the head, capillaries of body organs, etc.), and then the quality of the The evaluation scale was a 7-point scale (7 points: very good, 6 points: good, 5 points: slightly good, 4 points: normal, 3 points: slightly bad, 2 points: bad, 1 point: very bad).

As a sensory test item, two sensory items were evaluated for improvement of blood circulation disorder and nervous breakdown, and the results were verified by Duncan's multiple range test at the 5% level using ANOVA to verify a significant difference between each sample.

The results are shown in Table 1 (average value ± standard deviation) below. A commercially available product was used as a comparative product.

item Example 1 comparative example Improvement of blood circulation disorder 6.31±0.35 4.20±1.06 improvement of nervous breakdown 6.05±0.06 4.06±0.36 overall sign 6.21±0.72 4.13±0.75

As a result, the product of Example 1 showed remarkably excellent results in improving blood circulation disorders.

Clinical Example 1: Drinking and pharmacopuncture injection

The extract according to Example 1 was mixed with soju (1:10 weight ratio) so that it could be taken for drinking to see the effect of moxibustion in the intestines, and the effect of mugwort by penetrating the skin with pharmacopuncture injections.

Clinical Example 2: A near-infrared heater was irradiated with the moxibustion prepared by the method according to Example 1 of the present invention while applying moxa directly to a patient who could not walk on the subway stairs due to knee pain. As a result, the knee pain symptoms disappeared.

Clinical Example 3: Diabetes was so severe that the left little toe rotted and smelled, but the moxibustion prepared by the method according to Example 1 of the present invention was moxibusted with a direct ball and irradiated with a near-infrared heater, and as a result, new flesh came out.

Example 2: Preparation of mugwort extract Gopas

An active ingredient carrying layer solution was prepared by mixing 3 g of mugwort essence prepared in Example 1, 6.6 g of Eudragit E-100, a polymer solvent for matrix formation, and 0.4 g of isopropyl myristrate. In addition, 25 g of DT-9301 as an acrylic pressure-sensitive adhesive having a solid content between 35 and 42% was used as a solution to be used for the control-release adhesive layer, and 0.3 g of polyvinylpyrrolidone (Kollidon 25) was added to prepare a control-release adhesive layer.

The active ingredient supporting layer solution was applied on a polyester film using a lab coater, and then completely dried for 5 minutes at 50° C. and 100 RPM to form an active ingredient supporting layer. In addition, the release-controlling adhesive layer was coated with a release-controlling adhesive layer solution on a PET release film, then dried in a lab coater at 100°C and 1300RPM for 5 minutes to completely dry the solvent, and then removing the release film of the active ingredient carrying layer. It was laminated with the release-controlling adhesive layer. Thus, the paste containing the active ingredient according to the present invention was completed.

Clinical Example 4: As a result of applying Gopas, a mugwort extract prepared by the method of Example 2 of the present invention, to a patient with low back pain, it was confirmed that the symptoms of back pain disappeared.

The present invention described above is not limited by the foregoing embodiments and the accompanying drawings, and in the technical field to which the present invention belongs, the general It will be clear to those who have knowledge.

100: combustion device
110: combustion chamber
120: mugwort box filter
130: mugwort smoke purification room
140: mugwort smoke purification chamber box
200: condensation device
210: housing
211, 212: condensation plate
220: viewing window
230: thermometer
231: automatic temperature sensor
241: humidity sensor
250: vibrator
260: condensate recovery port
270: non-condensing gas pipe
280: damper
290: blower
295: anti-vibration spring

Claims (4)

An upper impermeable support layer (10); A drug delivery layer (20) containing mugwort extract located below the support layer (10) as an active ingredient; A controlled-release adhesive layer 30 located below the drug delivery layer 20 and in contact with the skin, and a release layer 140 attached to the back surface of the adhesive layer 30 and peeled off during use; The drug delivery layer 20 includes 20 to 40 parts by weight of mugwort extract, 50 to 60 parts by weight of a water-soluble polymer solvent for matrix formation, and 2 to 10 parts by weight of a skin penetration enhancer,
The mugwort extract is prepared by (a) pre-treating the mugwort to remove foreign substances; (b) drying the pretreated mugwort; (c) crushing the dried mugwort; (d) putting the extracted mugwort into the combustion chamber of the combustion device 100 and burning it; (e) condensing the smoke generated by the combustion process in the condensing device 200; (f) recovering the condensed solids; (g) blending additives into the recovered condensate; And (h) packaging the blended condensate; prepared by a method for producing mugwort containing,
Mugwort essence and paste first mix active ingredients including mugwort essence with a water-soluble polymer solvent and a skin permeation enhancer for matrix formation to form a drug delivery layer (20), then apply it on a support, and at 40 to 80 ° C. It is prepared by drying to form an active ingredient supporting layer and then laminating the adhesive layer 30 and the release layer 40,
The support layer 10 is made of a polyurethane or polyethylene film, and the release-controlled adhesive layer 30 includes 80 to 95 parts by weight of a polyacrylate block copolymer, 1 to 10 parts by weight of a water-soluble polymer, and a skin penetration enhancer. 2 to 10 parts by weight, the release layer 140 is made of a polyester film,
The combustion device 100 has an upper combustion chamber 110, a mugwort box filter 120 located below the combustion chamber 110, a mugwort smoke purification chamber 130 located below the mugwort box filter 120, and The mugwort smoke purification chamber box 140 located at the bottom of the mugwort smoke purification chamber 130 is vertically arranged,
The condensing device 200 includes a housing 210 having a hexahedral shape, a viewing window 220 provided on one side of the housing 210, a thermometer 230 provided in the upper center of the housing 210, and an automatic temperature sensor. 231, a humidity sensor 241 provided at the bottom of the non-condensable gas discharge, condensation plates 211 and 212 repeatedly and regularly arranged inside the housing 210, attached to both outer and lower surfaces of the housing 210 a vibrator 250, one or more condensate recovery outlets 260 provided at the bottom of the housing 210, a plurality of anti-vibration springs 295 attached to the bottom of the housing 210, and a rear end of the housing 210. It includes a non-condensing gas pipe 270 installed in communication, a damper 280 and a blower 290 sequentially installed inside the outlet side of the non-condensing gas pipe 270, and the housing 210 is inclined at a certain angle characterized in that it is placed,
The mugwort extract is prepared by burning mugwort, frankincense, myrrh, cinnamon tree, balsam or lacquer, cheonohchoo or rich, spice or mint together, and they are blended in a weight ratio of 10:7:5:3 ,
The mugwort extract is formulated with an additive, and the mugwort extract is mixed with: sesame oil: glycerin: vaseline, petroleum jelly, propolis, or royal jelly in a weight ratio of 10: 7: 5: 3 Characterized in that Wormwood extract gopas. delete delete delete