KR102522263B1 - polX 패밀리의 DNA 폴리머라제의 변형체 - Google Patents

polX 패밀리의 DNA 폴리머라제의 변형체 Download PDF

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KR102522263B1
KR102522263B1 KR1020187034921A KR20187034921A KR102522263B1 KR 102522263 B1 KR102522263 B1 KR 102522263B1 KR 1020187034921 A KR1020187034921 A KR 1020187034921A KR 20187034921 A KR20187034921 A KR 20187034921A KR 102522263 B1 KR102522263 B1 KR 102522263B1
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KR20190024883A (ko
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토마스 이버트
마크 델라뤼
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디엔에이 스크립트
앵스티띠 파스퇴르
상뜨로 나쇼날 드 라 러쉐르쉐 샹띠피크
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1264—DNA nucleotidylexotransferase (2.7.7.31), i.e. terminal nucleotidyl transferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07031—DNA nucleotidylexotransferase (2.7.7.31), i.e. terminal deoxynucleotidyl transferase

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  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020187034921A 2016-06-14 2017-06-13 polX 패밀리의 DNA 폴리머라제의 변형체 Active KR102522263B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1655475 2016-06-14
FR1655475A FR3052462A1 (fr) 2016-06-14 2016-06-14 Variants d'une adn polymerase de la famille polx
PCT/FR2017/051519 WO2017216472A2 (fr) 2016-06-14 2017-06-13 Variants d'une adn polymérase de la famille polx

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KR20190024883A KR20190024883A (ko) 2019-03-08
KR102522263B1 true KR102522263B1 (ko) 2023-04-18

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US (3) US20200002690A1 (https=)
EP (1) EP3469075A2 (https=)
JP (2) JP7118510B2 (https=)
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CN (1) CN109477080A (https=)
AU (2) AU2017286477C1 (https=)
CA (1) CA3024184A1 (https=)
FR (2) FR3052462A1 (https=)
IL (1) IL263503B2 (https=)
SG (2) SG11201809961TA (https=)
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IL263503A (en) 2019-02-03
IL263503B1 (en) 2024-12-01
AU2023282219A1 (en) 2024-01-18
US20230167421A1 (en) 2023-06-01
SG10202009688QA (en) 2020-11-27
IL263503B2 (en) 2025-04-01
JP7118510B2 (ja) 2022-08-16
CA3024184A1 (en) 2017-12-21
WO2017216472A3 (fr) 2018-03-15
FR3053699A1 (fr) 2018-01-12
FR3052462A1 (fr) 2017-12-15
US20200002690A1 (en) 2020-01-02
AU2017286477B2 (en) 2023-09-14
CN109477080A (zh) 2019-03-15
SG11201809961TA (en) 2018-12-28
JP2022137127A (ja) 2022-09-21
AU2017286477C1 (en) 2023-12-21
KR20190024883A (ko) 2019-03-08
EP3469075A2 (fr) 2019-04-17
JP2019517799A (ja) 2019-06-27
AU2017286477A1 (en) 2018-12-06
FR3053699B1 (fr) 2021-04-02
WO2017216472A2 (fr) 2017-12-21
US20240124855A1 (en) 2024-04-18

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