KR102497063B1 - B형 간염 바이러스에 대한 백신 - Google Patents

B형 간염 바이러스에 대한 백신 Download PDF

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KR102497063B1
KR102497063B1 KR1020227003308A KR20227003308A KR102497063B1 KR 102497063 B1 KR102497063 B1 KR 102497063B1 KR 1020227003308 A KR1020227003308 A KR 1020227003308A KR 20227003308 A KR20227003308 A KR 20227003308A KR 102497063 B1 KR102497063 B1 KR 102497063B1
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KR20220019846A (ko
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베르트랑 빅토르 질베르 조르쥬
칼턴 브래들리 브라운
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알티뮨 유케이 리미티드
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • A61K39/292Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01DNA viruses
    • C07K14/02Hepadnaviridae, e.g. hepatitis B virus
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/58Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
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    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10171Demonstrated in vivo effect

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  • Health & Medical Sciences (AREA)
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  • Virology (AREA)
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  • Microbiology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Wood Science & Technology (AREA)
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  • Gastroenterology & Hepatology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020227003308A 2012-12-24 2013-12-20 B형 간염 바이러스에 대한 백신 Active KR102497063B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020237003896A KR102625645B1 (ko) 2012-12-24 2013-12-20 B형 간염 바이러스에 대한 백신

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB1223386.2 2012-12-24
GBGB1223386.2A GB201223386D0 (en) 2012-12-24 2012-12-24 Vaccine
KR1020157020103A KR102358621B1 (ko) 2012-12-24 2013-12-20 B형 간염 바이러스에 대한 백신
PCT/GB2013/053410 WO2014102540A1 (en) 2012-12-24 2013-12-20 Vaccines against hepatitis b virus

Related Parent Applications (1)

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KR1020157020103A Division KR102358621B1 (ko) 2012-12-24 2013-12-20 B형 간염 바이러스에 대한 백신

Related Child Applications (1)

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KR1020237003896A Division KR102625645B1 (ko) 2012-12-24 2013-12-20 B형 간염 바이러스에 대한 백신

Publications (2)

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KR20220019846A KR20220019846A (ko) 2022-02-17
KR102497063B1 true KR102497063B1 (ko) 2023-02-06

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Application Number Title Priority Date Filing Date
KR1020227003308A Active KR102497063B1 (ko) 2012-12-24 2013-12-20 B형 간염 바이러스에 대한 백신
KR1020157020103A Expired - Fee Related KR102358621B1 (ko) 2012-12-24 2013-12-20 B형 간염 바이러스에 대한 백신
KR1020237003896A Active KR102625645B1 (ko) 2012-12-24 2013-12-20 B형 간염 바이러스에 대한 백신

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Application Number Title Priority Date Filing Date
KR1020157020103A Expired - Fee Related KR102358621B1 (ko) 2012-12-24 2013-12-20 B형 간염 바이러스에 대한 백신
KR1020237003896A Active KR102625645B1 (ko) 2012-12-24 2013-12-20 B형 간염 바이러스에 대한 백신

Country Status (12)

Country Link
US (3) US10300132B2 (enExample)
EP (2) EP3995146A1 (enExample)
JP (3) JP6811014B2 (enExample)
KR (3) KR102497063B1 (enExample)
CN (2) CN104903343A (enExample)
CA (1) CA2895459A1 (enExample)
DK (1) DK2935313T3 (enExample)
EA (1) EA201591213A1 (enExample)
ES (1) ES2906110T3 (enExample)
GB (1) GB201223386D0 (enExample)
PL (1) PL2935313T3 (enExample)
WO (1) WO2014102540A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0408164D0 (en) * 2004-04-13 2004-05-19 Immune Targeting Systems Ltd Antigen delivery vectors and constructs
GB201022147D0 (en) * 2010-12-31 2011-02-16 Immune Targeting Systems Its Ltd Formulation
GB201223386D0 (en) * 2012-12-24 2013-02-06 Immune Targeting Systems Its Ltd Vaccine
WO2016020538A1 (en) * 2014-08-08 2016-02-11 Transgene Sa Hbv vaccine and antibody combination therapy to treat hbv infections
CN106610423A (zh) * 2015-10-26 2017-05-03 复旦大学 评价疫苗疗效的细胞免疫学检测试剂盒及其储存方法
RS65007B1 (sr) 2016-06-02 2024-01-31 Ultimovacs Asa Vakcina u kombinaciji sa inhibitorom imunološke kontrolne tačke za primenu u lečenju kancera
MY201964A (en) 2016-06-20 2024-03-27 Isa Pharmaceuticals B V Formulation of a peptide vaccine
CA3085492A1 (en) * 2017-12-19 2019-06-27 Janssen Sciences Ireland Unlimited Company Methods and apparatus for the delivery of hepatitis b virus (hbv) vaccines
CA3096056A1 (en) * 2018-04-04 2019-10-10 Altimmune, Inc. T-cell inducing vaccine composition combinations and uses thereof
WO2020145901A1 (en) * 2019-01-11 2020-07-16 Agency For Science, Technology And Research Use of hla-a*11:01-restricted hepatitis b virus (hbv) peptides for identifying hbv-specific cd8+ t cells
WO2020255018A1 (en) * 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Hepatitis b virus (hbv) vaccines and uses thereof
KR20220090497A (ko) * 2019-08-29 2022-06-29 비르 바이오테크놀로지, 인코포레이티드 B형 간염 바이러스 백신
AU2020397499A1 (en) 2019-12-07 2022-06-16 Erasmus University Medical Center Rotterdam Treatment of diseases related to hepatitis B virus
US20230063089A1 (en) * 2020-01-09 2023-03-02 Virion Therapeutics, Llc Adenoviral vectors encoding hepatitis b viral antigens fused to herpes virus glycoprotein d and methods of using the same
WO2023085956A1 (en) * 2021-11-09 2023-05-19 Avalia Immunotherapies Limited Novel therapeutic vaccines

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993003753A1 (en) * 1991-08-26 1993-03-04 The Scripps Research Institute Peptides for inducing cytotoxic t-lymphocyte responses to hepatitis b virus
WO1995003777A1 (en) * 1993-08-02 1995-02-09 The Scripps Research Institute Peptides for inducing cytotoxic t lymphocyte responses to hepatitis b virus
JP2004508320A (ja) * 2000-09-08 2004-03-18 エピミューン インコーポレイテッド ペプチドおよび核酸組成物を用いるb型肝炎ウイルスに対する細胞性免疫応答の誘導
JP2007532614A (ja) * 2004-04-13 2007-11-15 イミューン ターゲティング システムズ 抗原デリバリベクタ及びコンストラクト

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6607727B1 (en) * 1991-08-26 2003-08-19 The Scripps Research Institute Peptides for inducing cytotoxic T lymphocyte responses to hepatitus B virus
US10076570B2 (en) * 2009-08-07 2018-09-18 Transgene S.A. Composition for treating HBV infection
GB201022147D0 (en) 2010-12-31 2011-02-16 Immune Targeting Systems Its Ltd Formulation
GB201223386D0 (en) * 2012-12-24 2013-02-06 Immune Targeting Systems Its Ltd Vaccine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993003753A1 (en) * 1991-08-26 1993-03-04 The Scripps Research Institute Peptides for inducing cytotoxic t-lymphocyte responses to hepatitis b virus
WO1995003777A1 (en) * 1993-08-02 1995-02-09 The Scripps Research Institute Peptides for inducing cytotoxic t lymphocyte responses to hepatitis b virus
JP2004508320A (ja) * 2000-09-08 2004-03-18 エピミューン インコーポレイテッド ペプチドおよび核酸組成物を用いるb型肝炎ウイルスに対する細胞性免疫応答の誘導
JP2007532614A (ja) * 2004-04-13 2007-11-15 イミューン ターゲティング システムズ 抗原デリバリベクタ及びコンストラクト

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Publication number Publication date
US11918645B2 (en) 2024-03-05
US10300132B2 (en) 2019-05-28
EP2935313B1 (en) 2021-11-24
EP3995146A1 (en) 2022-05-11
KR20220019846A (ko) 2022-02-17
KR102358621B1 (ko) 2022-02-03
CN104903343A (zh) 2015-09-09
JP2021098711A (ja) 2021-07-01
JP2019034946A (ja) 2019-03-07
KR20150098676A (ko) 2015-08-28
US20230090379A1 (en) 2023-03-23
KR20230021771A (ko) 2023-02-14
DK2935313T3 (da) 2022-02-28
KR102625645B1 (ko) 2024-01-15
CN114028553A (zh) 2022-02-11
EP2935313A1 (en) 2015-10-28
JP6811014B2 (ja) 2021-01-13
JP7187237B2 (ja) 2022-12-12
US11382969B2 (en) 2022-07-12
ES2906110T3 (es) 2022-04-13
JP7235785B2 (ja) 2023-03-08
GB201223386D0 (en) 2013-02-06
JP2016505589A (ja) 2016-02-25
PL2935313T3 (pl) 2022-05-02
WO2014102540A1 (en) 2014-07-03
CA2895459A1 (en) 2014-07-03
EA201591213A1 (ru) 2016-02-29
US20160106830A1 (en) 2016-04-21
US20200016263A1 (en) 2020-01-16

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