KR102453184B1 - 트리테르펜 사포닌, 그의 합성 방법, 및 그의 용도 - Google Patents
트리테르펜 사포닌, 그의 합성 방법, 및 그의 용도 Download PDFInfo
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- KR102453184B1 KR102453184B1 KR1020217015136A KR20217015136A KR102453184B1 KR 102453184 B1 KR102453184 B1 KR 102453184B1 KR 1020217015136 A KR1020217015136 A KR 1020217015136A KR 20217015136 A KR20217015136 A KR 20217015136A KR 102453184 B1 KR102453184 B1 KR 102453184B1
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- oxygen
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- adjuvant
- sulfur
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| US10806119B2 (en) | 2013-06-05 | 2020-10-20 | Yeda Research And Development Co. Ltd. | Plant with altered content of steroidal alkaloids |
| ES2914176T3 (es) | 2013-09-17 | 2022-06-07 | Obi Pharma Inc | Composiciones de una vacuna glucídica para inducir respuestas inmunitarias y usos de las mismas en el tratamiento de cáncer |
| CA2950750C (en) | 2014-05-30 | 2023-01-10 | David Y. Gin | Minimal saponin analogues, synthesis and use thereof |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| KR20180050339A (ko) | 2015-09-04 | 2018-05-14 | 오비아이 파머 인코퍼레이티드 | 글리칸 어레이 및 사용 방법 |
| US20180327436A1 (en) | 2015-11-06 | 2018-11-15 | Adjuvance Technologies, Inc. | Triterpene saponin analogues |
| US10980894B2 (en) | 2016-03-29 | 2021-04-20 | Obi Pharma, Inc. | Antibodies, pharmaceutical compositions and methods |
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| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| CN110869025A (zh) * | 2017-04-13 | 2020-03-06 | 佐剂技术公司 | 三萜皂苷合成、中间体和佐剂组合 |
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| US11324821B2 (en) | 2017-10-16 | 2022-05-10 | Adjuvance Technologies, Inc. | Triterpene saponin analogues |
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| US12497429B2 (en) * | 2018-03-20 | 2025-12-16 | The Uab Research Foundation | Saponin-based vaccine adjuvants |
| US11203645B2 (en) | 2018-06-27 | 2021-12-21 | Obi Pharma, Inc. | Glycosynthase variants for glycoprotein engineering and methods of use |
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| US20220409721A1 (en) * | 2019-11-05 | 2022-12-29 | Adjuvance Technologies, Inc. | Varicella zoster |
| US20230128815A1 (en) * | 2020-03-23 | 2023-04-27 | Adjuvance Technologies, Inc. | Adjuvant compounds, salt forms, and formulations |
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| US20230190920A1 (en) | 2021-12-19 | 2023-06-22 | Massachusetts Institute Of Technology | Compositions and methods for long-lasting germinal center responses to a priming immunization |
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| CN101322734B (zh) | 2008-07-22 | 2013-05-29 | 沈阳药科大学 | 具有抗炎免疫作用的轮叶党参总皂苷及其制备方法 |
| CA2950750C (en) * | 2014-05-30 | 2023-01-10 | David Y. Gin | Minimal saponin analogues, synthesis and use thereof |
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Non-Patent Citations (1)
| Title |
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| Yong-Jae Kim et.al., Synthetic Studies of complex Immunostimulants from Quillajasaponaria~, J.AM.CHEM.SOC., Vol.128, pp.11906-11915(2006.) 1부.* |
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