KR102450674B1 - 안과용 조성물 및 이의 사용 방법 - Google Patents
안과용 조성물 및 이의 사용 방법 Download PDFInfo
- Publication number
- KR102450674B1 KR102450674B1 KR1020177028161A KR20177028161A KR102450674B1 KR 102450674 B1 KR102450674 B1 KR 102450674B1 KR 1020177028161 A KR1020177028161 A KR 1020177028161A KR 20177028161 A KR20177028161 A KR 20177028161A KR 102450674 B1 KR102450674 B1 KR 102450674B1
- Authority
- KR
- South Korea
- Prior art keywords
- composition
- corneal
- cornea
- dexamethasone
- eye
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
- A01H5/02—Flowers
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
- A01H6/42—Geraniaceae, e.g. Geranium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
-
- Y10S514/912—
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Peptides Or Proteins (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Physiology (AREA)
- Botany (AREA)
- Developmental Biology & Embryology (AREA)
- Environmental Sciences (AREA)
- Eyeglasses (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ705727 | 2015-03-05 | ||
| NZ70572715 | 2015-03-05 | ||
| PCT/NZ2016/050033 WO2016140581A1 (en) | 2015-03-05 | 2016-03-04 | Ophthalmic compositions and methods of use therefor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20170132197A KR20170132197A (ko) | 2017-12-01 |
| KR102450674B1 true KR102450674B1 (ko) | 2022-10-04 |
Family
ID=56848288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020177028161A Active KR102450674B1 (ko) | 2015-03-05 | 2016-03-04 | 안과용 조성물 및 이의 사용 방법 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10842850B2 (https=) |
| EP (1) | EP3265096B9 (https=) |
| JP (4) | JP2018513117A (https=) |
| KR (1) | KR102450674B1 (https=) |
| CN (1) | CN107530360B (https=) |
| AU (1) | AU2016226699B2 (https=) |
| ES (1) | ES2952700T3 (https=) |
| MY (1) | MY186271A (https=) |
| SG (1) | SG11201708114SA (https=) |
| TW (1) | TWI747816B (https=) |
| WO (1) | WO2016140581A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9622911B2 (en) | 2010-09-30 | 2017-04-18 | Cxl Ophthalmics, Llc | Ophthalmic treatment device, system, and method of use |
| EP2830627B1 (en) | 2012-03-29 | 2024-05-01 | Epion Therapeutics, Inc. | Ocular treatment solutions, delivery devices and delivery augmentation methods |
| ES2986057T3 (es) | 2012-03-29 | 2024-11-08 | Epion Therapeutics Inc | Composiciones y métodos para tratar o prevenir enfermedades asociadas al estrés oxidativo |
| TWI747816B (zh) | 2015-03-05 | 2021-12-01 | 紐西蘭商奧克蘭聯合服務有限公司 | 眼用組合物用於製備藥物的用途 |
| KR102706856B1 (ko) | 2015-07-21 | 2024-09-19 | 아베드로 인코퍼레이티드 | 광증감제로 눈을 치료하기 위한 시스템 및 방법 |
| CN110092816B (zh) * | 2018-01-29 | 2023-08-01 | 上海市第一人民医院 | 预防和治疗纤维化的小分子多肽及其应用 |
| US20210060017A1 (en) * | 2018-02-27 | 2021-03-04 | Shilpa Medicare Ltd | Methotrexate ophthalmic solution |
| CN108728418A (zh) * | 2018-06-19 | 2018-11-02 | 新乡医学院 | 一种鸡胚中枢神经系统单个神经元动态研究模型的制备方法及应用 |
| WO2020092897A1 (en) * | 2018-11-02 | 2020-05-07 | Senseonics, Incorporated | Drug eluting matrix on analyte indicator |
| GB201820021D0 (en) * | 2018-12-07 | 2019-01-23 | Univ Birmingham | Ocular hydrogel compositions |
| JP2022125941A (ja) * | 2021-02-17 | 2022-08-29 | 株式会社ティ・エム・ディ | コンタクトレンズ |
| JP2025529178A (ja) | 2022-09-01 | 2025-09-04 | オプティファイ・セラピューティクス・アクティエンゲゼルシャフト | 眼科用組成物 |
| EP4687950A1 (en) * | 2023-03-30 | 2026-02-11 | Cetel Scientific LLC | Amniotic and chorionic collagen for ocular surface healing |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10842850B2 (en) | 2015-03-05 | 2020-11-24 | Auckland Uniservices Limited | Ophthalmic compositions and methods of use therefor |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3786812A (en) * | 1972-03-10 | 1974-01-22 | C Neefe | Contact lens for olar drug delivery |
| US4177268A (en) | 1973-05-30 | 1979-12-04 | Jouveinal S.A. | Method of alleviating inflammation by administration of dexamethasone derivatives |
| US5124392A (en) * | 1988-10-03 | 1992-06-23 | Alcon Laboratories, Inc. | Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation |
| AU660635B2 (en) * | 1990-11-16 | 1995-07-06 | Celtrix Pharmaceuticals, Inc. | A beta-type transforming growth factor |
| US5411940A (en) | 1993-09-29 | 1995-05-02 | Alcon Laboratories, Inc. | Use of TGF-β3 to reduce the formation of scar tissue in response to corneal trauma |
| CN1770976A (zh) | 2003-02-13 | 2006-05-10 | 人类起源公司 | 利用脐带血治疗患有疾病、紊乱或状况的个体的用途 |
| MXPA03011987A (es) | 2003-12-19 | 2005-06-23 | Osio Sancho Alberto | Metodo para el tratamiento de la presbicia induciendo cambios en el poder y fisiologia corneal. |
| WO2007099337A1 (en) | 2006-03-01 | 2007-09-07 | Cartela R&D Ab | Expansion and differentiation of mesenchymal stem cells |
| GB0604938D0 (en) | 2006-03-11 | 2006-04-19 | Renovo Ltd | Proteins, nucleic acids and medicaments |
| US7767217B2 (en) | 2006-03-14 | 2010-08-03 | Foresight Biotherapeutics | Ophthalmic compositions comprising povidone-iodine |
| US8110655B2 (en) | 2006-11-13 | 2012-02-07 | Auxagen, Inc. | Method to promote hair growth and/or delay or treat hair loss by administering a TGF-β antagonist or inhibitor |
| AU2007319811A1 (en) | 2006-11-15 | 2008-05-22 | Coda Therapeutics, Inc. | Improved methods and compositions for wound healing |
| JP2011505409A (ja) | 2007-12-04 | 2011-02-24 | ノバガリ ファーマ エスエー | パルミチン酸デキサメタゾンのようなコルチコステロイドプロドラッグを含有する眼障害の治療用の組成物 |
| US7795316B1 (en) | 2007-12-19 | 2010-09-14 | Alcon Research, Ltd. | Topical ophthalmic compositions containing tobramycin and dexamethasone |
| EP2249921B1 (en) | 2008-02-25 | 2020-06-17 | Eyegate Pharmaceuticals, Inc. | Enhanced delivery of dexamethasone phosphate to ocular tissues through iontophoresis |
| EP2370054B1 (en) * | 2008-12-11 | 2015-10-07 | Massachusetts Institute of Technology | Contact lens drug delivery device |
| US10201548B2 (en) | 2009-03-06 | 2019-02-12 | Sun Pharma Global Fze | Methods for treating ocular inflammatory diseases |
| WO2012088044A2 (en) | 2010-12-20 | 2012-06-28 | James Mcmillan | Compositions and methods for improving ocular surface health, corneal clarity, optical function and maintaining visual acuity |
| US20130165419A1 (en) * | 2011-12-21 | 2013-06-27 | Insite Vision Incorporated | Combination anti-inflammatory ophthalmic compositions |
| KR101518370B1 (ko) | 2013-06-25 | 2015-05-07 | 가톨릭대학교 산학협력단 | Il-10 생성 조절 t세포로의 분화 유도용 조성물 |
| CN104548210A (zh) | 2014-12-13 | 2015-04-29 | 浙江大学 | 含地塞米松转化生长因子的可控缓释plga微球及制备 |
| US10537585B2 (en) | 2017-12-18 | 2020-01-21 | Dexcel Pharma Technologies Ltd. | Compositions comprising dexamethasone |
-
2016
- 2016-03-04 TW TW105106605A patent/TWI747816B/zh active
- 2016-03-04 WO PCT/NZ2016/050033 patent/WO2016140581A1/en not_active Ceased
- 2016-03-04 US US15/555,909 patent/US10842850B2/en active Active
- 2016-03-04 SG SG11201708114SA patent/SG11201708114SA/en unknown
- 2016-03-04 KR KR1020177028161A patent/KR102450674B1/ko active Active
- 2016-03-04 ES ES16759200T patent/ES2952700T3/es active Active
- 2016-03-04 AU AU2016226699A patent/AU2016226699B2/en active Active
- 2016-03-04 MY MYPI2017703238A patent/MY186271A/en unknown
- 2016-03-04 CN CN201680026065.0A patent/CN107530360B/zh active Active
- 2016-03-04 EP EP16759200.5A patent/EP3265096B9/en active Active
- 2016-03-04 JP JP2017546870A patent/JP2018513117A/ja active Pending
-
2020
- 2020-10-23 US US17/078,949 patent/US11938168B2/en active Active
-
2021
- 2021-01-27 JP JP2021011148A patent/JP2021091688A/ja active Pending
-
2023
- 2023-03-01 JP JP2023030945A patent/JP7641650B2/ja active Active
-
2024
- 2024-12-13 JP JP2024218517A patent/JP2025032318A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10842850B2 (en) | 2015-03-05 | 2020-11-24 | Auckland Uniservices Limited | Ophthalmic compositions and methods of use therefor |
Also Published As
| Publication number | Publication date |
|---|---|
| US11938168B2 (en) | 2024-03-26 |
| JP2018513117A (ja) | 2018-05-24 |
| AU2016226699B2 (en) | 2020-10-22 |
| NZ735959A (en) | 2021-10-29 |
| CN107530360A (zh) | 2018-01-02 |
| US20220047676A1 (en) | 2022-02-17 |
| WO2016140581A1 (en) | 2016-09-09 |
| MY186271A (en) | 2021-07-01 |
| KR20170132197A (ko) | 2017-12-01 |
| EP3265096B1 (en) | 2023-06-07 |
| JP7641650B2 (ja) | 2025-03-07 |
| TWI747816B (zh) | 2021-12-01 |
| TW201639592A (zh) | 2016-11-16 |
| US10842850B2 (en) | 2020-11-24 |
| JP2025032318A (ja) | 2025-03-11 |
| US20180050088A1 (en) | 2018-02-22 |
| ES2952700T3 (es) | 2023-11-03 |
| JP2023066425A (ja) | 2023-05-15 |
| EP3265096C0 (en) | 2023-06-07 |
| JP2021091688A (ja) | 2021-06-17 |
| AU2016226699A1 (en) | 2017-10-26 |
| EP3265096A1 (en) | 2018-01-10 |
| CN107530360B (zh) | 2021-09-17 |
| EP3265096A4 (en) | 2018-10-24 |
| SG11201708114SA (en) | 2017-11-29 |
| EP3265096B9 (en) | 2023-10-04 |
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