KR102375218B1 - T 세포 수용체 및 이를 사용하는 면역 요법 - Google Patents

T 세포 수용체 및 이를 사용하는 면역 요법 Download PDF

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KR102375218B1
KR102375218B1 KR1020217026811A KR20217026811A KR102375218B1 KR 102375218 B1 KR102375218 B1 KR 102375218B1 KR 1020217026811 A KR1020217026811 A KR 1020217026811A KR 20217026811 A KR20217026811 A KR 20217026811A KR 102375218 B1 KR102375218 B1 KR 102375218B1
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레오니 알텐
세바스티안 붕크
도미니크 마우러
클라우디아 바그너
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이매틱스 바이오테크놀로지스 게엠베하
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
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    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K—PEPTIDES
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    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
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KR1020217026811A 2016-12-08 2017-12-07 T 세포 수용체 및 이를 사용하는 면역 요법 Active KR102375218B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020227008109A KR20220038511A (ko) 2016-12-08 2017-12-07 T 세포 수용체 및 이를 사용하는 면역 요법

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662431588P 2016-12-08 2016-12-08
DE102016123847.3 2016-12-08
DE102016123847.3A DE102016123847B3 (de) 2016-12-08 2016-12-08 Neue T-Zellrezeptoren und deren Verwendung in Immuntherapie
US62/431,588 2016-12-08
KR1020197019005A KR20190088539A (ko) 2016-12-08 2017-12-07 T 세포 수용체 및 이를 사용하는 면역 요법
PCT/EP2017/081800 WO2018104438A1 (en) 2016-12-08 2017-12-07 Novel t cell receptors and immune therapy using the same

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KR1020197019005A Division KR20190088539A (ko) 2016-12-08 2017-12-07 T 세포 수용체 및 이를 사용하는 면역 요법

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KR1020227008109A Division KR20220038511A (ko) 2016-12-08 2017-12-07 T 세포 수용체 및 이를 사용하는 면역 요법

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KR20210109657A KR20210109657A (ko) 2021-09-06
KR102375218B1 true KR102375218B1 (ko) 2022-03-17

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KR1020247000927A Ceased KR20240007775A (ko) 2016-12-08 2017-12-07 T 세포 수용체 및 이를 사용하는 면역 요법
KR1020227008109A Abandoned KR20220038511A (ko) 2016-12-08 2017-12-07 T 세포 수용체 및 이를 사용하는 면역 요법

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KR1020227008109A Abandoned KR20220038511A (ko) 2016-12-08 2017-12-07 T 세포 수용체 및 이를 사용하는 면역 요법

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US (3) US10702609B2 (enExample)
EP (1) EP4032544A3 (enExample)
JP (3) JP7016543B2 (enExample)
KR (3) KR102375218B1 (enExample)
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WO2012104843A1 (en) 2011-02-06 2012-08-09 Yeda Research And Development Co.Ltd. At The Weizmann Institute Of Science Affinity maturated t cell receptors and use thereof
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