KR102296042B1 - 약물동역학 약물 투약 요법의 제공 - Google Patents

약물동역학 약물 투약 요법의 제공 Download PDF

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KR102296042B1
KR102296042B1 KR1020167001142A KR20167001142A KR102296042B1 KR 102296042 B1 KR102296042 B1 KR 102296042B1 KR 1020167001142 A KR1020167001142 A KR 1020167001142A KR 20167001142 A KR20167001142 A KR 20167001142A KR 102296042 B1 KR102296042 B1 KR 102296042B1
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patient
plasma protein
therapeutic plasma
dosing regimen
dosing
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KR20160022874A (ko
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알렉산드라 뢰브-바셀리
제랄드 디키 스파츠
명신 오
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다케다 야쿠힌 고교 가부시키가이샤
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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/50—Mutagenesis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/30—Unsupervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G16B5/20—Probabilistic models
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/30—Prediction of properties of chemical compounds, compositions or mixtures
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C99/00—Subject matter not provided for in other groups of this subclass
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Data Mining & Analysis (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Primary Health Care (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Databases & Information Systems (AREA)
  • Computing Systems (AREA)
  • Physiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Artificial Intelligence (AREA)
  • Evolutionary Computation (AREA)
  • Bioethics (AREA)
  • Software Systems (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
KR1020167001142A 2013-06-20 2014-06-20 약물동역학 약물 투약 요법의 제공 Active KR102296042B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020217026984A KR102352133B1 (ko) 2013-06-20 2014-06-20 약물동역학 약물 투약 요법의 제공

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361837421P 2013-06-20 2013-06-20
US61/837,421 2013-06-20
US201361840969P 2013-06-28 2013-06-28
US61/840,969 2013-06-28
US201361881214P 2013-09-23 2013-09-23
US61/881,214 2013-09-23
PCT/US2014/043517 WO2015006033A1 (en) 2013-06-20 2014-06-20 Providing a pharmacokinetic drug dosing regime

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020217026984A Division KR102352133B1 (ko) 2013-06-20 2014-06-20 약물동역학 약물 투약 요법의 제공

Publications (2)

Publication Number Publication Date
KR20160022874A KR20160022874A (ko) 2016-03-02
KR102296042B1 true KR102296042B1 (ko) 2021-08-31

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KR1020167001142A Active KR102296042B1 (ko) 2013-06-20 2014-06-20 약물동역학 약물 투약 요법의 제공
KR1020227015723A Ceased KR20220065097A (ko) 2013-06-20 2014-06-20 약물동역학 약물 투약 요법의 제공
KR1020217026984A Active KR102352133B1 (ko) 2013-06-20 2014-06-20 약물동역학 약물 투약 요법의 제공
KR1020227001162A Active KR102397974B1 (ko) 2013-06-20 2014-06-20 약물동역학 약물 투약 요법의 제공

Family Applications After (3)

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KR1020227015723A Ceased KR20220065097A (ko) 2013-06-20 2014-06-20 약물동역학 약물 투약 요법의 제공
KR1020217026984A Active KR102352133B1 (ko) 2013-06-20 2014-06-20 약물동역학 약물 투약 요법의 제공
KR1020227001162A Active KR102397974B1 (ko) 2013-06-20 2014-06-20 약물동역학 약물 투약 요법의 제공

Country Status (23)

Country Link
US (1) US20140379629A1 (https=)
EP (3) EP3879534A1 (https=)
JP (4) JP2016526542A (https=)
KR (4) KR102296042B1 (https=)
CN (2) CN105592973B (https=)
AU (3) AU2014287706B2 (https=)
BR (3) BR122022000127A8 (https=)
CA (1) CA2915472C (https=)
CL (1) CL2015003641A1 (https=)
EA (1) EA037962B1 (https=)
ES (1) ES2882832T3 (https=)
GE (4) GEAP201814039A (https=)
IL (3) IL279313B (https=)
MX (3) MX373454B (https=)
MY (2) MY176173A (https=)
NZ (1) NZ715216A (https=)
PH (1) PH12015502800B1 (https=)
PL (1) PL3010681T3 (https=)
SA (2) SA515370289B1 (https=)
SG (1) SG11201510515YA (https=)
UA (1) UA118109C2 (https=)
WO (1) WO2015006033A1 (https=)
ZA (1) ZA201600100B (https=)

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WO2013088318A1 (en) * 2011-12-13 2013-06-20 Koninklijke Philips Electronics N.V. Dose optimization based on outcome quality
US10083400B2 (en) 2012-10-05 2018-09-25 Diane R. MOULD System and method for providing patient-specific dosing as a function of mathematical models updated to account for an observed patient response
US10325687B2 (en) * 2013-12-06 2019-06-18 Bioverativ Therapeutics Inc. Population pharmacokinetics tools and uses thereof
CA2944909A1 (en) 2014-04-04 2015-10-08 Bloodworks Routine laboratory and point-of-care (poc) testing for hemostasis
US11062797B2 (en) * 2014-10-10 2021-07-13 Continuous Precision Medicine Method and system for obtaining and using pharmacokinetic data in drug administration
AU2016245862A1 (en) 2015-04-09 2018-02-22 Diane R. Mould Systems and methods for patient-specific dosing
WO2017136583A1 (en) * 2016-02-02 2017-08-10 Versartis, Inc. Growth hormone treatment adherence system
KR102415992B1 (ko) 2016-04-15 2022-07-04 다케다 야쿠힌 고교 가부시키가이샤 약물동역학 약물 투약 요법을 제공하는 방법 및 장치
JP6807015B2 (ja) * 2016-06-13 2021-01-06 ソニー株式会社 情報処理装置、情報処理方法、およびプログラム
US10896749B2 (en) * 2017-01-27 2021-01-19 Shire Human Genetic Therapies, Inc. Drug monitoring tool
US20190365317A1 (en) * 2017-02-01 2019-12-05 Shire Human Genetic Therapies, Inc. Physiological sensing and therapeutic administration system and method
WO2020163441A1 (en) * 2019-02-06 2020-08-13 Optimdosing Llc Smart multidosing
BE1027052A1 (fr) 2019-02-14 2020-09-07 Aardex Group Procede d'assistance a la prise ou a l'acte d'un traitement therapeutique
US10970651B1 (en) * 2019-12-02 2021-04-06 Sas Institute Inc. Analytic system for two-stage interactive graphical model selection
KR102420872B1 (ko) * 2020-12-18 2022-07-14 포항공과대학교 산학협력단 강화학습과 약동-약력학 모델을 이용한 연속 약물 투여량 결정 방법
CN113053508B (zh) * 2021-03-29 2024-07-26 深圳市科曼医疗设备有限公司 基于触控屏的交互控制方法及装置
US12444172B2 (en) * 2022-11-28 2025-10-14 GE Precision Healthcare LLC Variable confidence machine learning
CN116844662B (zh) * 2023-06-29 2026-03-27 中国科学技术大学 一种药剂投加方案的选取方法、装置和计算机可读介质

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JP2013512678A (ja) * 2009-12-06 2013-04-18 バイオジェン アイデック ヘモフィリア インコーポレイテッド 第ＶＩＩＩ−Ｆｃ因子キメラおよびハイブリッドポリペプチドならびにその使用法

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JP2008516303A (ja) * 2004-08-25 2008-05-15 カーディナル ヘルス ３０３、インコーポレイテッド 患者治療を動的に調整するシステムおよび方法
JP2013512678A (ja) * 2009-12-06 2013-04-18 バイオジェン アイデック ヘモフィリア インコーポレイテッド 第ＶＩＩＩ−Ｆｃ因子キメラおよびハイブリッドポリペプチドならびにその使用法

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JP6813237B2 (ja) 2021-01-13
IL274848A (en) 2020-07-30
BR112015031856A8 (pt) 2022-08-30
EP3309696A1 (en) 2018-04-18
GEAP201814039A (en) 2018-03-26
EP3879534A1 (en) 2021-09-15
GEP20196990B (en) 2019-07-10
AU2020202664A1 (en) 2020-05-14
MX373454B (es) 2020-04-23
EP3010681B1 (en) 2021-05-19
MX2023000359A (es) 2023-02-13
JP2021061012A (ja) 2021-04-15
JP2022105022A (ja) 2022-07-12
CL2015003641A1 (es) 2016-10-28
AU2020202664B2 (en) 2022-06-02
ES2882832T3 (es) 2021-12-02
BR122022000127A2 (https=) 2017-07-25
AU2017272293B2 (en) 2020-01-23
WO2015006033A1 (en) 2015-01-15
JP2016526542A (ja) 2016-09-05
AU2017272293A1 (en) 2018-01-04
KR102352133B1 (ko) 2022-01-18
KR20220011217A (ko) 2022-01-27
PH12015502800B1 (en) 2018-10-24
GEP20186882B (en) 2018-07-25
KR20160022874A (ko) 2016-03-02
SA521430246B1 (ar) 2022-09-14
NZ715216A (en) 2020-07-31
KR102397974B1 (ko) 2022-05-13
IL243208A0 (en) 2016-02-29
CN105592973A (zh) 2016-05-18
BR122020013811A8 (pt) 2022-08-30
PL3010681T3 (pl) 2021-11-15
BR122020013811A2 (https=) 2017-07-25
BR122022000127A8 (pt) 2022-08-30
IL279313A (en) 2021-01-31
JP2019196352A (ja) 2019-11-14
MX2015017878A (es) 2016-09-14
US20140379629A1 (en) 2014-12-25
JP7398031B2 (ja) 2023-12-14
CN105592973B (zh) 2020-06-19
MX2020004112A (es) 2020-07-24
PH12015502800A1 (en) 2016-03-14
AU2014287706B2 (en) 2017-10-05
EP3010681A1 (en) 2016-04-27
KR20220065097A (ko) 2022-05-19
CA2915472A1 (en) 2015-01-15
KR20210110736A (ko) 2021-09-08
MY176173A (en) 2020-07-24
JP7060291B2 (ja) 2022-04-26
CN111508557A (zh) 2020-08-07
CA2915472C (en) 2023-09-19
CN111508557B (zh) 2024-03-26
BR112015031856A2 (pt) 2017-07-25
EP3010681A4 (en) 2017-03-08
UA118109C2 (uk) 2018-11-26
SA515370289B1 (ar) 2022-02-02
MY195911A (en) 2023-02-27
IL243208B (en) 2020-06-30
SG11201510515YA (en) 2016-01-28
EA201690048A1 (ru) 2016-05-31
EA037962B1 (ru) 2021-06-16
IL279313B (en) 2022-08-01
AU2014287706A1 (en) 2016-01-21
ZA201600100B (en) 2019-09-25
GEAP201914559A (en) 2019-02-11

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