BR122022000127A8 - Método para fornecer um regime terapêutico de dosagem de proteína plasmática e aparelho que compreende instruções armazenadas no mesmo que são configuradas, quando executadas, para fazer com que o aparelho execute um procedimento para determinar um regime de dosagem - Google Patents
Método para fornecer um regime terapêutico de dosagem de proteína plasmática e aparelho que compreende instruções armazenadas no mesmo que são configuradas, quando executadas, para fazer com que o aparelho execute um procedimento para determinar um regime de dosagemInfo
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- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/50—Mutagenesis
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/20—Supervised data analysis
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/30—Unsupervised data analysis
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
- G16B5/20—Probabilistic models
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/30—Prediction of properties of chemical compounds, compositions or mixtures
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
- G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C99/00—Subject matter not provided for in other groups of this subclass
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Abstract
A presente invenção refere-se a um sistema e a um método para prover um regime de dosagem de droga de proteína plasmática terapêutica que incluem determinar um perfil farmacocinético de um paciente usando um modelo Bayesiano de perfis farmacocinéticos de pacientes amostrados. O sistema e o método exemplificativos também incluem determinar um primeiro regime de dosagem para um primeiro intervalo de dosagem específico incluindo (i) uma primeira dosagem e (ii) um primeiro nível de proteína plasmática terapêutica no paciente sobre um período de tempo com base pelo menos no perfil farmacocinético e determinar um segundo regime de dosagem para um segundo intervalo de dosagem específico incluindo (i) uma segunda dosagem e (ii) um segundo nível de proteína plasma terapêutico no paciente sobre o período de tempo com base pelo menos no perfil farmacocinético. O sistema e o método exemplificativos adicionalmente incluem exibir o primeiro regime de dosagem e o segundo regime de dosagem em um dispositivo de cliente de tal modo que o primeiro regime de dosagem seja exibido em conjunção com o segundo regime de dosagem.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361837421P | 2013-06-20 | 2013-06-20 | |
US201361840969P | 2013-06-28 | 2013-06-28 | |
US201361881214P | 2013-09-23 | 2013-09-23 | |
PCT/US2014/043517 WO2015006033A1 (en) | 2013-06-20 | 2014-06-20 | Providing a pharmacokinetic drug dosing regime |
Publications (2)
Publication Number | Publication Date |
---|---|
BR122022000127A2 BR122022000127A2 (pt) | 2017-07-25 |
BR122022000127A8 true BR122022000127A8 (pt) | 2022-08-30 |
Family
ID=52111779
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015031856A BR112015031856A8 (pt) | 2013-06-20 | 2014-06-20 | Aparelho para prover um regime de dosagem de proteína plasmática terapêutica e dispositivo acessível à máquina |
BR122020013811A BR122020013811A8 (pt) | 2013-06-20 | 2014-06-20 | Aparelho para fornecer um regime de dosagem de proteína plasmática terapêutica |
BR122022000127A BR122022000127A8 (pt) | 2013-06-20 | 2014-06-20 | Método para fornecer um regime terapêutico de dosagem de proteína plasmática e aparelho que compreende instruções armazenadas no mesmo que são configuradas, quando executadas, para fazer com que o aparelho execute um procedimento para determinar um regime de dosagem |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015031856A BR112015031856A8 (pt) | 2013-06-20 | 2014-06-20 | Aparelho para prover um regime de dosagem de proteína plasmática terapêutica e dispositivo acessível à máquina |
BR122020013811A BR122020013811A8 (pt) | 2013-06-20 | 2014-06-20 | Aparelho para fornecer um regime de dosagem de proteína plasmática terapêutica |
Country Status (23)
Country | Link |
---|---|
US (1) | US20140379629A1 (pt) |
EP (3) | EP3010681B1 (pt) |
JP (4) | JP2016526542A (pt) |
KR (4) | KR102352133B1 (pt) |
CN (2) | CN105592973B (pt) |
AU (3) | AU2014287706B2 (pt) |
BR (3) | BR112015031856A8 (pt) |
CA (1) | CA2915472C (pt) |
CL (1) | CL2015003641A1 (pt) |
EA (1) | EA037962B1 (pt) |
ES (1) | ES2882832T3 (pt) |
GE (2) | GEP20186882B (pt) |
IL (3) | IL279313B (pt) |
MX (3) | MX2015017878A (pt) |
MY (2) | MY195911A (pt) |
NZ (1) | NZ715216A (pt) |
PH (1) | PH12015502800B1 (pt) |
PL (1) | PL3010681T3 (pt) |
SA (2) | SA521430246B1 (pt) |
SG (1) | SG11201510515YA (pt) |
UA (1) | UA118109C2 (pt) |
WO (1) | WO2015006033A1 (pt) |
ZA (1) | ZA201600100B (pt) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
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US10289953B2 (en) * | 2011-12-13 | 2019-05-14 | Koninklijke Philips N.V. | Dose optimization based on outcome quality |
US10083400B2 (en) | 2012-10-05 | 2018-09-25 | Diane R. MOULD | System and method for providing patient-specific dosing as a function of mathematical models updated to account for an observed patient response |
US10325687B2 (en) * | 2013-12-06 | 2019-06-18 | Bioverativ Therapeutics Inc. | Population pharmacokinetics tools and uses thereof |
CA2944909A1 (en) | 2014-04-04 | 2015-10-08 | Bloodworks | Routine laboratory and point-of-care (poc) testing for hemostasis |
US11062797B2 (en) * | 2014-10-10 | 2021-07-13 | Continuous Precision Medicine | Method and system for obtaining and using pharmacokinetic data in drug administration |
EP3298519A1 (en) * | 2015-04-09 | 2018-03-28 | Diane R. Mould | Systems and methods for patient-specific dosing |
WO2017136583A1 (en) * | 2016-02-02 | 2017-08-10 | Versartis, Inc. | Growth hormone treatment adherence system |
HUE065455T2 (hu) * | 2016-04-15 | 2024-05-28 | Takeda Pharmaceuticals Co | Eljárás és berendezés egy farmakokinetikai gyógyszer adagolási rendjének biztosítására |
JP6807015B2 (ja) * | 2016-06-13 | 2021-01-06 | ソニー株式会社 | 情報処理装置、情報処理方法、およびプログラム |
US10896749B2 (en) * | 2017-01-27 | 2021-01-19 | Shire Human Genetic Therapies, Inc. | Drug monitoring tool |
US20190365317A1 (en) * | 2017-02-01 | 2019-12-05 | Shire Human Genetic Therapies, Inc. | Physiological sensing and therapeutic administration system and method |
BE1027052A1 (fr) | 2019-02-14 | 2020-09-07 | Aardex Group | Procede d'assistance a la prise ou a l'acte d'un traitement therapeutique |
US10970651B1 (en) * | 2019-12-02 | 2021-04-06 | Sas Institute Inc. | Analytic system for two-stage interactive graphical model selection |
KR102420872B1 (ko) * | 2020-12-18 | 2022-07-14 | 포항공과대학교 산학협력단 | 강화학습과 약동-약력학 모델을 이용한 연속 약물 투여량 결정 방법 |
CN113053508A (zh) * | 2021-03-29 | 2021-06-29 | 深圳市科曼医疗设备有限公司 | 基于触控屏的交互控制方法及装置 |
Family Cites Families (14)
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JPH07124125A (ja) * | 1993-11-04 | 1995-05-16 | S R L:Kk | 薬物投与解析システム |
EP0796623B1 (de) * | 1996-03-20 | 2005-05-25 | Baxter Aktiengesellschaft | Pharmazeutisches Präparat zur Behandlung von Blutgerinnungsstörungen |
AU5219798A (en) * | 1996-12-09 | 1998-07-03 | Samuel David | Gpi-ceruloplasmin, analogs thereof, and methods of use |
RU2248215C2 (ru) * | 1999-05-11 | 2005-03-20 | Орто-Макнейл Фармасьютикал, Инк. | Фармакокинетическое и фармакодинамическое моделирование введения эритропоэтина |
US7860583B2 (en) * | 2004-08-25 | 2010-12-28 | Carefusion 303, Inc. | System and method for dynamically adjusting patient therapy |
US20040023211A1 (en) * | 2000-09-15 | 2004-02-05 | Kees Groen | System and method for optimizing drug theraphy for the treatment of diseases |
TWI236611B (en) * | 2003-02-01 | 2005-07-21 | Baxter Int | Medical data communication notification and messaging system and method |
EP1642607A1 (en) * | 2004-10-04 | 2006-04-05 | Sanofi-Aventis Deutschland GmbH | Dose display mechanism for a drug delivery device |
JP2006155071A (ja) * | 2004-11-26 | 2006-06-15 | Toshiba Sumiden Medical Information Systems Corp | 電子カルテ薬物療法指示実施システム |
US20060183786A1 (en) * | 2005-02-16 | 2006-08-17 | Chi Mei Foundation Hospital | Injectable long-acting analgesic composition comprising an ester derivative of ketorolac |
EP3703058A1 (en) | 2005-11-29 | 2020-09-02 | Children's Hospital Medical Center | A method of selecting a medication for a patient |
EP2286359A2 (en) * | 2008-03-27 | 2011-02-23 | Medtronic, Inc. | Method and system to define patient specific therapeutic regimens by means of pharmacokinetic and pharmacodynamic tools |
US8591454B2 (en) * | 2008-11-10 | 2013-11-26 | The Invention Science Fund I, Llc | Administering a therapeutic agent with more than one taggant |
EP4382170A2 (en) * | 2009-12-06 | 2024-06-12 | Bioverativ Therapeutics Inc. | Factor viii-fc chimeric and hybrid polypeptides, and methods of use thereof |
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2014
- 2014-06-20 GE GEAP201414039A patent/GEP20186882B/en unknown
- 2014-06-20 IL IL279313A patent/IL279313B/en unknown
- 2014-06-20 JP JP2016521871A patent/JP2016526542A/ja active Pending
- 2014-06-20 CN CN201480046279.5A patent/CN105592973B/zh active Active
- 2014-06-20 EP EP14823224.2A patent/EP3010681B1/en active Active
- 2014-06-20 US US14/311,113 patent/US20140379629A1/en not_active Abandoned
- 2014-06-20 MY MYPI2020003916A patent/MY195911A/en unknown
- 2014-06-20 CA CA2915472A patent/CA2915472C/en active Active
- 2014-06-20 UA UAA201600443A patent/UA118109C2/uk unknown
- 2014-06-20 CN CN202010499366.3A patent/CN111508557B/zh active Active
- 2014-06-20 EP EP21170633.8A patent/EP3879534A1/en active Pending
- 2014-06-20 MX MX2015017878A patent/MX2015017878A/es active IP Right Grant
- 2014-06-20 EA EA201690048A patent/EA037962B1/ru unknown
- 2014-06-20 BR BR112015031856A patent/BR112015031856A8/pt not_active Application Discontinuation
- 2014-06-20 EP EP17197995.8A patent/EP3309696A1/en not_active Withdrawn
- 2014-06-20 BR BR122020013811A patent/BR122020013811A8/pt not_active Application Discontinuation
- 2014-06-20 GE GEAP201414559A patent/GEP20196990B/en unknown
- 2014-06-20 PL PL14823224T patent/PL3010681T3/pl unknown
- 2014-06-20 KR KR1020217026984A patent/KR102352133B1/ko active IP Right Grant
- 2014-06-20 KR KR1020227001162A patent/KR102397974B1/ko active IP Right Grant
- 2014-06-20 NZ NZ715216A patent/NZ715216A/en unknown
- 2014-06-20 SG SG11201510515YA patent/SG11201510515YA/en unknown
- 2014-06-20 ES ES14823224T patent/ES2882832T3/es active Active
- 2014-06-20 WO PCT/US2014/043517 patent/WO2015006033A1/en active Application Filing
- 2014-06-20 KR KR1020167001142A patent/KR102296042B1/ko active IP Right Grant
- 2014-06-20 AU AU2014287706A patent/AU2014287706B2/en active Active
- 2014-06-20 BR BR122022000127A patent/BR122022000127A8/pt not_active Application Discontinuation
- 2014-06-20 MY MYPI2015704622A patent/MY176173A/en unknown
- 2014-06-20 KR KR1020227015723A patent/KR20220065097A/ko not_active Application Discontinuation
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2015
- 2015-12-16 CL CL2015003641A patent/CL2015003641A1/es unknown
- 2015-12-16 PH PH12015502800A patent/PH12015502800B1/en unknown
- 2015-12-17 SA SA521430246A patent/SA521430246B1/ar unknown
- 2015-12-17 SA SA515370289A patent/SA515370289B1/ar unknown
- 2015-12-17 IL IL243208A patent/IL243208B/en active IP Right Grant
- 2015-12-18 MX MX2023000359A patent/MX2023000359A/es unknown
- 2015-12-18 MX MX2020004112A patent/MX2020004112A/es unknown
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2016
- 2016-01-06 ZA ZA2016/00100A patent/ZA201600100B/en unknown
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2017
- 2017-12-07 AU AU2017272293A patent/AU2017272293B2/en active Active
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2019
- 2019-05-22 JP JP2019095949A patent/JP6813237B2/ja active Active
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2020
- 2020-04-21 AU AU2020202664A patent/AU2020202664B2/en active Active
- 2020-05-21 IL IL274848A patent/IL274848A/en active IP Right Grant
- 2020-12-11 JP JP2020205945A patent/JP7060291B2/ja active Active
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2022
- 2022-04-11 JP JP2022065039A patent/JP7398031B2/ja active Active
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