KR102267927B1 - Tor 키나제 억제제를 사용한 전립선암의 치료 - Google Patents
Tor 키나제 억제제를 사용한 전립선암의 치료 Download PDFInfo
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- KR102267927B1 KR102267927B1 KR1020207026267A KR20207026267A KR102267927B1 KR 102267927 B1 KR102267927 B1 KR 102267927B1 KR 1020207026267 A KR1020207026267 A KR 1020207026267A KR 20207026267 A KR20207026267 A KR 20207026267A KR 102267927 B1 KR102267927 B1 KR 102267927B1
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261715510P | 2012-10-18 | 2012-10-18 | |
| US61/715,510 | 2012-10-18 | ||
| PCT/US2013/065363 WO2014062878A2 (en) | 2012-10-18 | 2013-10-17 | Treatment of cancer with tor kinase inhibitors |
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| EP2945636B1 (en) | 2013-01-16 | 2017-06-28 | Signal Pharmaceuticals, LLC | Substituted pyrrolopyrimidine compounds, compositions thereof, and methods of treatment therewith |
| US9737535B2 (en) | 2014-04-16 | 2017-08-22 | Signal Pharmaceuticals, Llc | Methods for treating cancer using TOR kinase inhibitor combination therapy comprising administering substituted pyrazino[2,3-b]pyrazines |
| NZ629796A (en) | 2014-07-14 | 2015-12-24 | Signal Pharm Llc | Amorphous form of 4-((4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7h-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-3-methoxy-n-methylbenzamide, compositions thereof and methods of their use |
| AU2015289929A1 (en) | 2014-07-14 | 2017-03-02 | Signal Pharmaceuticals, Llc | Methods of treating a cancer using substituted pyrrolopyrimidine compounds, compositions thereof |
| JP6964343B2 (ja) * | 2015-11-20 | 2021-11-10 | フォーマ セラピューティクス，インコーポレイテッド | ユビキチン特異的プロテアーゼ１阻害剤としてのプリノン |
| EP3641772B1 (en) | 2017-06-22 | 2023-08-02 | Celgene Corporation | Treatment of hepatocellular carcinoma characterized by hepatitis b virus infection |
| CN110403943B (zh) * | 2019-08-19 | 2022-05-17 | 陕西科技大学 | Cc-115在制备抗真菌药物中的应用及其药物组合物 |
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| US20070238745A1 (en) * | 2006-04-07 | 2007-10-11 | University Of South Florida | PI3K-Akt Pathway Inhibitors |
| ES2383370T3 (es) | 2006-10-19 | 2012-06-20 | Signal Pharmaceuticals Llc | Compuestos de heteroarilo, sus composiciones y uso de los mismos como inhibidores de proteína quinasa |
| EP2457913B1 (en) * | 2006-10-19 | 2017-04-19 | Signal Pharmaceuticals, LLC | Heteroaryl compounds, compositions thereof, and methods of treatment therewith |
| EP2349984A1 (en) * | 2008-10-17 | 2011-08-03 | Merck & Co. | Combination therapy |
| JP2013508456A (ja) * | 2009-10-26 | 2013-03-07 | シグナル ファーマシューティカルズ， エルエルシー | ヘテロアリール化合物の合成方法および精製方法 |
| US20120238562A1 (en) * | 2011-03-09 | 2012-09-20 | Cedars-Sinai Medical Center | Treatment of cancer by targeting molecules that influence mst1/stk4 signaling |
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| US20100216781A1 (en) * | 2008-10-27 | 2010-08-26 | Sophie Perrin-Ninkovic | mTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE mTOR/PI3K/AKT PATHWAY |
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