KR102223447B1 - Composition for scalp and hair cosmetic - Google Patents

Abstract

The present invention relates to a cosmetic composition for scalp and hair and, more specifically, to a cosmetic composition for scalp and hair, comprising: a Glycine soja embryo extract; a horseradish extract; copper tripeptide-1; hexapeptide-2; and biotin as active ingredients. The cosmetic composition for scalp and hair according to the present invention is capable of alleviating hair troubles such as hair breakage, gloss loss of hair, and splitting thereof, and scalp troubles such as hair loss, itchiness, dandruff, excessive sebum secretion, scalp odor, and inflammatory diseases.

Description

Composition for scalp and hair cosmetic

The present invention relates to a cosmetic composition for scalp and hair, and in more detail, it contains dolkong embryo extract, horseradish extract, copper tripeptide-1, hexapeptide-2 and biotin as active ingredients, significantly reducing hair and scalp troubles. It relates to a cosmetic composition for improving scalp and hair.

The scalp is a specialized skin tissue covered with hair, and the most common diseases caused by scalp abnormalities include hair loss, dandruff, itching, etc. It appears easily during daily life, but treatment is not easy. In particular, in the case of a sensitive scalp, irritation and inflammation such as itchiness or itching of the scalp are induced, causing further problems.

When looking at the cause of scalp trouble, it has been reported that the fatty acid produced by proliferation of Pityrosporum ovale, a scalp flora, to decompose lipids acts as an irritant, causing excessive stratum corneum formation and itching. . In addition, lipid peroxide is produced by oxidation reactions caused by ultraviolet rays or contaminated air, and acts as an irritant, causing scalp problems. In addition, scalp problems may occur due to an increase in keratin metabolism, an increase in sebum secretion function, and hormone abnormalities caused by stress or constitution.

In addition, when the scalp health is not good as described above, the hair is also weakened and thinner, and problems such as loss of gloss occur.

Therefore, research to improve the condition of the scalp and hair has been continued.

KR 10-1397160 B1 KR 10-1637466 B1 KR 10 2141574 B1

Accordingly, an object of the present invention is to include hair bean germ extract, horseradish extract, copper tripeptide-1, hexapeptide-2, and biotin as active ingredients, such as hair breakage, loss of shine, cracking, and hair problems such as hair loss, itchiness, It is to provide a cosmetic composition for scalp and hair that can improve scalp problems such as dandruff, excessive sebum secretion, scalp odor, and scalp inflammation.

Another object of the present invention is to provide a cosmetic composition for scalp and hair that can maximize the absorption rate in the scalp and hair by stabilizing the active ingredient with nanoliposomes.

The cosmetic composition for scalp and hair of the present invention for achieving the above object is characterized in that it comprises as an active ingredient a dolkong embryo extract, wasabi extract, copper tripeptide-1, hexapeptide-2 and biotin.

It characterized in that it further comprises butylene glycol, 1,2-hexanediol, and purified water.

The dolphin germ extract 0.1 to 1% by weight, horseradish extract 0.05 to 1% by weight, copper tripeptide-1 0.01 to 0.1% by weight, hexapeptide-2 0.001 to 0.01% by weight, biotin 0.001 to 0.01% by weight, butylene glycerol It is characterized by consisting of 15 to 25% by weight of Cole, 1 to 3% by weight of 1,2-hexanediol, and the remainder of purified water.

The active ingredient is stabilized with liposomes, and the average particle diameter of the liposome is 50 to 70 nm.

The cosmetic composition for scalp and hair according to the present invention has the advantage of improving hair troubles such as hair breakage, loss of shine, and cracking, and scalp troubles such as hair loss, itchiness, dandruff, excessive sebum secretion, scalp odor, and inflammatory diseases. .

Hereinafter, the present invention will be described in detail.

The cosmetic composition for hair and scalp according to the present invention is for improvement of hair troubles and scalp troubles, and the hair troubles include hair breakage, loss of shine, and cracks, and the scalp troubles refer to hair loss, itchiness, dandruff, and excessive sebum. It includes secretion, scalp odor, and scalp inflammation.

The cosmetic composition for hair and scalp according to the present invention is characterized in that it comprises as an active ingredient a dolkong embryo extract, wasabi extract, copper tripeptide-1, hexapeptide-2 and biotin.

The Soybean Germ Extract contains a large amount of polyamine, which is an essential energy source in breast milk, to maintain cell function and provide vitality, promote the growth of dermal papilla cells, and promote the growth of hair follicles and hair, and regeneration of collagen. Do the mechanics. In addition, it plays a role in restoring hair damage through abundant cations. In addition, the dolkong germ extract is rich in polyphosphate and vitamin E, so it helps to calm and moisturize the scalp.

The reason why the dolkong embryo is used in the present invention is that it contains more active ingredients such as polyamine and polyphosphate than dolkong.

The method of preparing the dolkong germ extract is not limited, and various extraction methods known in the field to which this technology belongs can be applied, and as a solvent, water, alcohol having 1 to 6 carbon atoms, hexane, ethyl acetate, and their At least one selected from the group consisting of mixed solvents may be used.

Wasabia Japonica Extract contains a large amount of isosaponarin, which promotes the expression of growth factors, promotes the expression of vascular endothelial growth factor (VEGF), which is effective for improving blood flow, and promotes the growth of dermal papilla cells. , It inhibits the growth of various harmful microorganisms due to its excellent antibacterial and anti-inflammatory activity, and plays a role in inhibiting enzyme activity, which is the cause of scalp odor. That is, the scalp odor and body odor are caused by decomposition of fatty acids by lipase, etc., and the wasabi extract has the effect of reducing the activity of lipase and promoting the removal of odor-causing gases.

The method of preparing the wasabi extract is not limited, and various extraction methods known in the field to which this technology belongs can be applied to one or more of the roots, leaves, and stems of wasabi. One or more selected from the group consisting of 1 to 6 alcohol, hexane, ethyl acetate, and mixed solvents thereof may be used.

Copper Tripeptide-1 is a component that promotes regeneration of blood vessels, thereby stimulating the formation of hair follicles, increasing the supply of nutrients for hair growth, promoting hair growth, and increasing the thickness of the hair. To induce. In addition, copper ions enhance the formation of hair follicles by promoting VEGF expression in various cells. In addition, it relieves the inflammatory response and improves the dermal density.

The hexapeptide-2 is a peptide that promotes the secretion of growth hormone, transmits various signals related to growth through GH secretagoguereceptor (GHSR), increases the secretion of growth hormone, and activates the hair regrowth signal. . In addition, by increasing the biosynthesis of collagen, hair follicle shrinkage, hair softening, and hair loss are alleviated.

Biotin is a coenzyme that helps metabolic processes in our body, promotes cell growth, and strengthens hair.

Therefore, the cosmetic composition for scalp and hair comprising the above-described dolkong embryo extract, wasabi extract, copper tripeptide-1, hexapeptide-2 and biotin as active ingredients, prevents hair loss, promotes hair growth, and reduces scalp odor. It removes, relieves scalp inflammation, suppresses dandruff production, relieves itching, and has the advantage of improving hair breakage, loss of shine, and cracking.

At this time, the cosmetic composition for scalp and hair according to the present invention may further include butylene glycol, 1,2-hexanediol, and purified water in addition to the above-described active ingredients.

The butylene glycol (1,3-bytylene glycol) is an ingredient made from a material derived from fatty acids extracted from fermented sugar cane, and is effective for moisturizing the skin, and as a solvent, as well as for the active ingredient to penetrate the scalp well. It also acts as a vehicle.

The 1,2-hexanediol (1,2-hexandiol) is excellent in antiseptic effect and also provides excellent moisturizing power.

The purified water is included as a solvent.

In addition, the composition of the present invention as described above, based on the total 100% by weight, as an active ingredient, dolphin germ extract 0.1 to 1% by weight, horseradish extract 0.05 to 1% by weight, copper tripeptide-1 0.01 to 0.1% by weight , Hexapeptide-2 contains 0.001 to 0.01% by weight, biotin 0.001 to 0.01% by weight, and incidentally butylene glycol 15 to 25% by weight, 1,2-hexanediol 1 to 3% by weight, and the remainder of purified water This is because, if each component is out of the above-described blending ratio, it does not exhibit the required sufficient efficacy, as well as an excessive amount, resulting in poor safety.

In addition, the active ingredients of the cosmetic composition for scalp and hair according to the present invention, dolphin embryo extract, horseradish extract, cappertripeptide-1, hexapeptide-2, and biotin are in a liposome-stabilized state, and the average particle diameter of the liposome is It is preferably 50 to 70 nm.

This is not only for stabilizing the active ingredient, but also to increase the penetration rate of the active ingredient into the scalp and hair through nano-sized liposomes, so as to have more excellent scalp troubles and improvement effects of hair troubles.

The liposome of the present invention may be formed by a mixture comprising the above-described stone bean germ extract, horseradish extract, copper tripeptide-1, hexapeptide-2, and active ingredients including biotin, polyols, phospholipids, oil and water, etc. And, the preparation of the liposome is performed according to a general liposomeization technique.

In other words, the constituents are classified into a composition belonging to each dispersed phase and a continuous phase, put in each container, melted at a certain temperature, and then the components corresponding to the continuous phase are evenly dispersed, and the active ingredients are evenly dispersed in the purified water corresponding to the dispersed phase. Let it. And the dispersed phase and the continuous phase are homogenized for 3 to 5 times at 1,000 bar using a high-speed mixer, and then the homogenized solution is cooled and defoamed to prepare liposomes, and it is natural that the implementation is not limited.

In addition, the cosmetic composition according to the present invention may add additives that can be blended into the cosmetic composition for general scalp and hair, if necessary. For example, stabilizers, solubilizers or emulsifiers, vitamins, surfactants, thickeners, pH adjusters, preservatives, antioxidants, pigments, flavors, or combinations thereof may further be added.

The cosmetic composition according to the present invention may be prepared in any formulation conventionally prepared in the technical field to which cosmetics for scalp and hair belong. For example, it can be prepared in a variety of formulations such as solutions, suspensions, emulsions, pastes, gels, creams, lotions, shampoos, surfactant-containing cleansing, tonics, and scaling. For example, hair tonic, hair conditioner, hair essence, hair lotion, hair nutrition lotion, hair shampoo, hair rinse, hair treatment, hair cream, hair nutrition cream, hair moisture cream, hair massage cream, hair wax, hair aerosol , Hair pack, hair nutrition pack, hair soap, hair cleansing foam, hair oil, hair dryer, hair preservation treatment agent, hair dye, hair wave agent, hair bleaching agent, hair gel, hair glaze, hairdresser, hair lacquer, hair moisturizer, It may include a formulation of hair mousse or hair spray.

In addition, the composition of the present invention can be used by a method such as direct application or dispersion to the hair or scalp. The hair to which the composition of the present invention is applied includes hair roots and hair follicles of the head, hair and eyelashes and outer lashes, beard, armpits, pubic hair, and all areas having hair roots and hair follicles throughout the body.

Hereinafter, the present invention will be described in more detail through specific embodiments of the present invention.

(Example 1)

Dolbean embryos and wasabi roots were dried and pulverized, respectively, and 500 g of 50% ethanol aqueous solution was added to 100 g of each sample, followed by reflux extraction at 40° C. for 5 hours. Then, the sample and the extract were separated by centrifugation for 20 minutes at 8,000 rpm and 15° C. using a centrifuge (Supra 22K, Hanil, Korea). The separated extract was filtered through a 0.45 μm filter to obtain a filtrate, and the filtrate was freeze-dried at -80°C for 48 hours using a freeze dryer after pretreatment of freezing at -21°C. An extract of and wasabi root extract were obtained.

And to prepare a cosmetic composition comprising the active ingredients dolphin germ extract, horseradish extract, copper tripeptide-1, hexatripeptide-1, and biotin in the composition ratio shown in Table 1 below.

Composition ratio of Example 1 division CAS. NO. Content (% by weight) Dole Bean Germ Extract 0.500 Wasabi extract 0.120 Copper Tripeptide-1 89030-95-5 0.050 Hexapeptide-2 87616-84-0 0.005 Biotin 58-85-5 0.005 Butylene Glycol 107-88-0 20.000 1,2-hexanediol 6920-22-5 2.000 Purified water 7732-18-5 to 100

(Example 2)

In Table 2 below, the water phase was put into a vacuum emulsifying tank and heated to 75°C, and separately, the oil phase was added to an oil phase melting tank and heated to 75°C. Then, the oil phase was added to the water phase, and the mixture was stirred for 8 minutes at a speed of 2,500 rpm using a homomixer while maintaining the temperature at 75° C. to form bulky spherical liposomes by first emulsification, and then cooled to 50° C. , Using a homomixer, the active ingredient was enclosed in a bulky spherical liposome by stirring at a speed of 2,000 rpm. Thereafter, a bulky spherical liposome was put into a high-pressure emulsifier, treated three times at 1,000 bar pressure, and then subjected to secondary emulsification to prepare a cosmetic composition containing an active ingredient stabilized with nanoliposomes.

Composition ratio of Example 2 division CAS. NO. Content (% by weight) Award Purified water 7732-18-5 to 100 Dole Bean Germ Extract 0.500 Wasabi extract 0.120 Copper Tripeptide-1 89030-95-5 0.050 Hexapeptide-2 87616-84-0 0.005 Biotin 58-85-5 0.005 Paid part Butylene Glycol 107-88-0 20.000 1,2-hexanediol 6920-22-5 2.000 lecithin 5.000 Ceramide 1.000 cholesterol 0.500 Caprylic/Capric Triglyceride 5.000

(Comparative Example 1)

Prepared in the same manner as in Example 1, but did not use the dolphin germ extract and horseradish extract as active ingredients.

(Comparative Example 2)

It was prepared in the same manner as in Example 1, but only 0.68% by weight of dolkong germ extract was used as an active ingredient.

(Comparative Example 3)

It was prepared in the same manner as in Example 1, but only the wasabi extract was used in an amount of 0.68% by weight as an active ingredient.

(Test Example 1)

The average particle diameter of the cosmetic composition prepared in Example 2 was tested. The results were shown in Table 3 below.

The test of the average particle diameter was requested by an external organization, Koptri. For the test, 0.2 g of the provided sample was diluted with 20 g of DI water, and then analyzed with Zeta-potintial & Particle size Analyzer ELSZ-2000ZS of Photal OTSUKA ELECTRONICS, and the average value was shown as a result after the test over three times.

Test Example 1 result Sample name Test Items unit Test Methods Test temperature Test result Example 2 Average particle diameter nm ISO 22412 25℃ 62.0

As can be seen in Table 3, it was confirmed that the average particle diameter of the liposome in the cosmetic composition prepared according to Example 2 according to the present invention was 62.0 nm.

(Test Example 2)

The effect of inhibiting dandruff bacteria of Examples 1 and 2 was tested.

The anti-dandruff effect was tested for antibacterial activity against Malassezia (Malassezia furfur ATCC 12078), which is a dandruff bacterium. As a control group, none of the experimental samples were used, and the dandruff bacteria were inoculated and cultured. The Malassezia bacteria were plated on SDA (Sabouraud Dextrose Agar) medium and inoculated, and a sample was applied to the center of the plate medium, followed by incubation at 30±1° C. for 2 to 3 days.

W = (T-D) / 2

(W: width of the basin (nm), T: total diameter of the sample and microbial basin (nm), D: diameter of the sample (nm))

The size of the microbial basin was calculated according to the above equation, and the experiment was carried out three times each to measure the results, and the average values are shown in Table 4 below.

Test Example 2 result Test strain sample T(nm) D(nm) W(nm) Malassezia furfur
(ATCC 12078) Example 1 75 20 27.5 Example 2 76 20 28 Comparative Example 1 20 20 0 Comparative Example 2 22 20 One Comparative Example 3 52 20 13

As shown in Table 4, it was confirmed that the compositions of Examples 1 and 2 of the present invention had excellent antibacterial activity against dandruff bacteria.

(Test Example 3)

The anti-inflammatory effect of Examples 1 and 2 was tested.

The anti-inflammatory effect was measured by the lipoxygenase inhibitory effect. Lipoxygenase (5-LO) is an enzyme that acts in the first reaction of the biosynthesis of leukotriene, which is involved in various inflammatory and allergic diseases. Therefore, the anti-inflammatory effect was confirmed by measuring the inhibitory effect of lipoxygenase using SLO (soybean lipoxygenase), which is structurally and mechanically similar to 5-LO. The process of measuring the lipoxygenase inhibitory effect is as follows. Samples were added to 1 ml of 1 mM linoleic acid at concentrations of 0.3, 1.3 and 2.5% (v/v), and 0.9 ml of 50,000 units/ml lipoxygenase dissolved in 0.1 M sodium phosphate buffer was added, and in a water bath at 25°C It was allowed to react for 15 minutes. 0.5 ml of 20% (w/v) trichloroacetic acid was added to terminate the reaction, and 1 ml of 0.6% (w/v) TBA was added, followed by color development in boiling water for 15 minutes. Then, it was cooled in ice water for 2 minutes, 2 ml of n-butanol was added and mixed with shaking, followed by centrifugation at 3,500 rpm for 5 minutes. The upper layer (n-butanol layer) was taken and the absorbance was measured at 535 nm to evaluate the anti-inflammatory effect (%). As a control, a solvent was used instead of the sample. The blank used 0.1M sodium phosphate buffer instead of lipoxygenase. The lipoxygenase inhibitory effect was determined by the following formula, and the results are shown in Table 5 below.

Inhibitory effect (%)=[1-(absorbance of sample/absorbance of control)]×100

Test Example 3 result (%) Concentration (%, v/v) 0.3 1.3 2.5 Example 1 7.2 25.3 50.0 Example 2 7.5 27.8 55.6 Comparative Example 1 0.1 0.2 0.2 Comparative Example 2 0.2 1.5 3.2 Comparative Example 3 3.2 16.3 28.5

As shown in Table 5, it was confirmed that Examples 1 and 2 of the present invention showed excellent anti-inflammatory effects.

(Test Example 4)

The dermal papilla cell activity of Examples 1 and 2 was tested.

The dermal papilla cells were diluted with M199 culture solution containing 10% FBS to a concentration of 2×10 ⁴ /ml, put 5 ml each in a 60 mm culture container, and cultured in an incubator at 37°C for 24 hours. The next day, the culture medium containing FBS was removed, the culture medium containing no FBS and the culture medium containing the sample were exchanged and cultured for 24 hours, and then radiation-labeled thymidine was added 10 μCi per culture dish. The time was further incubated. The cells after the culture were washed three times with a phosphate buffer solution, and washed once with 5% trichloroace-tic acid. The cells were dissolved in 0.1% sodium dodecylsulfonate and 0.5N sodium hydroxide solution, mixed with a scintillation cocktail, and the amount of radioisotope was measured using a beta-counter. Cellular activity was compared to the control group, compared to the control group, compared to how much radiolabeled thymidine uptake into the cells was evaluated. And the results are shown in Table 6 below.

Test Example 4 Results division density Activity (%) Control 100 Example 1 10ppm 109 100ppm 122 1000ppm 129 Example 2 10ppm 112 100ppm 132 1000ppm 138 Comparative Example 1 10ppm 102 100ppm 107 1000ppm 110 Comparative Example 2 10ppm 104 100ppm 110 1000ppm 114 Comparative Example 3 10ppm 105 100ppm 111 1000ppm 116

As can be seen in Table 6, it was confirmed that Examples 1 and 2 of the present invention exhibited very excellent dermal papilla cell activity.

(Test Example 5)

The scalp odor removal effect of Examples 1 and 2 was tested.

Caproic acid and caprylic acid were used as the causative components of the scalp odor, so that caproic acid 0.1% by weight, caprylic acid 0.1% by weight and the balance DPG were prepared. Then, a 10×10cm test cotton cloth was placed in a 2L beaker, and the above-mentioned Ichiwon (diluted with 1% ethanol) was sprayed 4 times, and the upper part was covered with foil. After allowing the beaker to stand at room temperature for 5 minutes, 0.5 ml of the sample was sprayed onto the cotton cloth in the beaker, and the upper portion of the beaker was covered with foil, and then left at room temperature for 10 minutes. After 10 minutes, a hole having a diameter of 1 cm was made in the foil of the beaker and the smell was smelled to evaluate off-flavor. At this time, purified water was used as a control.

The sensory evaluation was conducted on 20 men and women in their 20s to 40s, and the criteria for the sensory evaluation were 1 point: no off-flavor, 2 points: weak off-odor, 3 points: slightly strong off-odor, 4 points: strong off-odor Yes, 5 points: It was determined that there was a very strong off-flavor.

And the results are shown as an average value in Table 7 below.

Test Example 5 result division Example 1 Example 2 Comparative Example 1 Comparative Example 2 Comparative Example 3 Control medium 1.90 1.71 4.41 4.23 3.25 4.70

As shown in Table 7 above, it was confirmed that Examples 1 and 2 of the present invention can alleviate scalp odor.

(Test Example 6)

The effect of improving scalp troubles of Examples 1 and 2 was tested.

Subjects with symptoms of scalp itching, dandruff and excessive sebum secretion were selected. The subjects were 50 adult men and women aged 35 to 50 years old, divided into five groups, once a day for 3 months, after washing 5 ml of the compositions of Examples 1 and 2 and Comparative Examples 1, 2, and 3 above. , The scalp and hair were evenly applied and the results were observed.

To determine the effect, the degree of relief of itching, dandruff, and excessive sebum secretion and the feeling of irritation were evaluated in five stages as an evaluation scale, and the average was taken, and the score was given in units of 1 point according to the stage with a perfect score of 5 points. .

And the results are shown in Table 8 below.

Test Example 6 Results division Example 1 Example 2 Comparative Example 1 Comparative Example 2 Comparative Example 3 Itching 4.2 4.3 1.5 1.5 1.8 dandruff 4.0 4.2 1.7 1.6 2.5 Excessive sebum secretion 3.8 4.0 1.8 1.5 2.6 Stimulation evaluation 1.0 1.0 1.0 1.0 1.0 1: There is no effect or irritation at all. 2: There is no effect or stimulation.
3: The effect or stimulation is moderate. 4: There is an effect or irritation.
5: There is a lot of effect or stimulation.

As shown in Table 9, in Examples 1 and 2 of the present invention, it was confirmed that it was excellent in alleviating scalp troubles such as itching, dandruff, and excessive sebum secretion, and it was confirmed that there was no irritation.

(Test Example 7)

The alopecia improvement effect of Examples 1 and 2 was tested.

Subjects with hair loss symptoms were selected. The subjects were 50 adult men and women aged 35 to 50 years old, divided into four groups, once a day for 3 months, after washing 5 ml of the compositions of Examples 1 and 2 and Comparative Examples 1, 2, and 3 above. , The scalp and hair were evenly applied and the results were observed.

To determine the effect, the daily average amount of hair loss, visual findings and subjective symptom improvement at the time of hair removal were evaluated in five stages as an evaluation scale, and the overall degree of improvement was taken as the average of the evaluation scale, and the score was scored as a perfect score of 5 points. Therefore, it was given in units of 1 point.

And the results are shown in Table 9 below.

Test Example 7 result division Example 1 Example 2 Comparative Example 1 Comparative Example 2 Comparative Example 3 Visually 3.5 3.7 2.1 2.2 2.3 Subjective symptoms 3.9 4.0 2.3 2.4 2.5 Hair loss during hair removal 3.6 3.8 2.2 2.1 2.2 Comprehensive improvement 3.7 3.9 2.3 2.2 2.4 1: deterioration, 2: constant, 3: slight improvement, 4: moderate improvement, 5: much improvement

As shown in Table 9, it was confirmed that Examples 1 and 2 of the present invention showed an effect of improving alopecia.

(Test Example 8)

The effect of improving hair troubles of Examples 1 and 2 was tested.

Subjects with symptoms of hair breakage, loss of shine, and cracking were selected. The subjects were 50 adult men and women aged 35 to 50 years old, divided into four groups, and once a day for 3 months, after washing the hair with 5 ml of the compositions of Examples 1 and 2 and Comparative Example 1, scalp and hair Evenly applied to the surface and observed the results.

For the evaluation of the effect, the degree of improvement of hair breakage, loss of shine, and cracking was evaluated in 5 stages as an evaluation scale, and the average was taken, and the score was given in units of 1 point according to the stage with a perfect score of 5 points.

And the results are shown in Table 10 below.

Test Example 8 result division Example 1 Example 2 Comparative Example 1 Comparative Example 2 Comparative Example 3 burnish 4.2 4.2 3.1 3.2 3.1 offshoot 4.3 4.3 3.3 3.4 3.2 Hair breakage 4.2 4.4 3.3 3.5 3.2 1: a lot worse, 2: a little worse, 3: moderate, 4: a little improvement, 5: a lot of improvement

As shown in Table 10, it was confirmed that Examples 1 and 2 of the present invention improve hair problems such as gloss, cracking, and hair breakage.

In the above, the present invention has been described in detail only for the described embodiments, but it is obvious to those skilled in the art that various modifications and modifications are possible within the scope of the technical idea of the present invention, and it is natural that such modifications and modifications belong to the appended claims.

Claims (4)

delete delete Including stone bean germ extract, horseradish extract, copper tripeptide-1, hexapeptide-2 and biotin as active ingredients,
Butylene glycol, 1,2-hexanediol, lecithin, ceramide, cholesterol, caprylic/capric triglyceride and purified water are further included,
The blending ratio is,
The dolkong germ extract 0.5% by weight, horseradish extract 0.12% by weight, copper tripeptide-1 0.05% by weight, hexapeptide-2 0.005% by weight, biotin 0.005% by weight, butylene glycol 20% by weight, 1,2-hexane Diol 2% by weight and the balance of purified water,
A cosmetic composition for scalp and hair, characterized in that it has antibacterial activity and lipoxygenase inhibitory activity against Malassezia bacteria, which are dandruff bacteria (Malassezia furfur ATCC 12078).
The method of claim 3,
The active ingredient is stabilized with liposomes,
Cosmetic composition for scalp and hair, characterized in that the average particle diameter of the liposome is 50 ~ 70nm.