KR102222361B1 - Cosmetic composition for whitening or improving the facial color containing herb extracts - Google Patents

Abstract

The present invention relates to a composition for whitening or improving complexion. The composition comprising the extract of ginseng, baby chickadee, broiler chicken, peony, licorice, golden, angelica or a mixture thereof according to the present invention as an active ingredient inhibits the synthesis of melanin and exhibits a whitening effect, thereby making it a cosmetic composition for whitening or improving complexion Can be used.

Description

Cosmetic composition for whitening or improving the facial color containing herb extracts}

The present invention relates to a cosmetic composition for whitening or improving complexion comprising an herbal extract, and more particularly, one or more extracts selected from the group consisting of ginseng, baby chickadee, broiler, peony, licorice, golden and angelica, or fractions thereof It relates to a cosmetic composition for whitening or improving complexion comprising as an active ingredient.

Melanin, which determines the color of a person's skin, is produced in melanocytes. Specifically, melanin is a dark brown pigment formed by polymerization and oxidation reactions by enzymes such as tyrosinase present in melanocytes using tyrosine, an amino acid present in a living body, as a substrate. The melanin thus formed moves to epidermal cells called keratinocytes through dendritic processes of melanocytes. Melanin that has migrated to keratinocytes can be removed by releasing them together from the skin as the keratinocytes break away from the epidermis. However, since there is no enzyme that degrades melanin in the living body, melanin once formed is not degraded in the living body. Therefore, in order to brighten the skin, it can be said that suppressing the production of melanin is the key.

The necessity of research on whitening agents as cosmetics is gradually increasing as the standard of living in the Eastern world, which emotionally prefers white skin, is improved, and skin blackening is recognized as skin aging due to ultraviolet rays. Accordingly, substances exhibiting tyrosinase inhibitory activity, such as ascorbic acid, hydroquinone, glutathione, and arbutin, have been formulated and used in cosmetics and pharmaceuticals (Patent Document 1 and 2) Most of these are ineffective due to insufficient effect or unstable in formulation. In particular, compounds such as hydroquinone exhibit a strong bleaching action and have skin sensitization by themselves, which can cause skin allergies, etc., and exhibit side effects such as causing vitiligo by changing the normal skin function, so safety aspects for the skin Its use is limited in.

In addition, even if the substance inhibits the activity of tyrosinase as described above, if such substances act on keratinocytes, which are keratinocytes, to increase the production of factors that promote the biosynthesis of melanin, as a result, the whitening effect is weakened or rather Since it can have an adverse effect, simply an inhibitor of tyrosinase activity cannot be regarded as a good whitening agent. Accordingly, many tyrosinase inhibitors have been developed, but most of them are known to exhibit no excellent whitening effect.

Under this background, the present inventors conducted research on substances that are non-toxic and excellent in skin condition improvement effect from natural resources, and thus the group consisting of ginseng, baby chickadee, broiler chicken, peony, licorice, golden and angelica. It was found that at least one herbal extract selected from the extract exhibits an inhibitory effect on melanin synthesis, and a cosmetic composition for whitening or improving complexion using the same has been completed.

[Patent Literature]

(Patent Document 1) Korean Registered Patent Publication No. 10-0923141

(Patent Document 2) Korean Registered Patent Publication No. 10-0921947

It is an object of the present invention to provide a cosmetic composition for whitening or improving complexion, comprising as an active ingredient one or more extracts or fractions thereof selected from the group consisting of ginseng, baby chickadee, broiler, peony, licorice and angelica. To provide.

In order to solve the above problems, as an embodiment of the present invention, characterized in that it comprises as an active ingredient one or more extracts or fractions thereof selected from the group consisting of ginseng, Arabidopsis, broiler, peony, lichen, golden and angelica. It provides a cosmetic composition for whitening or improving complexion.

In another embodiment of the present invention, it provides a cosmetic composition for whitening or improving complexion, comprising a mixed extract of ginseng, baby chickadee, broiler, peony, licorice, golden and angelica, or a fraction thereof as an active ingredient.

In another embodiment of the present invention, the mixing ratio of the ginseng, baby chickadee, broiler, peony, licorice, golden, and angelica is 10 to 30: 10 to 30: 10 to 20: 10 to 20: 10 to 20 by weight : 10 to 20: It may be 3 to 15.

In another embodiment of the present invention, the mixing ratio of the ginseng, baby chickadee, broiler, peony, licorice, golden, and angelica is 15 to 20: 15 to 20: 15: 15: 12 to 15: 12 to 15 based on weight. : It may be 6 to 10.

Ginseng (Ginseng Radix) of the present invention refers to the root of a perennial plant belonging to the genus Panax (Araliaceae). Preferably, ginseng may be dried. Ginseng is a representative medicinal plant and has a very slow growth rate, so it takes 4-6 years of cultivation to obtain sufficient medicinal ingredients. The main active ingredient of ginseng is known as saponin or ginsenosides, a complex carbohydrate (alcohol or a complex of phenol and sugar). These components excite and sedate the central nervous system, regulate metabolism, reduce blood sugar, improve muscle activity, excite the endocrine system, and maintain the concentration of hormones appropriately. In particular, saponins of ginseng are mostly triterpenoid dammaran saponins, and are unique saponins that exist only in plants of the genus Ginseng. Plant saponin has a hemolytic action, and in particular, the saponin component of ginseng is a neutral glycoside with little toxicity.

Baby parts of the present invention ( Typha angustifolia ) means a perennial plant belonging to the Typhaceae family. In the present invention, in particular, the ear portions of the baby parts can be dried and used. The larvae grow in the waters of rivers or ponds, their height is about 1.5m, the rhizomes are long sideways, and the stems stand upright in a cylindrical shape. Leaves are linear, about 80~100cm long, and the bottom surrounds the stem. In the flower, the male and female ears run apart. The flower has white hairs at the bottom and has no corolla. Male flower has 3 anthers and pollen is yellow. The pistil head is linear. Soft leaves are used to weave cushions, and pollen is called pohwang (蒲黃) and is used for hemostasis, anti-inflammatory urine, and tongyeong in oriental medicine.

Broiler of the present invention refers to the bark of the broiler tree ( Cinnamomum cassia ) belonging to the Lauraceae family. In the present invention, broiler chicken can be used after drying. The bark of broilers is harvested between August and October and dried in the dark moon for use. It has a spicy, sweet taste and is hot in nature, so it is a medicinal that helps our body communicate well. It has central inhibition, soothing, pain relief, fever, coronary artery blood flow increase, skin fungal inhibition, and weakness in the back and knees, lack of energy, and urine. It has been used to treat diarrhea, vomiting, menstrual impurities, menstrual pain, postpartum blood abdominal pain, boils, skin ulcers, and limb paralysis pain.

The peony of the present invention is a perennial plant belonging to the Ranunculaceae family, Paeonia albiflora ) refers to the root. Preferably, a dry peony may be used. Peony is used as a pain reliever, antipyretic or diuretic. Main ingredients include pheonoside, paeoniflorin, β-sitosterol, paeonine, gallotanin, benzoic acid, astragalin, etc. There is this.

Maekmundong of the present invention is a perennial seconds maekmundong (Ophiopogon belonging to Liliaceae (Liliaceae) japonicus ) means the tuber. Desirably, a dry one may be used as the lichen. Liqueuritis is particularly good for diabetes, and is used as an anti-inflammatory, diuretic, antibacterial, antipyretic, tonic, antitussive expectorant and cardiac.

The gold of the present invention refers to the root of the perennial plant gold ( Scutellaria baicalensis ) belonging to the Lamiaceae (Labiatae ). Preferably, golden silver may be dried. Gold is used for edible, industrial, wheat, or ornamental, etc. It is used for cheongyeol-humidity tank, detoxification, antae, gastritis, enteritis, and jinhae. It is used as an anti-inflammatory, congestive, antipyretic, and dry stomach.

Angelica gigas of the present invention refers to the root of the perennial plant Angelica gigas belonging to the umbel (Umbelliferae). Preferably, angelica can be used dry. Angelica is one of the most commonly used herbal medicines. It is used for poor blood circulation, physical weakness, joint pain, headache, abdominal pain, dizziness, constipation, digestive function weakness, internal bleeding caused by bruises, sprains, vascular disease, blood flow stagnation, swelling, and pain. As the main medicinal, it has menstrual control and sedation (鎭靜).

As used in the present invention, the term "extract" refers to an extract obtained by extraction treatment of the ginseng, larvae, broiler, peony, licorice, golden, angelica, or a mixture thereof, and the diluent or concentrate of the extract, and the extract is dried. The resulting dried product, the prepared product or purified product of the extract, or a mixture thereof, and the like, the extract itself and extracts of all formulations that can be formed using the extract are included.

The extract of the present invention may be extracted from natural, hybrid or variant plants of each of the corresponding plants, and may be extracted from plant tissue cultures.

In the extraction of the ginseng, baby chickadee, broiler chicken, peony, licorice, golden, angelica, or a mixture thereof of the present invention, the extraction method is not particularly limited, and can be extracted according to a method commonly used in the art. I can. Non-limiting examples of the extraction method include a hot water extraction method, an ultrasonic extraction method, a filtration method, a reflux extraction method, and the like, and these may be performed alone or in combination of two or more methods.

In the present invention, the type of the extraction solvent used to extract the ginseng, the apex, broiler, peony, licorice, golden, angelica, or a mixture thereof is not particularly limited, and any solvent known in the art may be used. have. Non-limiting examples of the extraction solvent include water; _{C 1} to C ₄ lower alcohols such as methanol, ethanol, propyl alcohol and butyl alcohol; Polyhydric alcohols such as glycerin, butylene glycol and propylene glycol; And hydrocarbon solvents such as methyl acetate, ethyl acetate, acetone, benzene, hexane, diethyl ether, and dichloromethane; Alternatively, a mixture thereof may be used, and preferably, water, lower alcohol, 1,3-butylene glycol, and ethyl acetate may be used alone or in combination of two or more. In the present invention, more preferably, water (or distilled water), 1,3-butylene glycol, or a mixed solvent thereof may be used as a solvent for extracting the herbal medicinal herbs of ginseng, Arabidopsis, broiler, peony, licorice, golden, and angelica. . Using the solvent, a solvent extract can be prepared by extracting the herbal medicinal herbs of ginseng, baby chickadee, broiler, peony, licorice, gold, and angelica at least once, and the solvent extract is distilled under reduced pressure and then freeze-dried or spray-dried. Dry extract can be prepared. In a specific embodiment of the present invention, ginseng extract using an extraction solvent (distilled water: 1,3-butylene glycol = 6:4); Arabidopsis extract; Broiler extract; Peony extract; Licorice extract; Golden extract; Angelicae extract; And two kinds of mixed extracts of ginseng, baby chickadee, broiler, peony, licorice, golden and angelica (Examples 1 to 9).

In the present invention, the extract obtained by heat extraction or cold needle extraction is filtered to remove suspended solid particles, for example, nylon, etc. to filter the particles, or after filtration using a freeze filtration method, etc., or use as such, or freeze-drying, hot air drying, It can be used after drying by spray drying or the like.

As used herein, the term "fraction" means a result obtained by performing fractionation in order to separate a specific component or a specific component group from a mixture containing various various constituents.

The fractionation method for obtaining the fraction in the present invention is not particularly limited, and may be performed according to a method commonly used in the art. Non-limiting examples of the fractionation method include a method of obtaining a fraction from the extract by treating an extract obtained by extracting ginseng, Arabidopsis, broiler, peony, licorice, golden, angelica, or a mixture thereof. have.

In the present invention, the type of solvent used to obtain the fraction is not particularly limited, and any solvent known in the art may be used. Non-limiting examples of the fractionation solvent include polar solvents such as water and alcohol; Nonpolar solvents, such as hexane (Hexane), ethyl acetate (Ethyl acetate), chloroform (Chloroform), and dichloromethane, etc. are mentioned. These may be used alone or in combination of two or more. In the case of using an alcohol in the fractionation solvent, preferably a C ₁ to C ₄ alcohol may be used.

Ginseng extract, Arabidopsis extract, broiler extract, peony extract, licorice extract, golden extract, angelica extract, or a mixture extract thereof have the effect of effectively inhibiting the production of melanin, and specifically reduce the total amount of melanin synthesized. Shows efficacy. In addition, since the composition of the present invention is a material derived from a natural product, it is not toxic, and even when applied to the human body, side effects are not caused, so it can be used as a cosmetic composition.

Melanin is a dark brown pigment produced from melanocytes, which determines the color of human skin and can be expected to brighten the skin by inhibiting melanin pigment.

With respect to the above efficacy, according to a specific embodiment of the present invention, ginseng extract, Arabidopsis extract, broiler extract, peony extract, licorice extract, golden extract, angelica extract or its When the mixed extract was treated by concentration, it was confirmed that the total amount of melanin in melanoma cells was reduced (Example 10).

In particular, the extract or fractions thereof of a mixture containing all of ginseng, Arabidopsis, broiler, peony, licorice, golden and angelica, of the present invention is the synergistic effect or cooperative action between the extracts and/or the active ingredients in the extract. Compared to the single extract of each plant, it can exhibit more excellent skin whitening or complexion improvement efficacy, which is the first to be identified in the present invention.

Specifically, the extract or a fraction thereof of a mixture containing all of ginseng, Arabidopsis, broiler, peony, licorice, golden and angelica, of the present invention, compared to the single extract of ginseng, Arabidopsis, broiler, peony, liquorice, golden or angelica. By further reducing the total amount of melanin in melanoma cells, as a result, more excellent skin whitening or complexion improvement effects may be exhibited.

In the present invention, the mixing ratio of the ginseng, Arabidopsis, broiler, peony, licorice, golden and angelica is preferably 10 to 30: 10 to 30: 10 to 20: 10 to 20: 10 to 20: 10 by weight. To 20: 3 to 15, more preferably 15 to 20: 15 to 20: 15: 15: 12 to 15: 12 to 15: 6 to 10.

According to a specific embodiment of the present invention, the mixed extract and 20: 20: 15 in a mixture ratio of the ginseng, baby chickadee, broiler, peony, licorice, golden, and angelicae is 15: 15: 15: 15: 15: 15: 10 : 15: 12: 12: 6 people mixed extract was prepared and the degree of reduction in the total amount of melanin in melanoma cells was investigated. Or it was found to be even larger than a single extract of Angelicae (Example 10).

The term "whitening" as used in the present invention means any action of inhibiting or preventing the deposition of melanin on the skin by inhibiting the synthesis of melanin.

As used herein, the term "improving complexion" means that skin blemishes such as spots, freckles, and age spots on the face are removed or produced is suppressed, and the skin tone is brightened, so that the overall color of the face is improved aesthetically.

The cosmetic composition of the present invention is a solution, external ointment, cream, foam, nutritional lotion, flexible lotion, pack, softening water, emulsion, makeup base, essence, soap, liquid detergent, bathing agent, sunscreen cream, sun oil, suspension, emulsion It can be prepared in a formulation selected from the group consisting of liquid, paste, gel, lotion, powder, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation, patch, and spray, but is limited thereto. no.

The cosmetic composition of the present invention may additionally include one or more cosmetically acceptable carriers blended in general skin cosmetics, and as common ingredients, for example, oil, water, surfactants, moisturizers, lower alcohols, thickeners , A chelating agent, a colorant, a preservative, a fragrance, and the like may be appropriately blended, but are not limited thereto.

The cosmetically acceptable carrier included in the cosmetic composition of the present invention varies depending on the formulation of the cosmetic composition.

When the formulation of the present invention is an ointment, paste, cream, or gel, as a carrier component, animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc, zinc oxide, etc. May be used, but is not limited thereto. These may be used alone or in combination of two or more.

When the formulation of the present invention is a powder or spray, lactose, talc, silica, aluminum hydroxide, calcium silicate, polyamide powder, etc. may be used as a carrier component. It may include a propellant such as locarbon, propane/butane or dimethyl ether, but is not limited thereto. These may be used alone or in combination of two or more.

When the formulation of the present invention is a solution or emulsion, a solvent, a solubilizing agent or an emulsifying agent may be used as a carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, Propylene glycol, 1,3-butyl glycol oil, and the like may be used, and in particular, cottonseed oil, peanut oil, corn germ oil, olive oil, castor oil and sesame oil, glycerol aliphatic ester, polyethylene glycol or fatty acid ester of sorbitan. May be used, but is not limited thereto. These may be used alone or in combination of two or more.

When the formulation of the present invention is a suspension, as a carrier component, a liquid diluent such as water, ethanol or propylene glycol, an ethoxylated isostearyl alcohol, a suspending agent such as polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, micro Crystalline cellulose, aluminum metahydroxide, bentonite, agar, or tracant may be used, but the present invention is not limited thereto. These may be used alone or in combination of two or more.

When the formulation of the present invention is a soap, an alkali metal salt of a fatty acid, a fatty acid hemiester salt, a fatty acid protein hydrolyzate, isethionate, a lanolin derivative, an aliphatic alcohol, vegetable oil, glycerol, sugar, etc. are used as a carrier component. It may be, but is not limited thereto. These may be used alone or in combination of two or more.

In the cosmetic composition of the present invention, the herbal extract of ginseng, baby chickadee, broiler, peony, licorice, golden, angelica, or a mixture thereof may be included in a dry weight, preferably 0.0001 to 50% by weight of the total weight of the cosmetic composition. , More preferably, it is preferably contained in an amount of 0.0005 to 10% by weight. There is an advantage of showing an excellent whitening or complexion improvement effect within the above range, and there is an advantage of stabilizing the formulation of the composition.

The composition containing the extract or fractions thereof of ginseng, Arabidopsis, broiler, peony, lichen, golden, angelica, or a mixture thereof of the present invention has excellent skin whitening effect. Specifically, the composition of the present invention is excellent in the efficacy of inhibiting the increase in the total amount of melanin.

In addition, since the composition of the present invention is a material derived from a natural product, it is not toxic, and even when applied to the human body, it does not cause side effects, so its utilization as a cosmetic composition is high.

Hereinafter, the configuration and effects of the present invention will be described in more detail through examples. These examples are for illustrative purposes only, and the scope of the present invention is not limited by these examples.

Example 1: Preparation of ginseng extract

After the ginseng was dried and minced, 100 g of dry weight was put into a flask, and extracted by cold soaking for 3 days with 1000 g of an extraction solvent (distilled water: 1,3-butylene glycol = 6:4). The cold-precipitated extract was filtered through a filter having a pore size of 0.2 μm to prepare a ginseng extract.

Example 2: Preparation of Arabidopsis extract

After drying and mincing the ears of the baby parts, 100 g of dry weight was put into a flask, and extracted by cold soaking for 3 days with 1000 g of an extraction solvent (distilled water: 1,3-butylene glycol = 6:4). The cold-precipitated extract was filtered through a filter having a pore size of 0.2 µm to prepare a Arabidopsis extract.

Example 3: Preparation of broiler extract

After the broilers were dried and minced, 100 g of dry weight was put into a flask and extracted by cold soaking for 3 days with 1000 g of an extraction solvent (distilled water: 1,3-butylene glycol = 6:4). The chilled extract was filtered through a filter having a pore size of 0.2 μm to prepare a broiler extract.

Example 4: Preparation of peony extract

After drying and mincing the peony, 100 g of dry weight was put into a flask, and extracted by cold soaking with 1000 g of an extraction solvent (distilled water: 1,3-butylene glycol = 6:4) for 3 days. The chilled extract was filtered through a filter having a pore size of 0.2 μm to prepare a peony extract.

Example 5: Of licorice extract Produce

After drying and slicing the licorice, 100 g of dry weight was put into a flask and extracted by cold soaking for 3 days with 1000 g of an extraction solvent (distilled water: 1,3-butylene glycol = 6:4). The cold-precipitated extract was filtered through a filter having a pore size of 0.2 μm to prepare a licorice extract.

Example 6: Preparation of golden extract

After the gold was dried and minced, 100 g of dry weight was put into a flask, and extracted by cold soaking for 3 days with 1000 g of an extraction solvent (distilled water: 1,3-butylene glycol = 6:4). The cold-precipitated extract was filtered through a filter having a pore size of 0.2 μm to prepare a golden extract.

Example 7: Preparation of Angelicae extract

After drying and slicing angelica, 100 g of dry weight was put into a flask, and extracted by cold soaking with 1000 g of an extraction solvent (distilled water: 1,3-butylene glycol = 6:4) for 3 days. The cold-precipitated extract was filtered through a filter having a pore size of 0.2 μm to prepare Angelicae extract.

Example 8: Preparation of mixed extracts of ginseng, baby chickadee, broiler chicken, peony, licorice, golden and angelica

After drying and mincing ginseng, ear of the baby chickadee, broiler, peony, cornflower, golden and angelica, 100g of dry weight (ginseng 15g, ear of baby chickadee 15g, broiler 15g, peony 15g, cornflower 15g, gold 15g, angelica 10g) It was placed in a flask and extracted by cold soaking for 3 days with 1000 g of an extraction solvent (distilled water: 1,3-butylene glycol = 6:4). The cold-precipitated extract was filtered through a filter having a pore size of 0.2 µm to prepare a mixture extract of ginseng, Arabidopsis, broiler, peony, licorice, golden and angelicae.

Example 9: Preparation of mixed extracts of ginseng, baby chickadee, broiler chicken, peony, licorice, golden and angelica

After drying and mincing ginseng, ears of baby chickadee, broiler chickens, peony, cornflower, golden and angelica, 100g of dry weight (20g ginseng, ear of baby chickweed 20g, broiler 15g, peony 15g, cornflower 12g, gold 12g, angelica 6g) It was placed in a flask and extracted by cold soaking for 3 days with 1000 g of an extraction solvent (distilled water: 1,3-butylene glycol = 6:4). The cold-precipitated extract was filtered through a filter having a pore size of 0.2 µm to prepare a mixture extract of ginseng, Arabidopsis, broiler, peony, licorice, golden and angelicae.

Example 10: Whitening effect-Investigation of the effect of reducing total melanin

The extracts of Examples 1 to 9 were added to the culture medium of mouse melanoma cells (B-16 mouse melanoma cells) to test the whitening effect at the cellular level. For comparison, no separate treatment was applied to the negative control group, and arbutin was added to the positive control group.

Specifically, the final concentration (% by weight) of the herbal medicine extracts of Examples 1 to 9 was tested to be 0.1% or 1%, and arbutin, a positive control, was added to the medium so as to be 200 μg/ml, respectively, and B-16 The melanoma cells were treated and cultured for 3 days.

Thereafter, the cells were treated with trypsin, removed from the culture vessel, centrifuged, and melanin was extracted. The detached cells were boiled for 10 minutes by adding 1 ml of sodium hydroxide solution (1N concentration) to dissolve melanin, and the absorbance was measured at 400 nanometers (nm) using a spectrophotometer to measure the amount of melanin produced.

The amount of melanin was measured by a method of expressing the absorbance per unit cell count (10 ⁶ cells), and was calculated as an inhibition rate (%) for the total amount of melanin relative to the negative control, and the results are shown in Table 1 below. Also, the experiment was repeated 3 times.

sample Total melanin (Absorbance) Inhibition rate (%) Negative control 0.082 - Arbutin (200㎍/ml) 0.042 48.78 Example 1 (0.1%) 0,069 15.85 Example 1 (1.0%) 0.054 34.15 Example 2 (0.1%) 0.070 14.63 Example 2 (1.0%) 0.058 29.27 Example 3 (0.1%) 0.072 12.20 Example 3 (1.0%) 0.060 26.83 Example 4 (0.1%) 0.075 8.54 Example 4 (1.0%) 0.065 20.73 Example 5 (0.1%) 0.074 9.76 Example 5 (1.0%) 0.062 24.39 Example 6 (0.1%) 0.076 7.32 Example 6 (1.0%) 0.068 17.07 Example 7 (0.1%) 0.080 2.44 Example 7 (1.0%) 0.073 10.98 Example 8 (1.0%) 0.049 40.24 Example 9 (1.0%) 0.043 47.56

As can be seen from the results of Table 1, ginseng extract, Arabidopsis extract, broiler extract, peony extract, licorice extract, golden extract, angelica extract and mixed extracts of these herbal medicines inhibit melanin synthesis and reduce the total amount of melanin. In addition, it was found that when extracting by mixing 7 herbal medicines, it has the effect of significantly reducing the total amount of melanin compared to each herbal extract alone. In particular, in the case of Example 9, which was extracted by mixing 7 kinds of herbal medicines by weight of 20:20:15:15:15:12:12:6, it can be confirmed that it exhibits excellent melanin total reduction efficacy similar to the conventionally known whitening substance arbutin. there was.

Manufacturing example 1: Preparation of essence containing the mixed extract of the present invention

A cosmetic composition of an essence formulation was prepared as shown in Table 2 below (unit: wt%).

Raw material name Content (% by weight) Cetearyl alcohol
Cetearyl glucoside
Jojoba seed oil
Silica
glycerin
Example 9 extract
Purified water 2
One
5
0.5
10
5
To 100

Manufacturing example 2: Preparation of a cream containing the mixed extract of the present invention

As shown in Table 3 below, a cream-formed cosmetic composition was prepared (unit:% by weight).

Composition Content (% by weight) Example 9 extract
Stearic acid
ethanol
Potassium hydroxide
glycerin
Propylene glycol
antiseptic
incense
Purified water 5
15.0
1.0
0.7
5.0
3.0
Appropriate amount
Appropriate amount
to 100

Claims (7)

delete A cosmetic composition for whitening or improving complexion, characterized in that it comprises a mixed extract of ginseng, baby chickadee, broiler, peony, licorice, golden and angelica, or a fraction thereof as an active ingredient.
The method of claim 2, wherein the mixing ratio of the ginseng, Arabidopsis, broiler, peony, licorice, golden, and angelica is 10 to 30: 10 to 30: 10 to 20: 10 to 20: 10 to 20: 10 to 20: Cosmetic composition for whitening or improving complexion, characterized in that 3 to 15.
The method of claim 2, wherein the mixing ratio of the ginseng, Arabidopsis, broiler, peony, licorice, golden, and angelica is 15 to 20: 15 to 20: 15: 15: 12 to 15: 12 to 15: 6 to A cosmetic composition for whitening or improving complexion, characterized in that it is 10.
The method of claim 2, wherein the extract is obtained by extraction with at least one solvent selected from the group consisting _{of water, C 1} to C _{4 lower alcohol, 1,3-butylene glycol, and ethyl acetate.} Cosmetic composition for whitening or improving complexion.
The cosmetic composition of claim 5, wherein the solvent is a mixture of water and 1,3-butylene glycol in a weight ratio of 6:4.
The cosmetic composition of claim 2, wherein the whitening or complexion improvement is due to a decrease in the total amount of melanin in melanoma cells.