KR102039456B1 - Method for manufacturing composition for depilation - Google Patents

Abstract

The present invention relates to a method for preparing a hair removal composition, and more particularly, using a natural material, such as sugar, while having an excellent hair removal effect, is safe for the human body, and reduces skin irritation and redness that may occur during hair removal. It relates to a method for preparing the hair removal composition that can be effectively reduced.

Description

Method for manufacturing hair removal composition {Method for manufacturing composition for depilation}

The present invention relates to a method for preparing a hair removal composition, and more particularly, using a natural material, such as sugar, while having an excellent hair removal effect, is safe for the human body, and reduces skin irritation and redness that may occur during hair removal. It relates to a method for preparing the hair removal composition that can be effectively reduced.

Depilation is the act of removing hair other than hair, which has been performed continuously for a long time. Representative hair removal methods include a method of melting and removing hair using a hair removal agent as described in the following patent document, a method of applying a hair removal cream to the skin, applying a strip and then removing the strip to remove the hair.

<Patent Documents>

1. Korean Patent Application Publication No. 10-2008-0001056 (published Jan. 03, 2008) "Depilatory composition comprising a thioglycolic acid or a derivative thereof and a method for producing the same"

2. Korean Patent Publication No. 10-2012-0041042 (published on April 30, 2012) "Epilation composition"

However, the hair removal agent and the hair removal cream used in the conventional hair removal method have a problem that the safety is not ensured because they are manufactured with chemicals.

The present invention is to solve the above problems of the prior art,

An object of the present invention is to provide a method for preparing a composition for hair removal which is safe to the human body while having excellent hair removal effect using a natural material such as sugar.

Another object of the present invention is to provide a method for preparing a composition for hair removal which can effectively reduce skin irritation and redness that may occur during hair removal.

The present invention is implemented by the embodiment having the following configuration in order to achieve the above object.

According to one embodiment of the present invention, the method for preparing a hair removal composition according to the present invention comprises the first heating step of heating at a constant temperature for a predetermined time by gradually increasing the temperature in a state of mixing and stirring water, sugar and fruit acid solution; A second heating step of adding a saccharide to the mixture heated in the first heating step and heating the mixture for a predetermined time at a predetermined temperature, and a cooling step of cooling the mixture heated in the second heating step to a predetermined temperature; Characterized in that it comprises a.

According to another embodiment of the present invention, the first heating step in the method for producing a composition for hair removal according to the present invention is 10 to 40 parts by weight of water, 50 to 75 parts by weight of sugar and 10 to 30 parts by weight of fruit acid solution And gradually increasing the temperature in a stirred state at 25 to 35rpm to reach 100 to 120 ℃ and then maintained for 60 to 120 minutes, the second heating step is 5 to 15 to the mixture heated in the first heating step It is carried out by further mixing the parts by weight of saccharide and stirred at 25 to 35rpm for 100 to 200 minutes at 100 to 120 ℃, the cooling step is heated to 70 to 80 ℃ the mixture heated in the second heating step After cooling slowly, the functional additive is mixed and then cooled.

According to another embodiment of the present invention, the functional additive in the method of manufacturing the composition for hair removal according to the present invention for preventing damage to the skin in the process of peeling off after removing the composition for application to the skin It comprises a first additive, the first additive is characterized in that it comprises a snail mucus filtrate, cheonma extract, bovine cactus stem extract, lotus root extract and aloe vera leaf extract.

According to another embodiment of the present invention, in the method for preparing the composition for hair removal according to the present invention, the functional additive further comprises a second additive for reducing body odor from the skin and a third additive for improving skin wrinkles. It includes, the second additive is formed by mixing the weight of the cedar extract and the gardenia extract in a weight ratio of 1: 1, the third additive is a ginyanam extract, fresh water extract and oak extract of 1: 1: 1 Characterized in that the mixture is formed in a weight ratio.

The present invention can obtain the following effects by the above embodiment.

The present invention is safe to the human body by using sugar, which is a natural material, and has an excellent hair removal effect.

In addition, the present invention has the effect of reducing the skin irritation and redness (redness) that may occur during hair removal.

Hereinafter will be described in detail a manufacturing method of the composition for hair removal according to the present invention. Unless otherwise defined, all terms in this specification are equivalent to the general meaning of the terms understood by those of ordinary skill in the art to which the present invention pertains and, if they conflict with the meanings of the terms used herein, Follow the definition used in the specification. In addition, detailed description of well-known functions and configurations that may unnecessarily obscure the subject matter of the present invention will be omitted. Throughout the specification, when a part is said to "include" a certain component, it means that it may further include other components, without excluding other components unless specifically stated otherwise.

Hair removal composition according to an embodiment of the present invention is a first heating step for heating for a predetermined time at a predetermined temperature by gradually increasing the temperature in a state of mixing and stirring water, sugar and fruit acid solution, and heating in the first heating step And a second heating step of adding a sugar to the mixture and stirring the mixture for a predetermined time at a predetermined temperature, and a cooling step of cooling the mixture heated in the second heating step to a predetermined temperature.

The first heating step is a step of gradually increasing the temperature in a state of mixing and stirring water, sugar and fruit acid solution and heating at a predetermined temperature for a predetermined time, for example, the first heating step is 10 to 40 parts by weight of water, sugar 50 To 75 parts by weight and 10 to 30 parts by weight of the fruit acid solution are mixed and stirred at 25 to 35rpm to gradually increase the temperature to reach 100 to 120 ℃ and then carried out by maintaining for 60 to 120 minutes. The sugar may be used, for example, sugar, the fruit acid solution refers to a solution containing an acid obtained from a variety of fruits, for example, may be composed of 20% by weight of lemon juice and 80% by weight of water.

The second heating step is a step of adding a saccharide to the mixture heated in the first heating step and heating for a predetermined time at a predetermined temperature while stirring, for example, the second heating step is heated in the first heating step The mixture is further mixed with 5 to 15 parts by weight of sugar and held at 100 to 120 ° C. for 100 to 200 minutes while stirring at 25 to 35 rpm.

The cooling step is a step of cooling the mixture heated in the second heating step to a predetermined temperature, in the cooling step it is possible to cool by mixing a functional additive in the mixture, for example, the mixture heated in the second heating step After slowly cooling to 70 to 80 ℃ After mixing the functional additives it is carried out by cooling to 30 to 40 ℃. The functional additive is a herbal essential oil, a pH adjusting agent, a first additive for preventing damage to the skin in the process of peeling off after removing the composition for hair removal on the skin, a second additive for reducing body odor from the skin It may include a third additive for improving skin wrinkles. The hair removal composition obtained through the cooling step can be stored at room temperature, and in use, the composition is applied to the skin to remove hair after reaching a temperature of 30 to 40 ° C. using a microwave oven or the like. After attaching a strip of cloth after the predetermined time after the composition is hardened to remove the hair by pulling the strip.

It is preferable that the herbal essential oil is mixed in an amount of 0.02 to 0.2 parts by weight. Herbal essential oils extracted from various herbs may be used, and products directly extracted from herbs or commercially available products may be used.

The pH adjusting agent is a configuration used to adjust the final pH of the hair removal composition, wherein the hair removal composition is added to have a pH of 5 to 7.

The first additive is an additive for preventing damage to the skin in the process of removing the composition for applying hair to the skin and then hardening, preferably 0.5 to 1.5 parts by weight, snail mucus filtrate, cheonma extract It includes any one or more selected from the group consisting of botanical cactus stem extract, lotus root extract, aloe vera leaf extract. The first additive is preferably made by mixing the snail mucus filtrate, cheonma extract, bollard cactus stem extract, lotus root extract and aloe vera leaf extract in a weight ratio of 0.7: 1: 1: 1: 0.7. The snail mucus filtrate can be obtained from a snail using a conventional method. For example, after washing the snail in running water, the snail is placed in a container to obtain a liquid mucus, and the mucus is filtered using a filter and concentrated under reduced pressure. And then lyophilized. The cheonma extract, botanical cactus stem extract, lotus root extract, aloe vera leaf extract is mixed with cheonma, botanical cactus stem, lotus root, aloe vera leaf in ethanol after a certain time to remove the dry powder and concentrated under reduced pressure And freeze-dried. The hair removal composition of the present invention is put in a microwave oven immediately before use, applied to the skin and then applied to the skin and then attached to a strip made of cloth, and when the composition is hard on the skin, the strip is pulled to remove the hair. The irritation may occur, for example, the skin may become sore or red. The composition may further include a first additive to effectively prevent damage to the skin in the process of applying the hair removal composition to the skin and then hardening it off. Can be.

The second additive is an additive for reducing body odor from the skin, preferably 0.5 to 1.5 parts by weight, and includes any one or more selected from the group consisting of cedar extract and gardenia extract. It is preferable that the second additive is made of the cedar extract and the gardenia extract are mixed in a weight ratio of 1: 1. The cedar extract and the gardenia extract are obtained by mixing each of the cedar and the gardenia leaves with ethanol, after a certain period of time to remove the dry matter and concentrated under reduced pressure and freeze-dried. The hair removal composition may be used to remove the hairs of the armpits. In the case of the armpits, there is a odor known as cancer, and the composition further includes a second participant, and at the same time, hair loss and concomitant reduction of body odors is also aimed at. Can be.

The third additive is an additive for improving skin wrinkles, preferably 0.5 to 1.5 parts by weight, and includes any one or more selected from the group consisting of ginseng extract, fresh water extract and oak extract. The second additive is preferably used by mixing the Ginia nam extract, fresh water extract and oak extract in a weight ratio of 1: 1: 1. The Gingia nam extract, fresh water extract and true tree extract is obtained by mixing each of the ginia nam leaf, gingi biloba leaf, and true oak leaf in ethanol, after a certain period of time to remove the dry matter and concentrated under reduced pressure and freeze-dried . Since the hair removal composition is applied to the skin and used, the third additive may further include the third additive, and at the same time, the hair removal effect may be additionally improved.

Hereinafter, the present invention will be described in more detail with reference to Examples. However, these are only intended to describe the present invention in more detail, but the scope of the present invention is not limited thereto.

Example 1 Preparation of Functional Additive Sample

(1) After washing the snail in running water, put the snail into a container to obtain liquid mucus. The mucus was filtered through a filter, concentrated under reduced pressure, and lyophilized to obtain snail mucus filtrate (sample 1-1). Got it. 100 g of each dried and pulverized chunky horse, bovine cactus stem, lotus root, and aloe vera leaf were immersed in 300 ml of ethanol for 48 hours, and the extract was removed under reduced pressure, concentrated under reduced pressure, and freeze-dried. Cactus stem extract (sample 1-3), lotus root extract (sample 1-4), and aloe vera leaf extract (sample 1-5) were obtained. Samples 1-1 were obtained by mixing samples 1-1 and 1-2 in a weight ratio of 1: 1, samples 1-7 were obtained by mixing samples 1-4 and 1-5 in a weight ratio of 1: 1, and sample 1 Samples 1-8 were obtained by mixing -1, 1-2, 1-3, 1-4 and 1-5 in a weight ratio of 0.7: 1: 1: 1: 0.7.

(2) 100 g of dried and pulverized cedar leaves and gardenia leaves were immersed in 300 ml of ethanol for 48 hours, and the extract was removed under reduced pressure and freeze-dried to extract the cedar extract (Sample 2-1) and gardenia. An extract (sample 2-2) was obtained. Samples 2-1 and 2-2 were mixed at a weight ratio of 1: 1 to obtain sample 2-3.

(3) 100 g of each dried and pulverized Ginia nambu leaf, fresh green leaf, and oak tree leaf were immersed in 300ml of ethanol for 48 hours, and the extract was removed under reduced pressure and freeze-dried. ), Fresh water extract (sample 3-2) and oak extract (sample 3-3). Sample 3-1 was mixed with sample 3-2 in a weight ratio of 1: 1 to obtain sample 3-4. Sample 3-5 was obtained by mixing samples 3-2 and 3-3 in a weight ratio of 1: 1. Samples 3-6 were obtained by mixing 3-1, 3-2 and sample 3-3 in a weight ratio of 1: 1: 1.

Example 2 Preparation of Sample for Hair Removal Composition

(1) 25 parts by weight of purified water, 60 parts by weight of sugar and 20 parts by weight of fruit acid solution were mixed and gradually heated to a temperature of 110 ° C. while stirring at 30 rpm, and then maintained for 90 minutes to perform a first heating step. The fruit acid solution consists of 20% by weight lemon juice and 80% by weight purified water.

(2) 20 parts by weight of sugar was further mixed with the mixture heated in the first heating step, and the second heating step was performed by maintaining at 150C for 150 minutes while stirring at 30 rpm.

(3) The mixture heated in the second heating step was gradually cooled to 75 ° C., and then the functional additives were mixed in the ratio of Table 1 below, and then cooled to 35 ° C. to obtain a composition.

Content of added functional additives (parts by weight) Samples 1-1 to 1-8 Samples 2-1 to 2-3 Samples 3-1 to 3-6 Composition 1 1 (sample 1-1) 0 0 Composition 2 1 (sample 1-2) 0 0 Composition 3 1 (sample 1-3) 0 0 Composition 4 1 (sample 1-4) 0 0 Composition 5 1 (sample 1-5) 0 0 Composition 6 1 (sample 1-6) 0 0 Composition 7 1 (sample 1-7) 0 0 Composition 8 1 (sample 1-8) 0 0 Composition 9 0 1 (sample 2-1) 0 Composition 10 0 1 (sample 2-2) 0 Composition 11 0 1 (sample 2-3) 0 Composition 12 0 0 1 (sample 3-6) Composition 13 1 (sample 1-8) 1 (sample 2-3) 0 Composition 14 1 (sample 1-8) 0 1 (sample 3-6) Composition 15 1 (sample 1-8) 1 (sample 2-3) 1 (sample 3-6) Composition 16 0 1 (sample 2-3) 1 (sample 3-6) Composition 17 0 0 0

Example 3 Cytotoxicity Evaluation of Functional Additives

MTT assays were performed on Samples 1-1 to 1-8, Samples 2-1 to 2-3, and Samples 3-1 to 3-6. The cultured RAW 264.7 cells were incubated with LPS (1 μg / mL) and Samples 1-1 to 1-8, Samples 2-1 to 2-3, and Samples 3-1 to 3-6 for 36 hours. . After incubation, MTT solution was added 10μL each and incubated for 12 hours. After removing the supernatant, DMSO was added, the plate was shaken well using a plate mixer, and the absorbance was measured at 540 nm. Cytotoxicity was assessed compared to the control treated with the stimulant. As a result, it was confirmed that each of Samples 1-1 to 1-8, Samples 2-1 to 2-3, and Samples 3-1 to 3-6 did not show cytotoxicity at concentrations of 100 ug / mL or less.

Example 4 Evaluation of Hair Removal Effect and Skin Damage Prevention Effect

(1) hair removal effect evaluation

Hair removal effect was confirmed in 17 males in their 20s and 30s with hair on their legs. After heating the compositions 1 to 17 with a microwave oven, apply each of the compositions 1 to 17 to the hairy leg area, attach a strip of cloth, and after 5 minutes, confirm that the composition is completely hardened, and then remove the strip to remove hairs. It was confirmed visually. As a result of visual confirmation, when the compositions 1 to 17 were used, it was confirmed that all hairs were removed. Therefore, it can be seen that the composition for hair removal having a hair removal effect can be prepared using natural materials such as sugar, and it is confirmed that even if a certain amount of functional additives 1 to 3 are added to the composition for hair removal, there is no effect on the hair removal effect. Can be.

(2) evaluation of skin damage prevention effect

1) The effect of preventing skin damage when using the composition for hair removal was examined in 24 men in their 20s and 30s without skin disease to skin allergy symptoms. The compositions 1 to 8, 11, 12, 15 and 17 were heated with a microwave oven and each composition was applied to the hairy leg area and then the strip of cloth was removed. The same procedure was performed three times at two-day intervals. After performing the final three times, and confirmed whether the skin abnormalities such as erythema and the like can be confirmed with the subjective feeling of skin bleeding, such as shown in Table 2. In addition, the legs were exposed to the sun for 10 minutes after the last 3 trials, and the test site before and after the exposure was observed to observe the presence of erythema and edema (only for 18 subjects to which the compositions 1 to 8 and 15 were applied). . Skin response rate (mean response rate) is calculated in the following manner and shown in Table 3. Skin responsiveness = score × number of responses × 100 × 1/2) / [3 (maximum score) × total number of subjects (n)] (Score of skin reaction is 0 (no response), 0.5 (faint or mild erythema) , 1 (clear but weak erythema), 2 (obvious erythema, papules and vesicles), 3 (severe erythema and alveolar vesicles))

2) In Table 2, when using the compositions 11, 12, and 17, subjective skin abnormalities and visually identifiable skin abnormalities occur, and when the compositions 1 to 8 and 15 are used, the above abnormalities do not occur. It can be seen that, when the functional additive 1 is added to the hair removal composition, it can be seen that damage to the skin can be prevented from occurring during the peeling process after the skin is hardened. In addition, when the hair is physically removed using the hair removal composition, the skin may be weakened to some extent in any case, and the skin may be easily damaged against an external stimulus (experiment using ultraviolet rays as the stimulator in the present invention). In Table 3, it can be seen that the compositions 8 and 15 cause less damage to the skin than the compositions 1 to 7, snail mucus filtrate, cheonma extract, bovine cactus stem extract, lotus root extract, aloe vera leaf It can be seen that when the mixture is used in a proportion rather than using the respective extracts, the effect of preventing skin damage can be improved.

Composition One 2 3 4 5 6 7 8 11 12 15 17 Subjective
Skin problems × × × × × × × × ○ ○ × ○ Visual check skin abnormalities × × × × × × × × ○ ○ × ○

Composition One 2 3 4 5 6 7 8 15 Responsiveness (%)
4.7 4.4 5.0 4.8 4.9 5.1 4.7 3.2 3.4

Example 5 Confirmation of Body Deodorization Effect

(1) The effect of reducing body odor was confirmed when the hair removal composition was used in 14 males who were aware of severe odor (arm cancer) in the armpit. The compositions 8-12, 15, and 17 were heated in a microwave oven and each composition was applied to one hairy underarm area (the composition was not used for the other underarm area) and the cloth strips were removed. Aside from the panel for evaluating odors, the panel compares the subject's both armpit odors and subjectively evaluates the effect of body odor reduction, and the results are shown in Table 4, and the results of the removal using the 5-point scale method are relatively removed. If it was good, it evaluated as 5 points and bad. In addition, after measuring the smell of both armpits using an odor meter (XP-329 Ⅲ / New cosmos Ele. / Japan) after the above experiment (only performed for 6 subjects applied to the composition 9 to 11), odor reduction rate (Smell reduction percentage (%) = (composition axillary odor value-composition axillary odor value) / composition axillary odor value) x 100) was calculated and shown in Table 5.

(2) Looking at Table 4, it can be confirmed that the score is relatively low when using the composition 8, 12, 17, the relatively high score when using the composition 9 to 11 and 15, the functional additive 2 to the hair removal composition If you add it, you can see that it can also remove body odor while removing hair. In addition, looking at Table 5, it can be seen that the composition 11 has a greater reduction in odor compared to the compositions 9 and 10, the effect of reducing the body odor when mixed with a certain ratio than the use of the cedar extract and gardenia extract, respectively It can be seen that can be improved.

Composition 8 9 10 11 12 15 17 smell 2.5 4.1 3.9 4.3 2.7 4.2 1.8

Composition 9 10 11 Odor Reduction Rate (%) 60 63 88

<Example 6> Wrinkle improvement effect confirmed

(1) cell proliferation effect

The cultured HDFn was inoculated in a 96 well plate to be 1.0x10 ¹⁵ cells / ml, and then replaced with DMEM medium containing no FBS, samples 3-1 to 3-6 were added, and cultured for 24 hours (sample 3). -1 to 3-6 each to a final concentration of 100 ug / mL). After incubation, 10 μl of a solution of MTT (3- (4,5-dimethyl-thiazol-2-yl) 2,5-diphenyl tetrazolium: 5 mg / ml) was added thereto, and the reaction solution was removed after 6 hours of reaction. 100 μl of DMSO was added to each well to dissolve the stained cells, and the absorbance at 570 nm was measured. Cell proliferation was calculated and shown in Table 6 (Cell proliferation (%) = (OD of sample-OD of control) / OD of control × 100), it was found that all samples 3-1 to 3-6 improve the cell proliferation It can be seen that when using the sample 3-6 formed by mixing the samples 3-1, 3-2 and 3-3 in a weight ratio of 1: 1: 1, it can be seen that it can further increase the wrinkle improvement effect.

Untreated Sample 3-1 Sample 3-2 Sample 3-3 Sample 3-4 Sample 3-5 Sample 3-6 Cell proliferation (%) 0 33 32 34 32 35 42

(2) collagen synthesis ability

Incubate the cultured HDFn in 96 well plates to 1x10 ¹⁵ cells / ml, replace with DMEM / F12 (3: 1) medium without FBS, and then add samples 3-1 to 3-6 Incubated for hours (final concentration 100 μg / mL for each of Samples 3-1 to 3-6). Thereafter, the culture medium supernatant was collected and the amount of procollagen was measured using a Procollagen type 1 C-peptide (PIP) EIA kit, and the results are shown in Table 7. Looking at Table 7, it can be seen that Sample 3-6 has a greater amount of collagen 1 than Samples 3-1 to 3-5. Through this, it can be seen that the effect of improving wrinkles when using a mixture at a certain ratio than when using the ginguina extract, palmidae extract and oak extract, respectively. Therefore, it can be seen that the functional additive 3 has a wrinkle improvement effect, and when the functional additive 3 is used in the hair removal composition, it is possible to provide a wrinkle improvement effect as well as a hair removal effect.

Untreated Sample 3-1 Sample 3-2 Sample 3-3 Sample 3-4 Sample 3-5 Sample 3-6 collagen 1
content(%) 100 135 133 134 129 132 149

In the above, the Applicant has described preferred embodiments of the present invention, but these embodiments are merely one embodiment for implementing the technical idea of the present invention, and any changes or modifications may be made as long as the technical idea of the present invention is implemented. Should be interpreted as being within the scope.

Claims (4)

A first heating step of heating in a state of mixing and stirring water, sugar and fruit acid solution, a second heating step of adding and heating a sugar to the mixture heated in the first heating step, and heating in the second heating step A cooling step of cooling the prepared mixture,
The sugar is used sugar, the fruit acid solution is made of lemon juice and water,
In the cooling step, the functional additive is mixed,
The functional additive is a first additive to prevent damage to the skin in the process of removing the composition after applying the hair removal composition to the skin, and a second additive to reduce the body odor from the skin, and to promote collagen synthesis A third additive to improve skin wrinkles,
The first additive includes cheonma extract, bovine cactus stem extract, lotus root extract and aloe vera leaf extract,
The second additive includes a cedar extract and gardenia extract,
The third additive is a manufacturing method of the hair removal composition, characterized in that the Ginia nam extract, fresh water extract and oak extract is formed by mixing in a weight ratio of 1: 1: 1. The method of claim 1,
In the first heating step, 10 to 40 parts by weight of water, 50 to 75 parts by weight of sugar and 10 to 30 parts by weight of fruit acid solution are mixed and gradually raised to a temperature of 100 to 120 ° C. under stirring at 25 to 35 rpm. Is carried out for 60 to 120 minutes
The second heating step is carried out by further mixing 5 to 15 parts by weight of the sugar in the mixture heated in the first heating step and maintained at 100 to 120 ℃ for 100 to 200 minutes while stirring at 25 to 35 rpm,
The cooling step is a method for producing a composition for hair removal, characterized in that the cooling is carried out after slowly cooling the mixture heated in the second heating step up to 70 to 80 ℃ mixed functional additives. The method of claim 2,
The first additive is a method for producing a composition for hair removal characterized in that it further comprises a snail mucus filtrate. The method of claim 3,
The second additive is a method for producing a hair removal composition, characterized in that the epithelium extract and Gardenia extract are mixed in a weight ratio of 1: 1.