KR102014890B1 - 췌장암의 존재를 결정하기 위한 방법, 어레이 및 그의 용도 - Google Patents

췌장암의 존재를 결정하기 위한 방법, 어레이 및 그의 용도 Download PDF

Info

Publication number
KR102014890B1
KR102014890B1 KR1020137026248A KR20137026248A KR102014890B1 KR 102014890 B1 KR102014890 B1 KR 102014890B1 KR 1020137026248 A KR1020137026248 A KR 1020137026248A KR 20137026248 A KR20137026248 A KR 20137026248A KR 102014890 B1 KR102014890 B1 KR 102014890B1
Authority
KR
South Korea
Prior art keywords
delete delete
expression
measuring
antibody
biomarkers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020137026248A
Other languages
English (en)
Korean (ko)
Other versions
KR20140040118A (ko
Inventor
칼 아르네 크리스테르 보레바에크
라르스 베르틸 크리스테르 빈그렌
Original Assignee
이뮤노비아 에이비
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 이뮤노비아 에이비 filed Critical 이뮤노비아 에이비
Publication of KR20140040118A publication Critical patent/KR20140040118A/ko
Application granted granted Critical
Publication of KR102014890B1 publication Critical patent/KR102014890B1/ko
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57525Immunoassay; Biospecific binding assay; Materials therefor for cancer of the liver or pancreas
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/54Interleukins [IL]
    • G01N2333/5406IL-4
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/54Interleukins [IL]
    • G01N2333/5412IL-6
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/54Interleukins [IL]
    • G01N2333/5437IL-13

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Gastroenterology & Hepatology (AREA)
KR1020137026248A 2011-03-04 2012-03-05 췌장암의 존재를 결정하기 위한 방법, 어레이 및 그의 용도 Expired - Fee Related KR102014890B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1103726.4A GB201103726D0 (en) 2011-03-04 2011-03-04 Method, array and use thereof
GB1103726.4 2011-03-04
PCT/GB2012/050483 WO2012120288A2 (en) 2011-03-04 2012-03-05 Method, array and use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020197024469A Division KR20190101489A (ko) 2011-03-04 2012-03-05 췌장암의 존재를 결정하기 위한 방법, 어레이 및 그의 용도

Publications (2)

Publication Number Publication Date
KR20140040118A KR20140040118A (ko) 2014-04-02
KR102014890B1 true KR102014890B1 (ko) 2019-08-27

Family

ID=43923218

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020197024469A Ceased KR20190101489A (ko) 2011-03-04 2012-03-05 췌장암의 존재를 결정하기 위한 방법, 어레이 및 그의 용도
KR1020137026248A Expired - Fee Related KR102014890B1 (ko) 2011-03-04 2012-03-05 췌장암의 존재를 결정하기 위한 방법, 어레이 및 그의 용도

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1020197024469A Ceased KR20190101489A (ko) 2011-03-04 2012-03-05 췌장암의 존재를 결정하기 위한 방법, 어레이 및 그의 용도

Country Status (9)

Country Link
US (4) US9863960B2 (https=)
EP (1) EP2681563A2 (https=)
JP (1) JP6161542B2 (https=)
KR (2) KR20190101489A (https=)
CN (2) CN107064518A (https=)
CA (1) CA2828338A1 (https=)
GB (1) GB201103726D0 (https=)
MX (1) MX363201B (https=)
WO (1) WO2012120288A2 (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008117067A2 (en) 2007-03-27 2008-10-02 Carl Arne Krister Borrebaeck Protein signature/markers for the detection of adenocarcinoma
GB201103726D0 (en) 2011-03-04 2011-04-20 Immunovia Ab Method, array and use thereof
GB201319878D0 (en) * 2013-11-11 2013-12-25 Immunovia Ab Method, Array and use thereof
KR101658164B1 (ko) * 2014-04-28 2016-09-21 서강대학교산학협력단 브롬 동위원소 신호를 이용한 자유 라디칼-개시 펩타이드 시퀀싱 질량분석
KR20150129932A (ko) * 2014-05-12 2015-11-23 연세대학교 산학협력단 보체인자 b 단백질에 특이적으로 결합하는 항체를 포함하는 췌장암 진단용 키트
CN105572276B (zh) * 2014-11-07 2018-12-18 上海市第六人民医院 胰腺癌诊断标记物组合、应用及其测定方法
CN104698170A (zh) * 2015-03-17 2015-06-10 任传利 Il-11作为生物标记物在胰腺癌诊断和预后评价的方法
EP3073268A1 (en) * 2015-03-27 2016-09-28 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts Biomarker panel for diagnosing cancer
JP5852759B1 (ja) * 2015-04-01 2016-02-03 株式会社キュービクス 遺伝子発現解析による膵臓癌の検出
GB201516801D0 (en) 2015-09-22 2015-11-04 Immunovia Ab Method, array and use thereof
JP6392201B2 (ja) * 2015-12-04 2018-09-19 株式会社キュービクス 遺伝子発現解析による膵臓癌の検出
JP5970123B1 (ja) * 2015-12-04 2016-08-17 株式会社キュービクス 遺伝子発現解析による膵臓癌の検出
CA3013522A1 (en) * 2016-02-05 2017-08-10 Dana Genetic A/S Method for diagnosing and treating cancer using antibodies that bind to c1 inactivator, c reactive protein and/or complement component c4
GB201608192D0 (en) 2016-05-10 2016-06-22 Immunovia Ab Method, array and use thereof
CN116908452A (zh) 2016-12-16 2023-10-20 布里格姆及妇女医院股份有限公司 用于疾病的早期检测的蛋白质冠传感器阵列的系统和方法
US20210072255A1 (en) 2016-12-16 2021-03-11 The Brigham And Women's Hospital, Inc. System and method for protein corona sensor array for early detection of diseases
GB201701572D0 (en) 2017-01-31 2017-03-15 Immunovia Ab Methods, arrays and uses thereof
KR102536314B1 (ko) * 2018-05-23 2023-05-25 주식회사 휴벳바이오 질환의 진단용 조성물
KR20260016611A (ko) 2018-11-07 2026-02-03 시어 인코퍼레이티드 단백질 코로나 분석을 위한 조성물, 방법 및 시스템 및 그것들의 용도
CN113454459A (zh) * 2019-02-18 2021-09-28 利物浦大学 诊断方法
JP7518852B2 (ja) 2019-03-26 2024-07-18 シアー, インコーポレイテッド 生物流体からのタンパク質コロナ分析のための組成物、方法およびシステム、ならびにそれらの使用
CN117169534A (zh) 2019-08-05 2023-12-05 禧尔公司 用于样品制备、数据生成和蛋白质冠分析的系统和方法
GB202010970D0 (en) 2020-07-16 2020-09-02 Immunovia Ab Methods, arrays and uses thereof
IL300826A (en) 2020-08-25 2023-04-01 Seer Inc Compositions and methods for testing proteins and nucleic acids
CN113655144A (zh) * 2021-08-09 2021-11-16 大连医科大学附属第一医院 一种基于丙酮酸激酶和α-2-HS-糖蛋白的早期预警重症急性胰腺炎的预测模型

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006113210A2 (en) 2005-04-13 2006-10-26 University Of Pittsburgh Diagnostic multimarker serological profiling
WO2007107774A2 (en) 2006-03-22 2007-09-27 Cartela R & D Ab Integrin alpha-10 subunit as therapeutic target and diagnostic/prognostic marker for cancer
WO2008117067A2 (en) 2007-03-27 2008-10-02 Carl Arne Krister Borrebaeck Protein signature/markers for the detection of adenocarcinoma
WO2009068857A1 (en) 2007-11-27 2009-06-04 Immunovia Ab Diagnostic methods and arrays for use in the same

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE12586T1 (de) 1980-05-02 1985-04-15 Edward P Davis Beinentlastungsgeraet.
US4486530A (en) 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US5856090A (en) 1994-09-09 1999-01-05 The Scripps Research Institute DNA-methylase linking reaction
GB9703369D0 (en) 1997-02-18 1997-04-09 Lindqvist Bjorn H Process
JP4194080B2 (ja) 2003-02-19 2008-12-10 茂 森村 膵癌検出用マーカー
US20060106119A1 (en) 2004-01-12 2006-05-18 Chang-Jie Guo Novel integration for CO and H2 recovery in gas to liquid processes
WO2006039671A2 (en) * 2004-09-29 2006-04-13 Central Institute For Experimental Animals Gene markers of tumor metastasis
US8383357B2 (en) 2005-03-16 2013-02-26 OSI Pharmaceuticals, LLC Biological markers predictive of anti-cancer response to epidermal growth factor receptor kinase inhibitors
EP1865981A2 (en) 2005-04-07 2007-12-19 Chiron Corporation Cacna1e in cancer diagnosis, detection and treatment
CA2604844A1 (en) 2005-04-07 2006-10-19 Novartis Vaccines And Diagnostics, Inc. Cancer-related genes
JP2007051880A (ja) 2005-08-15 2007-03-01 Tokyo Univ Of Science 膵臓癌の検出方法、膵臓癌の診断キット
KR100819122B1 (ko) * 2006-09-30 2008-04-04 남명진 췌장암 진단용 키트
WO2008079269A2 (en) 2006-12-19 2008-07-03 Genego, Inc. Novel methods for functional analysis of high-throughput experimental data and gene groups identified therfrom
CN102203295A (zh) * 2008-09-03 2011-09-28 约翰霍普金斯大学 胰腺肿瘤发生的通路及遗传性胰腺癌基因
US20120004289A1 (en) 2009-03-06 2012-01-05 The Johns Hopkins University Annexin a11 and associated genes as biomarkers for cancer
CN101880707A (zh) * 2009-05-05 2010-11-10 中国人民解放军第二军医大学 microRNA-21在鉴别胰腺癌中的应用
CN101613748A (zh) * 2009-06-09 2009-12-30 中国人民解放军第二军医大学 一种检测胰腺癌血清标志物的方法
SG168431A1 (en) * 2009-07-23 2011-02-28 Univ Singapore Cancer biomarker and the use thereof
GB201103726D0 (en) 2011-03-04 2011-04-20 Immunovia Ab Method, array and use thereof
GB201319878D0 (en) 2013-11-11 2013-12-25 Immunovia Ab Method, Array and use thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006113210A2 (en) 2005-04-13 2006-10-26 University Of Pittsburgh Diagnostic multimarker serological profiling
WO2007107774A2 (en) 2006-03-22 2007-09-27 Cartela R & D Ab Integrin alpha-10 subunit as therapeutic target and diagnostic/prognostic marker for cancer
WO2008117067A2 (en) 2007-03-27 2008-10-02 Carl Arne Krister Borrebaeck Protein signature/markers for the detection of adenocarcinoma
JP2010522875A (ja) * 2007-03-27 2010-07-08 イミュノヴィア・アーベー 腺癌の検出のための蛋白質シグネチャー/マーカー
WO2009068857A1 (en) 2007-11-27 2009-06-04 Immunovia Ab Diagnostic methods and arrays for use in the same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Chang Stephanie T et al, Journal of Translational Medicine (2009), vol. 7, no.1, pp. 105.
Grzesiak John J et al, Pancreas (2007), vol. 35, no.4, pp. 293-301.

Also Published As

Publication number Publication date
CN103534594A (zh) 2014-01-22
MX363201B (es) 2019-03-14
JP2014508298A (ja) 2014-04-03
JP6161542B2 (ja) 2017-07-12
CN107064518A (zh) 2017-08-18
WO2012120288A2 (en) 2012-09-13
KR20190101489A (ko) 2019-08-30
US9863960B2 (en) 2018-01-09
CA2828338A1 (en) 2012-09-13
US20140038844A1 (en) 2014-02-06
EP2681563A2 (en) 2014-01-08
MX2013010127A (es) 2014-10-15
GB201103726D0 (en) 2011-04-20
WO2012120288A3 (en) 2013-01-10
US20180136231A1 (en) 2018-05-17
KR20140040118A (ko) 2014-04-02
US20200088742A1 (en) 2020-03-19
US20210356478A1 (en) 2021-11-18

Similar Documents

Publication Publication Date Title
KR102014890B1 (ko) 췌장암의 존재를 결정하기 위한 방법, 어레이 및 그의 용도
US20220214344A1 (en) Method, array and use thereof
JP6465902B2 (ja) 腺癌の検出のための蛋白質シグネチャー/マーカー
US10564163B2 (en) Method, array and use thereof
CA2706786A1 (en) Diagnostic methods and arrays for use in the same
KR102208140B1 (ko) 전립선암의 바이오마커 검출에서 사용하기 위한 방법 및 어레이

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

A107 Divisional application of patent
GRNT Written decision to grant
PA0104 Divisional application for international application

St.27 status event code: A-0-1-A10-A18-div-PA0104

St.27 status event code: A-0-1-A10-A16-div-PA0104

PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20230822

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20230822

P22-X000 Classification modified

St.27 status event code: A-4-4-P10-P22-nap-X000