KR101968754B1 - 두타스테라이드 및 탐수로신 함유 경질 캡슐 복합제 및 그 제조방법 - Google Patents

두타스테라이드 및 탐수로신 함유 경질 캡슐 복합제 및 그 제조방법 Download PDF

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Publication number
KR101968754B1
KR101968754B1 KR1020170033369A KR20170033369A KR101968754B1 KR 101968754 B1 KR101968754 B1 KR 101968754B1 KR 1020170033369 A KR1020170033369 A KR 1020170033369A KR 20170033369 A KR20170033369 A KR 20170033369A KR 101968754 B1 KR101968754 B1 KR 101968754B1
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KR
South Korea
Prior art keywords
dutasteride
weight
probe
hard capsule
moiety
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KR1020170033369A
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English (en)
Korean (ko)
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KR20170107933A (ko
Inventor
이병준
김진철
김재호
김용일
박재현
우종수
Original Assignee
한미약품 주식회사
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Publication of KR20170107933A publication Critical patent/KR20170107933A/ko
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Publication of KR101968754B1 publication Critical patent/KR101968754B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020170033369A 2016-03-16 2017-03-16 두타스테라이드 및 탐수로신 함유 경질 캡슐 복합제 및 그 제조방법 KR101968754B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20160031468 2016-03-16
KR1020160031468 2016-03-16

Publications (2)

Publication Number Publication Date
KR20170107933A KR20170107933A (ko) 2017-09-26
KR101968754B1 true KR101968754B1 (ko) 2019-04-12

Family

ID=59850978

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020170033369A KR101968754B1 (ko) 2016-03-16 2017-03-16 두타스테라이드 및 탐수로신 함유 경질 캡슐 복합제 및 그 제조방법

Country Status (8)

Country Link
KR (1) KR101968754B1 (ru)
CN (1) CN109152743B (ru)
AU (1) AU2017233134A1 (ru)
BR (1) BR112018068686A2 (ru)
EA (1) EA201891843A1 (ru)
MX (1) MX2018011208A (ru)
PH (1) PH12018501985A1 (ru)
WO (1) WO2017160106A2 (ru)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006055659A2 (en) * 2004-11-15 2006-05-26 Smithkline Beecham Corporation Fixed dose combination op dutasteride and tamsulosin
KR101590072B1 (ko) * 2014-12-23 2016-01-29 한미약품 주식회사 두타스테라이드를 포함하는 자가유화 약물전달 시스템용 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW369521B (en) 1993-09-17 1999-09-11 Smithkline Beecham Corp Androstenone derivative
UA80393C2 (ru) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтическая композиция, которая содержит ингибитор фдэ 4, диспергированный в матрице
ES2287613T3 (es) * 2004-07-14 2007-12-16 Siegfried Generics International Ag Granulado para la liberacion controlada de tamsulosina, que contiene alginato.
CN102247379A (zh) * 2011-01-12 2011-11-23 北京润德康医药技术有限公司 一种复方制剂及其制备方法
CN102145007B (zh) * 2011-03-03 2013-03-20 王致中 一种非那雄胺软胶囊与盐酸坦索罗辛胶囊复方制剂、所用胶囊及制备方法
WO2014002015A1 (en) * 2012-06-25 2014-01-03 Ranbaxy Laboratories Limited Pharmaceutical composition comprising dutasteride
EP2976068B1 (en) * 2013-03-19 2018-05-30 Galenicum Health S.L. Pharmaceutical compositions comprising an active agent
CN105073100A (zh) * 2013-06-21 2015-11-18 沃克哈特有限公司 坦索罗辛或其盐的药物组合物
EP2949319A1 (en) * 2014-05-26 2015-12-02 Galenicum Health S.L. Pharmaceutical compositions comprising an active agent

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006055659A2 (en) * 2004-11-15 2006-05-26 Smithkline Beecham Corporation Fixed dose combination op dutasteride and tamsulosin
KR101590072B1 (ko) * 2014-12-23 2016-01-29 한미약품 주식회사 두타스테라이드를 포함하는 자가유화 약물전달 시스템용 조성물

Also Published As

Publication number Publication date
WO2017160106A2 (ko) 2017-09-21
MX2018011208A (es) 2019-05-30
CN109152743B (zh) 2022-01-07
BR112018068686A2 (pt) 2019-01-15
AU2017233134A1 (en) 2018-10-04
PH12018501985A1 (en) 2019-07-08
EA201891843A1 (ru) 2019-04-30
KR20170107933A (ko) 2017-09-26
CN109152743A (zh) 2019-01-04
WO2017160106A3 (ko) 2018-09-07

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