PH12018501985A1 - Dutasteride-and tamsulosin-containing hard capsule complex and preparation method therefor - Google Patents

Dutasteride-and tamsulosin-containing hard capsule complex and preparation method therefor

Info

Publication number
PH12018501985A1
PH12018501985A1 PH12018501985A PH12018501985A PH12018501985A1 PH 12018501985 A1 PH12018501985 A1 PH 12018501985A1 PH 12018501985 A PH12018501985 A PH 12018501985A PH 12018501985 A PH12018501985 A PH 12018501985A PH 12018501985 A1 PH12018501985 A1 PH 12018501985A1
Authority
PH
Philippines
Prior art keywords
dutasteride
tamsulosin
independent part
hard capsule
preparation
Prior art date
Application number
PH12018501985A
Inventor
Benjamin Joon Lee
Jin Cheul Kim
Jae Ho Kim
Yong Il Kim
Jae Hyun Park
Jong Soo Woo
Original Assignee
Hanmi Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd
Publication of PH12018501985A1 publication Critical patent/PH12018501985A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

An aspect of the present invention provides a hard capsule complex and a preparation method therefor, the hard capsule complex comprising, in a separate state: a dutasteride independent part comprising a dutasteride or a pharmaceutically acceptable salt thereof; and a tamsulosin independent part comprising a tamsulosin or a pharmaceutically acceptable salt thereof, wherein the dutasteride independent part is a preparation containing a self-emulsifying emulsion consisting of a dutasteride, an oil and a surfactant; the tamsulosin independent part is a solid preparation containing a sustained-release agent; the dutasteride independent part and the tamsulosin independent part are included in a separate state and can be filled into capsules 0 to 3.
PH12018501985A 2016-03-16 2018-09-14 Dutasteride-and tamsulosin-containing hard capsule complex and preparation method therefor PH12018501985A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20160031468 2016-03-16
PCT/KR2017/002862 WO2017160106A2 (en) 2016-03-16 2017-03-16 Dutasteride- and tamsulosin-containing hard capsule complex and preparation method therefor

Publications (1)

Publication Number Publication Date
PH12018501985A1 true PH12018501985A1 (en) 2019-07-08

Family

ID=59850978

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12018501985A PH12018501985A1 (en) 2016-03-16 2018-09-14 Dutasteride-and tamsulosin-containing hard capsule complex and preparation method therefor

Country Status (8)

Country Link
KR (1) KR101968754B1 (en)
CN (1) CN109152743B (en)
AU (1) AU2017233134A1 (en)
BR (1) BR112018068686A2 (en)
EA (1) EA201891843A1 (en)
MX (1) MX2018011208A (en)
PH (1) PH12018501985A1 (en)
WO (1) WO2017160106A2 (en)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW369521B (en) 1993-09-17 1999-09-11 Smithkline Beecham Corp Androstenone derivative
UA80393C2 (en) 2000-12-07 2007-09-25 Алтана Фарма Аг Pharmaceutical preparation comprising an pde inhibitor dispersed on a matrix
EP1618873B1 (en) * 2004-07-14 2007-06-06 Siegfried Generics International AG Granule for the controlled release of tamsulosin, containing alginate
WO2006055659A2 (en) * 2004-11-15 2006-05-26 Smithkline Beecham Corporation Fixed dose combination op dutasteride and tamsulosin
CN102247379A (en) * 2011-01-12 2011-11-23 北京润德康医药技术有限公司 Compound preparation and preparation method thereof
CN102145007B (en) * 2011-03-03 2013-03-20 王致中 Finasteride soft capsule and amsulosin hydrochloride capsule compound preparation, used capsule and preparing method
WO2014002015A1 (en) * 2012-06-25 2014-01-03 Ranbaxy Laboratories Limited Pharmaceutical composition comprising dutasteride
WO2014147096A1 (en) * 2013-03-19 2014-09-25 Galenicum Health S.L. Pharmaceutical compositions comprising an active agent
CN105073100A (en) * 2013-06-21 2015-11-18 沃克哈特有限公司 Pharmaceutical compositions of tamsulosin or salts thereof
ES2555485T1 (en) * 2014-05-26 2016-01-04 Galenicum Health S.L. Pharmaceutical compositions containing an active agent
KR101590072B1 (en) * 2014-12-23 2016-01-29 한미약품 주식회사 Composition for self-emulsifying drug delivery system comprising dutasteride

Also Published As

Publication number Publication date
MX2018011208A (en) 2019-05-30
WO2017160106A3 (en) 2018-09-07
BR112018068686A2 (en) 2019-01-15
CN109152743B (en) 2022-01-07
CN109152743A (en) 2019-01-04
KR101968754B1 (en) 2019-04-12
EA201891843A1 (en) 2019-04-30
KR20170107933A (en) 2017-09-26
AU2017233134A1 (en) 2018-10-04
WO2017160106A2 (en) 2017-09-21

Similar Documents

Publication Publication Date Title
AR102767A1 (en) EZH2 INHIBITORS
EA201992020A1 (en) PHARMACEUTICAL COMBINED COMPOSITION OF CAPSULES CONTAINING TADALAFIL AND TAMSULOSIN
EP3117838A4 (en) Composition containing sophorolipid, physiologically active substance and oil and fat, and method of producing said composition
MX2021001905A (en) Pharmaceutical preparation having excellent dissolution properties, containing esomeprazole and sodium bicarbonate.
TW201613632A (en) Brain function improving agent, and prophylactic or therapeutic agent for cognitive dysfunction
IN2014MU01042A (en)
MX2017003082A (en) Abuse resistant pharmaceutical compositions.
PT3721718T (en) Three-layered capsule composed of non-hydrogenated fat, and method for manufacturing same
IL291953A (en) Non-animal softgel capsule formulations, methods of preparation, and methods of use thereof
PH12019500919A1 (en) Esomeprazole~containing complex capsule and preparation method therefor
PH12018501985A1 (en) Dutasteride-and tamsulosin-containing hard capsule complex and preparation method therefor
PH12019501327A1 (en) Umami taste enhancing agent
EP3416626A4 (en) Microspheres containing therapeutic agents and related methods of use
EA201590474A1 (en) PHARMACEUTICAL COMPOSITION BASED ON COMPOSITE CAPSULES INCLUDING IRBESARTAN AND HMG-COA REDUCTASE INHIBITOR
EP3648745A4 (en) Pharmaceutical composition including multi-unit spheroidal tablet containing esomeprazole and spheroidal pharmaceutically acceptable salt thereof, and method of preparing the pharmaceutical composition
EA202090913A1 (en) COMPOSITION OF MODIFIED RELEASE TABLETS CONTAINING MIRABEGRON
MY190876A (en) Composite capsules comprising raloxifene, and vitamin d or its derivatives
TN2014000152A1 (en) Sustained-release preparation
IT201700037229A1 (en) DEVICE FOR THE OPENING OF CAPSULES CONTAINING PREPARED BEVERAGES
GR20150100035A (en) Pharmaceutical aprepitant-containing formulation and preparation method thereof
TH165164B (en) Pharmaceutical compound formulation of capsules containing tadalafil. And tamsulosin
MX2015011152A (en) Omeprazole-sodium bicarbonate pharmaceutical composition to integrate a capsule for the treatment of heartburn related allopathies.
TH165164A (en) Pharmaceutical compound formulation of capsules containing tadalafil. And tamsulosin
MX2020012408A (en) Novel pharmaceutical composition of tamsulosin and dutasteride.
PL439306A1 (en) Liposomal preparation of zinc and copper and method of preparing it