KR101953181B1 - 관절증 치료제 - Google Patents

관절증 치료제 Download PDF

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Publication number
KR101953181B1
KR101953181B1 KR1020147015608A KR20147015608A KR101953181B1 KR 101953181 B1 KR101953181 B1 KR 101953181B1 KR 1020147015608 A KR1020147015608 A KR 1020147015608A KR 20147015608 A KR20147015608 A KR 20147015608A KR 101953181 B1 KR101953181 B1 KR 101953181B1
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KR
South Korea
Prior art keywords
group
arthrosis
phosphatidic acid
expression
carbon atoms
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KR1020147015608A
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English (en)
Korean (ko)
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KR20140098778A (ko
Inventor
키미코 무로후시
이쿠코 마스다
토시로 모로호시
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산쇼가부시키가이샤
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020147015608A 2011-11-11 2012-10-12 관절증 치료제 Active KR101953181B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011247047 2011-11-11
JPJP-P-2011-247047 2011-11-11
PCT/JP2012/076478 WO2013069404A1 (ja) 2011-11-11 2012-10-12 関節症治療剤

Publications (2)

Publication Number Publication Date
KR20140098778A KR20140098778A (ko) 2014-08-08
KR101953181B1 true KR101953181B1 (ko) 2019-02-28

Family

ID=48289788

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147015608A Active KR101953181B1 (ko) 2011-11-11 2012-10-12 관절증 치료제

Country Status (15)

Country Link
US (1) US9085593B2 (enExample)
EP (1) EP2803359B1 (enExample)
JP (1) JP5465815B2 (enExample)
KR (1) KR101953181B1 (enExample)
CN (1) CN103906519B (enExample)
AU (1) AU2012337087B2 (enExample)
BR (1) BR112014011315B8 (enExample)
CA (1) CA2855660C (enExample)
ES (1) ES2634008T3 (enExample)
IN (1) IN2014CN04222A (enExample)
MY (1) MY168931A (enExample)
PH (1) PH12014501058B1 (enExample)
RU (1) RU2646457C2 (enExample)
SG (1) SG11201402226PA (enExample)
WO (1) WO2013069404A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3483169B1 (en) 2014-08-12 2021-05-26 Otsuka Chemical Co., Ltd. Crystal of cyclic phosphonic acid sodium salt and method for manufacturing same
JP6727596B1 (ja) 2019-11-22 2020-07-22 国立大学法人お茶の水女子大学 カルバリゾホスファチジン酸
TWI868287B (zh) 2019-12-23 2025-01-01 日商大塚化學股份有限公司 carba-環狀磷脂酸化合物
JP7736256B2 (ja) * 2020-11-13 2025-09-09 株式会社マツモト交商 環状ホスファチジン酸含有組成物及び美容方法
EP4252756A4 (en) * 2020-11-26 2024-10-16 Sansho Co., Ltd. THERAPEUTIC AGENT FOR PULMONARY FIBROSIS

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004010582A (ja) 2002-06-11 2004-01-15 Gencom Co カルバ環状ホスファチジン酸誘導体
JP2010189315A (ja) 2009-02-18 2010-09-02 Unitika Ltd 関節軟骨損傷治癒促進剤及びそれを含有する飲食品

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2700350B2 (ja) 1990-04-20 1998-01-21 小糸工業株式会社 車両感知器
JP3195833B2 (ja) 1991-09-30 2001-08-06 きみ子 室伏 新規生理活性物質及びその製造法
JPH07149772A (ja) * 1993-11-26 1995-06-13 Sagami Chem Res Center タンパク質リン酸化酵素ｃの活性促進剤
JPH07258278A (ja) 1994-03-18 1995-10-09 Sagami Chem Res Center １−Ｏ−アシルグリセロール−２，３−ホスフェート誘導体を有効成分とするＤＮＡポリメラーゼαの阻害剤
JPH0925235A (ja) 1995-07-13 1997-01-28 Sagami Chem Res Center １−ｏ−アシルグリセロール−２，３−ホスフェート誘導体を有効成分とするがん転移抑制剤
JP2001178489A (ja) 1999-12-24 2001-07-03 Kimiko Murofushi 環状ホスファチジン酸の製造法
JP4836345B2 (ja) * 2001-04-13 2011-12-14 きみ子 室伏 環状ホスファチジン酸誘導体を含む神経細胞の生存促進剤
JP4815063B2 (ja) * 2001-04-13 2011-11-16 きみ子 室伏 環状ホスファチジン酸を含むグリア細胞の増殖、分化及び／又は生存の促進のための薬剤
US20040214799A1 (en) * 2001-05-21 2004-10-28 Mutsuko Mukai Cancerous metastasis inhibitors containing carbacyclic phosphatidic acid derivatives
RU2240131C1 (ru) * 2003-04-04 2004-11-20 Аладьев Сергей Иванович Средство "артровит" для профилактики и лечения артритов и артрозов
EP1613298A4 (en) * 2003-04-11 2007-10-03 Univ Tennessee Res Foundation Lysophosphatidic Acid Analysis and Inhibition of Neointimal Formation
CN101163692B (zh) 2005-02-16 2012-01-18 先灵公司 具有cxcr3拮抗活性的杂环取代的哌嗪
KR20090097943A (ko) * 2006-12-28 2009-09-16 오짜노미즈 유니버시티 환상 포스파티딘산 유도체를 포함하는 진통제

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004010582A (ja) 2002-06-11 2004-01-15 Gencom Co カルバ環状ホスファチジン酸誘導体
JP2010189315A (ja) 2009-02-18 2010-09-02 Unitika Ltd 関節軟骨損傷治癒促進剤及びそれを含有する飲食品

Also Published As

Publication number Publication date
ES2634008T3 (es) 2017-09-26
IN2014CN04222A (enExample) 2015-07-17
JP5465815B2 (ja) 2014-04-09
EP2803359A1 (en) 2014-11-19
CN103906519B (zh) 2017-10-10
JPWO2013069404A1 (ja) 2015-04-02
HK1199406A1 (en) 2015-07-03
RU2014123690A (ru) 2015-12-20
EP2803359A4 (en) 2015-12-16
WO2013069404A1 (ja) 2013-05-16
PH12014501058B1 (en) 2019-11-08
BR112014011315B8 (pt) 2020-09-15
CA2855660A1 (en) 2013-05-16
RU2646457C2 (ru) 2018-03-05
NZ624870A (en) 2016-01-29
BR112014011315A2 (pt) 2017-05-09
EP2803359B1 (en) 2017-04-19
SG11201402226PA (en) 2014-10-30
MY168931A (en) 2019-01-09
US20140309194A1 (en) 2014-10-16
AU2012337087A1 (en) 2014-06-05
CN103906519A (zh) 2014-07-02
US9085593B2 (en) 2015-07-21
PH12014501058A1 (en) 2014-06-23
KR20140098778A (ko) 2014-08-08
AU2012337087B2 (en) 2016-11-17
BR112014011315B1 (pt) 2020-03-03
CA2855660C (en) 2019-04-16

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