RU2646457C2 - Терапевтическое средство при артрозе - Google Patents

Терапевтическое средство при артрозе Download PDF

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Publication number
RU2646457C2
RU2646457C2 RU2014123690A RU2014123690A RU2646457C2 RU 2646457 C2 RU2646457 C2 RU 2646457C2 RU 2014123690 A RU2014123690 A RU 2014123690A RU 2014123690 A RU2014123690 A RU 2014123690A RU 2646457 C2 RU2646457 C2 RU 2646457C2
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RU
Russia
Prior art keywords
group
arthrosis
hind limb
formula
phosphatidic acid
Prior art date
Application number
RU2014123690A
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English (en)
Russian (ru)
Other versions
RU2014123690A (ru
Inventor
Кимико МУРОФУСИ
Икуко МАСУДА
Тосиро МОРОХОСИ
Original Assignee
Сансо Ко. Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Сансо Ко. Лтд. filed Critical Сансо Ко. Лтд.
Publication of RU2014123690A publication Critical patent/RU2014123690A/ru
Application granted granted Critical
Publication of RU2646457C2 publication Critical patent/RU2646457C2/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2014123690A 2011-11-11 2012-10-12 Терапевтическое средство при артрозе RU2646457C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011247047 2011-11-11
JP2011-247047 2011-11-11
PCT/JP2012/076478 WO2013069404A1 (ja) 2011-11-11 2012-10-12 関節症治療剤

Publications (2)

Publication Number Publication Date
RU2014123690A RU2014123690A (ru) 2015-12-20
RU2646457C2 true RU2646457C2 (ru) 2018-03-05

Family

ID=48289788

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2014123690A RU2646457C2 (ru) 2011-11-11 2012-10-12 Терапевтическое средство при артрозе

Country Status (15)

Country Link
US (1) US9085593B2 (enExample)
EP (1) EP2803359B1 (enExample)
JP (1) JP5465815B2 (enExample)
KR (1) KR101953181B1 (enExample)
CN (1) CN103906519B (enExample)
AU (1) AU2012337087B2 (enExample)
BR (1) BR112014011315B8 (enExample)
CA (1) CA2855660C (enExample)
ES (1) ES2634008T3 (enExample)
IN (1) IN2014CN04222A (enExample)
MY (1) MY168931A (enExample)
PH (1) PH12014501058B1 (enExample)
RU (1) RU2646457C2 (enExample)
SG (1) SG11201402226PA (enExample)
WO (1) WO2013069404A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3483169B1 (en) 2014-08-12 2021-05-26 Otsuka Chemical Co., Ltd. Crystal of cyclic phosphonic acid sodium salt and method for manufacturing same
JP6727596B1 (ja) 2019-11-22 2020-07-22 国立大学法人お茶の水女子大学 カルバリゾホスファチジン酸
TWI868287B (zh) 2019-12-23 2025-01-01 日商大塚化學股份有限公司 carba-環狀磷脂酸化合物
JP7736256B2 (ja) * 2020-11-13 2025-09-09 株式会社マツモト交商 環状ホスファチジン酸含有組成物及び美容方法
EP4252756A4 (en) * 2020-11-26 2024-10-16 Sansho Co., Ltd. THERAPEUTIC AGENT FOR PULMONARY FIBROSIS

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002083149A1 (fr) * 2001-04-13 2002-10-24 Gencom Corporation Medicaments contenant un acide phosphatique cyclique et favorisant la proliferation, la differentiation et/ou la survie de cellules gliales
WO2002083148A1 (fr) * 2001-04-13 2002-10-24 Gencom Corporation Promoteurs de survie des cellules nerveuses a base de derive cyclique d'acide phosphatidique
WO2002094286A1 (fr) * 2001-05-21 2002-11-28 Gencom Corporation Inhibiteurs de metastases cancereuses contenant des derives d'acide phosphatidique carbacycliques
WO2003104246A1 (ja) * 2002-06-11 2003-12-18 株式会社ジェンコム カルバ環状ホスファチジン酸誘導体
WO2004091496A2 (en) * 2003-04-11 2004-10-28 The University Of Tennessee Research Foundation Lysophosphatidic acid analogs and inhibition of neointima formation
RU2240131C1 (ru) * 2003-04-04 2004-11-20 Аладьев Сергей Иванович Средство "артровит" для профилактики и лечения артритов и артрозов

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2700350B2 (ja) 1990-04-20 1998-01-21 小糸工業株式会社 車両感知器
JP3195833B2 (ja) 1991-09-30 2001-08-06 きみ子 室伏 新規生理活性物質及びその製造法
JPH07149772A (ja) * 1993-11-26 1995-06-13 Sagami Chem Res Center タンパク質リン酸化酵素ｃの活性促進剤
JPH07258278A (ja) 1994-03-18 1995-10-09 Sagami Chem Res Center １−Ｏ−アシルグリセロール−２，３−ホスフェート誘導体を有効成分とするＤＮＡポリメラーゼαの阻害剤
JPH0925235A (ja) 1995-07-13 1997-01-28 Sagami Chem Res Center １−ｏ−アシルグリセロール−２，３−ホスフェート誘導体を有効成分とするがん転移抑制剤
JP2001178489A (ja) 1999-12-24 2001-07-03 Kimiko Murofushi 環状ホスファチジン酸の製造法
CN101163692B (zh) 2005-02-16 2012-01-18 先灵公司 具有cxcr3拮抗活性的杂环取代的哌嗪
KR20090097943A (ko) * 2006-12-28 2009-09-16 오짜노미즈 유니버시티 환상 포스파티딘산 유도체를 포함하는 진통제
JP2010189315A (ja) * 2009-02-18 2010-09-02 Unitika Ltd 関節軟骨損傷治癒促進剤及びそれを含有する飲食品

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002083149A1 (fr) * 2001-04-13 2002-10-24 Gencom Corporation Medicaments contenant un acide phosphatique cyclique et favorisant la proliferation, la differentiation et/ou la survie de cellules gliales
WO2002083148A1 (fr) * 2001-04-13 2002-10-24 Gencom Corporation Promoteurs de survie des cellules nerveuses a base de derive cyclique d'acide phosphatidique
WO2002094286A1 (fr) * 2001-05-21 2002-11-28 Gencom Corporation Inhibiteurs de metastases cancereuses contenant des derives d'acide phosphatidique carbacycliques
WO2003104246A1 (ja) * 2002-06-11 2003-12-18 株式会社ジェンコム カルバ環状ホスファチジン酸誘導体
RU2240131C1 (ru) * 2003-04-04 2004-11-20 Аладьев Сергей Иванович Средство "артровит" для профилактики и лечения артритов и артрозов
WO2004091496A2 (en) * 2003-04-11 2004-10-28 The University Of Tennessee Research Foundation Lysophosphatidic acid analogs and inhibition of neointima formation

Also Published As

Publication number Publication date
ES2634008T3 (es) 2017-09-26
IN2014CN04222A (enExample) 2015-07-17
JP5465815B2 (ja) 2014-04-09
EP2803359A1 (en) 2014-11-19
CN103906519B (zh) 2017-10-10
JPWO2013069404A1 (ja) 2015-04-02
HK1199406A1 (en) 2015-07-03
RU2014123690A (ru) 2015-12-20
EP2803359A4 (en) 2015-12-16
WO2013069404A1 (ja) 2013-05-16
PH12014501058B1 (en) 2019-11-08
BR112014011315B8 (pt) 2020-09-15
CA2855660A1 (en) 2013-05-16
NZ624870A (en) 2016-01-29
BR112014011315A2 (pt) 2017-05-09
EP2803359B1 (en) 2017-04-19
SG11201402226PA (en) 2014-10-30
MY168931A (en) 2019-01-09
US20140309194A1 (en) 2014-10-16
AU2012337087A1 (en) 2014-06-05
KR101953181B1 (ko) 2019-02-28
CN103906519A (zh) 2014-07-02
US9085593B2 (en) 2015-07-21
PH12014501058A1 (en) 2014-06-23
KR20140098778A (ko) 2014-08-08
AU2012337087B2 (en) 2016-11-17
BR112014011315B1 (pt) 2020-03-03
CA2855660C (en) 2019-04-16

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