KR101947352B1 - 인지 건강 및 기능을 향상시키는 식물 추출물 - Google Patents

인지 건강 및 기능을 향상시키는 식물 추출물 Download PDF

Info

Publication number
KR101947352B1
KR101947352B1 KR1020157006128A KR20157006128A KR101947352B1 KR 101947352 B1 KR101947352 B1 KR 101947352B1 KR 1020157006128 A KR1020157006128 A KR 1020157006128A KR 20157006128 A KR20157006128 A KR 20157006128A KR 101947352 B1 KR101947352 B1 KR 101947352B1
Authority
KR
South Korea
Prior art keywords
memory
cognitive
composition
learning
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020157006128A
Other languages
English (en)
Korean (ko)
Other versions
KR20150041654A (ko
Inventor
미셀 세디아
켈리 헤어링거
브랜든 루이스
해리 펭
Original Assignee
케민 인더스트리즈, 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 케민 인더스트리즈, 인코포레이티드 filed Critical 케민 인더스트리즈, 인코포레이티드
Publication of KR20150041654A publication Critical patent/KR20150041654A/ko
Application granted granted Critical
Publication of KR101947352B1 publication Critical patent/KR101947352B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
KR1020157006128A 2012-08-09 2013-08-09 인지 건강 및 기능을 향상시키는 식물 추출물 Active KR101947352B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261681414P 2012-08-09 2012-08-09
US61/681,414 2012-08-09
PCT/US2013/054274 WO2014026081A1 (en) 2012-08-09 2013-08-09 Plant extracts for improving cognitive health and function

Publications (2)

Publication Number Publication Date
KR20150041654A KR20150041654A (ko) 2015-04-16
KR101947352B1 true KR101947352B1 (ko) 2019-02-12

Family

ID=50066333

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157006128A Active KR101947352B1 (ko) 2012-08-09 2013-08-09 인지 건강 및 기능을 향상시키는 식물 추출물

Country Status (11)

Country Link
US (2) US20140044813A1 (enExample)
EP (1) EP2882443B1 (enExample)
JP (4) JP2015524484A (enExample)
KR (1) KR101947352B1 (enExample)
CN (2) CN111358832A (enExample)
AU (1) AU2013299491B2 (enExample)
BR (1) BR112015002739A2 (enExample)
CA (1) CA2880708C (enExample)
ES (1) ES2715005T3 (enExample)
PL (1) PL2882443T3 (enExample)
WO (1) WO2014026081A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200134170A (ko) * 2019-05-21 2020-12-01 건국대학교 글로컬산학협력단 클로로필 및 로즈마린산을 포함하는 미세먼지에 의해 유발된 신경염증 또는 신경 퇴행성 질환의 예방 또는 치료용 조성물

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160113277A (ko) * 2014-01-30 2016-09-28 케민 인더스트리즈, 인코포레이티드 인지 기능을 개선시키기 위한 식물 추출물
BR112017005133A2 (pt) * 2014-09-15 2018-01-23 Kemin Ind Inc métodos para intensificar, melhorar ou manter saúde e/ou função cognitiva, para tratar ou prevenir um declínio na saúde e/ou função cognitiva, e para melhorar humor e sono em um mamífero
EP3204026A1 (en) * 2014-10-08 2017-08-16 Abbott Laboratories Nutritional compositions comprising an oxidizable component and water-soluble plant extract
US20180133275A1 (en) * 2016-11-11 2018-05-17 Kemin Industries, Inc. Use of botanical extracts for improving brain health through enhanced neurogenesis
CN106727915B (zh) * 2017-01-18 2020-03-31 云南德彩堂生物医药科技有限公司 一种稳定高效提高记忆的组合物及其制备方法和应用
SG11202003879RA (en) * 2017-10-30 2020-05-28 Neuropore Therapies Inc Substituted phenyl sulfonyl phenyl triazole thiones and uses thereof
CN109602759B (zh) * 2019-01-17 2020-10-09 广西医科大学 罗汉松实多糖的用途
CN110463846A (zh) * 2019-07-30 2019-11-19 河南科技学院 留兰香提取物在制备抗宠物衰老药物或宠物食品中的应用
JP7330630B2 (ja) * 2019-11-20 2023-08-22 株式会社ニップン ロスマリン酸及びカルノシン酸を有効成分とする神経突起伸長誘導作用を有する組成物
JP2022104122A (ja) * 2020-12-28 2022-07-08 株式会社ニップン オキシトシン関連シグナル活性化剤
CN120152704A (zh) * 2022-10-27 2025-06-13 凯敏工业公司 留兰香提取物在视网膜神经营养中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69930619T2 (de) * 1998-05-16 2006-12-28 Mogam Biotechnology Research Institute, Yongin Verwendung von rosmarinsäure und deren derivate als immunsuppressor oder als inhibitor von sh-2 vermittelten prozessen
JP4629822B2 (ja) * 1999-12-02 2011-02-09 長瀬産業株式会社 神経成長因子合成促進剤
JP2006199666A (ja) * 2005-01-24 2006-08-03 Nagase & Co Ltd 健忘症の予防・治療剤
WO2007047978A2 (en) * 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by pde inhibition
EP1930019A1 (en) * 2006-11-24 2008-06-11 DSMIP Assets B.V. Rosemary extracts, dietary and pharmaceutical compositions containing them and their uses
EP1925213A1 (en) * 2006-11-24 2008-05-28 DSMIP Assets B.V. Dietary and pharmaceutical compositions comprising a sage extract comprising a mixture of tricyclic diterpenes and their derivatives and their uses
US20100137433A1 (en) * 2007-01-24 2010-06-03 Laima Kott Production of Rosmarinic Acid from Spearmint and uses Thereof
US7972633B2 (en) * 2007-02-07 2011-07-05 Applied Cognitive Sciences, LLC Nutritional supplements for healthy memory and mental function
EP2060192B9 (en) * 2007-10-17 2016-05-04 Rudolf Wild GmbH & Co. KG Composition comprising lemon balm extracts
JP5712207B2 (ja) * 2009-06-12 2015-05-07 ジェネレックス ファーマシューティカルズ インコーポレイテッド 脳疾患及び状態の予防及び治療のための組成物及び方法
CN101773488A (zh) * 2010-02-10 2010-07-14 青岛大学 一种基于迷迭香酸的药物及其在治疗帕金森病中的应用
JP2011256118A (ja) * 2010-06-07 2011-12-22 Kao Corp Ｉｌ−８及びｇｍ−ｃｓｆ発現抑制剤

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Behavioural Brain Research 180 (2007) 139-145*

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200134170A (ko) * 2019-05-21 2020-12-01 건국대학교 글로컬산학협력단 클로로필 및 로즈마린산을 포함하는 미세먼지에 의해 유발된 신경염증 또는 신경 퇴행성 질환의 예방 또는 치료용 조성물
KR102421772B1 (ko) * 2019-05-21 2022-07-18 건국대학교 글로컬산학협력단 클로로필 및 로즈마린산을 포함하는 미세먼지에 의해 유발된 신경염증 또는 신경 퇴행성 질환의 예방 또는 치료용 조성물

Also Published As

Publication number Publication date
EP2882443B1 (en) 2019-01-16
US20250009703A1 (en) 2025-01-09
BR112015002739A2 (pt) 2017-07-04
CN111358832A (zh) 2020-07-03
EP2882443A1 (en) 2015-06-17
JP2025029029A (ja) 2025-03-05
ES2715005T3 (es) 2019-05-31
WO2014026081A1 (en) 2014-02-13
CA2880708A1 (en) 2014-02-13
CA2880708C (en) 2023-09-26
US20140044813A1 (en) 2014-02-13
JP2015524484A (ja) 2015-08-24
EP2882443A4 (en) 2016-01-06
JP2023027232A (ja) 2023-03-01
PL2882443T3 (pl) 2019-06-28
KR20150041654A (ko) 2015-04-16
JP2021066735A (ja) 2021-04-30
AU2013299491A1 (en) 2015-02-12
CN104684562A (zh) 2015-06-03
AU2013299491B2 (en) 2018-03-15

Similar Documents

Publication Publication Date Title
KR101947352B1 (ko) 인지 건강 및 기능을 향상시키는 식물 추출물
Farr et al. Effect of botanical extracts containing carnosic acid or rosmarinic acid on learning and memory in SAMP8 mice
Mecocci et al. Antioxidant clinical trials in mild cognitive impairment and Alzheimer's disease
Umukoro et al. Naringenin attenuates behavioral derangements induced by social defeat stress in mice via inhibition of acetylcholinesterase activity, oxidative stress and release of pro-inflammatory cytokines
Aboul Ezz et al. The neuroprotective effect of curcumin and Nigella sativa oil against oxidative stress in the pilocarpine model of epilepsy: a comparison with valproate
Jangra et al. Hesperidin and silibinin ameliorate aluminum-induced neurotoxicity: modulation of antioxidants and inflammatory cytokines level in mice hippocampus
Di Domenico et al. Strategy to reduce free radical species in Alzheimer’s disease: an update of selected antioxidants
Mizrahi et al. Pomegranate seed oil nanoemulsions for the prevention and treatment of neurodegenerative diseases: the case of genetic CJD
Lin et al. Carnosic acid protects SH-SY5Y cells against 6-hydroxydopamine-induced cell death through upregulation of parkin pathway
Srivastava et al. Protective effect of curcumin by modulating BDNF/DARPP32/CREB in arsenic-induced alterations in dopaminergic signaling in rat corpus striatum
Vassallo et al. Mediterranean diet and dementia of the Alzheimer type
Smach et al. Effects of sage extract on memory performance in mice and acetylcholinesterase activity
Alam et al. Neuroprotective potential of adenyl cyclase/cAMP/CREB and mitochondrial CoQ10 activator in amyotrophic lateral sclerosis rats
Cuciniello et al. Conjugated linoleic acid downregulates Alzheimer's hallmarks in aluminum mouse model through an Nrf2-mediated adaptive response and increases brain glucose transporter levels
Mohamed et al. Evaluation of anti-Alzheimer activity of Echinacea purpurea extracts in aluminum chloride-induced neurotoxicity in rat model
Moradi Vastegani et al. Anethole attenuates motor dysfunctions, striatal neuronal activity deficiency and blood brain barrier permeability by decreasing striatal α-synuclein and oxidative stress in rotenone-induced Parkinson’s disease of male rats
Cho et al. Neuroprotective effects of Actinidia eriantha cv. Bidan kiwifruit on amyloid beta-induced neuronal damages in PC-12 cells and ICR mice
Chatterjee et al. Exploring pathological targets and advancing pharmacotherapy in autism spectrum disorder: contributions of glial cells and heavy metals
Boldrini et al. Potential use of modulators of oxidative stress as add-on therapy in patients with anxiety disorders
Yan et al. Dietary beta-hydroxybutyrate is superior to a ketogenic diet to improve behavior and abnormal myelination in a mouse model of NMDA receptor deficiency
Mecocci et al. Antioxidant agents in Alzheimer's disease
Li et al. Neuroprotective Role of Periplocin Against Aluminium Chloride-stimulated Alzheimer's Disease in a Rat Model by Modulation of Oxidative Stress and Inflammation.
Reddy Neuroprotective effects of Abelmoschus moschatus seed extract on fluoride-induced myelin degeneration in developing brain of rats
Marques Role of nutrition in adult neurogenesis
Gu et al. Effects of plant-derived dietary antioxidants on Alzheimer's disease: Focus on ferroptosis

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20150309

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20180705

Comment text: Request for Examination of Application

PA0302 Request for accelerated examination

Patent event date: 20180705

Patent event code: PA03022R01D

Comment text: Request for Accelerated Examination

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20181015

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20190107

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20190205

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20190207

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
PR1001 Payment of annual fee

Payment date: 20220128

Start annual number: 4

End annual number: 4

PR1001 Payment of annual fee

Payment date: 20230126

Start annual number: 5

End annual number: 5

PR1001 Payment of annual fee

Payment date: 20240130

Start annual number: 6

End annual number: 6

PR1001 Payment of annual fee

Payment date: 20250124

Start annual number: 7

End annual number: 7