KR101919269B1 - 데옥시콜린산 및 그의 염들의 제형물들 - Google Patents

데옥시콜린산 및 그의 염들의 제형물들 Download PDF

Info

Publication number
KR101919269B1
KR101919269B1 KR1020177016779A KR20177016779A KR101919269B1 KR 101919269 B1 KR101919269 B1 KR 101919269B1 KR 1020177016779 A KR1020177016779 A KR 1020177016779A KR 20177016779 A KR20177016779 A KR 20177016779A KR 101919269 B1 KR101919269 B1 KR 101919269B1
Authority
KR
South Korea
Prior art keywords
sodium deoxycholate
aqueous solution
sodium
deoxycholic acid
solution
Prior art date
Application number
KR1020177016779A
Other languages
English (en)
Korean (ko)
Other versions
KR20170075016A (ko
Inventor
로버트 에밀 호지
제프리 더글라스 웹스터
로버트 엠. 모리어티
Original Assignee
키쎄라 바이오파마슈티컬즈 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45569726&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR101919269(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 키쎄라 바이오파마슈티컬즈 인코포레이티드 filed Critical 키쎄라 바이오파마슈티컬즈 인코포레이티드
Publication of KR20170075016A publication Critical patent/KR20170075016A/ko
Application granted granted Critical
Publication of KR101919269B1 publication Critical patent/KR101919269B1/ko

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
KR1020177016779A 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들 KR101919269B1 (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2011/048806 WO2013028177A1 (en) 2011-08-23 2011-08-23 Formulations of deoxycholic acid and salts thereof

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020147006855A Division KR101751585B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020187032491A Division KR102034606B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들

Publications (2)

Publication Number Publication Date
KR20170075016A KR20170075016A (ko) 2017-06-30
KR101919269B1 true KR101919269B1 (ko) 2018-11-15

Family

ID=45569726

Family Applications (5)

Application Number Title Priority Date Filing Date
KR1020207002722A KR20200013103A (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020177016779A KR101919269B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020197030233A KR102073536B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020147006855A KR101751585B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020187032491A KR102034606B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1020207002722A KR20200013103A (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들

Family Applications After (3)

Application Number Title Priority Date Filing Date
KR1020197030233A KR102073536B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020147006855A KR101751585B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020187032491A KR102034606B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들

Country Status (18)

Country Link
JP (1) JP5919597B2 (ru)
KR (5) KR20200013103A (ru)
CN (3) CN103826608A (ru)
AU (3) AU2011375432B2 (ru)
BR (1) BR112014000547B1 (ru)
CA (1) CA2842177C (ru)
CR (1) CR20140053A (ru)
EA (1) EA029305B1 (ru)
IL (1) IL230547A (ru)
IN (1) IN2014CN02188A (ru)
MX (1) MX350390B (ru)
MY (1) MY184277A (ru)
NZ (1) NZ620040A (ru)
PH (1) PH12016501175A1 (ru)
SG (1) SG2014013205A (ru)
UA (1) UA113522C2 (ru)
WO (1) WO2013028177A1 (ru)
ZA (1) ZA201401027B (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102111346B1 (ko) 2019-08-20 2020-05-22 아영창 침전으로부터 안정한 소듐디옥시콜레이트를 포함하는 수용액상 조성물

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
JP2018532806A (ja) * 2015-11-04 2018-11-08 キセラ バイオファーマシューティカルズ インコーポレイテッド デオキシコール酸およびその塩による蓄積脂肪の処置方法
KR101841193B1 (ko) * 2016-09-22 2018-03-22 이경락 저장성 지방 분해 조성물 및 그의 제조 방법
US20180078621A1 (en) * 2016-09-22 2018-03-22 Kyoung Lack Lee Composition for hypotonic lipolysis and manufacturing method thereof
US20190314388A1 (en) * 2018-04-16 2019-10-17 Penmix Ltd. Pharmaceutical composition containing deoxycholic acid
KR102172439B1 (ko) * 2018-12-05 2020-10-30 송미희 지방 분해용 조성물 및 이를 포함하는 주사제 조성물
KR102064864B1 (ko) 2019-02-08 2020-01-10 (주)제테마 국소 주사용 조성물
KR20220026068A (ko) 2020-08-25 2022-03-04 강명범 지방 분해용 주사제 조성물
CN116617160A (zh) * 2023-07-25 2023-08-22 山东则正医药技术有限公司 水性混悬液及制备方法、冻干粉及应用、脂肪消减注射剂

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417179B1 (en) 1998-10-13 2002-07-09 Craig G. Burkhart Ear wax solution

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2754709B1 (fr) 1996-10-23 1999-03-05 Sanofi Sa Composition cosmetique contenant un antagoniste des recepteurs du neuropeptide gamma et alpha 2 antagonistes susceptibles d'etre incorpores dans une telle composition
RU2224523C2 (ru) * 1998-07-24 2004-02-27 Сео Хонг Ю Водный раствор, содержащий желчную кислоту, и способ его получения
US20050048126A1 (en) * 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
DE10361067A1 (de) * 2003-12-22 2005-07-14 Aventis Pharma Deutschland Gmbh Medikamentöse Lipolyse von Fettansammlungen
US20060127468A1 (en) 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
EP2422789B1 (en) 2004-05-19 2017-11-22 Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center Injectable coposition comprising sodium deoxycholate
US7754230B2 (en) 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
EP1888101B1 (en) 2005-06-06 2012-03-21 Georgetown University Compositions and methods for lipo modeling
TW201011755A (en) 2008-09-10 2010-03-16 Skymedi Corp Flash memory system and its data recovery method
JP5420946B2 (ja) * 2009-03-23 2014-02-19 富士フイルム株式会社 胆汁酸を含むミノキシジル水性組成物
EP2645099A1 (en) 2012-03-30 2013-10-02 Phares Pharmaceutical Research N.V. Biorelevant compositions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417179B1 (en) 1998-10-13 2002-07-09 Craig G. Burkhart Ear wax solution

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Dermatologic Surgery, 2009, 35, 792-803.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102111346B1 (ko) 2019-08-20 2020-05-22 아영창 침전으로부터 안정한 소듐디옥시콜레이트를 포함하는 수용액상 조성물

Also Published As

Publication number Publication date
SG2014013205A (en) 2014-05-29
KR102034606B1 (ko) 2019-10-22
AU2018202807B2 (en) 2020-01-16
EA029305B1 (ru) 2018-03-30
AU2011375432B2 (en) 2016-02-04
CN108619089A (zh) 2018-10-09
KR20170075016A (ko) 2017-06-30
KR20190119677A (ko) 2019-10-22
CN103826608A (zh) 2014-05-28
CR20140053A (es) 2014-06-12
IN2014CN02188A (ru) 2015-05-29
KR20200013103A (ko) 2020-02-05
JP5919597B2 (ja) 2016-05-18
KR102073536B1 (ko) 2020-02-04
MX2014001495A (es) 2014-04-25
KR20150000448A (ko) 2015-01-02
MY184277A (en) 2021-03-30
CA2842177C (en) 2016-07-19
IL230547A0 (en) 2014-03-31
KR20180123734A (ko) 2018-11-19
AU2011375432A1 (en) 2014-02-06
CN108743522A (zh) 2018-11-06
AU2018202807A1 (en) 2018-05-10
JP2014524467A (ja) 2014-09-22
EA201490175A1 (ru) 2014-06-30
AU2016202661A1 (en) 2016-05-19
NZ620040A (en) 2016-06-24
ZA201401027B (en) 2017-09-27
PH12016501175B1 (en) 2017-12-11
CA2842177A1 (en) 2013-02-28
BR112014000547B1 (pt) 2021-11-09
BR112014000547A2 (pt) 2017-02-14
UA113522C2 (xx) 2017-02-10
WO2013028177A1 (en) 2013-02-28
AU2016202661B2 (en) 2018-02-22
IL230547A (en) 2017-02-28
PH12016501175A1 (en) 2017-12-11
MX350390B (es) 2017-09-06
KR101751585B1 (ko) 2017-06-27

Similar Documents

Publication Publication Date Title
US20210252021A1 (en) Formulations of deoxycholic acid and salts thereof
KR101919269B1 (ko) 데옥시콜린산 및 그의 염들의 제형물들
US20220072011A1 (en) Treatments of accumulated fat with deoxycholic acid and salts thereof
EP3305298B1 (en) Formulations of deoxycholic acid and salts thereof
JP6219430B2 (ja) デオキシコール酸およびその塩類の製剤
JP6594486B2 (ja) デオキシコール酸およびその塩類の製剤
JP6356329B2 (ja) デオキシコール酸およびその塩類の製剤
EA034320B1 (ru) Композиции дезоксихолата натрия

Legal Events

Date Code Title Description
A107 Divisional application of patent
A201 Request for examination
E902 Notification of reason for refusal
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
J206 Request for trial to confirm the scope of a patent right
J301 Trial decision

Free format text: TRIAL NUMBER: 2020100000862; TRIAL DECISION FOR CONFIRMATION OF THE SCOPE OF RIGHT_DEFENSIVE REQUESTED 20200317

Effective date: 20201020

J206 Request for trial to confirm the scope of a patent right
J301 Trial decision

Free format text: TRIAL NUMBER: 2021100001476; TRIAL DECISION FOR CONFIRMATION OF THE SCOPE OF RIGHT_DEFENSIVE REQUESTED 20210518

Effective date: 20211026