KR101894600B1 - 비-지질 외피 바이러스의 증가된 제거를 위한 ｖｗｆ의 정제 - Google Patents

비-지질 외피 바이러스의 증가된 제거를 위한 ｖｗｆ의 정제 Download PDF

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KR101894600B1
KR101894600B1 KR1020127005935A KR20127005935A KR101894600B1 KR 101894600 B1 KR101894600 B1 KR 101894600B1 KR 1020127005935 A KR1020127005935 A KR 1020127005935A KR 20127005935 A KR20127005935 A KR 20127005935A KR 101894600 B1 KR101894600 B1 KR 101894600B1
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gly
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KR20120065342A (ko
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아르투르 미테러
마인하르트 하슬라허
크리스타 마이어
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박스알타 인코퍼레이티드
박스앨타 게엠베하
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Assigned to 다케다 야쿠힌 고교 가부시키가이샤 reassignment 다케다 야쿠힌 고교 가부시키가이샤 권리의 전부이전등록 Assignors: 박스알타 인코퍼레이티드, 박스앨타 게엠베하
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020127005935A 2009-08-20 2010-08-20 비-지질 외피 바이러스의 증가된 제거를 위한 ｖｗｆ의 정제 Active KR101894600B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23557009P 2009-08-20 2009-08-20
US61/235,570 2009-08-20
PCT/US2010/046180 WO2011022657A1 (en) 2009-08-20 2010-08-20 Purification of vwf for increased removal of non-lipid enveloped viruses

Publications (2)

Publication Number Publication Date
KR20120065342A KR20120065342A (ko) 2012-06-20
KR101894600B1 true KR101894600B1 (ko) 2018-09-03

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ID=43063204

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KR1020127005935A Active KR101894600B1 (ko) 2009-08-20 2010-08-20 비-지질 외피 바이러스의 증가된 제거를 위한 ｖｗｆ의 정제

Country Status (18)

Country Link
US (1) US9315560B2 (cg-RX-API-DMAC10.html)
EP (1) EP2467399B2 (cg-RX-API-DMAC10.html)
JP (1) JP5838159B2 (cg-RX-API-DMAC10.html)
KR (1) KR101894600B1 (cg-RX-API-DMAC10.html)
CN (2) CN106008697B (cg-RX-API-DMAC10.html)
AU (1) AU2010284116B9 (cg-RX-API-DMAC10.html)
BR (1) BR112012003802B1 (cg-RX-API-DMAC10.html)
CA (1) CA2771232A1 (cg-RX-API-DMAC10.html)
DK (1) DK2467399T3 (cg-RX-API-DMAC10.html)
ES (1) ES2562256T5 (cg-RX-API-DMAC10.html)
HU (1) HUE026907T2 (cg-RX-API-DMAC10.html)
IN (1) IN2012DN01849A (cg-RX-API-DMAC10.html)
MX (1) MX2012002129A (cg-RX-API-DMAC10.html)
NZ (1) NZ598249A (cg-RX-API-DMAC10.html)
PL (1) PL2467399T3 (cg-RX-API-DMAC10.html)
PT (1) PT2467399E (cg-RX-API-DMAC10.html)
SG (2) SG178478A1 (cg-RX-API-DMAC10.html)
WO (1) WO2011022657A1 (cg-RX-API-DMAC10.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11197916B2 (en) 2007-12-28 2021-12-14 Takeda Pharmaceutical Company Limited Lyophilized recombinant VWF formulations
EP2349314B1 (en) 2008-10-21 2013-02-27 Baxter International Inc. Lyophilized recombinant vwf formulations
WO2013192009A1 (en) * 2012-06-21 2013-12-27 Baxter International Inc. Virus filtration of cell culture media
JP6320429B2 (ja) * 2013-02-22 2018-05-09 エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ 負帯電粒子を用いるウイルス調製物のクロマトグラフィー精製
BR112016026842A2 (pt) * 2014-06-06 2017-12-12 Octapharma Ag preparação compreendendo fator viii e peptídeos de fator de von willebrand
EP3158055B1 (en) 2014-06-13 2019-09-11 CSL Limited Improved production of recombinant von willebrand factor in a bioreactor
EP3672644A1 (en) 2017-08-23 2020-07-01 CSL Behring GmbH Method for virus filtration of von willebrand factor
CA3094644A1 (en) 2018-03-21 2019-09-26 Baxalta Incorporated Separation of vwf and vwf propeptide by chromatographic methods
EP4490042A4 (en) 2022-03-08 2026-03-04 Equashield Medical Ltd FLUID TRANSFER STATION IN A ROBOTIC PHARMACEUTICAL PREPARATION SYSTEM

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465624B1 (en) 1997-02-27 2002-10-15 Baxter Aktiengesellschaft Purification of von-Willebrand factor by cation exchanger chromatography

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3941763A (en) 1975-03-28 1976-03-02 American Home Products Corporation PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates
WO1986006096A1 (en) 1985-04-11 1986-10-23 The Children's Medical Center Corporation Von willebrand factor
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
AT406373B (de) * 1997-02-27 2000-04-25 Immuno Ag Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie
AT405485B (de) 1997-05-28 1999-08-25 Immuno Ag Eine das vwf-propeptid enthaltende pharmazeutische präparation
US6531577B1 (en) 1997-12-15 2003-03-11 Hemasure Denmark A/S von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations
ATE370961T1 (de) * 1998-05-06 2007-09-15 Genentech Inc Reinigung von antikörpern durch ionenaustauschchromatographie
AU2005322067B8 (en) 2004-12-27 2012-07-26 Takeda Pharmaceutical Company Limited Polymer-von Willebrand factor-conjugates

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465624B1 (en) 1997-02-27 2002-10-15 Baxter Aktiengesellschaft Purification of von-Willebrand factor by cation exchanger chromatography

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Biologicals.,25(4): pp.391-401, 1997.
Thromb Res., 1;105(5), pp.391-400, 2002.
Transfusion and Apheresis Science, 39(1), pp. 75-82, 2008.

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Publication number Publication date
JP5838159B2 (ja) 2015-12-24
BR112012003802B1 (pt) 2022-10-25
MX2012002129A (es) 2012-06-08
PT2467399E (pt) 2016-03-18
EP2467399B1 (en) 2015-11-11
ES2562256T5 (es) 2023-07-20
CN106008697A (zh) 2016-10-12
JP2013502434A (ja) 2013-01-24
US20110092681A1 (en) 2011-04-21
BR112012003802A2 (pt) 2016-11-22
EP2467399B2 (en) 2023-02-01
AU2010284116B9 (en) 2015-03-26
KR20120065342A (ko) 2012-06-20
AU2010284116B2 (en) 2015-02-12
HUE026907T2 (en) 2016-07-28
PL2467399T3 (pl) 2016-05-31
US9315560B2 (en) 2016-04-19
DK2467399T3 (en) 2017-01-23
WO2011022657A1 (en) 2011-02-24
NZ598249A (en) 2014-04-30
CA2771232A1 (en) 2011-02-24
CN106008697B (zh) 2020-08-04
ES2562256T3 (es) 2016-03-03
CN102482341A (zh) 2012-05-30
AU2010284116A1 (en) 2012-03-08
IN2012DN01849A (cg-RX-API-DMAC10.html) 2015-08-21
SG178478A1 (en) 2012-04-27
SG10201408106WA (en) 2015-01-29
EP2467399A1 (en) 2012-06-27

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