KR101804130B1 - Gel pad for ultrasonic wave - Google Patents

Abstract

The present invention relates to a gel pad for ultrasonic waves, and more particularly, to a gel pad for ultrasonic waves with excellent definition, tensile strength, and compressive strength by using a composite gelling agent composed of carrageenan, ceratonia siliqua gum, potassium chloride, and cellulose gum.

Description

Gel pad for ultrasonic wave}

The present invention relates to a gel pad for ultrasonic waves, and more particularly, to a gel pad for ultrasonic waves, which is excellent in sharpness, tensile strength and compressive strength by using a composite gelling agent composed of carrageenan, seratonia siliqua gum, potassium chloride and cellulose gum And a gel pad for ultrasonic waves.

Ultrasound is a sound wave with a frequency of about 20,000 Hz that can not be perceived as sound by the human ear, and is essentially the same in nature as the sound wave in the audible range. However, since the frequency is high and therefore the wavelength is short, a considerably strong vibration is generated, so that it can not be seen by ordinary sound waves. For example, the path is directional and a short pulse is generated. Utilizing the properties of these ultrasonic waves, in the medical field, ultrasound is used to obtain images of the internal structure of the human body. Ultrasonography is a technique that radiates high-frequency (3MHz to 25MHz) sound waves to the human body and graphically reflects the signals reflected from each organs. It is used to diagnose the condition of the fetus in the obstetrics and gynecology Is widely used to diagnose the condition, and is widely used in ultrasonic physical therapy in rehabilitation treatment. In such an ultrasonic examination and treatment, when the ultrasonic waves are propagated inside the human body, a medium called interphase is required to prevent the sound waves from scattering into the air. That is, an intermediate layer is required as an ultrasonic transmission medium in order to propagate the ultrasonic waves to the inside of the human body and spread the ultrasonic waves evenly, so that the reflected ultrasonic signals reach the receiver completely. This intermediate layer is usually a product in gel form.

However, such gel-like products are not suitable for visualization of images of organs in the apparent bend or near field. That is, when a gel-like product is used as an intermediate layer in an ultrasonic inspection for obtaining a structure of an organ in an apparent bend or a near field, the resolution and sharpness of the image are degraded. On the other hand, a near field is also called a near field and is a region very close to a sound source, generally a distance range smaller than the wavelength of the lowest frequency emitted from the sound source.

In order to solve this problem, Korean Patent Registration No. 10-0511341 discloses a process for preparing an aqueous solution by adding 0.1 to 10% by weight of carrageenan, 0 to 10% by weight of a polyhydric alcohol and 0.005 to 0.6% by weight of a preservative in water, Step 1); (2) a step of pouring the aqueous solution of step (1) into a tray and molding it into a gel by maintaining the aqueous solution temperature at 10 to 40 DEG C; and (3) packaging the sheet of step (2) .

However, the registered patent uses only carrageenan as a gelling agent, which has a problem that the sharpness of the ultrasonic image is low and it tears easily.

Disclosure of Invention Technical Problem [8] Accordingly, the present invention has been made keeping in mind the above problems occurring in the prior art, and it is an object of the present invention to provide a composite gelling agent composed of carrageenan, ceratonia siliqua gum, potassium chloride and cellulose gum, And to provide an ultrasonic wave gel pad excellent in sharpness, tensile strength and compressive strength.

The problems to be solved by the present invention are not limited to those mentioned above, and other solutions not mentioned can be clearly understood by those skilled in the art from the following description.

In order to attain the above object, the present invention provides a gel pad for ultrasonic waves comprising polyhydric alcohols, a gelling agent, and a preservative, wherein the gelling agent is selected from the group consisting of carrageenan, ceratonia, siliqua gum), potassium chloride, and cellulose gum.

In addition, in the ultrasonic wave gel pad according to the present invention, the composite gelling agent may include 2.5 to 3.5% by weight of carrageenan, 1 to 1.5% by weight of ceratonia siliqua gum, 0.05 to 5% by weight of potassium chloride, 0.1% by weight, and cellulose gum at 0.01 to 0.1% by weight.

In addition, in the ultrasonic wave gel pad according to the present invention, the preservative is characterized by containing 0.2 to 0.4% by weight of chlorphenesin and 0.4 to 1.0% by weight of phenoxy ethanol.

The gel pad for ultrasonic waves according to the present invention may further comprise 0.005 to 0.01% by weight of PPG-Buteths, 0.005 to 0.01% of PEG-40 Hydrogenated castor oil, % ≪ / RTI > by weight.

Further, the ultrasonic wave gel pad according to the present invention is characterized by further containing 0.3 to 0.5% by weight of sucrose.

The ultrasonic wave gel pad according to the present invention having the above-described structure can be used as a composite gellant composed of carrageenan, ceratonia siliqua gum, potassium chloride and cellulose gum, And excellent tensile strength and compressive strength.

The effects of the present invention are not limited to those mentioned above, and other solutions not mentioned may be clearly understood by those skilled in the art from the following description.

1 is a photograph of a circular gel pad of Example 1. Fig.
Fig. 2 is a photograph of the circular gel pad of Comparative Example 1. Fig.
3 is a photograph of a process of measuring sharpness.
4A to 4C show ultrasonic photographs of Examples 1 and 2 and Comparative Example 1, respectively.
FIG. 5 is a photograph of a sample taken from the Korea Atomic Energy Research Institute.

Preferred embodiments of the present invention will be described in detail.

In the following description of the present invention, a detailed description of known functions and configurations incorporated herein will be omitted when it may make the subject matter of the present invention rather unclear. In addition, the terms described below are defined in consideration of the functions of the present invention, and these may vary depending on the intention of the user, the operator, or the precedent. Therefore, the definition should be based on the contents throughout this specification.

The gel pad for ultrasonic waves according to the present invention is intended to improve the sharpness, elasticity and strength of images which are disadvantages of Korean Patent No. 10-0511341 which uses carrageenan as a gelling agent. The gel pad is composed of a polyhydric alcohol, a complex gelling agent, Of purified water.

Here, the polyhydric alcohol may be a polyol such as ethylene glycol, propylene glycol, 1,3-butylene glycol, hexylene glycol, glycerin, polyethylene glycol, polypropylene glycol, sorbitol, mannitol, Can be used.

The composite gelling agent is characterized by comprising carrageenan, ceratonia siliqua gum, potassium chloride, and cellulose gum.

In the case of using the carrageenan alone as a gelling agent, in order to solve the problem that the tensile strength and the compressive strength are easily weakened in the course of use in the case of the above-mentioned registered patent, the existing carrageenan Ceratonia siliqua gum , Potassium chloride (potassium chloride) and cellulose gum (cellulose gum).

Ceratonia siliqua gum is obtained by pulverizing the seeds of mature fruit of Ceratonia siliqua, and is used as an adhesive, a binder, an emulsion stabilizer, a fragrance, and an increasing agent in cosmetics.

The above potassium chloride and the cellulose act as a black water-soluble thickener.

More specifically, the composite gelling agent comprises 2.5 to 3.5% by weight of carrageenan, 1 to 1.5% by weight of ceratonia siliqua gum, 0.05 to 0.1% by weight of potassium chloride, 0.01 to 0.1% by weight of cellulose gum To 0.1% by weight.

Experiments have shown that the use of a composite gelling agent having such a composition and composition ratio can be expected to improve not only the tensile strength but also the compressive strength.

The preservative can be exemplified by chlorphenesin and phenoxy ethanol.

The chlorphenesin is 0.2 to 0.4% by weight, and the phenoxy ethanol is 0.4 to 1.0% by weight.

The ultrasonic gel pads of the present invention may contain 0.005 to 0.01% by weight of polypropylene glycol butes, 0.005 to 0.01% by weight of PEG-40 hydro genated castor oil, And 0.3 to 0.5% by weight of sucrose.

Examples of the polypropylene glycol butes include PPG-12-Buteth-16, PPG-9-Buteth-12, PPG-26-Buteth-26 and PPG-28-Buteth-35.

The PEG-40 Hydrogenated castor oil serves as a surfactant or emulsifier.

The sucrose serves as a wetting agent.

Hereinafter, a method of manufacturing an ultrasonic wave gel pad according to the present invention will be described.

The method for manufacturing an ultrasonic wave gel pad according to the present invention can be roughly divided into a raw material mixing step, a coating and cooling step, and a molding step.

In the raw material mixing step, the above-mentioned polyhydric alcohol, gelling agent, preservative and the like and purified water are placed in a tank, heated at 90 ° C., stirred for 10 to 30 minutes, and then defoamed and filtered to prepare a semi-finished product .

In the coating and cooling step, the semi-finished product is coated between a pair of films and then cooled. Here, the pair of films may be a glossy film at the bottom and a PET film at the top. More specifically, the semi-finished product is coated on the lower transparent pearl film, the semi-finished product is covered with the upper PET film, and then the semi-finished product is cooled to gel to prepare a gel pad.

In the forming step, the gel pad is punched to be formed into a predetermined size and shape.

Hereinafter, a more preferred embodiment of the ultrasonic wave gel pad according to the present invention will be described.

, 73.118% by weight of purified water, 22% by weight of glycerin, 3% by weight of condrus cripus pewder (carrageenan), 1.2% by weight of Ceratonia siliqua gum, 0.051% by weight of potassium chloride, A raw material composition composed of 0.021% by weight of gum, 0.2% by weight of chlorphenesin and 0.41% by weight of phenoxy ethanol is prepared.

The raw material composition is placed in a tank, stirred for 10 minutes while heating at 90 DEG C, and subjected to defoaming and filtration to prepare a semi-finished product.

The prepared semi-finished product is poured into a tray and cooled at room temperature to form a circular gel pad (see Fig. 1) having a diameter of 9 cm and a thickness of 4 mm and a rectangular gel pad having a thickness of 2 mm x 10 mm width x 6 mm length.

, 72.714% by weight of purified water, 22% by weight of glycerin, 3% by weight of condrus cripus pewder (carrageenan), 1.2% by weight of Ceratonia siliqua gum, 0.051% by weight of potassium chloride, 0.2% by weight of gum, 0.2% by weight of chlorphenesin, 0.41% by weight of phenoxy ethanol, 0.05% by weight of disodium EDTA, 0.005% by weight of PPG-26-Buteth- 0.005% by weight of a PEG-40 Hydrogenated castor oil and 0.344% by weight of sucrose are prepared.

The raw material composition is placed in a tank, stirred for 10 minutes while heating at 90 DEG C, and subjected to defoaming and filtration to prepare a semi-finished product.

The prepared semi-finished product is poured into a tray and cooled at room temperature to prepare a circular gel pad having a diameter of 9 cm and a thickness of 4 mm and a rectangular gel pad having a thickness of 2 mm x 10 mm width x 6 mm length.

[ Comparative Example 1 ]

A raw material composition composed of purified water in an amount of 95.95 wt% of purified water, 3 wt% of carrageenan, 0.05 wt% of bronopol, and 1 wt% of polyethylene glycol (PEG) was prepared as in the composition disclosed in Korean Patent No. 10-0511341, Add to the tank and stir for 10 minutes while heating at 90 ° C, then defoamed and filtered to provide semi-finished products.

The prepared semi-finished product is poured into a tray and cooled at room temperature to form a circular gel pad (see Fig. 2) having a diameter of 9 cm and a thickness of 4 mm and a rectangular gel pad having a thickness of 2 mm, a width of 10 mm and a length of 6 mm.

[Experimental Example 1] Measurement of sharpness

The circular gel pads (A) of Examples 1 and 2 and Comparative Example 1 were placed on a US CIRS Phantom Model 054 ultrasonic measuring instrument as shown in FIG. 3, and an ultrasonic photograph was taken while rubbing with an ultrasonic measuring probe (B) (C) as in the ultrasonic photograph of Fig. 4 (b).

As can be seen from the photographs of FIGS. 4A to 4C, the sharpness was excellent in Example 2 (FIG. 4B), followed by Example 1 (FIG. 4A) C) could not be confirmed.

[Experimental Example 2] Measurement of tensile strength

The tensile strength of the gel pads of Examples 1 and 2 and Comparative Example 1 was measured using INSTRON Series IX (Instron Co., Universal Testing System Model 4400). The cross head speed was 15 mm / min and the span length was 40 mm. The results are shown in Table 1 below.

[Experimental Example 3] Measurement of compressive strength

The compressive strength of the gel pads of Examples 1 and 2 and Comparative Example 1 was measured using INSTRON Series IX (Instron Co., Universal Testing System Model 4400). The cross head speed was 10 mm / min for the compressive strength measurement, and the value when the gel pad was 10% deformed was measured. The results are shown in Table 1 below.

Example 1 Example 2 Comparative Example 1 Tensile strength (kgf / cm2) 2.65 2.81 0.37 Compressive strength (kgf / ㎠) 0.51 0.59 0.12

Referring to Table 1, it was confirmed that the gel pads of Examples 1 and 2 of the present invention had significantly higher tensile strength and compressive strength than the gel pads of Comparative Example 1. [

On the other hand, the circular gel pad of Example 1 shown in Fig. 1 had lower transparency when viewed from the naked eye than that of the circular gel pad of Fig. 2 in which only carrageenan was added as a gelling agent. However, as shown in Experimental Examples 1 to 3, , Excellent sharpness, excellent tensile strength and compressive strength.

On the other hand, referring to FIG. 5, it was confirmed that the gel pad using only carrageenan as a gelling agent had a weak strength such as tearing even if it was caught with a finger.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, is intended to cover various modifications and equivalent arrangements included within the spirit and scope of the invention. Therefore, it is to be understood that the present invention is not limited to the above-described embodiments. Accordingly, the true scope of the present invention should be determined by the technical idea of the appended claims. It is also to be understood that the invention includes all modifications, equivalents, and alternatives falling within the spirit and scope of the invention as defined by the appended claims.

Claims (5)

In a gel pad for ultrasonic waves comprising a polyhydric alcohol, a gelling agent and a preservative,
The gelling agent is a composite gelling agent composed of carrageenan, Ceratonia siliqua gum, potassium chloride, and cellulose gum,
Wherein the composite gelling agent comprises 2.5 to 3.5% by weight of carrageenan, 1 to 1.5% by weight of ceratonia siliqua gum, 0.05 to 0.1% by weight of potassium chloride, %, And cellulose sulphate 0.01 to 0.1% by weight,
The antiseptic agent is composed of 0.2 to 0.4% by weight of chlorphenesin and 0.4 to 1.0% by weight of phenoxy ethanol based on the total weight of the ultrasonic wave gel pad,
0.005 to 0.01% by weight of polypropylene glycol butes and 0.005 to 0.01% by weight of PEG-40 hydrogenated castor oil, based on the total weight of the gel pads for ultrasonic waves, And 0.3 to 0.5% by weight of sucrose, based on the total weight of the gel pads.
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