KR101755133B1 - 이미노슈가 및 바이러스성 질환을 치료하는 방법 - Google Patents

이미노슈가 및 바이러스성 질환을 치료하는 방법 Download PDF

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KR101755133B1
KR101755133B1 KR1020157006783A KR20157006783A KR101755133B1 KR 101755133 B1 KR101755133 B1 KR 101755133B1 KR 1020157006783 A KR1020157006783 A KR 1020157006783A KR 20157006783 A KR20157006783 A KR 20157006783A KR 101755133 B1 KR101755133 B1 KR 101755133B1
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dnj
cells
virus
dengue
substituted
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KR20150038684A (ko
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얼반 람스테트
브렌난 클로세
니콜 지츠만
레이몬드 에이. 드웩
테리 디. 버터스
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유나이티드 세러퓨틱스 코오포레이션
더 챈슬러 마스터즈 앤드 스칼라스 오브 더 유니버시티 오브 옥스포드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
KR1020157006783A 2009-02-23 2010-02-22 이미노슈가 및 바이러스성 질환을 치료하는 방법 Expired - Fee Related KR101755133B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US20236709P 2009-02-23 2009-02-23
US61/202,367 2009-02-23
US27225509P 2009-09-04 2009-09-04
US61/272,255 2009-09-04
PCT/US2010/024920 WO2010096764A1 (en) 2009-02-23 2010-02-22 Iminosugars and methods of treating viral diseases

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KR1020117021770A Division KR20120042716A (ko) 2009-02-23 2010-02-22 이미노슈가 및 바이러스성 질환을 치료하는 방법

Publications (2)

Publication Number Publication Date
KR20150038684A KR20150038684A (ko) 2015-04-08
KR101755133B1 true KR101755133B1 (ko) 2017-07-06

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KR1020117021770A Ceased KR20120042716A (ko) 2009-02-23 2010-02-22 이미노슈가 및 바이러스성 질환을 치료하는 방법

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US (4) US8450345B2 (https=)
EP (1) EP2398321B1 (https=)
JP (3) JP5600329B2 (https=)
KR (2) KR101755133B1 (https=)
CN (2) CN106420740A (https=)
CA (1) CA2753195C (https=)
ES (1) ES2579628T3 (https=)
WO (1) WO2010096764A1 (https=)

Families Citing this family (8)

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KR20150035767A (ko) 2012-06-06 2015-04-07 유니터 바이롤로지, 엘엘씨 신규 이미노당 및 그의 용도
JP2016513729A (ja) * 2013-03-15 2016-05-16 ユニザー ヴィロロジー，エルエルシー 抗菌化合物
JP6456393B2 (ja) 2013-09-16 2019-01-23 エマージェント バイロロジー エルエルシー デオキシノジリマイシン誘導体およびその使用方法
BR112017008898B1 (pt) 2014-11-05 2022-11-29 Emergent Virology Llc Compostos de iminoaçúcares, suas composições farmacêuticas e usos dos mesmos para tratar doenças virais
WO2017201052A1 (en) * 2016-05-16 2017-11-23 Emergent Virology Llc Methods of treating zika virus infection
KR101942757B1 (ko) 2017-08-23 2019-01-28 주식회사 유앤아이미트 마이크로웨이브를 이용한 n-노닐데옥시노지리마이신의 제조방법
CN113425720A (zh) * 2020-04-03 2021-09-24 深圳前海诺贝尔奖科学家技术转移转化有限公司 亚胺糖化合物在制备抗SARS-CoV-2病毒的药物中的用途
CN119841765B (zh) * 2025-01-09 2025-10-10 中南大学 Dnj衍生物、药物组合物及其应用

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KR20120042716A (ko) 2012-05-03
CA2753195C (en) 2015-06-02
US9943532B2 (en) 2018-04-17
WO2010096764A1 (en) 2010-08-26
US9044470B2 (en) 2015-06-02
CN102655746A (zh) 2012-09-05
JP2014237706A (ja) 2014-12-18
JP2016175937A (ja) 2016-10-06
JP5940607B2 (ja) 2016-06-29
HK1165221A1 (zh) 2012-10-05
CN106420740A (zh) 2017-02-22
US20170304333A1 (en) 2017-10-26
US9579334B2 (en) 2017-02-28
US20130237567A1 (en) 2013-09-12
ES2579628T3 (es) 2016-08-12
US20150224128A1 (en) 2015-08-13
US8450345B2 (en) 2013-05-28
JP5600329B2 (ja) 2014-10-01
EP2398321A4 (en) 2012-01-04
EP2398321B1 (en) 2015-11-25
EP2398321A1 (en) 2011-12-28
US20100222383A1 (en) 2010-09-02
CN102655746B (zh) 2016-08-03
KR20150038684A (ko) 2015-04-08
JP2012518649A (ja) 2012-08-16
CA2753195A1 (en) 2010-08-26

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