KR101707580B1 - 선택적 11-베타-하이드록시스테로이드 디하이드로게나제 타입 1 억제제로서 융합된 피롤리디노-사이클로프로판 유도체들 - Google Patents

선택적 11-베타-하이드록시스테로이드 디하이드로게나제 타입 1 억제제로서 융합된 피롤리디노-사이클로프로판 유도체들 Download PDF

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KR101707580B1
KR101707580B1 KR1020117007670A KR20117007670A KR101707580B1 KR 101707580 B1 KR101707580 B1 KR 101707580B1 KR 1020117007670 A KR1020117007670 A KR 1020117007670A KR 20117007670 A KR20117007670 A KR 20117007670A KR 101707580 B1 KR101707580 B1 KR 101707580B1
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KR20110059749A (ko
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에릭 발뢰르
프랑크 레피프레
디디에 로쉐
데니스 카르니아토
세르쥬 크리스티만-프랑크
파비엥 슈미들린
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메르크 파텐트 게엠베하
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KR1020117007670A 2008-09-01 2009-08-05 선택적 11-베타-하이드록시스테로이드 디하이드로게나제 타입 1 억제제로서 융합된 피롤리디노-사이클로프로판 유도체들 Expired - Fee Related KR101707580B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08290822.9 2008-09-01
EP08290822 2008-09-01
PCT/EP2009/005654 WO2010022850A1 (en) 2008-09-01 2009-08-05 Fused pyrrolidino-cyclopropane derivatives as selective 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors

Publications (2)

Publication Number Publication Date
KR20110059749A KR20110059749A (ko) 2011-06-03
KR101707580B1 true KR101707580B1 (ko) 2017-02-16

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KR1020117007670A Expired - Fee Related KR101707580B1 (ko) 2008-09-01 2009-08-05 선택적 11-베타-하이드록시스테로이드 디하이드로게나제 타입 1 억제제로서 융합된 피롤리디노-사이클로프로판 유도체들

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US (1) US8486964B2 (enExample)
EP (1) EP2321317B1 (enExample)
JP (1) JP5579717B2 (enExample)
KR (1) KR101707580B1 (enExample)
CN (1) CN102137864B (enExample)
AR (1) AR073224A1 (enExample)
AU (1) AU2009287118B9 (enExample)
BR (1) BRPI0918288B1 (enExample)
CA (1) CA2735286C (enExample)
EA (1) EA020238B1 (enExample)
ES (1) ES2531633T3 (enExample)
IL (1) IL211447A (enExample)
MX (1) MX2011002181A (enExample)
WO (1) WO2010022850A1 (enExample)
ZA (1) ZA201102418B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9580422B2 (en) * 2013-10-22 2017-02-28 Bristol-Myers Squibb Company Isotopically labeled triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
MA40759A (fr) 2014-09-26 2017-08-01 Pfizer Modulateurs de rorc2 de type pyrrolopyridine substitué par un méthyle et trifluorométhyle et leurs procédés d'utilisation
EP3235813A1 (en) 2016-04-19 2017-10-25 Cidqo 2012, S.L. Aza-tetra-cyclo derivatives
CA3243547A1 (en) * 2021-12-21 2023-06-29 Corcept Therapeutics Inc INDAZOLE GLUCOCORTICOID RECEPTOR BICYCLIC ANTAGONISTS

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4088652A (en) 1975-07-31 1978-05-09 American Cyanamid Company Acylazabicyclohexanes
WO2004089896A1 (en) 2003-04-11 2004-10-21 Novo Nordisk A/S 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ACTIVE COMPOUNDS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003287909A1 (en) * 2003-01-08 2004-08-10 Mibitech Aps Electro-therapeutic device and method of electro-therapeutic treatment
US7700583B2 (en) 2003-04-11 2010-04-20 High Point Pharmaceuticals, Llc 11β-hydroxysteroid dehydrogenase type 1 active compounds
WO2006106423A2 (en) * 2005-04-07 2006-10-12 Pfizer Inc. Amino sulfonyl derivatives as inhibitors of human 11-.beta.-hydrosysteroid dehydrogenase
EP1971614A1 (en) * 2005-11-14 2008-09-24 Probiodrug AG Cyclopropyl-fused pyrrolidine derivatives as dipeptidyl peptidase iv inhibitors
GB0625198D0 (en) 2006-12-18 2007-01-24 Glaxo Group Ltd Chemical compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4088652A (en) 1975-07-31 1978-05-09 American Cyanamid Company Acylazabicyclohexanes
WO2004089896A1 (en) 2003-04-11 2004-10-21 Novo Nordisk A/S 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ACTIVE COMPOUNDS

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ES2531633T3 (es) 2015-03-18
EA020238B1 (ru) 2014-09-30
BRPI0918288A2 (pt) 2015-12-22
EP2321317A1 (en) 2011-05-18
CN102137864B (zh) 2014-12-31
BRPI0918288B1 (pt) 2018-11-06
AU2009287118B2 (en) 2014-02-27
EA201100419A1 (ru) 2011-10-31
US20110172265A1 (en) 2011-07-14
JP2012501302A (ja) 2012-01-19
CA2735286A1 (en) 2010-03-04
AU2009287118A1 (en) 2010-03-04
IL211447A (en) 2014-07-31
US8486964B2 (en) 2013-07-16
CN102137864A (zh) 2011-07-27
WO2010022850A1 (en) 2010-03-04
MX2011002181A (es) 2011-03-30
IL211447A0 (en) 2011-05-31
JP5579717B2 (ja) 2014-08-27
EP2321317B1 (en) 2014-12-24
AU2009287118B9 (en) 2014-08-07
CA2735286C (en) 2017-12-05
AR073224A1 (es) 2010-10-20
KR20110059749A (ko) 2011-06-03
ZA201102418B (en) 2011-12-28

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