KR101661825B1 - Src 상동성-2 함유 단백질 티로신 포스파타제-1의 작용물질 및 그를 사용한 치료방법 - Google Patents
Src 상동성-2 함유 단백질 티로신 포스파타제-1의 작용물질 및 그를 사용한 치료방법 Download PDFInfo
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- KR101661825B1 KR101661825B1 KR1020147003923A KR20147003923A KR101661825B1 KR 101661825 B1 KR101661825 B1 KR 101661825B1 KR 1020147003923 A KR1020147003923 A KR 1020147003923A KR 20147003923 A KR20147003923 A KR 20147003923A KR 101661825 B1 KR101661825 B1 KR 101661825B1
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- C07D215/20—Oxygen atoms
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- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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| WO2014032755A2 (en) * | 2012-08-29 | 2014-03-06 | Merck Patent Gmbh | Ddr2 inhibitors for the treatment of osteoarthritis |
| EP2989466B1 (en) * | 2013-04-25 | 2018-10-31 | CBS Bioscience, Co., Ltd | Analytical method for increasing susceptibility of molecular targeted therapy in hepatocellular carcinoma |
| WO2015051149A1 (en) * | 2013-10-04 | 2015-04-09 | The Trustees Of Columbia University In The City Of New York | Sorafenib analogs and uses thereof |
| TW201718474A (zh) | 2015-08-31 | 2017-06-01 | 東麗股份有限公司 | 尿素衍生物及其用途 |
| CN108026035B (zh) * | 2015-09-02 | 2021-03-30 | 陈昆锋 | 具有蛋白酪氨酸磷酸酶shp-1激动剂活性的化合物 |
| US10519113B2 (en) * | 2016-08-17 | 2019-12-31 | Icahn School Of Medicine At Mount Sinai | Kinase inhibitor compounds, compositions, and methods of treating cancer |
| CN109789116B (zh) * | 2016-09-22 | 2022-02-01 | 陈昆锋 | Sc-43用于改善纤维化的用途 |
| AU2018215447A1 (en) * | 2017-02-03 | 2019-08-08 | The Regents Of The University Of California | Compositions and methods for inhibiting reticulon 4 |
| PT3849534T (pt) | 2018-09-10 | 2025-04-01 | Mirati Therapeutics Inc | Combinação de dasatinib e adagrasib para utilização no tratamento de cancro do pulmão de células não pequenas |
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| CN112084184B (zh) * | 2020-09-15 | 2022-12-16 | 青海省地质测绘地理信息院 | 一种在不同gis平台之间异构数据属性传递的方法 |
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| DE1241832B (de) * | 1963-02-23 | 1967-06-08 | Hoechst Ag | Verfahren zur Herstellung von Pyrimidiniumverbindungen |
| IL89029A (en) * | 1988-01-29 | 1993-01-31 | Lilly Co Eli | Fungicidal quinoline and cinnoline derivatives, compositions containing them, and fungicidal methods of using them |
| WO1993015043A1 (fr) * | 1992-01-24 | 1993-08-05 | Yoshitomi Pharmaceutical Industries, Ltd. | Compose arylalkananilide et utilisation pharmaceutique |
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| BR0013469B1 (pt) * | 1999-08-20 | 2011-01-25 | amidas aromáticas heterocìclicas fungicidas, composição fungicida compreendendo as mesmas, bem como método para o controle ou a prevenção de infestação fúngica. | |
| DE19954312A1 (de) * | 1999-11-11 | 2001-05-17 | Bayer Ag | Substituierte Phenyluracile |
| BR0211810A (pt) * | 2001-08-09 | 2004-08-24 | Ono Pharmaceutical Co | Derivados ácido carboxìlico e agente farmacêutico compreendendo os mesmos como ingrediente ativo |
| WO2005102997A1 (en) * | 2004-04-26 | 2005-11-03 | Astrazeneca Ab | 3,4-disubstituted maleimides for use as vascular damaging agents |
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| US9180127B2 (en) * | 2009-12-29 | 2015-11-10 | Dana-Farber Cancer Institute, Inc. | Type II Raf kinase inhibitors |
| WO2012112570A1 (en) | 2011-02-14 | 2012-08-23 | The Regents Of The University Of California | SORAFENIB DERIVATIVES AS sEH INHIBITORS |
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| European Journal of Medicinal Chemistry, 2011, Vol. 46, pp. 2845-2851 |
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| JP2014527043A (ja) | 2014-10-09 |
| EP2739139A1 (en) | 2014-06-11 |
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| IL230601A (en) | 2017-07-31 |
| CA2843330A1 (en) | 2013-02-07 |
| KR20140039331A (ko) | 2014-04-01 |
| AU2012289961B2 (en) | 2016-05-19 |
| BR112014002363A2 (pt) | 2017-06-13 |
| CN104010501B (zh) | 2016-05-04 |
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| ES2762193T3 (es) | 2020-05-22 |
| PH12014500246A1 (en) | 2014-03-24 |
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| TWI507191B (zh) | 2015-11-11 |
| AU2012289961C1 (en) | 2016-09-01 |
| AU2012289961A1 (en) | 2014-02-20 |
| TW201320997A (zh) | 2013-06-01 |
| CN104010501A (zh) | 2014-08-27 |
| RU2584986C2 (ru) | 2016-05-27 |
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