KR101658347B1 - 폐암 바이오마커 및 그것들의 용도 - Google Patents

폐암 바이오마커 및 그것들의 용도 Download PDF

Info

Publication number
KR101658347B1
KR101658347B1 KR1020117005305A KR20117005305A KR101658347B1 KR 101658347 B1 KR101658347 B1 KR 101658347B1 KR 1020117005305 A KR1020117005305 A KR 1020117005305A KR 20117005305 A KR20117005305 A KR 20117005305A KR 101658347 B1 KR101658347 B1 KR 101658347B1
Authority
KR
South Korea
Prior art keywords
biomarker
biomarkers
lung cancer
individual
rti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020117005305A
Other languages
English (en)
Korean (ko)
Other versions
KR20110063753A (ko
Inventor
래리 골드
마티 스탠튼
에드워드 엔. 브로디
레이첼 엠. 오스트로프
도미닉 지흐
알렉스 에이. 이. 스튜어트
Original Assignee
소마로직, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 소마로직, 인크. filed Critical 소마로직, 인크.
Publication of KR20110063753A publication Critical patent/KR20110063753A/ko
Application granted granted Critical
Publication of KR101658347B1 publication Critical patent/KR101658347B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57423Specifically defined cancers of lung
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10Complex mathematical operations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Data Mining & Analysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Mathematical Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Theoretical Computer Science (AREA)
  • Algebra (AREA)
  • Software Systems (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Databases & Information Systems (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Pure & Applied Mathematics (AREA)
  • Mathematical Optimization (AREA)
  • Mathematical Analysis (AREA)
KR1020117005305A 2008-09-09 2009-09-09 폐암 바이오마커 및 그것들의 용도 Active KR101658347B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US9559308P 2008-09-09 2008-09-09
US61/095,593 2008-09-09
US15283709P 2009-02-16 2009-02-16
US61/152,837 2009-02-16
PCT/US2009/056399 WO2010030697A1 (en) 2008-09-09 2009-09-09 Lung cancer biomarkers and uses thereof

Publications (2)

Publication Number Publication Date
KR20110063753A KR20110063753A (ko) 2011-06-14
KR101658347B1 true KR101658347B1 (ko) 2016-09-21

Family

ID=42005456

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020117005305A Active KR101658347B1 (ko) 2008-09-09 2009-09-09 폐암 바이오마커 및 그것들의 용도

Country Status (14)

Country Link
EP (1) EP2340506B1 (cg-RX-API-DMAC7.html)
JP (1) JP5701212B2 (cg-RX-API-DMAC7.html)
KR (1) KR101658347B1 (cg-RX-API-DMAC7.html)
CN (2) CN102209968B (cg-RX-API-DMAC7.html)
AU (2) AU2009291811B2 (cg-RX-API-DMAC7.html)
CA (3) CA3152591C (cg-RX-API-DMAC7.html)
DK (1) DK2340506T3 (cg-RX-API-DMAC7.html)
ES (1) ES2559758T3 (cg-RX-API-DMAC7.html)
GB (1) GB2478441B (cg-RX-API-DMAC7.html)
HK (1) HK1204062A1 (cg-RX-API-DMAC7.html)
HR (1) HRP20160127T1 (cg-RX-API-DMAC7.html)
MX (1) MX2011002322A (cg-RX-API-DMAC7.html)
SI (1) SI2340506T1 (cg-RX-API-DMAC7.html)
WO (1) WO2010030697A1 (cg-RX-API-DMAC7.html)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10359425B2 (en) 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
JP2012520469A (ja) 2009-03-12 2012-09-06 キャンサー・プリヴェンション・アンド・キュア,リミテッド 性別に基づく疾病の識別・評価・予防及び治療を含む、肺病の識別・評価・予防及び治療の方法並びにそのキット
US20130116150A1 (en) 2010-07-09 2013-05-09 Somalogic, Inc. Lung Cancer Biomarkers and Uses Thereof
KR101857462B1 (ko) 2010-08-13 2018-05-14 소마로직, 인크. 췌장암 바이오마커 및 그것의 용도
CA2832480C (en) * 2011-04-07 2022-05-31 The Scripps Research Institute High-throughput screening for compounds modulating expression of cellular macromolecules
EP2702411A4 (en) * 2011-04-29 2015-07-22 Cancer Prevention & Cure Ltd METHOD FOR IDENTIFICATION AND DIAGNOSIS OF LUNG DISEASES USING CLASSIFICATION SYSTEMS AND KITS THEREFOR
EP2771692B1 (en) * 2011-10-24 2018-04-18 Somalogic, Inc. Lung cancer biomarkers and uses thereof
US9304137B2 (en) 2011-12-21 2016-04-05 Integrated Diagnostics, Inc. Compositions, methods and kits for diagnosis of lung cancer
US11913957B2 (en) 2011-12-21 2024-02-27 Biodesix, Inc. Compositions, methods and kits for diagnosis of lung cancer
AU2012358246B2 (en) 2011-12-21 2018-01-25 Integrated Diagnostics, Inc. Methods for diagnosis of lung cancer
CN104115150B (zh) * 2012-02-17 2018-05-04 皇家飞利浦有限公司 急性肺损伤(ali)/急性呼吸窘迫整合征(ards)评估和监测
WO2014074682A1 (en) 2012-11-07 2014-05-15 Somalogic, Inc. Chronic obstructive pulmonary disease (copd) biomarkers and uses thereof
KR102310799B1 (ko) * 2013-11-07 2021-10-12 미디얼 리서치 리미티드 폐암 위험 평가 방법 및 시스템
KR102087373B1 (ko) * 2015-09-11 2020-03-10 주식회사 압타머사이언스 비소세포성 폐암 진단용 단백질 바이오마커 패널 및 이를 이용한 비소세포성 폐암 진단 방법
FR3050269B1 (fr) * 2016-04-15 2018-05-11 Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris (Espci) Procede de selection et de recuperation de produits et systeme associe
CN105823665A (zh) * 2016-05-13 2016-08-03 北京九州柏林生物科技有限公司 生物组织样本制备套液
KR20190026769A (ko) 2016-06-21 2019-03-13 더 위스타 인스티튜트 오브 아나토미 앤드 바이올로지 유전자 발현 프로파일을 사용하여 폐암을 진단하기 위한 조성물 및 방법
JP6280997B1 (ja) * 2016-10-31 2018-02-14 株式会社Preferred Networks 疾患の罹患判定装置、疾患の罹患判定方法、疾患の特徴抽出装置及び疾患の特徴抽出方法
WO2018187496A2 (en) 2017-04-04 2018-10-11 Lung Cancer Proteomics, Llc Plasma based protein profiling for early stage lung cancer prognosis
EP3676393A4 (en) 2017-09-01 2021-10-13 Venn Biosciences Corporation IDENTIFICATION AND USE OF GLYCOPEPTIDES AS BIOMARKERS FOR DIAGNOSIS AND MONITORING OF TREATMENT
CN111630602A (zh) * 2017-11-22 2020-09-04 磨石肿瘤生物技术公司 减少新抗原的接合表位呈递
JP2021506308A (ja) 2017-12-19 2021-02-22 ザ・ウイスター・インステイテユート・オブ・アナトミー・アンド・バイオロジー 遺伝子発現プロファイルを使用して肺癌を診断するための組成物および方法
CN112638845B (zh) * 2018-06-22 2024-07-30 私募蛋白质体运营有限公司 改进的蛋白质组学多重测定
US20220397575A1 (en) * 2019-06-21 2022-12-15 National University Of Singapore Methods for determining the likelihood of lung cancer
CN110579611B (zh) * 2019-09-18 2023-01-31 郑州大学 一种用于肺癌早期筛查和诊断的联合检测血清标志物、试剂盒及检测方法
CN111047609B (zh) * 2020-03-13 2020-07-24 北京深睿博联科技有限责任公司 肺炎病灶分割方法和装置
CN113960235B (zh) * 2020-10-10 2023-03-14 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 生物标志物在制备肺癌检测试剂中的用途和方法
CN112557514B (zh) * 2020-12-22 2021-09-21 中国海洋大学 手持式海底沉积物样品剖面声学全自动测量装置
WO2025137139A1 (en) * 2023-12-18 2025-06-26 Caris Mpi, Inc. Dynamic tissue typing

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596503B1 (en) * 2000-08-18 2003-07-22 East Carolina University Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
US20030190602A1 (en) * 2001-03-12 2003-10-09 Monogen, Inc. Cell-based detection and differentiation of disease states
IL157872A0 (en) * 2001-03-12 2004-03-28 Monogen Inc A panel for detecting a generic disease state containing a plurality of probes and using cell-based diagnosis
EP1463928A2 (en) * 2001-04-18 2004-10-06 Protein Design Labs Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer
US8014952B2 (en) * 2002-12-18 2011-09-06 Queen Elizabeth Hospital Serum biomarkers in lung cancer
CN1225477C (zh) * 2003-03-28 2005-11-02 上海市疾病预防控制中心 肺癌早期血清特异蛋白及其应用
CN1455257A (zh) * 2003-05-23 2003-11-12 北京师范大学 一种利用表面修饰蛋白芯片进行肺癌诊断方法
ES2360073T3 (es) * 2004-03-23 2011-05-31 Oncotherapy Science, Inc. Método para diagnosticar cáncer de pulmón de células no pequeñas.
JP2005304497A (ja) * 2004-03-25 2005-11-04 Joji Inasawa 特定の癌関連遺伝子を用いる癌の検出方法及び癌の抑制方法
US7456027B2 (en) * 2004-04-15 2008-11-25 University Of Florida Research Foundation, Inc. Proteolytic biomarkers for traumatic injury to the nervous system
WO2005103281A2 (en) * 2004-04-26 2005-11-03 Children's Medical Center Corporation Platelet biomarkers for the detection of disease
AU2005278136A1 (en) * 2004-08-02 2006-03-02 Children's Medical Center Corporation Platelet biomarkers for cancer
CN1873417A (zh) * 2005-06-02 2006-12-06 中国医学科学院肿瘤医院肿瘤研究所 一种用于诊断肺癌的蛋白质芯片
JP5160447B2 (ja) * 2005-12-22 2013-03-13 アボット・ラボラトリーズ 肺がんへの傾向についてのスクリーニングのための方法およびマーカー組合せ
US7908091B2 (en) * 2006-03-17 2011-03-15 Prometheus Laboratories Inc. Methods of predicting and monitoring tyrosine kinase inhibitor therapy
US20080195327A1 (en) * 2006-10-17 2008-08-14 Synergenz Bioscience Limited Methods of Analysis of Polymorphisms and Uses Thereof
US20110119776A1 (en) * 2007-02-05 2011-05-19 Wong Kwok-Kin Methods of diagnosing and prognosing lung cancer
KR100846354B1 (ko) * 2007-03-21 2008-07-15 (주) 프로탄바이오 혈청 당단백질부터 분리한 폐암 진단용 마커
US20100184773A1 (en) * 2007-05-18 2010-07-22 Heinz-Josef Lenz Germline Polymorphisms in the Angiogenic Pathway Predict Tumor Recurrence in Cancer Therapy
WO2009036123A1 (en) * 2007-09-11 2009-03-19 Cancer Prevention And Cure, Ltd. Method of identifying biomarkers in human serum indicative of pathologies of human lung tissues
WO2010003772A1 (en) * 2008-06-16 2010-01-14 Siemens Medical Solutions Diagnostics Gmbh Method for predicting adverse response to erythropoietin in breast cancer treatment
US10359425B2 (en) * 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
CN102906275A (zh) * 2010-02-10 2013-01-30 加利福尼亚大学董事会 肺癌检测的唾液生物标记

Also Published As

Publication number Publication date
GB201106053D0 (en) 2011-05-25
AU2015249113B2 (en) 2017-09-07
CA3011730A1 (en) 2010-03-18
CA3152591C (en) 2023-08-29
WO2010030697A1 (en) 2010-03-18
MX2011002322A (es) 2011-05-10
HK1204062A1 (zh) 2015-11-06
CA2734535C (en) 2018-08-28
CA3011730C (en) 2022-05-17
HRP20160127T1 (hr) 2016-03-11
SI2340506T1 (sl) 2016-02-29
CN104198709A (zh) 2014-12-10
EP2340506B1 (en) 2015-11-11
CN102209968A (zh) 2011-10-05
AU2015249113A1 (en) 2015-11-12
DK2340506T3 (en) 2016-02-08
JP2012502281A (ja) 2012-01-26
AU2009291811A1 (en) 2010-03-18
KR20110063753A (ko) 2011-06-14
CA2734535A1 (en) 2010-03-18
HK1153834A1 (en) 2012-04-05
JP5701212B2 (ja) 2015-04-15
ES2559758T3 (es) 2016-02-15
EP2340506A4 (en) 2012-02-15
GB2478441A (en) 2011-09-07
AU2009291811B2 (en) 2015-10-29
EP2340506A1 (en) 2011-07-06
CN102209968B (zh) 2016-05-04
GB2478441B (en) 2013-03-27
CA3152591A1 (en) 2010-03-18

Similar Documents

Publication Publication Date Title
KR101658347B1 (ko) 폐암 바이오마커 및 그것들의 용도
KR101870123B1 (ko) 폐암 바이오마커 및 그것의 용도
KR101857462B1 (ko) 췌장암 바이오마커 및 그것의 용도
KR101921945B1 (ko) 폐암 바이오마커 및 그것의 용도
US20120143805A1 (en) Cancer Biomarkers and Uses Thereof
WO2011031344A1 (en) Cancer biomarkers and uses thereof
WO2013028807A2 (en) Renal cell carcinoma biomarkers and uses thereof
US20220065872A1 (en) Lung Cancer Biomarkers and Uses Thereof
HK1229002A1 (en) Lung cancer biomarkers and uses thereof
HK1229002A (en) Lung cancer biomarkers and uses thereof
HK1229002B (en) Lung cancer biomarkers and uses thereof
HK1229003A1 (en) Pancreatic cancer biomarkers and uses thereof
HK1196429B (en) Lung cancer biomarkers and uses thereof
HK1196429A (en) Lung cancer biomarkers and uses thereof

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20110307

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20140905

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20160330

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20160905

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20160912

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20160913

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
PR1001 Payment of annual fee

Payment date: 20190829

Start annual number: 4

End annual number: 4

PR1001 Payment of annual fee

Payment date: 20200828

Start annual number: 5

End annual number: 5

PR1001 Payment of annual fee

Payment date: 20210830

Start annual number: 6

End annual number: 6

PR1001 Payment of annual fee

Payment date: 20220829

Start annual number: 7

End annual number: 7

PR1001 Payment of annual fee

Payment date: 20230829

Start annual number: 8

End annual number: 8

PR1001 Payment of annual fee

Payment date: 20240827

Start annual number: 9

End annual number: 9