KR101606248B1 - 생물학적 활성 펩티드 - Google Patents

생물학적 활성 펩티드 Download PDF

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Publication number
KR101606248B1
KR101606248B1 KR1020137024826A KR20137024826A KR101606248B1 KR 101606248 B1 KR101606248 B1 KR 101606248B1 KR 1020137024826 A KR1020137024826 A KR 1020137024826A KR 20137024826 A KR20137024826 A KR 20137024826A KR 101606248 B1 KR101606248 B1 KR 101606248B1
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KR
South Korea
Prior art keywords
peptide
val trp
prt
artificial sequence
synthetic peptide
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1020137024826A
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English (en)
Korean (ko)
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KR20130112959A (ko
Inventor
프레드리히 슈에이플린거
미쉘 독칼
Original Assignee
백스터 인터내셔널 인코포레이티드
박스터 헬쓰케어 에스에이
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Publication of KR20130112959A publication Critical patent/KR20130112959A/ko
Application granted granted Critical
Publication of KR101606248B1 publication Critical patent/KR101606248B1/ko
Assigned to 박스앨타 게엠베하, 박스알타 인코퍼레이티드 reassignment 박스앨타 게엠베하 권리의 전부이전등록 Assignors: 박스터 헬쓰케어 에스에이, 백스터 인터내셔널 인코포레이티드
Assigned to 다케다 야쿠힌 고교 가부시키가이샤 reassignment 다케다 야쿠힌 고교 가부시키가이샤 권리의 전부이전등록 Assignors: 박스알타 인코퍼레이티드, 박스앨타 게엠베하
Expired - Fee Related legal-status Critical Current
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
KR1020137024826A 2008-04-17 2009-04-16 생물학적 활성 펩티드 Expired - Fee Related KR101606248B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US932608P 2008-04-17 2008-04-17
US61/009,326 2008-04-17
US11305508P 2008-11-10 2008-11-10
US61/113,055 2008-11-10
PCT/US2009/040857 WO2009137256A1 (en) 2008-04-17 2009-04-16 Biologically active peptides

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020107025687A Division KR101434712B1 (ko) 2008-04-17 2009-04-16 생물학적 활성 펩티드

Publications (2)

Publication Number Publication Date
KR20130112959A KR20130112959A (ko) 2013-10-14
KR101606248B1 true KR101606248B1 (ko) 2016-03-24

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KR1020137024826A Expired - Fee Related KR101606248B1 (ko) 2008-04-17 2009-04-16 생물학적 활성 펩티드
KR1020107025687A Expired - Fee Related KR101434712B1 (ko) 2008-04-17 2009-04-16 생물학적 활성 펩티드

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Country Status (19)

Country Link
US (6) US8563688B2 (https=)
EP (2) EP3115370B1 (https=)
JP (3) JP6038452B2 (https=)
KR (2) KR101606248B1 (https=)
CN (2) CN105524163A (https=)
AR (1) AR071478A1 (https=)
AU (1) AU2009244635B2 (https=)
BR (1) BRPI0911203A2 (https=)
CA (1) CA2721694C (https=)
DK (2) DK3115370T3 (https=)
ES (2) ES2739676T3 (https=)
HK (1) HK1223946A1 (https=)
MX (1) MX2010011397A (https=)
NZ (1) NZ588200A (https=)
PL (1) PL2279200T3 (https=)
PT (1) PT2279200T (https=)
SG (2) SG10201809286XA (https=)
TW (2) TWI573806B (https=)
WO (1) WO2009137256A1 (https=)

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TWI573806B (zh) * 2008-04-17 2017-03-11 巴克斯歐塔公司 生物活性胜肽
AU2010290131C1 (en) 2009-08-24 2015-12-03 Amunix Operating Inc. Coagulation factor VII compositions and methods of making and using same
CN103262532B (zh) 2010-07-19 2018-03-09 杜比实验室特许公司 用于经采样复用的图像和视频数据的增强方法
CA2838833A1 (en) 2011-06-10 2012-12-13 Biogen Idec Ma Inc. Pro-coagulant compounds and methods of use thereof
BR112014020694A2 (pt) 2012-02-15 2018-05-08 Amunix Operating Inc. proteína de fusão do fator viii compreendendo polipeptídeo do fator viii fusionado a polipeptí-deo recombinante estendido (xten) e seu método de fabricação, ácido nucleico, vetores, célula hospedeira, bem como composição farmacêutica e seu uso no tratamento de coagulopatia, episódio de hemorragia e hemofilia a
CA2864126A1 (en) 2012-02-15 2013-08-22 Biogen Idec Ma Inc. Recombinant factor viii proteins
HUE053223T2 (hu) * 2013-06-11 2021-06-28 Cj Cheiljedang Corp L-izoleucint termelõ mikroorganizmus és eljárás L-izoleucin elõállítására annak alkalmazásával
EP4108254A1 (en) 2013-08-14 2022-12-28 Bioverativ Therapeutics Inc. Recombinant factor viii proteins
US10548953B2 (en) 2013-08-14 2020-02-04 Bioverativ Therapeutics Inc. Factor VIII-XTEN fusions and uses thereof
US10584147B2 (en) 2013-11-08 2020-03-10 Biovertiv Therapeutics Inc. Procoagulant fusion compound
US20160039876A1 (en) 2014-03-28 2016-02-11 Claresa Levetan Insulin independence among patients with diabetes utilizing an optimized hamster reg3 gamma peptide
JP6484468B2 (ja) * 2014-06-03 2019-03-13 ＡｖａｎＳｔｒａｔｅ株式会社 ガラス板製造方法およびガラス板製造装置
GB201410507D0 (en) * 2014-06-12 2014-07-30 Univ Bath Drug delivery enhancement agents
BR112018002150A2 (pt) 2015-08-03 2018-09-18 Bioverativ Therapeutics Inc proteínas de fusão do fator ix e métodos de fabricação e uso das mesmas
TW201819398A (zh) 2016-09-28 2018-06-01 美商寇峇有限公司 治療性肽
IL319473A (en) 2016-12-02 2025-05-01 Bioverativ Therapeutics Inc Methods for treating hemophilic arthritis using chimeric blood clotting factors
CA3051862A1 (en) 2017-01-31 2018-08-09 Bioverativ Therapeutics Inc. Factor ix fusion proteins and methods of making and using same
BR112020022164A2 (pt) 2018-05-18 2021-02-02 Bioverativ Therapeutics Inc. métodos de tratamento de hemofilia a

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Also Published As

Publication number Publication date
HK1223946A1 (zh) 2017-08-11
EP2279200A1 (en) 2011-02-02
DK3115370T3 (da) 2019-07-29
US20120077749A1 (en) 2012-03-29
BRPI0911203A2 (pt) 2016-07-05
US8822638B2 (en) 2014-09-02
CN102007140B (zh) 2016-02-24
SG10201608071YA (en) 2016-11-29
TW201443085A (zh) 2014-11-16
HK1154255A1 (zh) 2012-04-13
US20100022445A1 (en) 2010-01-28
NZ588200A (en) 2012-11-30
AU2009244635A1 (en) 2009-11-12
US9206234B2 (en) 2015-12-08
AR071478A1 (es) 2010-06-23
MX2010011397A (es) 2010-11-12
US20150038676A1 (en) 2015-02-05
JP2014074052A (ja) 2014-04-24
JP5977223B2 (ja) 2016-08-24
ES2594706T3 (es) 2016-12-22
TWI573806B (zh) 2017-03-11
US20190225648A1 (en) 2019-07-25
EP3115370B1 (en) 2019-06-26
KR101434712B1 (ko) 2014-10-01
US20170174724A1 (en) 2017-06-22
TW200944226A (en) 2009-11-01
US10287319B2 (en) 2019-05-14
US20160060295A1 (en) 2016-03-03
CA2721694C (en) 2018-11-06
KR20130112959A (ko) 2013-10-14
DK2279200T3 (en) 2016-08-22
ES2739676T3 (es) 2020-02-03
CA2721694A1 (en) 2009-11-12
JP2011518179A (ja) 2011-06-23
PL2279200T3 (pl) 2017-08-31
US8563688B2 (en) 2013-10-22
CN102007140A (zh) 2011-04-06
PT2279200T (pt) 2016-10-12
EP3115370A1 (en) 2017-01-11
JP6038452B2 (ja) 2016-12-07
WO2009137256A1 (en) 2009-11-12
EP2279200B1 (en) 2016-07-13
TWI541020B (zh) 2016-07-11
US9598464B2 (en) 2017-03-21
KR20110005873A (ko) 2011-01-19
US10822376B2 (en) 2020-11-03
CN105524163A (zh) 2016-04-27
AU2009244635B2 (en) 2012-04-19
JP2017019797A (ja) 2017-01-26
SG10201809286XA (en) 2018-11-29

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