KR101566223B1 - Water-tissue containing extract of artemisia - Google Patents
Water-tissue containing extract of artemisia Download PDFInfo
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- KR101566223B1 KR101566223B1 KR1020150124006A KR20150124006A KR101566223B1 KR 101566223 B1 KR101566223 B1 KR 101566223B1 KR 1020150124006 A KR1020150124006 A KR 1020150124006A KR 20150124006 A KR20150124006 A KR 20150124006A KR 101566223 B1 KR101566223 B1 KR 101566223B1
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- extract
- wet tissue
- mugwort
- cleaning composition
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- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47K—SANITARY EQUIPMENT NOT OTHERWISE PROVIDED FOR; TOILET ACCESSORIES
- A47K7/00—Body washing or cleaning implements
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- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47K—SANITARY EQUIPMENT NOT OTHERWISE PROVIDED FOR; TOILET ACCESSORIES
- A47K10/00—Body-drying implements; Toilet paper; Holders therefor
- A47K10/16—Paper towels; Toilet paper; Holders therefor
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- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
The present invention relates to an antibacterial wet tissue comprising an mugwort extract.
Conventional wet tissue products are mainly used for wiping the skin when the baby is discharged from the cow or stool. Since these products are applied directly to the skin of weak baby, they are excellent in safety to the skin, and are resistant to foreign substances and pathogenic microorganisms It has a drawback in that it can not effectively prevent rash, red spot, and skin inflammation due to secondary infection caused by a pathogenic microorganism.
In addition, the conventional wet tissue products are susceptible to skin safety due to the occurrence of side effects at the time of use by adding a disinfectant, a surfactant, a chemical preservative, and an alcohol, which are known to have skin irritation, and the use of a disinfectant, alcohol, Which is unpleasant at the time of use, shows only a simple cleaning action on the surfactant and the alcohol component, and can not effectively protect the skin.
Recently, as interest in environment and health has increased, products using natural materials have been developed. Accordingly, products having natural materials added to wet tissues are being developed. Instead of simply adding natural materials, In this respect, improved demands are increasing.
As a related prior art, Korean Patent No. 10-2007-0112497 discloses a cosmetic composition having antimicrobial and antiseptic activity by using a natural extract of a cosmetic composition having antiseptic activity with gold, persimmon, mugwort, and citron extract. Korean Patent No. 10-2010-0098308 discloses a skin remedial lotion having antimicrobial, whitening and antioxidative activity using garlic and mugwort, which comprises natural antimicrobial activity of garlic and mugwort, and skin improvement A method of manufacturing a cosmetic lotion for use therein has been disclosed.
It is a technical object of the present invention to provide an antiseptic wet tissue containing a mugwort extract having a stable and antibacterial effect.
According to an aspect of the present invention,
The step of extracting the mugwort in methanol (CH 3 OH) from the extractor is repeated three times to obtain a mugwort extract; Preparing a cleaning composition comprising 5% by weight of zinc oxide and natural zeolite mixed with 2% by weight and 3: 7 of said extract, and purified water; and impregnating said cleaning composition with a nonwoven fabric. The present invention also provides a method for producing an antimicrobial wet tissue comprising the steps of:
In the present invention, the antimicrobial wet tissue may further include a warm antimicrobial agent or a natural antimicrobial agent.
Further, in the present invention, an antimicrobial wet tissue including an extract of mugwort including a nonwoven fabric impregnated with a cleaning composition containing zinc oxide and zeolite in an amount of 2% by weight, 3: 7 and 5% by weight of zeolite, to provide.
The antimicrobial wet tissue containing the mugwort extract of the present invention has an excellent antibacterial effect and an ammonia deodorizing effect, and the cleaning composition contained in the wet tissue has no side effect as a natural substance without irritation and non-toxicity. In addition, the cleaning composition contained in the wet tissue of the present invention has a good effect on the treatment of UV rays and acne.
FIG. 1 is a photographic view showing the effect of inhibiting microbial growth of Escherichia coli ATCC 25922 in the medium to which the cleaning composition of the control group and Production Examples 1 to 3 was added.
FIG. 2 is a photograph showing the inhibitory effect of K. pneumoniae ATCC 13883 on the growth of microorganisms in the medium containing the control group and the preparation examples 1 to 3. FIG.
Fig. 3 is a photograph showing the discoloration of the medium to which the cleaning composition of Production Example 2 was added on the day of manufacture and after 1 week to 3 weeks.
FIG. 4 is a photograph showing the microbial growth inhibitory effect of Super bacteria (gram-positive bacterium) MRSA (+) over time in the medium to which the cleaning composition of the control group and Production Examples 2 and 4 was added.
FIG. 5 is a photograph showing the microbial growth inhibitory effect of the standard strain (gram-bacteria bacterium) MSSA (+) over time in the medium to which the cleaning composition of the control and preparation examples 2 and 4 was added.
FIG. 6 is a photograph showing the microbial growth inhibitory effect of super bacteria (gram-negative bacteria) KPC (-) with time in the medium to which the cleaning composition of the control group and Production Examples 2 and 4 was added.
FIG. 7 is a photograph showing the microbial growth inhibitory effect of the standard strain (gram-bacteria bacterium) MSSA (+) in the medium to which the cleaning composition of the control group and the preparation examples 5 and 6 was added over time.
FIG. 8 is a photograph showing the microbial growth inhibitory effect of super bacteria (gram-negative bacteria) KPC (-) with time in the medium to which the cleaning composition of Controls and Production Examples 5 and 6 was added.
Hereinafter, the present invention will be described in more detail.
The present invention relates to an antimicrobial wet tissue including an extract of mugwort, more specifically, extracting a mugwort extract by methanol in an extractor to obtain a mugwort extract, A method for preparing an antimicrobial wet tissue including an extract of mugwort including a step of preparing a cleaning composition comprising zinc oxide mixed with 5 wt% of natural zeolite and purified water, and impregnating the cleaning composition with a nonwoven fabric, To an antimicrobial wet tissue produced by the method.
It is said to be a spike because it grows in the shore. It grows in the tidal flats of the beach or in a place that is submerged in seawater at high tide. Larval mugwort is more than twice as big as stemworm. The size of the gun is 5 ~ 7mm in diameter and 1 ~ 2mm in visor. It is known to have excellent ability to inhibit the proliferation of pathogenic bacteria that cause inflammatory diseases and skin infections. In addition to the medicinal effect of common mugwort, it is known that it is effective in gallbladder, kidney stones, hepatitis, and kidney salt because it has the effect of suppressing the occurrence of gallstones by smoothly releasing bile.
The antimicrobial wet tissue of the present invention has excellent antimicrobial action and excellent effect on acne bacteria by having the ability to inhibit the growth of pathogenic bacteria by including the extract of the mudflower extract.
The mugwort extract used in the present invention can be dried in a shade, dried in a hot-air dryer, and pulverized by a pulverizer to prepare a starting material of the extract. Thereafter, an extraction solvent is added to the starting material, the active ingredient is extracted at room temperature, and the solid material is removed by filtration, and the filtrate can be concentrated under reduced pressure.
The extraction solvent for extracting the active ingredient from the mugwort extract may be a nonpolar solvent or a polar solvent. The nonpolar solvent is hexane (n-hexane). The polar solvent includes alcohol (usually methyl alcohol or ethyl alcohol ), And medium ethyl acetate. When extracting physiologically active substances with hot water, since pure water is used as an extraction medium, there is no problem caused by the toxicity of the organic solvent used in the extraction. In some cases, hot water extraction may be performed for a long period of time , It may be necessary to extract a short time within 30 minutes. Therefore, it is important to set the extraction conditions through review of the literature prior to extraction. The extracts extracted with hot water are usually centrifuged, supernatant only, and lyophilized to produce powders and verify their physiological activity or commercialize them.
According to one embodiment of the present invention, the mugwort extract can be obtained by hot water extraction of mugwort, and the hot water extraction condition can be extracted at 75 to 85 ° C for 1 day to 3 days. Preferably, the mugwort is extracted with hot water at 80 ° C for 30 hours to obtain mugwort extract.
According to another embodiment of the present invention, the mugwort extract can be obtained by alcohol extraction (methyl alcohol (CH 3 OH)). The completely dried mugwort can be extracted in methyl alcohol (CH 3 OH) in an extractor and then extracted in a constant temperature water bath. The same procedure can be repeated 2 to 4 times to increase extraction yield of mugwort composition. If the number of times of extracting the mugwort is more than 3 times, the concentration of the extract becomes similar, so that the extraction process is preferably repeated three times.
The present invention provides a method for producing an antimicrobial wet tissue comprising the step of preparing a cleaning composition comprising 2 wt% of the above-mentioned wormwood extract, 5 wt% of zinc oxide mixed with 3: 7 and natural zeolite, and purified water.
It is known that zinc oxide is used as a raw material for UV blockers and has a good effect on treating acne. When such zinc oxide is mixed with zeolite which is a natural mineral, zinc zeolite is synthesized, and the antibacterial wet tissue of the present invention can have a bacterial, viral, fungus repellent and deodorizing effect and skin rash inhibiting effect. By setting the weight ratio of zinc oxide and natural zeolite to 3: 7, the effect of the zinc zeolite can be maximized, and ultraviolet shielding effect by zinc oxide and acne treatment effect can be produced. That is, when zinc oxide exceeds 30% by weight of the mixture of zinc oxide and natural zeolite, the antibacterial function is deteriorated. When the zinc oxide is less than 30% by weight, the effect of ultraviolet ray blocking and acne treatment does not occur.
The antimicrobial wet tissue of the present invention can enhance the antimicrobial function, ultraviolet ray blocking effect and acne treatment efficacy by synergistic effect of paper by mixing the mugwort extract, zinc oxide and natural zeolite at a specific ratio. 2% by weight of the mugwort extract, 5% by weight of zinc oxide mixed with 3: 7 and 5% by weight of natural zeolite, and purified water. When mixed at the above ratios, it is possible to maximize the antimicrobial function, UV-blocking effect and acne treatment effect of the mugwort extract and zinc oxide, natural zeolite, and there is little toxicity and side effects, so that it can be used safely even in long-term use.
In addition, the wet tissue according to the present invention may further include a microbial sterilization product. The microbial disinfectant may be defined as an aqueous solution or an aqueous dispersion containing a substance having a function of inhibiting or preventing microbial propagation and growth.
The microbial sterilization product is not particularly limited, but it may be a warm antimicrobial agent or a natural antimicrobial agent. Examples of the natural antimicrobial agent include wasabi extract and catechin. It is preferable that 0.001 to 0.01% by weight of the antimicrobial agent or the natural antimicrobial agent is contained in the microbial sterilizing product in order to exhibit a proper sterilizing power.
In addition to the detergent composition, the antimicrobial wet tissue according to the present invention may contain an emulsifying agent, a softening agent or a protective adjuvant, a stabilizer, a preservative, an antifungal agent, a skin protecting agent, a hydrating / wetting agent, a pH adjusting agent, a powder and a fragrance, and the like.
The present invention provides a method for producing an antibacterial wet tissue comprising the step of impregnating the nonwoven fabric with the cleaning composition. The nonwoven fabric to be used in the production of the present invention may be obtained by commercially available various nonwoven fabrics known in the art or may be prepared by various methods.
The nonwoven fabric that can be used in the present invention is not particularly limited, and for example, wet nonwoven fabric, dry nonwoven fabric, spunlace, spunbond, meltblown, needle punching, stitch bond, clara, coform fabric and the like can be used.
The nonwoven fabric is manufactured by mixing a plurality of kinds of raw cotton at a predetermined ratio and opening the raw cotton to finely untie them. The fibers supplied from the horn rim are combed and transferred to form a single fiber state A carding process for making the fibers into a thin film structure (web), a web laying process for laminating the web in the production of a thick product, A resin bonding process that binds the web by a deposition method, a printing method, or a spray method using an adhesive, a method in which moisture is evaporated from the adhesive by dry curing, 130, for 3 minutes), heat-bonding process that bonds the fibers by melting the fibers without using a resin adhesive ( thermal bonding process, a needle punching process in which the fibers are intertwined with each other by crossing several passes up and down, and even a dyeing or controlling process is carried out to spray the adhesive on the surface of the core so that the wick is adhered to the fabric It consists of a finishing process, an inspection process for selecting defective products, a winding process for winding the specified quantity, and a packaging process for packaging the finished product that has passed the quality inspection.
According to an embodiment of the present invention, it is preferable that the cleaning nonwoven fabric is impregnated with a pick-up ratio of 80 to 120%.
Hereinafter, the constitution and effects of the present invention will be described in more detail with reference to examples, comparative examples and test examples. However, these examples, comparative examples and test examples are provided for illustrative purposes only in order to facilitate understanding of the present invention, and the scope and scope of the present invention are not limited thereto.
< Example 1> Preparation of Mugwort Extract
Jejudo farms received the dunguswine from the well-winded and sunny day, turning it over daily, completely dried for 2 weeks, and then dried in a 60 hot air dryer for 2 ~ 3 days. Methyl alcohol (CH 3 OH) was completely immersed in the extract, and the extract was extracted in a constant temperature bath. The same procedure was repeated 3 times to increase the extraction yield of the mugwort extract. The extract was purified once using filter paper (Advantec NO. 2, filter paper), and the purified product was left in pure water extract of pure mugwort after removal of methyl alcohol in a vacuum condenser. Freeze-drying was carried out by freezing the extracts in advance, then sublimating the ice crystals produced in a high vacuum of 1 to 0.01 mmHg and drying for 24 hours. As a result of drying, extraction, and lyophilization, 1kg of mugwort was dried and about 450g of the extract was obtained by alcohol extraction method. After lyophilization, about 10g of mugwort extract was obtained.
< Example 2> Preparation of Cleaning Composition
The composition for cleaning was prepared by varying the composition as shown in Table 1 below.
< Test Example 1> Of the addition medium Evaluation of antibacterial activity
Escherichia coli ATCC 25922 strain and K. pneumoniae ATCC 13883 strain were adjusted to a Nephelometry Turbidity Unit (Nephel Method turbidity) of 0.5, and diluted 10-3 or 10-4 times to obtain a MacConkey agar medium and the above Preparation Examples 1, 2 and 3 Bacteria cultured overnight in a 36-temperature incubator in a medium prepared by adding a cleaning composition are shown in FIG. 1 and FIG. 2. FIG. As shown in FIG. 1 and FIG. 2, it can be seen that a large number of bacteria were cultured in the MacConkey agar medium. In particular, in the medium containing the cleaning composition of Production Examples 2 and 3, bacteria were hardly cultured, Excellent antimicrobial effect could be confirmed. Therefore, as in Production Example 2, it is considered that 2% by weight of Suiwon extract is sufficient.
3 shows the discoloration of the medium after the day of preparation of the medium and after 1 week to 3 weeks for the persistence test of the medium to which the cleaning composition of Preparation Example 2 was added. As shown in Fig. 3, discoloration of the medium could not be confirmed even for 3 weeks, and change in the inhibitory power against bacteria could not be confirmed. Therefore, various wipes such as an emulsifier, a stabilizer, a preservative, an antifungal agent, a pH adjuster, a skin protection agent and the like are added. However, when the cleaning composition of the present invention is used, the controversial set remimonium bromide, , Phenoxyethanol and the like are not contained, it can be used for a long time without deterioration.
After adjusting the Nephelometry Turbidity Unit (Nepali Method turbidity) to 0.5 for Super bacteria (Gram positive bacteria) MRSA (+), Standard strain (Gram bacteria bacterium) MSSA (+) and Super bacteria (Gram negative bacteria) KPC , the 10 -3 dilution in (1) was added to the cleaning composition of
As shown in FIG. 4, FIG. 5 and FIG. 6, it was confirmed that all of the bacteria disappeared within 3 hours only in the medium prepared by adding the cleaning composition of Preparation Example 2 (1). It was found that the medium prepared by adding the cleaning composition of Preparation Example 3 (3) did not die and only the culture was inhibited.
The standard strains MSSA (+) and super bacteria (Gram negative bacteria) KPC (-) were strained to a Nephelometry Turbidity Unit (Nephel Method turbidity) of 0.5 and diluted 10 -3 times The bacterial cells were cultured overnight in a 36-temperature incubator in a medium prepared by adding the cleaning composition of Example 6, (2) as a comparative example to a medium prepared by simply adding the cleaning composition of Production Example 5 to (3) 7 and 8, respectively.
As shown in Figs. 7 and 8, it was confirmed that all the bacteria disappeared within 3 hours only in the medium prepared by adding the cleaning composition of Production Example 5 (1). It was found that the medium prepared by adding the cleaning composition of Preparation Example 6 (3) inhibited the culture but did not die. That is, as shown in Production Example 2 of FIGS. 4, 5 and 6 (2) and Production Example 5 of FIG. 7 and FIG. 8 (1), the bacteria disappeared within 3 hours and zinc oxide When the natural zeolite mixture is 30% by weight or less and the natural zeolite is 70% or more, the antibacterial activity is excellent.
< Test Example 2> Safety evaluation for human skin
Fifty female subjects who met the criteria for clinical trials and did not meet the exclusion criteria were selected. The sample was applied to both arms and removed after 24 hours. After 2 hours from the removal, skin irritation such as erythema and itching was judged, and the judgment results are shown in Table 2 below.
As shown in Table 1, it was found that the cleaning composition of Preparation Example 2 was the most excellent in skin safety.
It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit or scope of the present invention as defined by the following claims. It can be understood that it is possible.
Claims (3)
The step of extracting the mugwort in methanol (CH 3 OH) from the extractor is repeated three times to obtain a mugwort extract;
Preparing a cleaning composition comprising zinc oxide and natural zeolite mixed at 2: 3 and 7: 3, and 5% by weight of purified water; And
Impregnating the nonwoven fabric with the cleaning composition,
Wherein the antimicrobial wet tissue further comprises 0.005% by weight of a warm antimicrobial agent or a natural antimicrobial agent, wherein the natural antimicrobial agent comprises any one of wasabi extract and catechin,
Wherein the cleaning composition is impregnated in the cleaning nonwoven fabric at a pick-up ratio of 100% in the impregnating step.
A method for producing an antimicrobial wet tissue including an extract of Mugwort.
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| KR1020150124006A KR101566223B1 (en) | 2015-09-02 | 2015-09-02 | Water-tissue containing extract of artemisia |
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| KR1020150124006A KR101566223B1 (en) | 2015-09-02 | 2015-09-02 | Water-tissue containing extract of artemisia |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106175542A (en) * | 2016-07-08 | 2016-12-07 | 浙江优全护理用品科技有限公司 | A kind of water can break up wet tissue of type natural degradation and preparation method thereof |
| KR20180115169A (en) * | 2017-04-12 | 2018-10-22 | 주식회사 지엘컴퍼니 | Cleansing composition comprising natural raw material extract and wet tissue comprising the same |
| KR101998522B1 (en) | 2018-08-01 | 2019-07-09 | 조원용 | Method for manufacturing environment friendly wet tissue containing green barley extracts for helping skin-moisture and preventing skin trouble |
| CN115387114A (en) * | 2022-10-26 | 2022-11-25 | 汕头市一针优品服装有限公司 | Finishing method of anti-mite bacteriostatic finishing agent for fiber fabric |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101548188B1 (en) | 2015-04-22 | 2015-08-31 | (주)태성바우 | Manufacturing method of wet tissue using foremost mugwort juice and mineral powder |
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2015
- 2015-09-02 KR KR1020150124006A patent/KR101566223B1/en active IP Right Grant
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101548188B1 (en) | 2015-04-22 | 2015-08-31 | (주)태성바우 | Manufacturing method of wet tissue using foremost mugwort juice and mineral powder |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106175542A (en) * | 2016-07-08 | 2016-12-07 | 浙江优全护理用品科技有限公司 | A kind of water can break up wet tissue of type natural degradation and preparation method thereof |
| KR20180115169A (en) * | 2017-04-12 | 2018-10-22 | 주식회사 지엘컴퍼니 | Cleansing composition comprising natural raw material extract and wet tissue comprising the same |
| KR101983990B1 (en) * | 2017-04-12 | 2019-05-31 | 주식회사 지엘컴퍼니 | Cleansing composition comprising natural raw material extract and wet tissue comprising the same |
| KR101998522B1 (en) | 2018-08-01 | 2019-07-09 | 조원용 | Method for manufacturing environment friendly wet tissue containing green barley extracts for helping skin-moisture and preventing skin trouble |
| CN115387114A (en) * | 2022-10-26 | 2022-11-25 | 汕头市一针优品服装有限公司 | Finishing method of anti-mite bacteriostatic finishing agent for fiber fabric |
| CN115387114B (en) * | 2022-10-26 | 2023-02-03 | 汕头市一针优品服装有限公司 | Finishing method of anti-mite and antibacterial finishing agent for fiber fabric |
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