KR101434612B1 - 사이클릭 나트륨 이뇨 펩타이드 구조물 - Google Patents
사이클릭 나트륨 이뇨 펩타이드 구조물 Download PDFInfo
- Publication number
- KR101434612B1 KR101434612B1 KR1020087026715A KR20087026715A KR101434612B1 KR 101434612 B1 KR101434612 B1 KR 101434612B1 KR 1020087026715 A KR1020087026715 A KR 1020087026715A KR 20087026715 A KR20087026715 A KR 20087026715A KR 101434612 B1 KR101434612 B1 KR 101434612B1
- Authority
- KR
- South Korea
- Prior art keywords
- aaa
- amino acid
- delete delete
- group
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 CC(C)CC(C)(C)C(C(O)=O)NC(C(C)(*)N)=O Chemical compound CC(C)CC(C)(C)C(C(O)=O)NC(C(C)(*)N)=O 0.000 description 7
- GRGBNVSKIVUKPD-UHFFFAOYSA-N CC(C)CC(C)(C)C(C(O)=O)N Chemical compound CC(C)CC(C)(C)C(C(O)=O)N GRGBNVSKIVUKPD-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74396106P | 2006-03-30 | 2006-03-30 | |
| US74396006P | 2006-03-30 | 2006-03-30 | |
| US60/743,960 | 2006-03-30 | ||
| US60/743,961 | 2006-03-30 | ||
| PCT/US2007/065645 WO2007115175A2 (en) | 2006-03-30 | 2007-03-30 | Cyclic natriuretic peptide constructs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20090025196A KR20090025196A (ko) | 2009-03-10 |
| KR101434612B1 true KR101434612B1 (ko) | 2014-08-26 |
Family
ID=38564246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020087026715A Expired - Fee Related KR101434612B1 (ko) | 2006-03-30 | 2007-03-30 | 사이클릭 나트륨 이뇨 펩타이드 구조물 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7622440B2 (enExample) |
| EP (1) | EP2001518B1 (enExample) |
| JP (1) | JP5355383B2 (enExample) |
| KR (1) | KR101434612B1 (enExample) |
| AU (1) | AU2007233116B2 (enExample) |
| BR (1) | BRPI0709427A2 (enExample) |
| CA (1) | CA2647143A1 (enExample) |
| CO (1) | CO6140040A2 (enExample) |
| DK (1) | DK2001518T3 (enExample) |
| EA (1) | EA016804B1 (enExample) |
| ES (1) | ES2430323T3 (enExample) |
| IL (1) | IL194262A (enExample) |
| MX (1) | MX2008012663A (enExample) |
| WO (1) | WO2007115175A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7795221B2 (en) | 2006-03-30 | 2010-09-14 | Palatin Technologies, Inc. | Linear natriuretic peptide constructs |
| US8114844B2 (en) | 2006-03-30 | 2012-02-14 | Palatin Technologies, Inc. | Linear and cyclic melanocortin receptor-specific peptidomimetics |
| US8580746B2 (en) * | 2006-03-30 | 2013-11-12 | Palatin Technologies, Inc. | Amide linkage cyclic natriuretic peptide constructs |
| US7964181B2 (en) * | 2006-03-30 | 2011-06-21 | Palatin Technologies, Inc. | Amino acid surrogates for peptidic constructs |
| EP2001518B1 (en) * | 2006-03-30 | 2013-07-10 | Palatin Technologies, Inc. | Cyclic natriuretic peptide constructs |
| MX2008012649A (es) * | 2006-03-30 | 2008-10-13 | Palatin Technologies Inc | Sustitutos de aminoacido para constructos peptidicos. |
| WO2010141845A2 (en) | 2009-06-05 | 2010-12-09 | 13Therapeutics, Inc. | Immunoregulatory peptides and methods of use |
| US9458198B1 (en) | 2009-06-26 | 2016-10-04 | Shire Orphan Therapies Gmbh | Cyclic peptide-based NPR-B agonists |
| UY32902A (es) * | 2009-09-25 | 2011-02-28 | Alcon Res Ltd | Nuevos agonistas de npr-b |
| AR078446A1 (es) | 2009-12-18 | 2011-11-09 | Alcon Res Ltd | Agonistas de npr-b. uso. |
| IE20100174A1 (en) * | 2010-03-25 | 2012-02-29 | Trinity College Dublin | Transdermal administration of peptides |
| CA2796725A1 (en) * | 2010-04-21 | 2011-10-27 | Palatin Technologies, Inc. | Uses of natriuretic peptide constructs |
| US8580748B2 (en) | 2011-04-06 | 2013-11-12 | 13Therapeutics, Inc. | Peptides for the treatment of hearing |
| KR101867026B1 (ko) | 2011-12-28 | 2018-07-20 | 대우조선해양 주식회사 | 밸러스트 수 처리 시스템의 미처리 수 처리 모듈 |
| EP3983437A1 (en) | 2019-06-12 | 2022-04-20 | Novartis AG | Natriuretic peptide receptor 1 antibodies and methods of use |
| KR20220045206A (ko) * | 2019-08-12 | 2022-04-12 | 바이오마린 파머수티컬 인크. | 연장 방출형 조성물을 위한 소수성 펩티드 염 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0223143A2 (en) * | 1985-11-05 | 1987-05-27 | California Biotechnology, Inc. | Analogs of atrial natriuretic peptides |
Family Cites Families (88)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4251438A (en) | 1979-06-14 | 1981-02-17 | The Upjohn Company | Piperazinone and piperazine polypeptides |
| US4341698A (en) | 1979-06-21 | 1982-07-27 | Richardson-Merrell Inc. | Enkaphalin derivatives |
| US4496544A (en) | 1983-11-10 | 1985-01-29 | Washington University | Atrial Peptides |
| US4952561A (en) | 1984-02-07 | 1990-08-28 | Merck & Co., Inc. | Cardiac atrial peptides |
| JPS60184098A (ja) | 1984-03-02 | 1985-09-19 | Suntory Ltd | 新規なペプチド及びこれを有効成分とする利尿剤 |
| US4618600A (en) | 1984-04-19 | 1986-10-21 | Biotechnology Research Associates, J.V. | Novel polypeptide diuretic/vasodilators |
| US5212286A (en) | 1984-04-19 | 1993-05-18 | Scios Nova Inc. | Atrial natriuretic/vasodilator peptide compounds |
| JPH0780907B2 (ja) | 1984-04-19 | 1995-08-30 | シオス・ノバ・インク | 新規な心房性ナトリウム尿排泄亢進性及び血管拡張性ポリペプチド |
| WO1985004872A1 (en) | 1984-04-24 | 1985-11-07 | The Salk Institute For Biological Studies | Atrial peptide analogs |
| JPH0672155B2 (ja) | 1984-08-24 | 1994-09-14 | 塩野義製薬株式会社 | α−hANP抗血清作製用ポリペプチド |
| US4609725A (en) | 1984-10-09 | 1986-09-02 | Merck & Co., Inc. | Cardiac atrial peptides |
| US4757048A (en) | 1985-11-05 | 1988-07-12 | Biotechnology Research Associates J.V. | Synthetic analogs of atrial natriuretic peptides |
| DE3614833A1 (de) | 1986-01-16 | 1987-07-23 | Hoechst Ag | Peptide mit vasorelaxierender, natriuretischer und diuretischer wirkung, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung |
| US5057603A (en) | 1986-01-31 | 1991-10-15 | Merck & Co., Inc. | Peptides having ANF activity |
| US4716147A (en) | 1986-03-27 | 1987-12-29 | Monsanto Company | Synthetic airial peptides |
| EP0246795A3 (en) | 1986-05-20 | 1990-04-04 | Advanced Peptide Development Limited | Synthetic natriuretic peptides |
| US5159061A (en) | 1986-09-29 | 1992-10-27 | Takeda Chemical Industries, Ltd. | Atrial natriuretic peptide derivative |
| US4804650A (en) | 1986-10-28 | 1989-02-14 | Biotechnology Research Associates, J.V. | Analogs of atrial natriuretic peptides |
| DK531986D0 (da) | 1986-11-07 | 1986-11-07 | Novo Industri As | Peptider |
| DE3878231T2 (de) | 1987-03-02 | 1993-05-27 | Bissendorf Peptide Gmbh | Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung. |
| US5095004A (en) | 1987-03-25 | 1992-03-10 | Bio-Mega Inc. | Fluorine containing atrial natriuretic peptides |
| US5376635A (en) | 1987-03-15 | 1994-12-27 | Bio-Mega/Boehringer Ingelheim Research Inc. | Fluorine containing atrial natriuretic peptides |
| US5091366A (en) | 1987-05-19 | 1992-02-25 | Merck & Co., Inc. | Peptides having ANF activity |
| US4816443A (en) | 1987-05-19 | 1989-03-28 | Merck & Co., Inc. | Piptides having ANF activity |
| IL86386A0 (en) | 1987-05-21 | 1988-11-15 | Merrell Dow Pharma | Novel anf derivatives |
| JP2544929B2 (ja) | 1987-06-17 | 1996-10-16 | 第一化学薬品 株式会社 | 新規生理活性ペプチド |
| US4935492A (en) | 1987-12-24 | 1990-06-19 | California Biotechnology Inc. | Cyclic analogs of atrial natriuretic peptides |
| US5047397A (en) | 1988-08-26 | 1991-09-10 | California Biotechnology Inc. | Linear analogs of atrial natriuretic peptides |
| JP2855143B2 (ja) | 1987-12-24 | 1999-02-10 | サイオス インコーポレイテッド | 心房の,ナトリウム排出亢進性ペプチドの直鎖アナログ |
| EP0341603A3 (en) | 1988-05-09 | 1990-07-04 | Abbott Laboratories | Atrial peptide derivatives |
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| US5057495A (en) | 1988-06-24 | 1991-10-15 | Queen's University At Kingston | Atrial hypotensive peptide |
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| AU4211989A (en) | 1988-08-18 | 1990-03-23 | California Biotechnology, Inc. | Atrial natriuretic peptide clearance inhibitors |
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| EP0385476B2 (en) | 1989-03-01 | 1999-09-22 | SHIONOGI & CO., LTD. | Physiologically active polypeptide and DNA |
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| ATE164080T1 (de) | 1990-05-10 | 1998-04-15 | Bechgaard Int Res | Pharmazeutische zubereitung enthaltend n- glykofurole und n-äthylenglykole |
| US5204328A (en) | 1990-06-26 | 1993-04-20 | Merck & Co., Inc. | Peptides having atrial natriuretic factor activity |
| US5202239A (en) | 1990-08-07 | 1993-04-13 | Scios Nova Inc. | Expression of recombinant polypeptides with improved purification |
| JPH06501950A (ja) | 1990-10-11 | 1994-03-03 | ベーリンガー インゲルハイム コマンディトゲゼルシャフト | 環状ペプチド、その調製法およびその薬理組成物としての使用 |
| JP2809533B2 (ja) | 1991-01-31 | 1998-10-08 | 壽之 松尾 | Cnp類似体ペプチド |
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| JP2008509746A (ja) | 2004-08-11 | 2008-04-03 | アルザ・コーポレーシヨン | ナトリウム利尿ペプチドを経皮送達する器具および方法 |
| US7795221B2 (en) | 2006-03-30 | 2010-09-14 | Palatin Technologies, Inc. | Linear natriuretic peptide constructs |
| EP2001518B1 (en) * | 2006-03-30 | 2013-07-10 | Palatin Technologies, Inc. | Cyclic natriuretic peptide constructs |
-
2007
- 2007-03-30 EP EP07759833.2A patent/EP2001518B1/en active Active
- 2007-03-30 KR KR1020087026715A patent/KR101434612B1/ko not_active Expired - Fee Related
- 2007-03-30 CA CA002647143A patent/CA2647143A1/en not_active Abandoned
- 2007-03-30 US US11/694,260 patent/US7622440B2/en active Active
- 2007-03-30 BR BRPI0709427-2A patent/BRPI0709427A2/pt not_active IP Right Cessation
- 2007-03-30 MX MX2008012663A patent/MX2008012663A/es active IP Right Grant
- 2007-03-30 ES ES07759833T patent/ES2430323T3/es active Active
- 2007-03-30 JP JP2009503312A patent/JP5355383B2/ja not_active Expired - Fee Related
- 2007-03-30 AU AU2007233116A patent/AU2007233116B2/en not_active Ceased
- 2007-03-30 DK DK07759833.2T patent/DK2001518T3/da active
- 2007-03-30 WO PCT/US2007/065645 patent/WO2007115175A2/en not_active Ceased
- 2007-03-30 EA EA200802059A patent/EA016804B1/ru not_active IP Right Cessation
-
2008
- 2008-09-22 IL IL194262A patent/IL194262A/en not_active IP Right Cessation
- 2008-10-30 CO CO08116413A patent/CO6140040A2/es unknown
-
2009
- 2009-11-19 US US12/622,055 patent/US8580747B2/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0223143A2 (en) * | 1985-11-05 | 1987-05-27 | California Biotechnology, Inc. | Analogs of atrial natriuretic peptides |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007233116A1 (en) | 2007-10-11 |
| IL194262A (en) | 2014-05-28 |
| WO2007115175A2 (en) | 2007-10-11 |
| EP2001518B1 (en) | 2013-07-10 |
| CO6140040A2 (es) | 2010-03-19 |
| WO2007115175A3 (en) | 2008-12-11 |
| EA016804B1 (ru) | 2012-07-30 |
| US20070265206A1 (en) | 2007-11-15 |
| ES2430323T3 (es) | 2013-11-20 |
| KR20090025196A (ko) | 2009-03-10 |
| BRPI0709427A2 (pt) | 2011-07-12 |
| EA200802059A1 (ru) | 2009-04-28 |
| HK1134022A1 (en) | 2010-04-16 |
| MX2008012663A (es) | 2008-10-13 |
| EP2001518A2 (en) | 2008-12-17 |
| AU2007233116B2 (en) | 2013-05-09 |
| US8580747B2 (en) | 2013-11-12 |
| JP2009532384A (ja) | 2009-09-10 |
| US20100075895A1 (en) | 2010-03-25 |
| US7622440B2 (en) | 2009-11-24 |
| EP2001518A4 (en) | 2009-11-04 |
| DK2001518T3 (da) | 2013-10-07 |
| CA2647143A1 (en) | 2007-10-11 |
| JP5355383B2 (ja) | 2013-11-27 |
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