KR101426070B1 - Cd36 발현을 감소시키는 방법 - Google Patents
Cd36 발현을 감소시키는 방법 Download PDFInfo
- Publication number
- KR101426070B1 KR101426070B1 KR1020087009150A KR20087009150A KR101426070B1 KR 101426070 B1 KR101426070 B1 KR 101426070B1 KR 1020087009150 A KR1020087009150 A KR 1020087009150A KR 20087009150 A KR20087009150 A KR 20087009150A KR 101426070 B1 KR101426070 B1 KR 101426070B1
- Authority
- KR
- South Korea
- Prior art keywords
- aromatic
- expression
- amino acids
- peptide
- phe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/03—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biotechnology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71817005P | 2005-09-16 | 2005-09-16 | |
| US60/718,170 | 2005-09-16 | ||
| PCT/US2006/036291 WO2007035640A2 (en) | 2005-09-16 | 2006-09-18 | Methods for reducing cd36 expression |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020147007878A Division KR20140042940A (ko) | 2005-09-16 | 2006-09-18 | Cd36 발현을 감소시키는 방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20080050497A KR20080050497A (ko) | 2008-06-05 |
| KR101426070B1 true KR101426070B1 (ko) | 2014-08-01 |
Family
ID=37889419
Family Applications (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020087009150A Active KR101426070B1 (ko) | 2005-09-16 | 2006-09-18 | Cd36 발현을 감소시키는 방법 |
| KR1020157000639A Ceased KR20150013353A (ko) | 2005-09-16 | 2006-09-18 | Cd36 발현을 감소시키는 방법 |
| KR1020157000640A Active KR101621493B1 (ko) | 2005-09-16 | 2006-09-18 | Cd36 발현을 감소시키는 방법 |
| KR1020147007878A Ceased KR20140042940A (ko) | 2005-09-16 | 2006-09-18 | Cd36 발현을 감소시키는 방법 |
| KR1020147021832A Ceased KR20140106761A (ko) | 2005-09-16 | 2006-09-18 | Cd36 발현을 감소시키는 방법 |
| KR1020160056491A Ceased KR20160056863A (ko) | 2005-09-16 | 2016-05-09 | Cd36 발현을 감소시키는 방법 |
| KR1020160057030A Ceased KR20160057372A (ko) | 2005-09-16 | 2016-05-10 | Cd36 발현을 감소시키는 방법 |
| KR1020170115440A Active KR101999756B1 (ko) | 2005-09-16 | 2017-09-08 | Cd36 발현을 감소시키는 방법 |
| KR1020190082102A Ceased KR20190084025A (ko) | 2005-09-16 | 2019-07-08 | Cd36 발현을 감소시키는 방법 |
Family Applications After (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157000639A Ceased KR20150013353A (ko) | 2005-09-16 | 2006-09-18 | Cd36 발현을 감소시키는 방법 |
| KR1020157000640A Active KR101621493B1 (ko) | 2005-09-16 | 2006-09-18 | Cd36 발현을 감소시키는 방법 |
| KR1020147007878A Ceased KR20140042940A (ko) | 2005-09-16 | 2006-09-18 | Cd36 발현을 감소시키는 방법 |
| KR1020147021832A Ceased KR20140106761A (ko) | 2005-09-16 | 2006-09-18 | Cd36 발현을 감소시키는 방법 |
| KR1020160056491A Ceased KR20160056863A (ko) | 2005-09-16 | 2016-05-09 | Cd36 발현을 감소시키는 방법 |
| KR1020160057030A Ceased KR20160057372A (ko) | 2005-09-16 | 2016-05-10 | Cd36 발현을 감소시키는 방법 |
| KR1020170115440A Active KR101999756B1 (ko) | 2005-09-16 | 2017-09-08 | Cd36 발현을 감소시키는 방법 |
| KR1020190082102A Ceased KR20190084025A (ko) | 2005-09-16 | 2019-07-08 | Cd36 발현을 감소시키는 방법 |
Country Status (10)
| Country | Link |
|---|---|
| US (10) | US7541340B2 (enExample) |
| EP (5) | EP3260127B1 (enExample) |
| JP (6) | JP5416971B2 (enExample) |
| KR (9) | KR101426070B1 (enExample) |
| CN (6) | CN107412723A (enExample) |
| AU (1) | AU2006292352B2 (enExample) |
| CA (8) | CA2947343C (enExample) |
| DK (1) | DK1931369T3 (enExample) |
| HK (1) | HK1206971A1 (enExample) |
| WO (1) | WO2007035640A2 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2656854T1 (sl) | 2003-02-04 | 2015-09-30 | Cornell Research Foundation, Inc. | Uporabe aromatsko-kationskega peptida |
| US7704954B2 (en) | 2003-05-01 | 2010-04-27 | Cornell Research Foundation, Inc. | Method and carrier complexes for delivering molecules to cells |
| CA3024434A1 (en) * | 2004-01-23 | 2005-08-11 | Cornell Research Foundation, Inc. | Methods for reducing oxidative damage |
| US7687243B1 (en) * | 2005-06-06 | 2010-03-30 | Crook Tonia M | Automated method for detecting apoptosis in cells |
| CA2947343C (en) | 2005-09-16 | 2019-04-30 | Cornell Research Foundation, Inc. | Methods for reducing cd36 expression |
| PT2252312E (pt) * | 2008-02-07 | 2014-07-17 | Univ Cornell | Métodos de prevenção ou tratamento de resistência a insulina |
| CN107802821A (zh) * | 2008-02-26 | 2018-03-16 | 康奈尔大学 | 用于防止和治疗急性肾损伤的方法 |
| EP3563862B1 (en) * | 2009-03-20 | 2021-05-05 | The General Hospital Corporation d/b/a Massachusetts General Hospital | D-arg-2'6'-dimethyltyrosine-lys-phe-nh2 for use in the prevention of secondary complications of burn injuries |
| CN105031605A (zh) * | 2009-08-12 | 2015-11-11 | 康奈尔大学 | 预防或治疗代谢综合症的方法 |
| SMT202300433T1 (it) | 2009-08-24 | 2024-01-10 | Stealth Biotherapeutics Inc | Peptide per l'uso nella prevenzione o nel trattamento della degenerazione maculare |
| US20110082084A1 (en) | 2009-10-05 | 2011-04-07 | Szeto Hazel H | Methods for the prevention or treatment of heart failure |
| CA2786280A1 (en) * | 2009-12-31 | 2011-07-07 | Stealth Peptides International, Inc. | Methods for the prevention or treatment of vessel occlusion injury |
| AU2010339414A1 (en) * | 2009-12-31 | 2012-07-19 | Stealth Peptides International, Inc. | Methods for performing a coronary artery bypass graft procedure |
| CN103037901B (zh) * | 2010-06-01 | 2018-04-27 | 康奈尔大学 | 抑制cd36以控制肥胖和胰岛素敏感性 |
| EP3539554A1 (en) * | 2010-07-09 | 2019-09-18 | Stealth Peptides International, Inc. | Methods for the prevention or treatment of no-reflow following ischemia/reperfusion injury |
| HK1204988A1 (en) * | 2012-02-22 | 2015-12-11 | Stealth Peptides International, Inc. | Methods and compositions for preventing or treating ophthalmic conditions |
| WO2013149172A1 (en) * | 2012-03-30 | 2013-10-03 | Stealth Peptides International, Inc. | Methods and compositions for the prevention and treatment neuropathy |
| CN104661670A (zh) * | 2012-08-02 | 2015-05-27 | 康肽德生物医药技术有限公司 | 用于治疗动脉粥样硬化的方法 |
| CN105051534B (zh) * | 2012-12-18 | 2017-08-18 | 佰鸥科瑞公司 | 用于治疗和/或限制糖尿病发展的方法 |
| EP3586864A1 (en) * | 2013-05-14 | 2020-01-01 | Stealth Biotherapeutics Corp | Methods for the prevention or treatment of left ventricle remodeling |
| CA2916492A1 (en) * | 2013-06-27 | 2014-12-31 | Stealth Biotherapeutics Corp | Peptide therapeutics and methods for using same |
| CA2925757A1 (en) * | 2013-09-30 | 2015-04-02 | Cornell University | Cardiolipin-targeted peptides inhibit beta-amyloid oligomer toxicity |
| WO2015089316A1 (en) * | 2013-12-12 | 2015-06-18 | Cornell University | Methods for preventing and treating oral cancers |
| EP3082838A4 (en) * | 2013-12-16 | 2017-07-26 | Cornell University | Methods and compositions for treating and preventing cognitive dysfunction |
| CN107041946A (zh) * | 2017-03-24 | 2017-08-15 | 南京大学 | 化合物ss‑31在制备治疗动脉粥样硬化及相关疾病药物或制剂上的应用 |
| US11392555B2 (en) | 2019-05-15 | 2022-07-19 | Pure Storage, Inc. | Cloud-based file services |
| WO2021021452A1 (en) * | 2019-07-26 | 2021-02-04 | The Board Of Trustees Of The Leland Stanford Junior University | 1,8-cineol coated implants |
| CN115279394A (zh) | 2019-11-20 | 2022-11-01 | 斯坦福大学托管董事会 | 用于放射治疗的预防性皮肤治疗 |
| CN117881411A (zh) | 2021-06-01 | 2024-04-12 | 艾迪雅生物有限责任公司 | 用于眼部药物的延长释放药物递送系统和使用方法 |
| WO2025021993A1 (en) | 2023-07-27 | 2025-01-30 | Omnilinx Therapeutics Ag | Endocytic and scavenger receptor-targeting chimeric proteins and uses thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004075856A2 (en) | 2003-02-24 | 2004-09-10 | Novacardia, Inc. | Adenosine a1 receptor antagonist for the treatment of cardiac and renal diseases |
| WO2005055706A1 (ja) | 2003-12-12 | 2005-06-23 | Japan Science And Technology Agency | メグシン/RAGE/iNOS発現疾患モデル動物及び該動物を用いた化合物の評価方法 |
| WO2005072295A2 (en) * | 2004-01-23 | 2005-08-11 | Cornell Research Foundation, Inc. | Methods for reducing oxidative damage |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| ES2085865T3 (es) * | 1988-06-30 | 1996-06-16 | Astra Ab | Analogos de dermorfina, sus metodos de preparacion, composiciones farmaceuticas, y metodos de tratamiento terapeutico que los emplean. |
| US5602100A (en) * | 1988-06-30 | 1997-02-11 | Astra Ab | Dermorphin analogs having pharmacological activity |
| US5747641A (en) * | 1989-12-21 | 1998-05-05 | Biogen Inc | Tat-derived transport polypeptide conjugates |
| US5858784A (en) | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
| US5674534A (en) | 1992-06-11 | 1997-10-07 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5716644A (en) | 1992-06-11 | 1998-02-10 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| IS4261A (is) | 1994-02-21 | 1995-08-22 | Astra Aktiebolag | Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra |
| DE69630918T2 (de) * | 1995-06-09 | 2004-10-28 | Hisamitsu Pharmaceutical Co., Inc., Tosu | Matrix für Iontophorese |
| US5849761A (en) * | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
| FR2756284B1 (fr) * | 1996-11-26 | 2000-04-28 | Adir | Nouveaux derives du benzopyrane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US5885958A (en) * | 1997-03-25 | 1999-03-23 | Administrators Of The Tulane Educational Fund | Mu-opiate receptor peptides |
| US5989463A (en) | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
| JP2002505077A (ja) * | 1997-12-10 | 2002-02-19 | ワシントン大学 | 抗病原体システムおよびその使用方法 |
| EP1071414A1 (en) * | 1998-04-24 | 2001-01-31 | Mitokor | Compounds and methods for treating mitochondria-associated diseases |
| US6245740B1 (en) | 1998-12-23 | 2001-06-12 | Amgen Inc. | Polyol:oil suspensions for the sustained release of proteins |
| SE9900961D0 (sv) * | 1999-03-16 | 1999-03-16 | Astra Ab | Novel compounds |
| US6503713B1 (en) * | 1999-10-04 | 2003-01-07 | University Of Medicine And Dentistry Of New Jersey | Methods for identifying RNA binding compounds |
| US6759520B1 (en) * | 1999-10-28 | 2004-07-06 | The New England Medical Center Hospitals, Inc. | Chimeric analgesic peptides |
| US20050192215A1 (en) * | 2000-01-21 | 2005-09-01 | Malabika Ghosh | Methods and materials relating to novel polypeptides and polynucleotides |
| US7498297B2 (en) * | 2000-07-18 | 2009-03-03 | Cornell Research Foundation | Medicinal uses of mu-opioid receptor agonists |
| US6900178B2 (en) * | 2000-09-12 | 2005-05-31 | University Of Kentucky Research Foundation | Protection against ischemia and reperfusion injury |
| DE10051983A1 (de) | 2000-10-20 | 2002-06-13 | Beate Kehrel | Inhibierung der pathogenen Wirkung oxidierter Proteine |
| ATE406908T1 (de) * | 2000-10-20 | 2008-09-15 | Hamburger Stiftung Zur Foerder | Oxidierte proteine und deren biologische und therapeutische aktivität sowie diagnostische verwendung über die hemmung der interaktion zwischen oxidierten proteinen und cd36 |
| US20040115261A1 (en) | 2001-04-05 | 2004-06-17 | Ashley Robert A. | Controlled delivery of tetracycline compounds and tetracycline derivatives |
| US20070015146A1 (en) | 2001-05-22 | 2007-01-18 | Gene Logic, Inc. | Molecular nephrotoxicology modeling |
| AU2002360460A1 (en) * | 2001-12-03 | 2003-06-17 | Nuvelo, Inc. | Methods and materials relating to novel polypeptides and polynucleotides |
| JP4346870B2 (ja) * | 2002-07-05 | 2009-10-21 | キッコーマン株式会社 | 血糖値上昇抑制用組成物 |
| US7785567B2 (en) * | 2002-08-23 | 2010-08-31 | Valorisation-Recherche, Société en Commandite | Growth hormone-releasing peptides in the treatment or prevention of atherosclerosis and hypercholesterolemia |
| SI2656854T1 (sl) * | 2003-02-04 | 2015-09-30 | Cornell Research Foundation, Inc. | Uporabe aromatsko-kationskega peptida |
| US7704954B2 (en) * | 2003-05-01 | 2010-04-27 | Cornell Research Foundation, Inc. | Method and carrier complexes for delivering molecules to cells |
| KR20060026011A (ko) | 2003-05-09 | 2006-03-22 | 노보 노르디스크 에이/에스 | 비만 치료용 펩티드 |
| US20050012597A1 (en) | 2003-07-02 | 2005-01-20 | Anderson Peter Traneus | Wireless electromagnetic tracking system using a nonlinear passive transponder |
| WO2005032481A2 (en) * | 2003-09-30 | 2005-04-14 | Scios Inc. | Quinazoline derivatives as medicaments |
| EP1529533A1 (en) * | 2003-11-06 | 2005-05-11 | Sahltech I Göteborg AB | Use of GH secretagogues in hypoxic-ischemic brain injury |
| US20050272101A1 (en) | 2004-06-07 | 2005-12-08 | Prasad Devarajan | Method for the early detection of renal injury |
| US8157123B2 (en) * | 2005-02-23 | 2012-04-17 | The Glad Products Company | Container |
| CA2947343C (en) * | 2005-09-16 | 2019-04-30 | Cornell Research Foundation, Inc. | Methods for reducing cd36 expression |
| US20070259377A1 (en) * | 2005-10-11 | 2007-11-08 | Mickey Urdea | Diabetes-associated markers and methods of use thereof |
| US20080027082A1 (en) | 2006-06-19 | 2008-01-31 | Berthold Hocher | Use of adenosine a1 antagonists in radiocontrast media induced nephropathy |
| PT2252312E (pt) * | 2008-02-07 | 2014-07-17 | Univ Cornell | Métodos de prevenção ou tratamento de resistência a insulina |
| CN107802821A (zh) | 2008-02-26 | 2018-03-16 | 康奈尔大学 | 用于防止和治疗急性肾损伤的方法 |
| JP2012181082A (ja) * | 2011-03-01 | 2012-09-20 | Tokyo Electric Power Co Inc:The | 仕切弁の分解点検補助装置およびその案内治具、並びに仕切弁の分解点検方法 |
| CN202756379U (zh) | 2012-07-13 | 2013-02-27 | 滨中元川金属制品(昆山)有限公司 | 一种自攻牙螺丝 |
-
2006
- 2006-09-18 CA CA2947343A patent/CA2947343C/en active Active
- 2006-09-18 CA CA2947333A patent/CA2947333A1/en not_active Abandoned
- 2006-09-18 KR KR1020087009150A patent/KR101426070B1/ko active Active
- 2006-09-18 CA CA2947328A patent/CA2947328C/en active Active
- 2006-09-18 EP EP17172250.7A patent/EP3260127B1/en active Active
- 2006-09-18 CA CA2947335A patent/CA2947335A1/en not_active Abandoned
- 2006-09-18 JP JP2008531412A patent/JP5416971B2/ja active Active
- 2006-09-18 CA CA2947341A patent/CA2947341C/en active Active
- 2006-09-18 WO PCT/US2006/036291 patent/WO2007035640A2/en not_active Ceased
- 2006-09-18 US US11/532,764 patent/US7541340B2/en active Active
- 2006-09-18 KR KR1020157000639A patent/KR20150013353A/ko not_active Ceased
- 2006-09-18 AU AU2006292352A patent/AU2006292352B2/en active Active
- 2006-09-18 KR KR1020157000640A patent/KR101621493B1/ko active Active
- 2006-09-18 EP EP19160103.8A patent/EP3549594A1/en not_active Withdrawn
- 2006-09-18 CN CN201610884213.4A patent/CN107412723A/zh active Pending
- 2006-09-18 KR KR1020147007878A patent/KR20140042940A/ko not_active Ceased
- 2006-09-18 CN CN201210028972.2A patent/CN102552874B/zh active Active
- 2006-09-18 CA CA2947340A patent/CA2947340C/en active Active
- 2006-09-18 DK DK06814864.2T patent/DK1931369T3/en active
- 2006-09-18 KR KR1020147021832A patent/KR20140106761A/ko not_active Ceased
- 2006-09-18 CA CA2947330A patent/CA2947330C/en active Active
- 2006-09-18 EP EP20167024.7A patent/EP3725324A1/en active Pending
- 2006-09-18 CN CN201410509385.4A patent/CN104324360A/zh active Pending
- 2006-09-18 CA CA2622911A patent/CA2622911C/en active Active
- 2006-09-18 CN CN201310627156.8A patent/CN103784937B/zh active Active
- 2006-09-18 EP EP16176957.5A patent/EP3095454A1/en not_active Withdrawn
- 2006-09-18 CN CN2006800400192A patent/CN101296704B/zh active Active
- 2006-09-18 CN CN201510142734.8A patent/CN104788540B/zh active Active
- 2006-09-18 EP EP06814864.2A patent/EP1931369B1/en active Active
-
2009
- 2009-05-01 US US12/434,216 patent/US7811987B2/en active Active
-
2010
- 2010-08-04 US US12/850,079 patent/US8603971B2/en active Active
-
2012
- 2012-08-17 JP JP2012181082A patent/JP5805596B2/ja active Active
-
2013
- 2013-01-17 JP JP2013006199A patent/JP5809649B2/ja active Active
- 2013-11-08 US US14/075,686 patent/US9150614B2/en active Active
-
2014
- 2014-05-22 US US14/285,226 patent/US20140256620A1/en not_active Abandoned
-
2015
- 2015-06-08 JP JP2015115856A patent/JP6157539B2/ja active Active
- 2015-08-04 HK HK15107494.9A patent/HK1206971A1/xx unknown
- 2015-08-07 JP JP2015156656A patent/JP6175107B2/ja active Active
-
2016
- 2016-05-09 KR KR1020160056491A patent/KR20160056863A/ko not_active Ceased
- 2016-05-10 KR KR1020160057030A patent/KR20160057372A/ko not_active Ceased
- 2016-12-05 US US15/369,281 patent/US20170305967A1/en not_active Abandoned
-
2017
- 2017-01-05 JP JP2017000444A patent/JP6385476B2/ja active Active
- 2017-09-08 KR KR1020170115440A patent/KR101999756B1/ko active Active
-
2018
- 2018-09-24 US US16/140,325 patent/US20190248833A1/en not_active Abandoned
-
2019
- 2019-07-08 KR KR1020190082102A patent/KR20190084025A/ko not_active Ceased
-
2020
- 2020-04-02 US US16/838,290 patent/US11447523B2/en active Active
-
2022
- 2022-08-03 US US17/880,271 patent/US20230212220A1/en not_active Abandoned
-
2025
- 2025-01-15 US US19/022,723 patent/US20250263433A1/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004075856A2 (en) | 2003-02-24 | 2004-09-10 | Novacardia, Inc. | Adenosine a1 receptor antagonist for the treatment of cardiac and renal diseases |
| WO2005055706A1 (ja) | 2003-12-12 | 2005-06-23 | Japan Science And Technology Agency | メグシン/RAGE/iNOS発現疾患モデル動物及び該動物を用いた化合物の評価方法 |
| WO2005072295A2 (en) * | 2004-01-23 | 2005-08-11 | Cornell Research Foundation, Inc. | Methods for reducing oxidative damage |
Non-Patent Citations (1)
| Title |
|---|
| Atherosclerosis. 161(2): 307-316(2002.4.) * |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101999756B1 (ko) | Cd36 발현을 감소시키는 방법 | |
| HK1242610A1 (en) | Methods for reducing cd36 expression | |
| AU2018200395A1 (en) | Methods for reducing cd36 expression | |
| HK1197994B (en) | Methods for reducing cd36 expression | |
| HK1123992B (en) | Methods for reducing cd36 expression | |
| HK1173367B (en) | Methods for reducing cd36 expression |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
|
| AMND | Amendment | ||
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| A201 | Request for examination | ||
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
|
| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
|
| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
|
| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
|
| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
|
| AMND | Amendment | ||
| E13-X000 | Pre-grant limitation requested |
St.27 status event code: A-2-3-E10-E13-lim-X000 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
St.27 status event code: N-2-6-B10-B15-exm-PE0601 |
|
| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
|
| A107 | Divisional application of patent | ||
| AMND | Amendment | ||
| E13-X000 | Pre-grant limitation requested |
St.27 status event code: A-2-3-E10-E13-lim-X000 |
|
| J201 | Request for trial against refusal decision | ||
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| PA0104 | Divisional application for international application |
St.27 status event code: A-0-1-A10-A18-div-PA0104 St.27 status event code: A-0-1-A10-A16-div-PA0104 |
|
| PJ0201 | Trial against decision of rejection |
St.27 status event code: A-3-3-V10-V11-apl-PJ0201 |
|
| PB0901 | Examination by re-examination before a trial |
St.27 status event code: A-6-3-E10-E12-rex-PB0901 |
|
| B701 | Decision to grant | ||
| PB0701 | Decision of registration after re-examination before a trial |
St.27 status event code: A-3-4-F10-F13-rex-PB0701 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
|
| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U12-oth-PR1002 Fee payment year number: 1 |
|
| PG1601 | Publication of registration |
St.27 status event code: A-4-4-Q10-Q13-nap-PG1601 |
|
| FPAY | Annual fee payment |
Payment date: 20170713 Year of fee payment: 4 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 4 |
|
| FPAY | Annual fee payment |
Payment date: 20180713 Year of fee payment: 5 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 5 |
|
| FPAY | Annual fee payment |
Payment date: 20190712 Year of fee payment: 6 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 6 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 7 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 8 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 9 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 10 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 11 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 12 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-OTH-PR1001 (AS PROVIDED BY THE NATIONAL OFFICE) Year of fee payment: 12 |