KR101413616B1 - 트리글리세라이드, 콜레스테롤 및 글루코스 농도를 낮추기 위한 인다졸메톡시알카노산의 용도 - Google Patents

트리글리세라이드, 콜레스테롤 및 글루코스 농도를 낮추기 위한 인다졸메톡시알카노산의 용도 Download PDF

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KR101413616B1
KR101413616B1 KR1020097010871A KR20097010871A KR101413616B1 KR 101413616 B1 KR101413616 B1 KR 101413616B1 KR 1020097010871 A KR1020097010871 A KR 1020097010871A KR 20097010871 A KR20097010871 A KR 20097010871A KR 101413616 B1 KR101413616 B1 KR 101413616B1
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cholesterol
compound
formula
triglyceride
glucose levels
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KR20090081410A (ko
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안젤로 구글리엘모티
쥬세페 비온디
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아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
KR1020097010871A 2006-11-24 2007-11-13 트리글리세라이드, 콜레스테롤 및 글루코스 농도를 낮추기 위한 인다졸메톡시알카노산의 용도 Expired - Fee Related KR101413616B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT002254A ITMI20062254A1 (it) 2006-11-24 2006-11-24 Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
ITMI2006A002254 2006-11-24
PCT/EP2007/009908 WO2008061671A2 (en) 2006-11-24 2007-11-13 Use of an indazolemethoxyalkanoic acid for reducing triglyceride, cholesterol and glucose levels

Publications (2)

Publication Number Publication Date
KR20090081410A KR20090081410A (ko) 2009-07-28
KR101413616B1 true KR101413616B1 (ko) 2014-07-01

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KR1020097010871A Expired - Fee Related KR101413616B1 (ko) 2006-11-24 2007-11-13 트리글리세라이드, 콜레스테롤 및 글루코스 농도를 낮추기 위한 인다졸메톡시알카노산의 용도

Country Status (23)

Country Link
US (2) US8198310B2 (enExample)
EP (2) EP2409698B1 (enExample)
JP (1) JP5192490B2 (enExample)
KR (1) KR101413616B1 (enExample)
CN (1) CN101541323B (enExample)
AR (1) AR063894A1 (enExample)
AU (1) AU2007323351B2 (enExample)
BR (1) BRPI0718522A2 (enExample)
CA (1) CA2666371C (enExample)
CY (1) CY1116664T1 (enExample)
DK (2) DK2097080T3 (enExample)
EA (1) EA016885B1 (enExample)
ES (2) ES2530623T3 (enExample)
GE (1) GEP20125570B (enExample)
IL (1) IL198286A (enExample)
IT (1) ITMI20062254A1 (enExample)
MX (1) MX2009004295A (enExample)
PL (2) PL2097080T3 (enExample)
PT (2) PT2097080E (enExample)
SG (1) SG176508A1 (enExample)
SI (2) SI2409698T1 (enExample)
UA (1) UA97123C2 (enExample)
WO (1) WO2008061671A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20062254A1 (it) 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
CN102471282A (zh) 2009-08-03 2012-05-23 方济各安吉利克化学联合股份有限公司 1-苄基-3-羟甲基-1h-吲唑及其衍生物以及所需镁中间体的制备方法
US8999292B2 (en) 2012-05-01 2015-04-07 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
WO2015173786A1 (en) * 2014-05-15 2015-11-19 Boyd Shelley Romayne Compositions and methods for treating and diagnosing ocular disorders
CA3144861A1 (en) 2019-06-25 2020-12-30 Translatum Medicus, Inc. Processes of making 2-((1-benzyl-1h-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives
WO2021263246A1 (en) 2020-06-27 2021-12-30 Crescenta Biosciences Novel cell metabolism modulating compounds and uses thereof
US12138243B2 (en) 2021-12-31 2024-11-12 Crescenta Biosciences Antiviral use of FABP4 modulating compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6534534B1 (en) * 1997-07-28 2003-03-18 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Pharmaceutical composition active in reducing production of MCP-1 protein

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1131779B (it) * 1980-07-29 1986-06-25 Acraf Sale dell'acido (1-benzil-1h-indazol-3-il)-ossiacetico con la lisina e procedimento per la sua preparazione
IT1230441B (it) * 1989-02-07 1991-10-23 Acraf Eteri della serie dell'indazolo
IT1253703B (it) 1991-04-22 1995-08-23 Angelini Francesco Ist Ricerca Uso di acidi metossi alcanoici dell'indazolo per preparare un farmaco attivo nel trattamento di malattie autoimmunitarie
IT1276031B1 (it) * 1995-10-31 1997-10-24 Angelini Ricerche Spa Composizione farmaceutica per il trattamento delle malattie autoimmuni
US6077539A (en) * 1996-11-12 2000-06-20 Pozen, Inc. Treatment of migraine headache
IT1293794B1 (it) 1997-07-28 1999-03-10 Acraf Farmaco attivo nel ridurre la produzione di proteina mcp-1
AU766219B2 (en) * 1998-02-02 2003-10-09 1149336 Ontario Inc. Method of regulating glucose metabolism, and reagents related thereto
DE19821625C1 (de) * 1998-05-15 2000-01-05 Merck Patent Gmbh Pharmazeutische Zubereitung
US6197786B1 (en) * 1998-09-17 2001-03-06 Pfizer Inc 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
ITFI20010230A1 (it) * 2001-11-29 2003-05-29 Menarini Int Operations Lu Sa Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii
US20060030582A1 (en) * 2002-04-29 2006-02-09 Demartino Julie Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity
CA2605900A1 (en) 2005-04-29 2006-11-09 Nycomed Gmbh Mutual prodrug compounds for use as antiinflammatory agents with gastrointestinal protective activity
JP5368801B2 (ja) * 2005-12-01 2013-12-18 フリンダーズ パートナーズ ピーティワイ リミテッド 膵炎を予防および／または治療するための方法および組成物
ITMI20062254A1 (it) 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6534534B1 (en) * 1997-07-28 2003-03-18 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Pharmaceutical composition active in reducing production of MCP-1 protein

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Publication number Publication date
EP2097080A2 (en) 2009-09-09
EP2409698A1 (en) 2012-01-25
PT2409698E (pt) 2015-02-10
AR063894A1 (es) 2009-02-25
SI2409698T1 (sl) 2015-04-30
SI2097080T1 (sl) 2013-05-31
SG176508A1 (en) 2011-12-29
ES2403584T3 (es) 2013-05-20
IL198286A (en) 2016-03-31
HK1165275A1 (en) 2012-10-05
IL198286A0 (en) 2010-02-17
GEP20125570B (en) 2012-07-10
CY1116664T1 (el) 2017-03-15
WO2008061671A3 (en) 2008-11-27
EP2097080B1 (en) 2013-02-20
WO2008061671A2 (en) 2008-05-29
HK1129071A1 (en) 2009-11-20
US20100069456A1 (en) 2010-03-18
JP2010510263A (ja) 2010-04-02
CA2666371A1 (en) 2008-05-29
US8846745B2 (en) 2014-09-30
US20120283307A1 (en) 2012-11-08
MX2009004295A (es) 2009-05-05
ES2530623T3 (es) 2015-03-04
CN101541323B (zh) 2012-01-04
EA200970506A1 (ru) 2009-10-30
PL2097080T3 (pl) 2013-07-31
PL2409698T3 (pl) 2015-06-30
AU2007323351B2 (en) 2013-05-02
DK2409698T3 (en) 2015-04-27
EP2409698B1 (en) 2015-01-21
CN101541323A (zh) 2009-09-23
AU2007323351A1 (en) 2008-05-29
CA2666371C (en) 2014-05-06
US8198310B2 (en) 2012-06-12
UA97123C2 (uk) 2012-01-10
DK2097080T3 (da) 2013-05-21
JP5192490B2 (ja) 2013-05-08
BRPI0718522A2 (pt) 2013-11-12
EA016885B1 (ru) 2012-08-30
ITMI20062254A1 (it) 2008-05-25
KR20090081410A (ko) 2009-07-28
PT2097080E (pt) 2013-04-01

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