GEP20125570B - Use of indazolemethoxyalkanoic acid for reducing levels of triglycerides, cholesterol and glucose - Google Patents
Use of indazolemethoxyalkanoic acid for reducing levels of triglycerides, cholesterol and glucoseInfo
- Publication number
- GEP20125570B GEP20125570B GEAP200711327A GEAP2007011327A GEP20125570B GE P20125570 B GEP20125570 B GE P20125570B GE AP200711327 A GEAP200711327 A GE AP200711327A GE AP2007011327 A GEAP2007011327 A GE AP2007011327A GE P20125570 B GEP20125570 B GE P20125570B
- Authority
- GE
- Georgia
- Prior art keywords
- cholesterol
- glucose
- triglycerides
- reducing levels
- indazolemethoxyalkanoic
- Prior art date
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title abstract 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 title abstract 2
- 235000012000 cholesterol Nutrition 0.000 title abstract 2
- 239000008103 glucose Substances 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 150000003626 triacylglycerols Chemical class 0.000 title 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Mixers Of The Rotary Stirring Type (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT002254A ITMI20062254A1 (it) | 2006-11-24 | 2006-11-24 | Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GEP20125570B true GEP20125570B (en) | 2012-07-10 |
Family
ID=38198404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GEAP200711327A GEP20125570B (en) | 2006-11-24 | 2007-11-13 | Use of indazolemethoxyalkanoic acid for reducing levels of triglycerides, cholesterol and glucose |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US8198310B2 (enExample) |
| EP (2) | EP2409698B1 (enExample) |
| JP (1) | JP5192490B2 (enExample) |
| KR (1) | KR101413616B1 (enExample) |
| CN (1) | CN101541323B (enExample) |
| AR (1) | AR063894A1 (enExample) |
| AU (1) | AU2007323351B2 (enExample) |
| BR (1) | BRPI0718522A2 (enExample) |
| CA (1) | CA2666371C (enExample) |
| CY (1) | CY1116664T1 (enExample) |
| DK (2) | DK2097080T3 (enExample) |
| EA (1) | EA016885B1 (enExample) |
| ES (2) | ES2530623T3 (enExample) |
| GE (1) | GEP20125570B (enExample) |
| IL (1) | IL198286A (enExample) |
| IT (1) | ITMI20062254A1 (enExample) |
| MX (1) | MX2009004295A (enExample) |
| PL (2) | PL2097080T3 (enExample) |
| PT (2) | PT2097080E (enExample) |
| SG (1) | SG176508A1 (enExample) |
| SI (2) | SI2409698T1 (enExample) |
| UA (1) | UA97123C2 (enExample) |
| WO (1) | WO2008061671A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20062254A1 (it) | 2006-11-24 | 2008-05-25 | Acraf | Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca |
| CN102471282A (zh) | 2009-08-03 | 2012-05-23 | 方济各安吉利克化学联合股份有限公司 | 1-苄基-3-羟甲基-1h-吲唑及其衍生物以及所需镁中间体的制备方法 |
| US8999292B2 (en) | 2012-05-01 | 2015-04-07 | Translatum Medicus Inc. | Methods for treating and diagnosing blinding eye diseases |
| WO2015173786A1 (en) * | 2014-05-15 | 2015-11-19 | Boyd Shelley Romayne | Compositions and methods for treating and diagnosing ocular disorders |
| CA3144861A1 (en) | 2019-06-25 | 2020-12-30 | Translatum Medicus, Inc. | Processes of making 2-((1-benzyl-1h-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives |
| WO2021263246A1 (en) | 2020-06-27 | 2021-12-30 | Crescenta Biosciences | Novel cell metabolism modulating compounds and uses thereof |
| US12138243B2 (en) | 2021-12-31 | 2024-11-12 | Crescenta Biosciences | Antiviral use of FABP4 modulating compounds |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1131779B (it) * | 1980-07-29 | 1986-06-25 | Acraf | Sale dell'acido (1-benzil-1h-indazol-3-il)-ossiacetico con la lisina e procedimento per la sua preparazione |
| IT1230441B (it) * | 1989-02-07 | 1991-10-23 | Acraf | Eteri della serie dell'indazolo |
| IT1253703B (it) | 1991-04-22 | 1995-08-23 | Angelini Francesco Ist Ricerca | Uso di acidi metossi alcanoici dell'indazolo per preparare un farmaco attivo nel trattamento di malattie autoimmunitarie |
| IT1276031B1 (it) * | 1995-10-31 | 1997-10-24 | Angelini Ricerche Spa | Composizione farmaceutica per il trattamento delle malattie autoimmuni |
| US6077539A (en) * | 1996-11-12 | 2000-06-20 | Pozen, Inc. | Treatment of migraine headache |
| IT1293795B1 (it) * | 1997-07-28 | 1999-03-10 | Angelini Ricerche Spa | Farmaco attivo nel ridurre la produzione di proteina mcp-1 |
| IT1293794B1 (it) | 1997-07-28 | 1999-03-10 | Acraf | Farmaco attivo nel ridurre la produzione di proteina mcp-1 |
| AU766219B2 (en) * | 1998-02-02 | 2003-10-09 | 1149336 Ontario Inc. | Method of regulating glucose metabolism, and reagents related thereto |
| DE19821625C1 (de) * | 1998-05-15 | 2000-01-05 | Merck Patent Gmbh | Pharmazeutische Zubereitung |
| US6197786B1 (en) * | 1998-09-17 | 2001-03-06 | Pfizer Inc | 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines |
| ITFI20010230A1 (it) * | 2001-11-29 | 2003-05-29 | Menarini Int Operations Lu Sa | Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii |
| US20060030582A1 (en) * | 2002-04-29 | 2006-02-09 | Demartino Julie | Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity |
| CA2605900A1 (en) | 2005-04-29 | 2006-11-09 | Nycomed Gmbh | Mutual prodrug compounds for use as antiinflammatory agents with gastrointestinal protective activity |
| JP5368801B2 (ja) * | 2005-12-01 | 2013-12-18 | フリンダーズ パートナーズ ピーティワイ リミテッド | 膵炎を予防および／または治療するための方法および組成物 |
| ITMI20062254A1 (it) | 2006-11-24 | 2008-05-25 | Acraf | Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca |
-
2006
- 2006-11-24 IT IT002254A patent/ITMI20062254A1/it unknown
-
2007
- 2007-11-13 SG SG2011086337A patent/SG176508A1/en unknown
- 2007-11-13 BR BRPI0718522-7A patent/BRPI0718522A2/pt active Search and Examination
- 2007-11-13 ES ES11185914T patent/ES2530623T3/es active Active
- 2007-11-13 JP JP2009537517A patent/JP5192490B2/ja not_active Expired - Fee Related
- 2007-11-13 PL PL07819835T patent/PL2097080T3/pl unknown
- 2007-11-13 SI SI200731621T patent/SI2409698T1/sl unknown
- 2007-11-13 EA EA200970506A patent/EA016885B1/ru not_active IP Right Cessation
- 2007-11-13 CN CN2007800432200A patent/CN101541323B/zh not_active Expired - Fee Related
- 2007-11-13 DK DK07819835.5T patent/DK2097080T3/da active
- 2007-11-13 PL PL11185914T patent/PL2409698T3/pl unknown
- 2007-11-13 GE GEAP200711327A patent/GEP20125570B/en unknown
- 2007-11-13 MX MX2009004295A patent/MX2009004295A/es active IP Right Grant
- 2007-11-13 AU AU2007323351A patent/AU2007323351B2/en not_active Ceased
- 2007-11-13 WO PCT/EP2007/009908 patent/WO2008061671A2/en not_active Ceased
- 2007-11-13 ES ES07819835T patent/ES2403584T3/es active Active
- 2007-11-13 EP EP11185914.6A patent/EP2409698B1/en not_active Not-in-force
- 2007-11-13 EP EP07819835A patent/EP2097080B1/en not_active Not-in-force
- 2007-11-13 SI SI200731208T patent/SI2097080T1/sl unknown
- 2007-11-13 UA UAA200905093A patent/UA97123C2/uk unknown
- 2007-11-13 CA CA2666371A patent/CA2666371C/en not_active Expired - Fee Related
- 2007-11-13 PT PT78198355T patent/PT2097080E/pt unknown
- 2007-11-13 US US12/444,442 patent/US8198310B2/en not_active Expired - Fee Related
- 2007-11-13 DK DK11185914T patent/DK2409698T3/en active
- 2007-11-13 PT PT111859146T patent/PT2409698E/pt unknown
- 2007-11-13 KR KR1020097010871A patent/KR101413616B1/ko not_active Expired - Fee Related
- 2007-11-22 AR ARP070105182A patent/AR063894A1/es not_active Application Discontinuation
-
2009
- 2009-04-22 IL IL198286A patent/IL198286A/en active IP Right Grant
-
2012
- 2012-05-08 US US13/466,503 patent/US8846745B2/en not_active Expired - Fee Related
-
2015
- 2015-02-20 CY CY20151100184T patent/CY1116664T1/el unknown
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