KR101325519B1 - 도파민 ｄ3 수용체의 조절에 반응하는 장애를 치료하기에적합한 아릴설포닐메틸 또는 아릴설폰아미드 치환된 방향족화합물 - Google Patents

도파민 ｄ3 수용체의 조절에 반응하는 장애를 치료하기에적합한 아릴설포닐메틸 또는 아릴설폰아미드 치환된 방향족화합물 Download PDF

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KR101325519B1
KR101325519B1 KR1020077010954A KR20077010954A KR101325519B1 KR 101325519 B1 KR101325519 B1 KR 101325519B1 KR 1020077010954 A KR1020077010954 A KR 1020077010954A KR 20077010954 A KR20077010954 A KR 20077010954A KR 101325519 B1 KR101325519 B1 KR 101325519B1
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tetrahydro
naphthalen
benzenesulfonamide
propylamino
alkyl
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KR20070084207A (ko
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카를라 드레셔
안드레아스 하웁트
릴리아네 운거
신 씨 터너
빌프리트 브라예
롤란트 그란델
크리스토프 앙리
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애보트 게엠베하 운트 콤파니 카게
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    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
    • C07C311/44—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
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    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
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KR1020077010954A 2004-10-14 2005-10-14 도파민 ｄ3 수용체의 조절에 반응하는 장애를 치료하기에적합한 아릴설포닐메틸 또는 아릴설폰아미드 치환된 방향족화합물 Expired - Fee Related KR101325519B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US61877604P 2004-10-14 2004-10-14
US60/618,776 2004-10-14
US71194205P 2005-08-26 2005-08-26
US60/711,942 2005-08-26
PCT/EP2005/011091 WO2006040178A1 (en) 2004-10-14 2005-10-14 Arylsulfonylmethyl or arylsulfonamide substituted aromatic compounds suitable for treating disorders that respond to madulation of the dopamine d3 receptor

Related Child Applications (1)

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KR1020137005570A Division KR20130028988A (ko) 2004-10-14 2005-10-14 도파민 ｄ3 수용체의 조절에 반응하는 장애를 치료하기에 적합한 아릴설포닐메틸 또는 아릴설폰아미드 치환된 방향족 화합물

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KR20070084207A KR20070084207A (ko) 2007-08-24
KR101325519B1 true KR101325519B1 (ko) 2013-11-08

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KR1020077010954A Expired - Fee Related KR101325519B1 (ko) 2004-10-14 2005-10-14 도파민 ｄ3 수용체의 조절에 반응하는 장애를 치료하기에적합한 아릴설포닐메틸 또는 아릴설폰아미드 치환된 방향족화합물
KR1020137005570A Withdrawn KR20130028988A (ko) 2004-10-14 2005-10-14 도파민 ｄ3 수용체의 조절에 반응하는 장애를 치료하기에 적합한 아릴설포닐메틸 또는 아릴설폰아미드 치환된 방향족 화합물

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KR1020137005570A Withdrawn KR20130028988A (ko) 2004-10-14 2005-10-14 도파민 ｄ3 수용체의 조절에 반응하는 장애를 치료하기에 적합한 아릴설포닐메틸 또는 아릴설폰아미드 치환된 방향족 화합물

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US (1) US8969552B2 (https=)
EP (2) EP1812416B1 (https=)
JP (1) JP5193602B2 (https=)
KR (2) KR101325519B1 (https=)
CN (2) CN103073460B (https=)
AU (1) AU2005293694B2 (https=)
BR (1) BRPI0516115A (https=)
CA (1) CA2583779C (https=)
CR (2) CR9057A (https=)
EC (1) ECSP077394A (https=)
ES (2) ES2529720T3 (https=)
IL (2) IL182429A (https=)
MA (1) MA28952B1 (https=)
MX (1) MX2007004356A (https=)
NO (1) NO20072418L (https=)
NZ (2) NZ555124A (https=)
RU (1) RU2442781C2 (https=)
TW (1) TWI361806B (https=)
WO (1) WO2006040178A1 (https=)
ZA (1) ZA200703060B (https=)

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AR054363A1 (es) * 2005-05-23 2007-06-20 Astrazeneca Ab Compuestos que exhiben actividad moduladora en el receptor 5-hidroxi-triptamina 6
TW200927740A (en) * 2007-11-13 2009-07-01 Bial Portela & Ca Sa Process
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