KR101265343B1 - Ｓｅｃ-시스템 분비에 의한 개선된 발현 시스템 - Google Patents

Ｓｅｃ-시스템 분비에 의한 개선된 발현 시스템 Download PDF

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KR101265343B1
KR101265343B1 KR1020067009779A KR20067009779A KR101265343B1 KR 101265343 B1 KR101265343 B1 KR 101265343B1 KR 1020067009779 A KR1020067009779 A KR 1020067009779A KR 20067009779 A KR20067009779 A KR 20067009779A KR 101265343 B1 KR101265343 B1 KR 101265343B1
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peptide
protein
sequence
recombinant
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KR20060123173A (ko
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다이앤 엠. 레탈락
제인 시. 슈나이더
토마스 마틴 람세이에
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다우 글로벌 테크놀로지스 엘엘씨
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Assigned to 피페넥스 인크. reassignment 피페넥스 인크. 권리의 전부이전등록 Assignors: 다우 글로벌 테크놀로지스 엘엘씨
Assigned to 펠리칸 테크놀로지 홀딩스, 인크. reassignment 펠리칸 테크놀로지 홀딩스, 인크. 권리의 전부이전등록 Assignors: 피페넥스 인크.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/16—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
KR1020067009779A 2003-11-21 2006-05-19 Ｓｅｃ-시스템 분비에 의한 개선된 발현 시스템 Expired - Lifetime KR101265343B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52412403P 2003-11-21 2003-11-21
US60/524,124 2003-11-21
PCT/US2004/039316 WO2005089093A2 (en) 2003-11-21 2004-11-22 Improved expression systems with sec-system secretion

Publications (2)

Publication Number Publication Date
KR20060123173A KR20060123173A (ko) 2006-12-01
KR101265343B1 true KR101265343B1 (ko) 2013-05-20

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US (1) US7985564B2 (https=)
EP (4) EP1687324B1 (https=)
JP (1) JP5028551B2 (https=)
KR (1) KR101265343B1 (https=)
CN (1) CN1882605B (https=)
AU (1) AU2004317306B2 (https=)
BR (1) BRPI0416807A (https=)
CA (1) CA2546157C (https=)
MX (1) MXPA06005705A (https=)
PL (2) PL2336153T3 (https=)
WO (1) WO2005089093A2 (https=)

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JP2017521055A (ja) 2014-06-20 2017-08-03 ダウ アグロサイエンシィズ エルエルシー 害虫防除に有用な植物性殺虫タンパク質
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EP2327718B1 (en) 2016-03-23
WO2005089093A3 (en) 2006-03-02
EP2336153B1 (en) 2016-03-30
AU2004317306A1 (en) 2005-09-29
EP1687324B1 (en) 2012-08-22
JP5028551B2 (ja) 2012-09-19
CA2546157A1 (en) 2005-09-29
CA2546157C (en) 2014-07-22
PL2327718T3 (pl) 2016-10-31
EP1687324A2 (en) 2006-08-09
CN1882605A (zh) 2006-12-20
BRPI0416807A (pt) 2007-01-09
CN1882605B (zh) 2012-07-11
EP1687324A4 (en) 2007-08-22
AU2004317306B2 (en) 2010-09-02
JP2007512028A (ja) 2007-05-17
EP2327718A1 (en) 2011-06-01
US7985564B2 (en) 2011-07-26
WO2005089093A2 (en) 2005-09-29
KR20060123173A (ko) 2006-12-01
EP2336153A1 (en) 2011-06-22
EP2314602A1 (en) 2011-04-27
MXPA06005705A (es) 2006-08-23
PL2336153T3 (pl) 2016-08-31
US20060008877A1 (en) 2006-01-12

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