PL2336153T3 - Udoskonalone systemy ekspresji z układem wydzielania SEC - Google Patents
Udoskonalone systemy ekspresji z układem wydzielania SECInfo
- Publication number
- PL2336153T3 PL2336153T3 PL10179651T PL10179651T PL2336153T3 PL 2336153 T3 PL2336153 T3 PL 2336153T3 PL 10179651 T PL10179651 T PL 10179651T PL 10179651 T PL10179651 T PL 10179651T PL 2336153 T3 PL2336153 T3 PL 2336153T3
- Authority
- PL
- Poland
- Prior art keywords
- sec
- expression systems
- improved expression
- system secretion
- secretion
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormones [GH] (Somatotropin)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/16—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52412403P | 2003-11-21 | 2003-11-21 | |
| EP04817876A EP1687324B1 (en) | 2003-11-21 | 2004-11-22 | Improved expression systems with sec-system secretion |
| EP10179651.4A EP2336153B1 (en) | 2003-11-21 | 2004-11-22 | Improved expression systems with SEC-system secretion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2336153T3 true PL2336153T3 (pl) | 2016-08-31 |
Family
ID=34994140
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10179615.9T PL2327718T3 (pl) | 2003-11-21 | 2004-11-22 | Ulepszone systemy ekspresyjne z wykorzystaniem systemu sekrecji SEC |
| PL10179651T PL2336153T3 (pl) | 2003-11-21 | 2004-11-22 | Udoskonalone systemy ekspresji z układem wydzielania SEC |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10179615.9T PL2327718T3 (pl) | 2003-11-21 | 2004-11-22 | Ulepszone systemy ekspresyjne z wykorzystaniem systemu sekrecji SEC |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7985564B2 (pl) |
| EP (4) | EP2336153B1 (pl) |
| JP (1) | JP5028551B2 (pl) |
| KR (1) | KR101265343B1 (pl) |
| CN (1) | CN1882605B (pl) |
| AU (1) | AU2004317306B2 (pl) |
| BR (1) | BRPI0416807A (pl) |
| CA (1) | CA2546157C (pl) |
| MX (1) | MXPA06005705A (pl) |
| PL (2) | PL2327718T3 (pl) |
| WO (1) | WO2005089093A2 (pl) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9453251B2 (en) * | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
| EP2336153B1 (en) | 2003-11-21 | 2016-03-30 | Pfenex Inc. | Improved expression systems with SEC-system secretion |
| JP2008507294A (ja) | 2004-07-26 | 2008-03-13 | ダウ グローバル テクノロジーズ インコーポレイティド | 菌株遺伝子操作による改善されたタンパク質発現のための方法 |
| JP5130662B2 (ja) * | 2006-06-07 | 2013-01-30 | Ｊｎｃ株式会社 | タンパク質の可溶性タンパク質としての製造方法 |
| EP2468869B1 (en) * | 2007-01-31 | 2015-03-18 | Pfenex Inc. | Bacterial leader sequences for increased expression |
| BRPI0810120A2 (pt) | 2007-04-27 | 2014-11-11 | Dow Global Technologies Inc | Processo para selecionar rapidamente hospedeiros microbianos para a identificação de certas cepas com maior rendimento e/ou qualidade na expressão de proteínas heterólogas |
| US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| WO2009076196A1 (en) | 2007-12-07 | 2009-06-18 | Dow Global Technologies Inc. | High copy number self-replicating plasmids in pseudomonas |
| WO2010008764A1 (en) * | 2008-06-23 | 2010-01-21 | Dow Global Technologies Inc. | Pseudomonas fluorescens strains for production of extracellular recombinant protein |
| BRPI1015333A2 (pt) | 2009-04-17 | 2016-05-24 | Dow Agrosciences Llc | "toxinas cry inseticidas dig-3" |
| ES2663283T3 (es) | 2009-12-16 | 2018-04-11 | Dow Agrosciences Llc | Uso combinado de las proteínas CRY1Ca y CRY1Fa para el control de insectos resistentes |
| CA2791361C (en) | 2010-03-04 | 2018-06-12 | Pfenex Inc. | Method for producing soluble recombinant interferon protein without denaturing |
| EP2553102B1 (en) | 2010-03-30 | 2015-12-09 | Pfenex Inc. | High level expression of recombinant toxin proteins |
| EP2552949B1 (en) | 2010-04-01 | 2016-08-17 | Pfenex Inc. | Methods for g-csf production in a pseudomonas host cell |
| NZ603561A (en) | 2010-04-23 | 2015-06-26 | Dow Agrosciences Llc | Combinations including cry34ab/35ab and cry3aa proteins to prevent development of resistance in corn rootworms (diabrotica spp.) |
| US9234208B1 (en) | 2010-05-10 | 2016-01-12 | Dow Agrosciences Llc | DIG-13 insecticidal cry toxins |
| AR084293A1 (es) | 2010-12-16 | 2013-05-08 | Dow Agrosciences Llc | Cry1FA RADIOMARCADA, BIOLOGICAMENTE ACTIVA Y METODOS DE ENSAYOS DE UNION AL RECEPTOR |
| EP2841590A4 (en) * | 2012-04-27 | 2016-03-23 | Pronutria Inc | NUCLEIC ACIDS, CELLS AND METHODS FOR PRODUCING SECRETED PROTEINS |
| US9169304B2 (en) | 2012-05-01 | 2015-10-27 | Pfenex Inc. | Process for purifying recombinant Plasmodium falciparum circumsporozoite protein |
| CN103254277B (zh) * | 2013-05-03 | 2017-02-08 | 南京工业大学 | 强分泌性信号肽增强小肽模序及其应用 |
| TW201542093A (zh) | 2014-03-21 | 2015-11-16 | 艾格里遺傳學股份有限公司 | 用於控制玉米穗蟲之Ｃｒｙ１Ｄ |
| NZ726117A (en) | 2014-06-20 | 2017-10-27 | Dow Agrosciences Llc | Vegetative insecticidal proteins useful for control of insect pests |
| SG11201704362VA (en) | 2014-12-01 | 2017-06-29 | Pfenex Inc | Fusion partners for peptide production |
| RU2017122359A (ru) | 2014-12-30 | 2019-01-31 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Модифицированные токсины cryca, применимые для борьбы с насекомыми-вредителями |
| MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
| US10889830B2 (en) | 2016-09-30 | 2021-01-12 | Dow Agrosciences Llc | Binary insecticidal Cry toxins |
| SG11201909931PA (en) | 2017-04-27 | 2019-11-28 | Juno Therapeutics Gmbh | Oligomeric particle reagents and methods of use thereof |
| AU2018354069A1 (en) * | 2017-10-27 | 2020-06-11 | Pelican Technology Holdings, Inc. | Bacterial leader sequences for periplasmic protein expression |
| JP2021500896A (ja) | 2017-10-27 | 2021-01-14 | フェネックス インク． | 組み換えｅｒｗｉｎｉａアスパラギナーゼの製造のための方法 |
| CN113528574B (zh) * | 2018-08-07 | 2022-06-21 | 康码（上海）生物科技有限公司 | 信号肽相关序列及其在蛋白质合成中的应用 |
| CN112812176B (zh) * | 2021-01-13 | 2022-10-11 | 江南大学 | 一种通过低盐絮凝法从螺旋藻中提取藻蓝蛋白的方法 |
| WO2022211829A1 (en) | 2021-03-30 | 2022-10-06 | Jazz Pharmaceuticals Ireland Ltd. | Dosing of recombinant l-asparaginase |
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| WO2004005221A2 (en) | 2002-07-03 | 2004-01-15 | Dow Global Technologies Inc | Benzoate- and anthranilate-inducible promoters |
| EP2336153B1 (en) | 2003-11-21 | 2016-03-30 | Pfenex Inc. | Improved expression systems with SEC-system secretion |
| ES2663594T3 (es) | 2004-01-16 | 2018-04-16 | Pfenex Inc | Expresión de proteínas de mamífero en Pseudomonas fluorescens |
| EP2468869B1 (en) * | 2007-01-31 | 2015-03-18 | Pfenex Inc. | Bacterial leader sequences for increased expression |
-
2004
- 2004-11-22 EP EP10179651.4A patent/EP2336153B1/en active Active
- 2004-11-22 EP EP04817876A patent/EP1687324B1/en active Active
- 2004-11-22 PL PL10179615.9T patent/PL2327718T3/pl unknown
- 2004-11-22 PL PL10179651T patent/PL2336153T3/pl unknown
- 2004-11-22 WO PCT/US2004/039316 patent/WO2005089093A2/en not_active Application Discontinuation
- 2004-11-22 EP EP10179615.9A patent/EP2327718B1/en active Active
- 2004-11-22 US US10/996,007 patent/US7985564B2/en active Active
- 2004-11-22 MX MXPA06005705A patent/MXPA06005705A/es active IP Right Grant
- 2004-11-22 AU AU2004317306A patent/AU2004317306B2/en active Active
- 2004-11-22 EP EP10179657A patent/EP2314602A1/en not_active Withdrawn
- 2004-11-22 CA CA2546157A patent/CA2546157C/en active Active
- 2004-11-22 JP JP2006541651A patent/JP5028551B2/ja active Active
- 2004-11-22 BR BRPI0416807-0A patent/BRPI0416807A/pt not_active IP Right Cessation
- 2004-11-22 CN CN200480034455XA patent/CN1882605B/zh not_active Expired - Fee Related
-
2006
- 2006-05-19 KR KR1020067009779A patent/KR101265343B1/ko active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP2336153B1 (en) | 2016-03-30 |
| JP2007512028A (ja) | 2007-05-17 |
| WO2005089093A2 (en) | 2005-09-29 |
| EP2327718A1 (en) | 2011-06-01 |
| US20060008877A1 (en) | 2006-01-12 |
| KR20060123173A (ko) | 2006-12-01 |
| CN1882605A (zh) | 2006-12-20 |
| EP1687324A2 (en) | 2006-08-09 |
| AU2004317306A1 (en) | 2005-09-29 |
| BRPI0416807A (pt) | 2007-01-09 |
| WO2005089093A3 (en) | 2006-03-02 |
| US7985564B2 (en) | 2011-07-26 |
| CA2546157C (en) | 2014-07-22 |
| JP5028551B2 (ja) | 2012-09-19 |
| EP2327718B1 (en) | 2016-03-23 |
| EP2314602A1 (en) | 2011-04-27 |
| MXPA06005705A (es) | 2006-08-23 |
| EP2336153A1 (en) | 2011-06-22 |
| EP1687324B1 (en) | 2012-08-22 |
| CN1882605B (zh) | 2012-07-11 |
| KR101265343B1 (ko) | 2013-05-20 |
| CA2546157A1 (en) | 2005-09-29 |
| EP1687324A4 (en) | 2007-08-22 |
| PL2327718T3 (pl) | 2016-10-31 |
| AU2004317306B2 (en) | 2010-09-02 |
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