KR101265180B1 - 아이지에프비피-2 및 아이지에프비피-5를 억제하는 양특이성 안티센스 올리고뉴클레오티드, 이를 이용하여 약학적 조성물을 제조하는 방법 및 그 약학적 조성물 - Google Patents

아이지에프비피-2 및 아이지에프비피-5를 억제하는 양특이성 안티센스 올리고뉴클레오티드, 이를 이용하여 약학적 조성물을 제조하는 방법 및 그 약학적 조성물 Download PDF

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KR101265180B1
KR101265180B1 KR1020047011085A KR20047011085A KR101265180B1 KR 101265180 B1 KR101265180 B1 KR 101265180B1 KR 1020047011085 A KR1020047011085 A KR 1020047011085A KR 20047011085 A KR20047011085 A KR 20047011085A KR 101265180 B1 KR101265180 B1 KR 101265180B1
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igfbp
antisense oligonucleotide
seq
sequence
antisense
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KR20040085150A (ko
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글리브마틴
시냐프스키막심
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더 유니버시티 오브 브리티쉬 콜롬비아
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/51—Physical structure in polymeric form, e.g. multimers, concatemers

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KR1020047011085A 2002-01-17 2003-01-17 아이지에프비피-2 및 아이지에프비피-5를 억제하는 양특이성 안티센스 올리고뉴클레오티드, 이를 이용하여 약학적 조성물을 제조하는 방법 및 그 약학적 조성물 Expired - Fee Related KR101265180B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35004602P 2002-01-17 2002-01-17
US60/350,046 2002-01-17
PCT/CA2003/000061 WO2003062421A1 (en) 2002-01-17 2003-01-17 Bispecific antisense olignucleotides that inhibit igfbp-2 and igfbp-5 and methods of using same

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KR1020117003991A Division KR101166214B1 (ko) 2002-01-17 2003-01-17 아이지에프비피-2 및 아이지에프비피-5를 억제하는 양특이성 안티센스 올리고뉴클레오티드 및 그 사용방법

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KR20040085150A KR20040085150A (ko) 2004-10-07
KR101265180B1 true KR101265180B1 (ko) 2013-05-29

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KR1020047011085A Expired - Fee Related KR101265180B1 (ko) 2002-01-17 2003-01-17 아이지에프비피-2 및 아이지에프비피-5를 억제하는 양특이성 안티센스 올리고뉴클레오티드, 이를 이용하여 약학적 조성물을 제조하는 방법 및 그 약학적 조성물
KR1020117003991A Expired - Fee Related KR101166214B1 (ko) 2002-01-17 2003-01-17 아이지에프비피-2 및 아이지에프비피-5를 억제하는 양특이성 안티센스 올리고뉴클레오티드 및 그 사용방법

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US (11) US20030158143A1 (enExample)
EP (1) EP1465995B1 (enExample)
JP (1) JP4491240B2 (enExample)
KR (2) KR101265180B1 (enExample)
AT (1) ATE402999T1 (enExample)
AU (1) AU2003237616B2 (enExample)
CA (1) CA2469685C (enExample)
DE (1) DE60322509D1 (enExample)
DK (1) DK1465995T3 (enExample)
ES (1) ES2307942T3 (enExample)
HU (1) HU229452B1 (enExample)
IL (2) IL162540A0 (enExample)
NO (1) NO333017B1 (enExample)
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US7928082B2 (en) 2011-04-19
US8541390B2 (en) 2013-09-24
US8252765B2 (en) 2012-08-28
US20110196019A1 (en) 2011-08-11
NZ533126A (en) 2006-04-28
DE60322509D1 (de) 2008-09-11
HU229452B1 (en) 2013-12-30
IL162540A (en) 2011-06-30
US20130096180A1 (en) 2013-04-18
NO333017B1 (no) 2013-02-18
CA2469685C (en) 2013-03-12
NO20043401L (no) 2004-10-13
ATE402999T1 (de) 2008-08-15
HUP0402543A3 (en) 2012-09-28
US20030158143A1 (en) 2003-08-21
IL162540A0 (en) 2005-11-20
US9101646B2 (en) 2015-08-11
AU2003237616B2 (en) 2007-07-05
US20120220646A1 (en) 2012-08-30
US8835401B2 (en) 2014-09-16
DK1465995T3 (da) 2008-10-20
US8470796B2 (en) 2013-06-25
CA2469685A1 (en) 2003-07-31
US8580761B2 (en) 2013-11-12
US20160002630A1 (en) 2016-01-07
WO2003062421A1 (en) 2003-07-31
EP1465995B1 (en) 2008-07-30
ES2307942T3 (es) 2008-12-01
US20060122141A1 (en) 2006-06-08
US20080261912A1 (en) 2008-10-23
US7973017B2 (en) 2011-07-05
US20100267808A1 (en) 2010-10-21
EP1465995A1 (en) 2004-10-13
JP4491240B2 (ja) 2010-06-30
KR101166214B1 (ko) 2012-07-16
JP2005514948A (ja) 2005-05-26
KR20040085150A (ko) 2004-10-07
US20110190382A1 (en) 2011-08-04
US20120077861A1 (en) 2012-03-29
KR20110026023A (ko) 2011-03-14
US8389491B2 (en) 2013-03-05
HUP0402543A2 (hu) 2005-03-29
US20130303592A1 (en) 2013-11-14

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