KR101239516B1 - Cosmetic composition comprising the herbal extract comprising Arterisia argyi LEVL. et VANT. for preventing hair activity - Google Patents

Abstract

The present invention relates to a composition having a hair surface protection effect and an increase in tensile strength by hydrogen peroxide water, and more particularly, a composition containing an herbal extract of a larva as an active ingredient shows a hair protection effect through a simple clinical experiment. It can be usefully used as a cosmetic composition that exhibits the effect of inhibiting hair damage by increasing hydrogen peroxide, increasing tensile strength and protecting the scalp.

Description

Hair protection cosmetic composition containing a leaf extract as an active ingredient {Cosmetic composition comprising the herbal extract comprising Arterisia argyi LEVL. et VANT. for preventing hair activity}

The present invention relates to a cosmetic composition having a hair surface protection effect and tensile strength increasing effect containing the leaf extract as an active ingredient.

[Patent 1] Publication 10-2002-0041048

[Patent 2] Publication 10-2007-0020969

[Patent 3] Publication 10-2002-0045127

[Patent 4] Publication 10-2007-0056597

[Patent 5] Publication 10-2000-0014138

[Patent 6] Publication 10-1999-0032659

[Patent 7] Publication 10-2006-0021965

[Patent 8] Publication 10-2001-0082716

[Patent 9] Publication 10-2000-0060181

[Patent Document 10] Publication 10-2005-0097502

[Document 11] Published Patent Publication 10-2003-0065719

[Document 12] Seo, Seong-hwan. Trend of hair cosmetics. 128-141.

[Reference 13] Kim Cheong-hoon, Yang Jin-hee, Kim Ae-soon. Effect of Hydrogen Peroxide Concentration and Bleaching Time on Hair Damage. Korean Society of Beauty Science. 2007. 13 (2): 654-662

[Document 14] Na Yun-young, Jung Min-ju, No-Young-bok. Onions ( Allium cepa ) Effect of coat extract on hair microstructure. Journal of the Korean Society of Electronic Microscopy Vol. 38 No. 1 2008 1-8

[Reference 15] Information Sub and Shin Min-kyo, Hyang-Yaksa Dictionary, pp.1014-1015, Younglimsa, 1998

The hair has a life span of 2 to 6 years, but the hair may be damaged by chemical factors such as perm, dyeing, hair dryer, sunlight, sea water, swimming pools, and other air pollutants. The damage is caused in the form of deterioration of hair gloss, weakening of the feel, deterioration of elasticity, generation of hair loss, fluttering due to water deterioration, and discoloration of the hair (Seo, Hwan-hwan. Technical trend of hair cosmetics. ).

In general, in the case of hair dyeing, in order to dye in light colors, a decolorizing agent and hydrogen peroxide water are used to remove black or black brown, which is a general hair color tone of Korean hair.

Previous studies have shown that hydrogen peroxide decreases the tensile strength of the hair with treatment concentration and treatment time, and scales and epicuticles on the hair cuticle increase as the concentration of hydrogen peroxide increases (~ 12%) even on the surface of the hair. (Epicuticle) Desquamation (Kim Cheong-hoon, Yang Jin-hee, Ae-sun Kim. Effects of Hydrogen Peroxide Concentration and Decolorization Time on Hair Damage. Korean Journal of Beauty Sciences, 2007. 13 (2): 654-662).

In general, the research and patent (application) trends for hair are mainly health supplements and methods for manufacturing the same, which are effective for preventing hair loss or hair growth (public patent 10-2002-0041048; Published Patent 10-2007-0020969), hair regrowth composition (public patent) 10-2002-0045127), anti-dandruff hair cosmetic composition (Patent 10-2007-0056597), anti-hair loss, hair growth agent and dandruff treatment, characterized in that it is used as a dose and application (published patent 10-2000-0014138; 10-1999-0032659), hair growth promoting composition (Patent 10-2006-0021965; Patent Publication 10-2001-0082716), scalp health (public patent 10-2000-0060181), hair growth promoting (public patent 10-2005 -0097502), citrus essential oils having an effect of improving seborrheic skin disease (Patent No. 10-2003-0065719), etc., mainly researches and patents (application) on hair growth promotion, dandruff prevention, scalp health, etc. To protect against various damage factors. The studies are insufficient.

Aloe leaves are dried leaves of yellow sea wormwood and related plants of the same genus, and known ingredients include cineole, terpinen-4-ol, and beta-caryophyllene. (β-caryophyllene), linalool, artemisia alcohol, camphor and borneol have been reported to contain (Information and Shinmingyo, medicinal metabolism, pp. 1014-1015, Younglimsa, 1998).

Accordingly, the present inventors continue to search for raw materials having excellent stability and hair protection effect against hydrogen peroxide that induces hair damage among herbal extracts that are used as herbal medicines. The present invention was completed by confirming that there is an effect of protecting the surface damage of the hair and increasing the tensile strength.

In order to accomplish the above object, the present invention provides a cosmetic composition having a hair surface protection effect and tensile strength increase effect containing the leaf extract as an active ingredient.

The extract as defined herein includes water, including purified water, lower alcohols having 1 to 4 carbon atoms or mixed solvents thereof, preferably extracts soluble in water.

As defined herein, the "leaf leaves" can be used wormwood, mountain mugwort, yellow sea mugwort, etc., but it is preferable to use yellow sea mugwort.

The cosmetic composition is a hair tonic, hair conditioner, hair essence, hair lotion, hair nutrition lotion, hair shampoo, hair rinse, hair treatment, hair cream, hair nutrition cream, hair moisturizing cream, hair massage cream, hair wax, hair aerosol , Hair pack, nourishment pack, hair soap, hair cleansing foam, hair oil, hair drier, hair preservative, hair dye, hair wave, hair bleach, hair gel, hair glaze, hair dresser, hair lacquer, hair moisturizer, Formulations of hair mousse or hairspray.

Hereinafter, a method of obtaining the herbal extract of the present invention will be described in detail.

The herbal extract of the present invention washes, dries and shreds the leaves, and water containing about 1 to 200 times (w / w), preferably 10 to 100 times (w / w) purified water, Lower alcohols having 1 to 4 carbon atoms or mixed solvents thereof, preferably water, and then cold extraction, hot water extraction, ultrasonic extraction, reflux cooling extraction, etc. at 100 ° C. for 1 hour to 10 hours, preferably 2 hours to 6 hours. Extraction method of, preferably, a first step of obtaining an extract by performing a hot water extraction method; The extract obtained above was filtered with gauze or filter paper, 1st to 5th, preferably 2nd to 4th, and the filtrate was concentrated in a rotary evaporator and the concentrate was concentrated. A second step of producing the dried leaf extract by freeze drying the extract with a lyophilizer after freezing in an ultra low temperature freezer for 1 hour to 20 hours, preferably 5 hours to 15 hours. Through the leaf extract of the present invention can be obtained.

The present invention provides a cosmetic composition having a hair surface protection effect and an increase in tensile strength containing the herbal extract obtained by the above production method as an active ingredient.

The herbal extract obtained by the extraction method was able to confirm that the liver showed a protective effect through the clinical trials using the human body.

The composition having the hair surface protection effect and the tensile strength increasing effect of the present invention is 0.00001 to 50% by weight (w / w), preferably, 0.0001 to 20% by weight (w) of the herbal extract based on the total weight of the composition / w), more preferably 0.1 to 5% by weight (w / w).

However, the composition is not limited thereto, and may vary depending on the condition and progress of the patient.

The composition of the present invention can be used in a variety of hair cosmetics having a hair surface protection effect and an increase in tensile strength. Examples of products to which the composition can be added include, for example, hair tonics, hair conditioners, hair essences, hair lotions, hair nutrition lotions, hair shampoos, hair rinses, hair treatments, hair creams, hair nutrition creams, hair moisturizers. Cream, hair massage cream, hair wax, hair aerosol, hair pack, hair nutrition pack, hair soap, hair cleansing foam, hair oil, hair dryer, hair preservative, hair colorant, hair wave agent, hair bleach, hair gel, hair glaze, Cosmetics such as hair dressers, hair lacquers, hair moisturizers, hair mousses or hair sprays and the like.

Cosmetics of the present invention comprises a composition selected from the group consisting of water-soluble vitamins, oil-soluble vitamins, polymer peptides, polymer polysaccharides, sphingolipids and seaweed extract.

The water-soluble vitamin is not particularly limited as long as it can be compounded in cosmetics. Preferably, vitamin B, vitamin B2, vitamin B6, pyridoxine, pyridoxine hydrochloride, vitamin B12, pantothenic acid, nicotinic acid, nicotinic acid amide, folic acid, vitamin C, And their salts (thiamine hydrochloride, sodium ascorbate, etc.) or derivatives (sodium ascorbic acid-2-phosphate, magnesium ascorbate-2-phosphate etc.) can also be added to water-soluble vitamins . The water-soluble vitamins can be obtained by conventional methods such as microbial transformation, purification from microorganism culture, enzyme or chemical synthesis.

The oil-soluble vitamin may be any compound that can be formulated into cosmetics, but preferably vitamin A, carotene, vitamin D2, vitamin D3, vitamin E (d1-alpha tocopherol, d-alpha tocopherol, d-alpha tocopherol), and the like. And derivatives thereof (ascorbic palmitate, ascorbic stearate, ascorbic acid dipalmitate, dl-alpha tocopherol acetate, dl-alpha tocopherolvitamin E, DL-pantothenyl alcohol, D-pantothenyl alcohol, pantotenylethyl Ethers, etc.) are also included in the oil-soluble vitamins used in the present invention. Oil-soluble vitamins can be obtained by conventional methods such as microbial transformation, purification of microorganism culture, enzyme or chemical synthesis.

The polymeric peptide may be any compound as long as it can be compounded in cosmetics, and examples thereof include collagen, hydrolyzed collagen, gelatin, elastin, hydrolyzed elastin, and keratin. Polymeric peptides can be purified and obtained by conventional methods such as purification from microbial cultures, enzymatic methods or chemical synthesis methods, or can be purified and used from natural products such as dermis and pig silk such as pigs and cattle.

The polymeric polysaccharide may be any compound as long as it can be incorporated in cosmetics, and examples thereof include hydroxyethyl cellulose, xanthan gum, sodium hyaluronate, chondroitin sulfate or a salt thereof (sodium salt, etc.). For example, chondroitin sulfate or its salt, etc. can be normally purified from a mammal or fish.

The sphingolipid may be any compound as long as it can be blended into cosmetics. Preferably, ceramide, phytosphingosine, sphingosaccharide lipid, etc. may be mentioned. Sphingo lipids can usually be purified from mammals, fish, shellfish, yeasts or plants by conventional methods or obtained by chemical synthesis.

The seaweed extract may be any compound as long as it can be blended into cosmetics. Preferably, the seaweed extract may include brown algae extract, red algae extract, green algae extract, and the like. Also, calginine, arginic acid, sodium arginate, Potassium arginate and the like are also included in the seaweed extract used in the present invention. Seaweed extract can be obtained by purification from seaweed by conventional methods.

The cosmetic of the present invention may be blended with other essential ingredients, if necessary, in combination with the essential ingredients.

Other components that may be added include fats and oils, moisturizers, emollients, surfactants, organic and inorganic pigments, organic powders, ultraviolet absorbers, preservatives, fungicides, antioxidants, plant extracts, pH adjusters, alcohols, pigments, flavorings, Blood circulation accelerators, cooling agents, restriction agents, purified water and the like.

Examples of the fat or oil component include ester fats, hydrocarbon fats, silicone fats, fluorine fats, animal fats, and vegetable fats and oils.

As ester fats and oils, glyceryl tri2-ethylhexanoate, cetyl 2-ethylhexanoate, isopropyl myristate, butyl mystinate, isopropyl palmitate, ethyl stearate, octyl palmitate, isocetyl isostearate, and stearic acid Butyl, ethyl linoleate, isopropyl linoleate, ethyl oleate, isocetyl acid isocetyl, isostyl acid isostearyl, isostaryl palmitate, octylate acid octyldodecyl, isostearic acid isetyl, diethyl sebacate, adipine Acid isopropyl, isoalkyl neopentane, tri (capryl, capric acid) glyceryl, trimethyl ethyl trimethylol propane, triisostearic acid trimethylol propane, tetra 2-ethylhexanoic penta erythritol Cetyl caprylate, lauric acid decyl, hexyl laurate, decyl myristin, myristin acid myristyl, myritic acid cetyl, stearyl stearate, decyl oleate, rininooleic acid , Isostearyl laurate, isotridecyl myristin, isocetyl palmitate, octyl stearate, isocetyl stearate, isodecate oleate, octylate decyl oleate, octyl dodecyl linoleate, isopropyl isopropyl acid, 2 -Cetostearyl ethylhexanoate, stearyl 2-ethylhexanoate, hexyl isostearate, ethylene glycol dioctanoate, ethylene glycol dioleate, propylene glycol dicapric acid, propylene glycol dicacapate, capric acid Propylene glycol, dicapric acid neopentyl glycol, dioctanoate neopentyl glycol, tricaprylic acid glyceryl, triundecyl glyceryl, triisopalmitinate glyceryl, triisostearate glyceryl, neopentane dodecyl Isostearyl octanoate, octyl isononate, hexyl decyl neodecanoate, octyl dodecyl neodecanoate, isocetyl isostearate, isostearyl isostearate, Sothete octylate, polyglycerol oleate, polyglycerine isostearate, triisocetyl citrate, triisoalkyl citrate, triisoctyl citrate, lauryl lactate, myritic lactate, octyl lactate, octyl lactate, tricitric acid Ethyl, acetyl triethyl citrate, acetyl tributyl citrate, trioctyl citrate, diisostearyl malic acid, 2-ethylhexyl hydroxystearate, di2-ethylhexyl succinate, diisobutyl adipicate, diisopropyl sebacinate, Dioctyl sebacate, cholesteryl stearate, cholesteryl isostearate, cholesteryl hydroxystearate, cholesteryl oleate, dihydrocholesteryl oleate, physteryl isostearate, phytic oleate, 12-Steloylhydroxystearate isocetyl, 12-Steloylhydroxystearate stearyl, 12-stealo Esters such as monohydroxystearic acid isostearyl; and the like.

Hydrocarbon-based fats and oils, such as squalene, a liquid paraffin, alpha-olefin oligomer, isoparaffin, ceresin, paraffin, a liquid isoparaffin, polybutene, microcrystal wax, and a vaseline, etc. are mentioned as a hydrocarbon-type fats and oils.

Examples of the silicone-based oils and fats include polymethylsilicone, methylphenylsilicone, methylcyclopolysiloxane, octamethylpolysiloxane, decamethylpolysiloxane, dodecamethylcyclosiloxane, dimethylsiloxane, methylcetyloxysiloxane copolymer, dimethylsiloxane and methylsteoxysiloxane copolymer, and alkyl. Modified silicone oil, amino modified silicone oil and the like.

Examples of the fluorine-based oil include perfluoropolyether and the like.

Animal or vegetable oils include avocado oil, almond oil, olive oil, sesame oil, rice bran oil, soybean oil, soybean oil, corn oil, rapeseed oil, almond oil, palm kernel oil, palm oil, castor oil, sunflower oil, grape seed oil. , Cottonseed oil, Palm oil, Cucumber nut oil, Wheat germ oil, Rice germ oil, Shea butter, Walnut colostrum oil, Marker demia nut oil, Meadow home oil, Egg yolk oil, Uji, Horse oil, Mink oil, Orange rape oil, Jojoba oil And animal or plant fats and oils such as candeler wax, carnava wax, liquid lanolin and hardened castor oil.

Examples of the moisturizing agent include a water-soluble low molecular moisturizer, a fat-soluble molecular moisturizer, a water-soluble polymer, and a fat-soluble polymer.

Water-soluble low molecular humectants include serine, glutamine, sorbitol, mannitol, pyrrolidone-sodium carboxylate, glycerin, propylene glycol, 1,3-butylene glycol, ethylene glycol, polyethylene glycol B (polymerization degree n = 2 or more), polypropylene Glycol (polymerization degree n = 2 or more), polyglycerol B (polymerization degree n = 2 or more), lactic acid, lactic acid salt, etc. are mentioned.

Examples of the fat-soluble low molecular humectants include cholesterol and cholesterol esters.

Examples of the water-soluble polymer include carboxyvinyl polymer, polyasparaginate, tragacanth, xanthan gum, methyl cellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, carboxymethyl cellulose, water soluble chitin, chitosan, and dextrin. Can be.

Examples of the fat-soluble polymers include polyvinylpyrrolidone-eicosene copolymers, polyvinylpyrrolidone-hexadecene copolymers, nitrocellulose, dextrin fatty acid esters, polymer silicones, and the like.

Examples of the emollient include long-chain acyl glutamic acid cholesteryl esters, hydroxy stearic acid cholesterol, 12-hydroxystearic acid, stearic acid, rosin acid, lanolin fatty acid cholesteryl esters, and the like.

As surfactant, nonionic surfactant, anionic surfactant, cationic surfactant, amphoteric surfactant, etc. are mentioned.

As nonionic surfactant, self-emulsifying glycerin monostearate, propylene glycol fatty acid ester, glycerin fatty acid ester, polyglycerol fatty acid ester, sorbitan fatty acid ester, POE (polyoxyethylene) sorbitan fatty acid ester, POE sorbitan fatty acid ester, POE Glycerin Fatty Acid Ester, POE Alkyl Ether, POE Fatty Acid Ester, POE Cured Castor Oil, POE Castor Oil, POE / POP (Polyoxyethylene / Polyoxypropylene) Copolymer, POE / POP Alkyl Ether, Polyether Modified Silicone, Laurin Acid Alkanolamide, alkylamine oxide, hydrogenated soybean phospholipid, etc. are mentioned.

Anionic surfactants include fatty acid soaps, alpha-acyl sulfonates, alkyl sulfonates, alkyl allyl sulfonates, alkyl naphthalene sulfonates, alkyl sulfates, POE alkyl ether sulfates, alkylamide sulfates, alkyl phosphates, POE alkylphosphates, and alkylamides. Phosphates, alkyloylalkyltaurine salts, N-acylamino acid salts, POE alkyl ether carboxylate salts, alkyl sulfosuccinate salts, sodium alkyl sulfo acetates, acylated hydrolyzed collagen peptide salts, perfluoroalkyl phosphate esters, and the like. have.

As cationic surfactant, alkyl trimethylammonium chloride, stearyl trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, cetostearyl trimethyl ammonium chloride, distearyl dimethyl ammonium chloride, stearyl dimethyl benzyl ammonium bromide, behenyl trimethyl ammonium chloride, chloride Benzalkonium, diethylaminoethyl stearate, dimethylaminopropyl stearate, lanolin derivatives, quaternary ammonium salts, and the like.

Examples of amphoteric surfactants include the carboxybetaine type, the amide betain type, the sulfobetain type, the hydroxysulfobetain type, the amide sulfobetain type, the phosphobetaine type, the aminocarboxylate type, the imidazoline derivative type, and the amideamine type. An amphoteric surfactant etc. are mentioned.

Examples of the organic and inorganic pigments include inorganic pigments such as silicic acid, silicic anhydride, magnesium silicate, talc, sericite, mica, kaolin, Bengala, clay, bentonite, titanium mica, titanium oxide, bismuth chloride, zirconium oxide, magnesium oxide, Inorganic pigments such as calcium sulfate, barium sulfate, magnesium sulfate, calcium carbonate, magnesium carbonate, iron oxide, chromium oxide, chromium oxide, chromium hydroxide, Polyamide, polyester, polypropylene, polystyrene, polyurethane, vinyl resin, urea resin, phenol resin, fluorine resin, silicon resin, acrylic resin, melamine resin, epoxy resin, polycarbonate resin, divinylbenzene, styrene copolymer, Organic pigments such as silk powder, cellulose, CI pigment yellow, CI pigment orange, and composite pigments of these inorganic pigments and organic pigments;

As organic powder, Metal soaps, such as a calcium stearate; Alkyl phosphate metal salts such as sodium cetylinate, zinc lauryl acid and calcium laurate; Acylamino acid polyvalent metal salts such as N-lauroyl-beta-alanine calcium, N-lauroyl-beta-alanine zinc, and N-lauroylglycine calcium; Amide sulfonic acid polyvalent metal salts, such as N-lauroyl-taurine calcium and N-palmitoyl-taurine calcium; N-epsilon-lauroyl-L-lysine, N-epsilon-palmitolyzine, N-alpha-paratoylol nitin, N-alpha-lauroyl arginine, N-alpha-cured fatty acid acyl arginine -Acyl basic amino acid; N-acyl polypeptides, such as N-lauroyl glycyl glycine; Alpha-amino fatty acids such as alpha-aminocaprylic acid and alpha-aminolauric acid; Polyethylene, polypropylene, nylon, polymethyl methacrylate, polystyrene, divinylbenzene-styrene copolymer, ethylene tetrafluoride and the like.

Examples of the ultraviolet absorber include paraaminobenzoic acid, ethyl paraaminobenzoate, amyl paraaminobenzoic acid, octyl paraaminobenzoate, ethylene glycol salicylate, phenyl salicylate, octyl salicylate, benzyl salicylate, butylphenyl salicylate, homomentyl salicylic acid and benzyl cinnamic acid. , Paramethoxy cinnamic acid-2-ethoxyethyl, paramethoxy cinnamic acid octyl, diparamethoxy cinnamic acid mono-2-ethylhexaneglyceryl, paramethoxy cinnamic acid isopropyl, diisopropyl diisopropyl cinnamic acid ester mixture, wuro Canonic acid, ethyl urokanoate, hydroxymethoxybenzophenone, hydroxymethoxybenzophenonesulfonic acid and salts thereof, dihydroxymethoxybenzophenone, dihydroxymethoxybenzophenone sodium sulfonate, dihydroxybenzophenone , Tetrahydroxybenzophenone, 4- tert -butyl-4'-methoxydibenzoylmethane, 2,4,6-trianilino- p- (carbo-2'-ethylhexyl-1'-oxy) -1 , 3,5-triazine, 2- (2-hi And the like can be mentioned hydroxy-5-methylphenyl) benzotriazole.

Examples of the disinfectant include hinokitiol, trichloroacid, trichlorohydroxydiphenyl ether, crohexidine gluconate, phenoxyethanol, resorcin, isopropylmethylphenol, azulene, salicylic acid, zinc filitione, benzalkonium chloride, No. 301, mononitro and eicol sodium, and undecylenic acid.

Examples of the antioxidant include butylhydroxyanisole, propyl gallic acid, and erythorbic acid.

Examples of the pH adjuster include citric acid, sodium citrate, malic acid, sodium malate, fmaric acid, sodium pmarate, succinic acid, sodium succinate, sodium hydroxide, sodium dihydrogen phosphate, and the like.

Examples of the alcohol include higher alcohols such as cetyl alcohol.

In addition, the compounding component which may be added other than this is not limited to this, Although any said component can be mix | blended within the range which does not impair the objective and effect of this invention, Preferably it is 0.01 to 5% weight percentage with respect to a total weight, More Preferably 0.01 to 3% by weight.

The cosmetic of the present invention may take the form of a solution, an emulsion, a viscous mixture or the like.

Ingredients included in the cosmetic composition of the present invention may include components commonly used in cosmetic compositions in addition to the herbal extract as an active ingredient, for example, conventional stabilizers, solubilizers, vitamins, pigments and flavorings Adjuvants and carriers.

The cosmetic composition of the present invention may be prepared in any formulation commonly prepared in the art, and includes, for example, milky lotion, cream, lotion, pack, foundation, lotion, essence, hair cosmetic, and the like.

When the formulation of the present invention is a paste, cream or gel, animal fiber, plant fiber, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide may be used as the carrier component .

In the case where the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component. Especially, in the case of a spray, a mixture of chlorofluorohydrocarbons, propane / Propane or dimethyl ether.

In the case of the solution or emulsion of the present invention, a solvent, a solvent or an emulsifier is used as a carrier component, and examples thereof include water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, , 3-butyl glycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan fatty acid esters.

When the formulation of the present invention is a suspension, a carrier such as water, a liquid diluent such as ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, Cellulose, aluminum metahydroxide, bentonite, agar or tracant, etc. may be used.

When the formulation of the present invention is an interfacial active agent-containing cleansing, the carrier component may include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide Ether sulfates, alkylamidobetaines, aliphatic alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, linolenic derivatives or ethoxylated glycerol fatty acid esters.

The hair protection composition containing the leaf extract of the present invention has no side effects or toxicity to the human body, and shows a hair protection effect and an increase in tensile strength through a simple clinical trial, inhibiting hair damage by hydrogen peroxide, increasing tensile strength, and It can be usefully used as a cosmetic composition which shows a scalp protective effect.

1 is a diagram showing the treatment of the hair for electron microscopy,
Figure 2 is a diagram showing the effect of the leaf extract on the surface of the hair,
3 is a diagram showing the treatment of the hair for tensile strength measurement,
4 is a diagram showing the effect of the leaf extract on the tensile strength
5 is a diagram showing the effect of the leaflet and leaflet + hydrogen peroxide number on the cell survival rate,
Figure 6 is a diagram showing the treatment of the hair for the hair wave measurement,
Figure 7 is a diagram showing the wave diameter of each hair.

Hereinafter, the present invention will be described in detail by the following reference examples, examples and experimental examples.

However, the following Reference Examples, Examples and Experimental Examples are merely illustrative of the present invention, and the content of the present invention is not limited by the following Reference Examples, Examples and Experimental Examples.

Reference Example 1. Reagents and Instruments

The hair used in the present invention is a virgin hair of three non-smoking women (22-23 years old: agreed to a hair study) collected at a beauty salon in Sang-dong, Daegu, August 2009. The raw hair was collected from the root of about 20 cm or more from the hair root.

Example  1. Preparation of herbal extracts

150g of the leaves purchased from Daewon Pharmaceutical Co., Ltd. (Daegu, Korea) were washed, dried and shredded, and 1.2L of water was added thereto and then steamed with Daewoong brewing machine (Korea, SER.NO.31237) for 2.5 hours at room temperature. The effluent was first filtered with gauze, filtered using filter paper (No. 2 fiter paper, Nalgene, New York, NY, USA), and the filtrate was then concentrated on a rotary concentrator (EYELA CCA-1110, SER.NO. 10406050). , Tokyo, Japan), the concentrate was frozen in an ultra-low temperature freezer (Ultra-low temperature freezer, SER.NO.090903-01, Operon, Korea) for 12 hours and lyophilizer (EYELA FDU-1100, SER.NO). Lyophilization with .10410378, Tokyo, Japan) yielded 15.3 g (yield 10.2%) of dried petiole extract (hereinafter referred to as “YE”).

Experimental Example  One. Love  extract( YE Protective Effect on the Surface Damage of Hair by Hydrogen Peroxide

In order to confirm the protective effect on the surface damage of the hair of the leaf extract (YE) obtained in Example 1 was experimented as follows by applying the method disclosed in the literature (Kim Chung-un, Yang Jin-hee, Kim Ae-soon, hydrogen peroxide (H ₂ O ₂ ) Effect of concentration and bleaching time on hair damage, Journal of the Korean Society of Aesthetics, 2007, 13 (2), p.654-662).

The same hair was divided into two parts, one end was immersed in water and the other end was immersed in YE (30 mg / ml) for 2 hours, and then dried at room temperature. The dried hair was immersed in 12% hydrogen peroxide (H ₂ O ₂ , DC Chemical Co., Ltd.) for 1 hour and then dried at room temperature. FE-SEM (Field Emission Scanning Electron Microscope, S-4300, HITACHI, Ltd.), a field emission scanning electron microscope, was used to observe the damage on the surface of the hair. Silver-coating was performed with an ion coating machine (ion sputter, E-130, HITACHI, Ltd.) and photographed at a magnification of 700 times (see FIG. 1).

As a result of the experiment, the degree of damage to the hair was observed by field emission scanning electron microscopy (FE-SEM), but the hydrogen peroxide solution showed that the scales of the outer skin of the hair were damaged (see FIG. 2, right hair). Inhibited this injury (see FIG. 2, left hair).

Experimental Example 2 Effect of Leafy Leaf Extract (YE) on Tensile Strength Reduction Induced by Hydrogen Peroxide

In order to confirm the effect on the lowering of the tensile strength of the leaf extract (YE) obtained in Example 1 was tested by applying the method disclosed in the literature (Han Ji-sook, Shin Sung-yeon, Baek Doo-hyun, Ham Mi-young, Ha Byeong-jo, Octylmethoxycinna Study on the hair protection effect of sunscreen products containing mate, Korean Journal of Hair Scalp Hairdressing, 2007, 3 (2), p.59-67).

Two hairs with a diameter of 1.0 ± 0.1 mm were selected through a microscope. The hairs were immersed in water and YE (30 mg / ml) for 2 hours, and then dried at room temperature. The dried hair was immersed in 12% hydrogen peroxide (H ₂ O ₂ , DC Chemical Co., Ltd.) for 1 hour and then dried at room temperature. Rheometer (Fudoh Rheo Meter, Rheotech Co., Ltd.) was used to measure the tensile strength of the hair (see FIG. 3). The tensile strength was expressed as a percentage of the normal group.

As a result, the hair without any treatment showed 100.00 ± 1.65%, but the hair treated with hydrogen peroxide solution showed 72.77 ± 2.87%, indicating a significant decrease in tensile strength. However, the pretreatment with YE showed a significant increase in tensile strength as 95.66 ± 3.84% (see FIG. 4).

Experimental Example 3. Effect of Leafy Leaf Extract (YE) on HaCaT Cells

In order to identify the HaCaT cells of the lobar extract obtained in Example 1, experiments were carried out as follows (Alena Svobodov, Daniela Walterov, Jitka Psotov, Influence of silymarin and its flavonolignans on). H ₂ O ₂ -induced oxidative stress in human keratinocytes and mouse fibroblasts, Burns, 2006, 32 (8), p.973-979).

To measure the cell viability of YE on keratinocytes (HaCaT cells, donated by Yeungnam University College of Pharmacy), keratinocytes were treated with 10% bovine serum (FBS, GibcoBRL, Braunschweig). , Germany) and DMEM / F12 (Dulbecco's modified Eagle's medium / F12, GibcoBRL, Braunschweig, Germany) medium with 100 U / ml penicillin and 100 ug / ml streptomycin (streptomycin, GibcoBRL, Braunschweig, Germany) 5% CO ₂ , was used in the experiment while incubating in a 37 ° C cell culture.

HaCaT cells were dispensed into 24 well plates at 1x10 ⁵ cells / well, and cell viability was obtained after YE treatment alone and in combination with hydrogen peroxide. After incubation, the cells were treated with 3- (4,5- (dimethylthiazol) -2-yl) -2,5-diphenyltetrazolium, MTT, Sigma, St. Louis, MO, USA) After 300ul of 1.0 mg / ml was incubated for 4 hours, the medium was carefully removed, and the resulting formazan crystals were dissolved in DMSO to form a Titertec Multiscan Automatic Elisa Microplate Reader ( Absorbance was measured at 570 nm using a Titertek Multiskan Automatic ELISA microplate reader, Model MCC / 340, Huntsville, AL). Cell viability was expressed as a percentage of the control cell using the formula shown in Equation 1 below.

When YE is treated on the head, it may also affect the scalp. Thus, in order to evaluate cytotoxicity, the cell viability was evaluated using HaCaT cells.

As a result of the experiment, the leaflets did not show any cytotoxicity when treated with a concentration of 0.01 mg / ml for 12 hours (see FIG. 5A), and compared to the hydrogen peroxide alone group even when the leaflets were combined with hydrogen peroxide. There was no cytotoxicity (see FIG. 5B).

These results indicate that even if YE is developed and used as a hair cosmetic, it does not show any toxic effect on the scalp.

Experimental Example  4. Love  extract( YE ) Two hairs wave Impact on

In order to confirm the influence on the wave of the hair of the leaf extract (YE) obtained in Example 1, the experiment described in the literature was applied as follows.

Two hairs with a diameter of 1.0 ± 0.1 mm were selected through a microscope. The hairs were immersed in water and YE (30 mg / ml) for 2 hours and then dried at room temperature. The dried hair was immersed in 12% hydrogen peroxide (H ₂ O ₂ , DC Chemical Co., Ltd.) for 1 hour and then dried at room temperature. In order to observe the curling change of the hair, a 130 ° C Vidal Sasson Long Lasting curling iron (VSCD821C, C, Millplan Industries Ltd.) was used for 10 minutes, and the change in diameter after 24 hours was observed (Fig. 6).

The leaflets inhibit hair damage caused by hydrogen peroxide and do not show significant toxic effects on HaCaT cells, but should not adversely affect the various aesthetic presentations of the hair. For this reason, in this study, the diameter of the wave was observed after 24 hours after the wave was made on the head using an electric head iron making wave on the head.

As a result of the above experiments, the hair treated with no treatment, the hair treated with hydrogen peroxide, and the hair treated with YE + hydrogen peroxide did not show any significant difference (see FIG. 7).

These results indicate that even if YE is developed and used as a hair-only cosmetic, it does not affect the aesthetic wave of hair.

In the present specification, some of the various manufacturing and analysis experiments performed by the present invention have been described as an example, and the technical spirit of the present invention is not limited thereto, and may be variously applied.

Hereinafter, the preparation examples of the composition including the extract of the present invention, but the present invention is not intended to limit it, but is intended to explain in detail only.

Formulation example  1. Manufacture of hair tonic

Resorcinol 0.1%

Menthol 0.05%

Panthenol 0.2%

Salicylic Acid 0.1%

Tocopheryl Acetate 0.1%

Pyridoxine hydrochloride 0.1%

Castor Oil 5.0%

YE extract 10.0%

Pigment amount

Spices

Ethanol

Purified water level

Total 100.0%

Formulation example  2. Hair Conditioner  Produce

Cetanol 3.5%

Self-emulsifying glycerin monostearate 1.5%

Propylene Glycol 2.5%

Stearylmethylbenzyl Ammonium Chloride (25%) 7.0%

0.3% methyl paraoxybenzoate

YE extract 2.5%

Pigment amount

Spices

Purified water level

Total 100.0%

Formulation example  3. Hair lotion  Produce

Resorcinol 2.0%

Menthol 2.0%

Panthenol 0.5%

Pyroctonolamine 0.1%

YE Extract 5.0%

Fragrance, pigment 0.5%

Purified water level

Total 100.0%

Formulation example  4. Hair soap  Produce

YE Extract 0.1%

Titanium dioxide 0.2%

Polyethylene Glycol 0.8%

Glycerin 0.5%

Ethylenediaminetetraacetic Acid 0.05%

Sodium 1.0%

Pigment amount

Soap flavor

Cosmetic soap base (13% moisture, parts by weight)

Total 100.0%

Claims (6)

Washing, drying, and cutting the yellow seaweed leaves, adding water 10 times to 100 times (w / w) of the total weight, and performing a hot water extraction method at 100 ° C. for 1 hour to 10 hours to obtain an extract. step; The extract obtained above was filtered through gauze or filter paper, filter 1 to 5, concentrating the filtrate in a rotary evaporator, and concentrating the concentrate in an ultra low temperature freezer. After freezing for 1 to 20 hours, the extract is freeze-dried with a lyophilizer cosmetic composition having a hair surface protection effect and tensile strength increase effect containing the water extract of dried yellow seaweed leaves as an active ingredient. delete delete The method of claim 1,
The cosmetic composition is a hair tonic, hair conditioner, hair essence, hair lotion, hair nutrition lotion, hair shampoo, hair rinse, hair treatment, hair cream, hair nutrition cream, hair moisturizing cream, hair massage cream, hair wax, hair aerosol , Hair pack, hair nutrition pack, hair soap, hair cleansing foam, hair oil, hair dryer, hair preservative, hair dye, hair wave, hair bleach, hair gel, hair glaze, hair dresser, hair lacquer, hair moisturizer, Cosmetic composition which is a formulation of hair mousse or hairspray. The cosmetic composition of claim 1 comprising 0.00001 to 50% by weight (w / w) of the herbal extract relative to the total weight of the composition. delete

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