KR101213894B1 - Ｔｈ2 매개성 병태를 치료하기 위한 ｋｉｍ-1 항체 - Google Patents

Ｔｈ2 매개성 병태를 치료하기 위한 ｋｉｍ-1 항체 Download PDF

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Publication number
KR101213894B1
KR101213894B1 KR1020077022608A KR20077022608A KR101213894B1 KR 101213894 B1 KR101213894 B1 KR 101213894B1 KR 1020077022608 A KR1020077022608 A KR 1020077022608A KR 20077022608 A KR20077022608 A KR 20077022608A KR 101213894 B1 KR101213894 B1 KR 101213894B1
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South Korea
Prior art keywords
antibody
delete delete
kim
antigen
binding fragment
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Expired - Fee Related
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KR1020077022608A
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English (en)
Korean (ko)
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KR20070110411A (ko
Inventor
폴 디. 렌너트
패트리샤 맥쿤
베로니끄 바일리
알렉세이 루고프스코이
Original Assignee
바이오겐 아이덱 엠에이 인코포레이티드
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Publication of KR20070110411A publication Critical patent/KR20070110411A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020077022608A 2005-03-02 2006-03-02 Ｔｈ2 매개성 병태를 치료하기 위한 ｋｉｍ-1 항체 Expired - Fee Related KR101213894B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65778905P 2005-03-02 2005-03-02
US60/657,789 2005-03-02

Publications (2)

Publication Number Publication Date
KR20070110411A KR20070110411A (ko) 2007-11-16
KR101213894B1 true KR101213894B1 (ko) 2012-12-20

Family

ID=36648475

Family Applications (1)

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KR1020077022608A Expired - Fee Related KR101213894B1 (ko) 2005-03-02 2006-03-02 Ｔｈ2 매개성 병태를 치료하기 위한 ｋｉｍ-1 항체

Country Status (14)

Country Link
US (2) US8206705B2 (cg-RX-API-DMAC7.html)
EP (2) EP1865985B1 (cg-RX-API-DMAC7.html)
JP (2) JP2008531719A (cg-RX-API-DMAC7.html)
KR (1) KR101213894B1 (cg-RX-API-DMAC7.html)
CN (2) CN101166542A (cg-RX-API-DMAC7.html)
AT (1) ATE478707T1 (cg-RX-API-DMAC7.html)
AU (2) AU2006218489B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0608254A2 (cg-RX-API-DMAC7.html)
CA (1) CA2599967C (cg-RX-API-DMAC7.html)
DE (1) DE602006016413D1 (cg-RX-API-DMAC7.html)
IL (1) IL185653A (cg-RX-API-DMAC7.html)
NZ (1) NZ562045A (cg-RX-API-DMAC7.html)
WO (1) WO2006094134A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200708372B (cg-RX-API-DMAC7.html)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008064031A2 (en) * 2006-11-13 2008-05-29 Government Of The United States, As Represented Bythe Secretary Of The Department Of Health And Human Services Potent activation of antigen presenting cells by the hepatitis a virus cellular receptor 1 and its role in the regulation of immune responses
CA2833785C (en) 2011-04-21 2022-06-07 The Regents Of The University Of Colorado, A Body Corporate Compositions and methods for the treatment of neuromyelitis optica
MA43135A (fr) 2015-10-30 2018-09-05 Aleta Biotherapeutics Inc Compositions et méthodes pour le du traitement du cancer
BR112018008390A2 (pt) 2015-10-30 2018-11-27 Aleta Biotherapeutics Inc composições e métodos para transdução tumoral

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002098920A1 (en) 2001-06-01 2002-12-12 Biogen, Inc. Molecules and methods for inhibiting shedding of kim-1

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US5179017A (en) 1980-02-25 1993-01-12 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
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IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
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Also Published As

Publication number Publication date
WO2006094134A3 (en) 2006-10-19
HK1118007A1 (en) 2009-01-30
ATE478707T1 (de) 2010-09-15
BRPI0608254A2 (pt) 2009-12-08
CN101166542A (zh) 2008-04-23
DE602006016413D1 (de) 2010-10-07
IL185653A0 (en) 2008-01-06
EP2251037A1 (en) 2010-11-17
EP2251037B1 (en) 2015-01-14
KR20070110411A (ko) 2007-11-16
AU2011202405B2 (en) 2013-03-28
JP2012131825A (ja) 2012-07-12
CA2599967A1 (en) 2006-09-08
EP1865985A2 (en) 2007-12-19
US8206705B2 (en) 2012-06-26
AU2011202405A1 (en) 2011-06-09
WO2006094134A2 (en) 2006-09-08
EP1865985B1 (en) 2010-08-25
IL185653A (en) 2013-04-30
AU2006218489B2 (en) 2011-02-24
CN103751780A (zh) 2014-04-30
CA2599967C (en) 2014-10-21
US20100150905A1 (en) 2010-06-17
ZA200708372B (en) 2008-12-31
NZ562045A (en) 2010-12-24
AU2006218489A1 (en) 2006-09-08
JP2008531719A (ja) 2008-08-14
US20130089539A1 (en) 2013-04-11

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