ATE478707T1 - Kim-1-antikörper zur behandlung von th2- vermittelten erkrankungen - Google Patents
Kim-1-antikörper zur behandlung von th2- vermittelten erkrankungenInfo
- Publication number
- ATE478707T1 ATE478707T1 AT06736714T AT06736714T ATE478707T1 AT E478707 T1 ATE478707 T1 AT E478707T1 AT 06736714 T AT06736714 T AT 06736714T AT 06736714 T AT06736714 T AT 06736714T AT E478707 T1 ATE478707 T1 AT E478707T1
- Authority
- AT
- Austria
- Prior art keywords
- kim
- antibodies
- treatment
- mediated diseases
- mediated
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 102100034459 Hepatitis A virus cellular receptor 1 Human genes 0.000 title 1
- 101710185991 Hepatitis A virus cellular receptor 1 homolog Proteins 0.000 title 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65778905P | 2005-03-02 | 2005-03-02 | |
| PCT/US2006/007441 WO2006094134A2 (en) | 2005-03-02 | 2006-03-02 | Kim-1 antibodies for treatment of th2-mediated conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE478707T1 true ATE478707T1 (de) | 2010-09-15 |
Family
ID=36648475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06736714T ATE478707T1 (de) | 2005-03-02 | 2006-03-02 | Kim-1-antikörper zur behandlung von th2- vermittelten erkrankungen |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8206705B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP1865985B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2008531719A (cg-RX-API-DMAC7.html) |
| KR (1) | KR101213894B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN101166542A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE478707T1 (cg-RX-API-DMAC7.html) |
| AU (2) | AU2006218489B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0608254A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2599967C (cg-RX-API-DMAC7.html) |
| DE (1) | DE602006016413D1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL185653A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ562045A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006094134A2 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200708372B (cg-RX-API-DMAC7.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008064031A2 (en) * | 2006-11-13 | 2008-05-29 | Government Of The United States, As Represented Bythe Secretary Of The Department Of Health And Human Services | Potent activation of antigen presenting cells by the hepatitis a virus cellular receptor 1 and its role in the regulation of immune responses |
| CA2833785C (en) | 2011-04-21 | 2022-06-07 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for the treatment of neuromyelitis optica |
| MA43135A (fr) | 2015-10-30 | 2018-09-05 | Aleta Biotherapeutics Inc | Compositions et méthodes pour le du traitement du cancer |
| BR112018008390A2 (pt) | 2015-10-30 | 2018-11-27 | Aleta Biotherapeutics Inc | composições e métodos para transdução tumoral |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| DE3883899T3 (de) | 1987-03-18 | 1999-04-22 | Sb2, Inc., Danville, Calif. | Geänderte antikörper. |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5789650A (en) | 1990-08-29 | 1998-08-04 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| DK0590058T3 (da) | 1991-06-14 | 2004-03-29 | Genentech Inc | Humaniseret heregulin-antistof |
| ATE182625T1 (de) | 1993-01-12 | 1999-08-15 | Biogen Inc | Rekombinante anti-vla4 antikörpermoleküle |
| US5827690A (en) | 1993-12-20 | 1998-10-27 | Genzyme Transgenics Corporatiion | Transgenic production of antibodies in milk |
| US5622861A (en) | 1994-08-05 | 1997-04-22 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA encoding hepatitis A virus receptor |
| US6066322A (en) | 1995-03-03 | 2000-05-23 | Millennium Pharmaceuticals, Inc. | Methods for the treatment of immune disorders |
| WO1996034096A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| DE19541844C1 (de) | 1995-11-09 | 1997-07-24 | Gsf Forschungszentrum Umwelt | Verfahren zur Herstellung von menschlichen Antikörpern und deren Verwendung |
| US6165733A (en) | 1996-05-23 | 2000-12-26 | Chiron Corporation | γ II adaptin |
| CN1147584C (zh) | 1996-05-24 | 2004-04-28 | 拜奥根有限公司 | 组织再生调节物 |
| JP2001503271A (ja) | 1996-11-01 | 2001-03-13 | ヒューマン ジノーム サイエンシーズ,インコーポレイテッド | ヒト粘膜アドレシン細胞接着分子―1(MAdCAM―1)およびそのスプライス変異体 |
| EP2305027B1 (en) | 1996-12-03 | 2014-07-02 | Amgen Fremont Inc. | Transgenic mammals having human Ig loci including plural VH and Vkappa regions and antibodies produced therefrom |
| CA2274250A1 (en) | 1996-12-06 | 1998-06-11 | Vertex Pharmaceuticals Incorporated | Inhibitors of interleukin-1.beta. converting enzyme |
| CN101274962A (zh) | 1998-01-23 | 2008-10-01 | 霍夫曼-拉罗奇有限公司 | 人il-12抗体 |
| KR20010041765A (ko) | 1998-03-11 | 2001-05-25 | 가마쿠라 아키오 | IgE 항체생산 억제제 및 자기면역질환 억제제 |
| US6228642B1 (en) | 1998-10-05 | 2001-05-08 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide modulation of tumor necrosis factor-(α) (TNF-α) expression |
| US8288322B2 (en) | 2000-04-17 | 2012-10-16 | Dyax Corp. | Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries |
| ATE425249T1 (de) | 2000-06-16 | 2009-03-15 | Biogen Idec Inc | Renale regulatorische elemente und deren verwendung |
| EP1401869B1 (en) * | 2001-06-01 | 2007-12-26 | Biogen Idec MA Inc. | Molecules and methods for inhibiting shedding of kim-1 |
| US7838220B2 (en) | 2001-06-29 | 2010-11-23 | The Board Of Trustees Of The Leland Stanford Junior University | T cell regulatory genes associated with immune disease |
| US7553939B2 (en) | 2001-06-29 | 2009-06-30 | The Board Of Trustees Of The Leland Stanford Junior University | T cell regulatory genes and methods of use thereof |
| EP1434881A4 (en) | 2001-09-17 | 2005-10-26 | Protein Design Labs Inc | METHOD FOR DIAGNOSIS OF CANCER COMPOSITIONS AND METHOD FOR SCREENING ON CANCER MODULATORS |
| WO2003042661A2 (en) | 2001-11-13 | 2003-05-22 | Protein Design Labs, Inc. | Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer |
| US7687454B2 (en) | 2001-12-03 | 2010-03-30 | The University Of British Columbia | Effectors of innate immunity determination |
| WO2003063792A2 (en) | 2002-01-30 | 2003-08-07 | The Brigham And Women's Hospital, Inc. | Compositions and methods related to tim-3, a th1-specific cell surface molecule |
| US20050014687A1 (en) | 2002-03-19 | 2005-01-20 | Anderson David W. | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| GB0215509D0 (en) | 2002-07-04 | 2002-08-14 | Novartis Ag | Marker genes |
| DE60322744D1 (de) | 2002-12-30 | 2008-09-18 | Biogen Idec Inc | Kim-1-antagonisten und verwendung zur immunsystemmodulation |
| EP3000886A1 (en) * | 2003-03-19 | 2016-03-30 | Amgen Fremont Inc. | Antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen and uses thereof |
| WO2005001092A2 (en) | 2003-05-20 | 2005-01-06 | Wyeth | Compositions and methods for diagnosing and treating cancers |
| TW200539890A (en) | 2004-03-12 | 2005-12-16 | Brigham & Womens Hospital | Methods of modulating immune responses by modulating tim-1, tim-2 and tim-4 function |
| CA2560941A1 (en) | 2004-03-24 | 2005-10-20 | Telos Pharmaceuticals Llc | Compositions as adjuvants to improve immune responses to vaccines and methods of use |
| US8025557B2 (en) | 2009-02-27 | 2011-09-27 | Illinois Tool Works Inc. | Sanding clay |
-
2006
- 2006-03-02 AU AU2006218489A patent/AU2006218489B2/en not_active Ceased
- 2006-03-02 CN CNA2006800139893A patent/CN101166542A/zh active Pending
- 2006-03-02 KR KR1020077022608A patent/KR101213894B1/ko not_active Expired - Fee Related
- 2006-03-02 US US11/817,638 patent/US8206705B2/en not_active Expired - Fee Related
- 2006-03-02 NZ NZ562045A patent/NZ562045A/en not_active IP Right Cessation
- 2006-03-02 EP EP06736714A patent/EP1865985B1/en active Active
- 2006-03-02 CA CA2599967A patent/CA2599967C/en not_active Expired - Fee Related
- 2006-03-02 CN CN201410043208.1A patent/CN103751780A/zh active Pending
- 2006-03-02 EP EP10173620.5A patent/EP2251037B1/en not_active Not-in-force
- 2006-03-02 WO PCT/US2006/007441 patent/WO2006094134A2/en not_active Ceased
- 2006-03-02 BR BRPI0608254-8A patent/BRPI0608254A2/pt not_active IP Right Cessation
- 2006-03-02 JP JP2007558223A patent/JP2008531719A/ja not_active Withdrawn
- 2006-03-02 AT AT06736714T patent/ATE478707T1/de not_active IP Right Cessation
- 2006-03-02 DE DE602006016413T patent/DE602006016413D1/de active Active
-
2007
- 2007-09-02 IL IL185653A patent/IL185653A/en not_active IP Right Cessation
- 2007-10-01 ZA ZA200708372A patent/ZA200708372B/xx unknown
-
2011
- 2011-05-24 AU AU2011202405A patent/AU2011202405B2/en not_active Ceased
-
2012
- 2012-03-28 JP JP2012073852A patent/JP2012131825A/ja active Pending
- 2012-04-04 US US13/439,413 patent/US20130089539A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006094134A3 (en) | 2006-10-19 |
| HK1118007A1 (en) | 2009-01-30 |
| BRPI0608254A2 (pt) | 2009-12-08 |
| CN101166542A (zh) | 2008-04-23 |
| DE602006016413D1 (de) | 2010-10-07 |
| IL185653A0 (en) | 2008-01-06 |
| KR101213894B1 (ko) | 2012-12-20 |
| EP2251037A1 (en) | 2010-11-17 |
| EP2251037B1 (en) | 2015-01-14 |
| KR20070110411A (ko) | 2007-11-16 |
| AU2011202405B2 (en) | 2013-03-28 |
| JP2012131825A (ja) | 2012-07-12 |
| CA2599967A1 (en) | 2006-09-08 |
| EP1865985A2 (en) | 2007-12-19 |
| US8206705B2 (en) | 2012-06-26 |
| AU2011202405A1 (en) | 2011-06-09 |
| WO2006094134A2 (en) | 2006-09-08 |
| EP1865985B1 (en) | 2010-08-25 |
| IL185653A (en) | 2013-04-30 |
| AU2006218489B2 (en) | 2011-02-24 |
| CN103751780A (zh) | 2014-04-30 |
| CA2599967C (en) | 2014-10-21 |
| US20100150905A1 (en) | 2010-06-17 |
| ZA200708372B (en) | 2008-12-31 |
| NZ562045A (en) | 2010-12-24 |
| AU2006218489A1 (en) | 2006-09-08 |
| JP2008531719A (ja) | 2008-08-14 |
| US20130089539A1 (en) | 2013-04-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |