KR101188013B1 - 핵산 발현의 개선을 위한 신규한 서열 - Google Patents

핵산 발현의 개선을 위한 신규한 서열 Download PDF

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KR101188013B1
KR101188013B1 KR1020067027165A KR20067027165A KR101188013B1 KR 101188013 B1 KR101188013 B1 KR 101188013B1 KR 1020067027165 A KR1020067027165 A KR 1020067027165A KR 20067027165 A KR20067027165 A KR 20067027165A KR 101188013 B1 KR101188013 B1 KR 101188013B1
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nucleic acid
sequence
suppressor
promoter
interest
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Expired - Fee Related
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English (en)
Korean (ko)
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KR20070042122A (ko
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아리이 피터 오떼
테오도루스 헨드리쿠스 야코부스 콱스
리차르드 게오르그 안토니우스 베르나르두스 세발트
헨리쿠스 요하네스 마리아 반 블록란트
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크로마제닉스 비.브이.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020067027165A 2004-07-08 2005-07-07 핵산 발현의 개선을 위한 신규한 서열 Expired - Fee Related KR101188013B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US58700704P 2004-07-08 2004-07-08
EPPCT/EP2004/051405 2004-07-08
US60/587,007 2004-07-08
EP2004051405 2004-07-08
PCT/EP2005/053251 WO2006005718A2 (en) 2004-07-08 2005-07-07 Novel sequence for improving expression of nucleic acid

Publications (2)

Publication Number Publication Date
KR20070042122A KR20070042122A (ko) 2007-04-20
KR101188013B1 true KR101188013B1 (ko) 2012-10-08

Family

ID=34971366

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067027165A Expired - Fee Related KR101188013B1 (ko) 2004-07-08 2005-07-07 핵산 발현의 개선을 위한 신규한 서열

Country Status (19)

Country Link
US (1) US7825232B2 (enExample)
JP (1) JP4805262B2 (enExample)
KR (1) KR101188013B1 (enExample)
CN (1) CN1981057B (enExample)
AT (1) ATE378426T1 (enExample)
AU (1) AU2005261699B2 (enExample)
BR (1) BRPI0512798A (enExample)
CA (1) CA2573022C (enExample)
DE (1) DE602005003369T2 (enExample)
DK (1) DK1763586T3 (enExample)
EA (1) EA011747B1 (enExample)
ES (1) ES2296201T3 (enExample)
IL (1) IL180531A (enExample)
MX (1) MXPA06014553A (enExample)
NO (1) NO341862B1 (enExample)
NZ (1) NZ551510A (enExample)
PT (1) PT1763586E (enExample)
WO (1) WO2006005718A2 (enExample)
ZA (1) ZA200610470B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1572994T3 (da) * 2002-12-20 2007-05-29 Chromagenics Bv Midler og fremgangsmåder til fremstilling af en protein gennem chromatinåbnere, som kan göre chromatin mere tilgængeligt for transkriptionsfaktorer
BRPI0517380A (pt) * 2004-11-08 2008-10-07 Chromagenics Bv molécula de dna, cassete de expressão, célula hospedeira, e, métodos para gerar uma célula hospedeira que expressa um polipeptìdeo de interesse e para produzir um polipeptìdeo de interesse
US8999667B2 (en) * 2004-11-08 2015-04-07 Chromagenics B.V. Selection of host cells expressing protein at high levels
US8039230B2 (en) 2004-11-08 2011-10-18 Chromagenics B.V. Selection of host cells expressing protein at high levels
NZ553700A (en) 2004-11-08 2010-09-30 Chromagenics Bv Selection of host cells expressing protein at high levels using a selectable marker with a non-optimal start codon
US20100136616A1 (en) * 2004-11-08 2010-06-03 Chromagenics B.V. Selection of Host Cells Expressing Protein at High Levels
US20060195935A1 (en) 2004-11-08 2006-08-31 Chromagenics B.V. Selection of host cells expressing protein at high levels
CN102459607B (zh) * 2009-06-15 2014-08-06 萨拉基尼克有限公司 新的严格的可选择的标志物
BR112012031694A2 (pt) 2010-06-15 2016-02-16 Cellagenics B V fragmento de ácido nucleíco, construto de ácido nucleíco, vetor de expressão, célula hospedeira, método de geração de uma célula hospedeira para a expressão de um produto gênico de interesse, e, método de expresão de um produto de gene de interesse
CN103180443B (zh) 2010-09-01 2016-01-13 萨拉基尼克有限公司 用于增强基因表达的来自核糖体蛋白启动子的核酸片段
CN110484563B (zh) * 2019-07-25 2023-04-07 新乡医学院 哺乳动物细胞组合表达载体、表达系统、制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60237048D1 (de) * 2001-07-04 2010-08-26 Chromagenics Bv DNS-Sequenzen mit Anti-Repressor-Aktivität
CA2489475C (en) 2002-06-14 2011-03-29 Chromagenics B.V. A method for simultaneous production of multiple proteins; vectors and cells for use therein
DK1572994T3 (da) * 2002-12-20 2007-05-29 Chromagenics Bv Midler og fremgangsmåder til fremstilling af en protein gennem chromatinåbnere, som kan göre chromatin mere tilgængeligt for transkriptionsfaktorer

Also Published As

Publication number Publication date
BRPI0512798A (pt) 2008-04-08
DK1763586T3 (da) 2008-03-17
WO2006005718A2 (en) 2006-01-19
IL180531A (en) 2011-04-28
HK1097004A1 (en) 2007-06-15
ZA200610470B (en) 2008-09-25
MXPA06014553A (es) 2007-03-12
CA2573022A1 (en) 2006-01-19
CN1981057B (zh) 2012-07-04
CA2573022C (en) 2012-03-06
NZ551510A (en) 2009-10-30
PT1763586E (pt) 2008-02-25
JP4805262B2 (ja) 2011-11-02
NO20070757L (no) 2007-02-08
JP2008505626A (ja) 2008-02-28
AU2005261699B2 (en) 2009-07-23
AU2005261699A1 (en) 2006-01-19
ATE378426T1 (de) 2007-11-15
EA011747B1 (ru) 2009-06-30
ES2296201T3 (es) 2008-04-16
EA200700233A1 (ru) 2007-06-29
WO2006005718A3 (en) 2006-08-17
US7825232B2 (en) 2010-11-02
NO341862B1 (no) 2018-02-12
DE602005003369T2 (de) 2009-03-05
CN1981057A (zh) 2007-06-13
US20070212755A1 (en) 2007-09-13
KR20070042122A (ko) 2007-04-20
IL180531A0 (en) 2007-06-03
DE602005003369D1 (de) 2007-12-27

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