KR101166214B1 - 아이지에프비피-2 및 아이지에프비피-5를 억제하는 양특이성 안티센스 올리고뉴클레오티드 및 그 사용방법 - Google Patents

아이지에프비피-2 및 아이지에프비피-5를 억제하는 양특이성 안티센스 올리고뉴클레오티드 및 그 사용방법 Download PDF

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KR101166214B1
KR101166214B1 KR1020117003991A KR20117003991A KR101166214B1 KR 101166214 B1 KR101166214 B1 KR 101166214B1 KR 1020117003991 A KR1020117003991 A KR 1020117003991A KR 20117003991 A KR20117003991 A KR 20117003991A KR 101166214 B1 KR101166214 B1 KR 101166214B1
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igfbp
antisense
cells
cancer
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KR20110026023A (ko
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마틴 글리브
막심 시냐프스키
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더 유니버시티 오브 브리티쉬 콜롬비아
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/51—Physical structure in polymeric form, e.g. multimers, concatemers

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KR1020117003991A 2002-01-17 2003-01-17 아이지에프비피-2 및 아이지에프비피-5를 억제하는 양특이성 안티센스 올리고뉴클레오티드 및 그 사용방법 Expired - Fee Related KR101166214B1 (ko)

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Application Number Priority Date Filing Date Title
US35004602P 2002-01-17 2002-01-17
US60/350,046 2002-01-17
PCT/CA2003/000061 WO2003062421A1 (en) 2002-01-17 2003-01-17 Bispecific antisense olignucleotides that inhibit igfbp-2 and igfbp-5 and methods of using same

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KR1020047011085A Division KR101265180B1 (ko) 2002-01-17 2003-01-17 아이지에프비피-2 및 아이지에프비피-5를 억제하는 양특이성 안티센스 올리고뉴클레오티드, 이를 이용하여 약학적 조성물을 제조하는 방법 및 그 약학적 조성물

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KR20110026023A KR20110026023A (ko) 2011-03-14
KR101166214B1 true KR101166214B1 (ko) 2012-07-16

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KR1020117003991A Expired - Fee Related KR101166214B1 (ko) 2002-01-17 2003-01-17 아이지에프비피-2 및 아이지에프비피-5를 억제하는 양특이성 안티센스 올리고뉴클레오티드 및 그 사용방법
KR1020047011085A Expired - Fee Related KR101265180B1 (ko) 2002-01-17 2003-01-17 아이지에프비피-2 및 아이지에프비피-5를 억제하는 양특이성 안티센스 올리고뉴클레오티드, 이를 이용하여 약학적 조성물을 제조하는 방법 및 그 약학적 조성물

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EP (1) EP1465995B1 (https=)
JP (1) JP4491240B2 (https=)
KR (2) KR101166214B1 (https=)
AT (1) ATE402999T1 (https=)
AU (1) AU2003237616B2 (https=)
CA (1) CA2469685C (https=)
DE (1) DE60322509D1 (https=)
DK (1) DK1465995T3 (https=)
ES (1) ES2307942T3 (https=)
HU (1) HU229452B1 (https=)
IL (2) IL162540A0 (https=)
NO (1) NO333017B1 (https=)
NZ (1) NZ533126A (https=)
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IL162540A (en) 2011-06-30
US20060122141A1 (en) 2006-06-08
KR101265180B1 (ko) 2013-05-29
NO333017B1 (no) 2013-02-18
ES2307942T3 (es) 2008-12-01
EP1465995A1 (en) 2004-10-13
US20130096180A1 (en) 2013-04-18
US8580761B2 (en) 2013-11-12
NZ533126A (en) 2006-04-28
US20160002630A1 (en) 2016-01-07
JP2005514948A (ja) 2005-05-26
US8389491B2 (en) 2013-03-05
EP1465995B1 (en) 2008-07-30
US8541390B2 (en) 2013-09-24
US20120077861A1 (en) 2012-03-29
US20030158143A1 (en) 2003-08-21
US8252765B2 (en) 2012-08-28
KR20040085150A (ko) 2004-10-07
JP4491240B2 (ja) 2010-06-30
DK1465995T3 (da) 2008-10-20
US9101646B2 (en) 2015-08-11
ATE402999T1 (de) 2008-08-15
NO20043401L (no) 2004-10-13
HUP0402543A2 (hu) 2005-03-29
US8835401B2 (en) 2014-09-16
AU2003237616B2 (en) 2007-07-05
CA2469685C (en) 2013-03-12
US8470796B2 (en) 2013-06-25
CA2469685A1 (en) 2003-07-31
IL162540A0 (en) 2005-11-20
US7973017B2 (en) 2011-07-05
US7928082B2 (en) 2011-04-19
US20130303592A1 (en) 2013-11-14
HU229452B1 (en) 2013-12-30
WO2003062421A1 (en) 2003-07-31
KR20110026023A (ko) 2011-03-14
US20110196019A1 (en) 2011-08-11
US20110190382A1 (en) 2011-08-04
US20120220646A1 (en) 2012-08-30
US20080261912A1 (en) 2008-10-23
US20100267808A1 (en) 2010-10-21
HUP0402543A3 (en) 2012-09-28
DE60322509D1 (de) 2008-09-11

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