KR101149475B1 - 이종 장기 이식용 미니 복제돼지 생산을 위한 유전자 조작된 세포주 및 그의 생산방법 - Google Patents
이종 장기 이식용 미니 복제돼지 생산을 위한 유전자 조작된 세포주 및 그의 생산방법 Download PDFInfo
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- KR101149475B1 KR101149475B1 KR1020080120498A KR20080120498A KR101149475B1 KR 101149475 B1 KR101149475 B1 KR 101149475B1 KR 1020080120498 A KR1020080120498 A KR 1020080120498A KR 20080120498 A KR20080120498 A KR 20080120498A KR 101149475 B1 KR101149475 B1 KR 101149475B1
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| KR101149475B1 true KR101149475B1 (ko) | 2012-05-25 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2012504390A (ja) * | 2008-09-30 | 2012-02-23 | ノボザイムス，インコーポレイティド | 糸状菌細胞におけるポジティブ及びネガティブ選択遺伝子の使用方法 |
| KR101048426B1 (ko) * | 2009-05-27 | 2011-07-11 | 한국생명공학연구원 | 알파 1,3-갈락토실트랜스퍼라아제 유전자의 위치에 ｄａｆ 유전자를 넉인한 체세포 제조 방법 |
| KR101236724B1 (ko) * | 2010-11-23 | 2013-02-26 | 대한민국 | 단백질 과발현 카세트를 포함하는 유전자 타겟팅 넉인 벡터, 이의 제조 방법 및 이 벡터가 도입된 이종간 이식용 형질전환 복제동물 |
| KR101896518B1 (ko) * | 2011-03-30 | 2018-10-24 | 주식회사 툴젠 | Ｃｍａｈ 유전자를 표적으로 하는 징크 핑거 뉴클레아제 및 이의 용도 |
| KR101479671B1 (ko) * | 2011-11-02 | 2015-01-08 | 건국대학교 산학협력단 | Ｃｍｐ－아세틸뉴라미닌산 히드록실라아제 타겟팅 벡터 및 그 응용 |
| DK2993234T3 (en) * | 2013-04-30 | 2019-01-07 | Univ Konkuk Ind Coop Corp | Vector Targeted CMP Acetylneuramic Acid Hydroxylase, Transgenic Animal for Xenotransplantation Introduced with the Vector and Method of Preparation thereof |
| CN108473963A (zh) * | 2015-09-09 | 2018-08-31 | 雷维维科公司 | 用于异种移植的多重转基因猪 |
| KR102363891B1 (ko) * | 2017-04-28 | 2022-02-17 | 서울대학교산학협력단 | ＨＯ-1 유전자 및 ＴＮＦＲ1-Ｆｃ 유전자를 동시에 발현하며 GGTA1 유전자 및 CMAH 유전자가 넉아웃된 형질전환 돼지 및 이의 용도 |
| CN113429475A (zh) * | 2020-03-23 | 2021-09-24 | 成都中科奥格生物科技有限公司 | 一种胶原材料及其制备方法和用途 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6153428A (en) | 1994-04-13 | 2000-11-28 | Biotransplant, Inc. | α(1,3) galactosyltransferase negative porcine cells |
| US6166288A (en) | 1995-09-27 | 2000-12-26 | Nextran Inc. | Method of producing transgenic animals for xenotransplantation expressing both an enzyme masking or reducing the level of the gal epitope and a complement inhibitor |
| JP2006129736A (ja) | 2004-11-02 | 2006-05-25 | Nippon Dobutsu Kogaku Kenkyusho:Kk | 異種移植用豚細胞、その選抜方法及び異種移植用豚 |
| US7166278B2 (en) | 2001-04-30 | 2007-01-23 | Rbc Biotechnology, Inc. | Modified organs and cells for xenotransplantation |
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- 2008-12-01 WO PCT/KR2008/007087 patent/WO2009069986A2/fr active Application Filing
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6153428A (en) | 1994-04-13 | 2000-11-28 | Biotransplant, Inc. | α(1,3) galactosyltransferase negative porcine cells |
| US6166288A (en) | 1995-09-27 | 2000-12-26 | Nextran Inc. | Method of producing transgenic animals for xenotransplantation expressing both an enzyme masking or reducing the level of the gal epitope and a complement inhibitor |
| US7166278B2 (en) | 2001-04-30 | 2007-01-23 | Rbc Biotechnology, Inc. | Modified organs and cells for xenotransplantation |
| JP2006129736A (ja) | 2004-11-02 | 2006-05-25 | Nippon Dobutsu Kogaku Kenkyusho:Kk | 異種移植用豚細胞、その選抜方法及び異種移植用豚 |
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| WO2009069986A2 (fr) | 2009-06-04 |
| KR20090056922A (ko) | 2009-06-03 |
| WO2009069986A3 (fr) | 2009-07-16 |
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